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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 15 Documents
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Search results for , issue "Vol. 55, No. 3" : 15 Documents clear
The Effect of Vitamin E Supplementation on Muscular Fatigue in Professional Men's Athletics Yusni, Yusni; Amiruddin, Amiruddin
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

High-intensity exercise (3000-meter runner) contributes to muscle fatigue. Fatigue can be determined by measuring blood lactate levels. Blood lactate levels are a product of anaerobic metabolism. Lactate accumulation due to anaerobic physical activity can inhibit the glycolytic enzyme that affects decreased ATP production, damage of the calcium and sodium pumps in the muscles and causes fatigue. This study aimed to analyze the effect of vitamin E on the level of fatigue through the response of blood lactate levels in the runner 3000 meters. This research was a quasi-experimental research with a pretest-posttest design. Research subjects were 9 volunteer athletes (3000 meters runners) Aceh province, male, and aged 15-20 years. The treatments were vitamin E at a dose of 1x400 IU per day and administered for 14 days. Blood lactate levels were examined using the method of calorimetry. The statistical analysis was using the homogeneity test of variance (Levene's test), the normality test (Kolmogorov-Smirnov test) and paired t-test with a significant level of 5% (p-value<0.05). The results showed that blood lactate levels decreased approximately 13.93% after vitamin E supplementation. There was no significant difference (p=0.27) between blood lactate levels before and after vitamin E supplementation in athletes. In conclusion, vitamin E supplementation did not significantly lower blood lactate levels therefore vitamin E did not significantly reduce muscle fatigue in men's athletics.
The Influence of Health Education on Diabetes Mellitus on Knowledge Improvement of Diabetes Mellitus Cadres in the Working Area of Medokan Ayu Health Center, Surabaya, Indonesia Andajani, Susilowati
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

This study aimed to analyze the influence of health education on improcing health cadres' knowledge about Diabetes Melitus (DM) at Ayu Medokan Health Center, Surabaya, Indonesia. The type and design of this study was non-randomized pretest-posttest design, with samples of DM cadres in the working area of Medokan Ayu Health Center, Surabaya, Indonesia. Sample size was 24 persons. The treatment variable was health education, while the dependent variable was the increase of the cadres' knowledge about DM. Normality test was performed with Kolmogorov Smirnov (a=0.05) and data analysis with Paired t-test (a=0.05). This study found that DM cadres were mostly female (23 people), with the youngest age 24 years, and the oldest 61 years. The highest age group (45.80%) was 40-49 years with a mean age of 44.37 + 9.27 years. Most of DM cadres' education (62.5%) was senior high school, then junior high school (25%). Most (58.3%) of the DM cadres did not work or as housewives. Besides being a DM cadre, most of them also posyandu and bumantik cadres, 2) There was a significant difference (p<0,0001) between the level of knowledge before and after health education. In conclusion, cadres' knowledge about DM can be improved, among others, by providing health education.
Effect of Combination Soy Bean Oil and Oleic Acid to Characteristic, Penetration, Physical Stability of Nanostructure Lipid Carrier Resveratrol Soeratri, Widji; Hidayah, Rohmawati; Rosita, Noorma
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Resveratrol is an antioxidant that can be used as anti-aging. Topical use has several problems because solubility in water is low and unstable to light. This study aimed to evaluate the effect of the combination of soy bean oil and oleic acid liquid lipids on the characteristics, penetration, and stability of resveratrol nanostructured lipid carriers (NLC). Nanostructured lipid carriers (NLC) were made with high shear homogeneous technique. To determine the characterization of NLC, diffraction scanning calorimetry, X-ray diffraction, and Fourier transforms infrared spectrophotometry were used. Examination of the morphological form was carried out with a transmission electron microscope. The particle size and polydispersity index examination were measured by the Delsa Nanoâ„¢ particle size analyzer, while the efficiency of trapping resveratrol in the NLC system was measured by the dialysis membrane method. Furthermore, the penetration depth test on the skin of mice was done by fluorescence microscope method using rhodamine B markers. Physical stability test was performed by examination of particle size and index polydispersity for 30 days. The formula with liquid soy bean oil and oleic acid liquid lipids improved the characteristics including the effectiveness of entrapment and colloidal stability. However, the formula with soy bean oil and oleic acid combination liquid lipids did not provide better penetration into the skin than the use of single liquid lipids. While the formula with soy bean oil and oleic acid liquid lipids proved to improve the physical stability for 30 days.
Case report: Management of Progressive Lung Cancer Patients after First-Line EGFR Tyrosine Kinase Inhibitor Therapy Sahrun, Sahrun; Wulandari, Laksmi
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Various tyrosine kinase inhibitor (TKI) drugs have been widely used as therapy for cancer that has EGFR mutations, or abnormal EGFR activation. However, patients who have a mutation in the gene that activates EGFR only benefit from EGFR-TKI therapy for less than one year, because after that resistance occurs. In the management of patients according to NCCN 2017, patients who experience progress after receiving TKI as the first-line therapy must undergo an examination to identify the presence of T790M mutation. If the T790M mutation is positive, the choice of therapy that needs to be provided is the third generation (Osimertinib). Many recent studies have proved the significance of the effectiveness and response of Osimertinib therapy in lung cancer with EGFR T790M mutation. We reported the management of a pulmonary adenocarcinoma patient with positive EGFR mutation who had received first-line EGFR TKI who had progressive disease and T790M mutation in Dr. Seotomo Hospital. The patient finally received Osimertinib through an Early Access Program with a therapeutic response that improved significantly.
Determinants of Maternal and Child Health Handbook Utilization in Surabaya, Indonesia Irwanto, Irwanto; Ikhtiar, Ilham; Lutfiya, Indah; Purnomo, Windhu
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Mothers and child health (MCH) are one of the main issues in family medicine. Related to this practice, Indonesian government issued mother and child health (MCH) handbook for monitoring child development due to various child developmental problems in Indonesia. However, there are reports of improper MCH handbook utilization. This study aimed to analyze factors related to the utilization of MCH handbook by mothers in Indonesia. Cross sectional observational study was conducted from March to May 2018. This study involved mothers with children aged 3 to 72 months old in Surabaya, East Java, Indonesia. Specific population of mothers who had children attending Early Childhood Education and Development (ECED) and Integrated Health Post (IHP) (Indonesia: Pos Pelayanan Terpadu-Posyandu) were included as inclusion criteria. Maternal characteristics, child health status, employment status, and utilization of MCH handbook were recorded through questionnaire. Association between variables then analyzed statistically using Spearman correlation test. As many as 288 participants were enrolled in this study. We found that mothers' participation of Posyandu was positively correlated with MCH handbook utilization (p<0.05). Meanwhile, mother's occupation (p>0.05), mothers' education (p>0.05), and maternal age (p>0.05) were found to be unrelated to the utilization of MCH handbook. Mothers' age, education, and employment were found to be uncorrelated with utilization of MCH handbook. Whereas, mothers' participation in Posyandu was a determinant factor correlated with utilization of MCH handbook.

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