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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 17 Documents
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Search results for , issue "Vol. 59, No. 3" : 17 Documents clear
Front Matter Vol.59 No.3 [9/2023] Indonesiana, Folia Medica
Folia Medica Indonesiana Vol. 59, No. 3
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Back Matter Vol.59 No.3 [9/2023] Indonesiana, Folia Medica
Folia Medica Indonesiana Vol. 59, No. 3
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The Effect of Childhood Obesity on Psychomotor Behavior Khalfani, Muhammad Adrian; Rejeki, Purwo Sri; , Sakina; Fathil, Nur Ezza Fazleen Mohd
Folia Medica Indonesiana Vol. 59, No. 3
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Childhood obesity is a complex problem, and its prevalence among school-age children has been found to have a greater impact on their physical well-being compared to their learning difficulties. In some cases, teachers or schools may not pay enough attention to issues that have the potential to affect or delay the psychomotor development of children. Therefore, this study aimed to provide enhanced comprehension regarding the effect of childhood obesity on psychomotor behavior. This study used a systematic review methodology to synthesize information regarding the effect of obesity on children's health and development. The information and data presented in this study were obtained from several scientific sources accessed through online libraries such as PubMed, ScienceDirect, and the Cochrane Library. A comprehensive search was conducted to identify scholarly publications, which resulted in a total of 815 papers published between 2013 and 2022. The selected papers exclusively consisted of original research articles that primarily focused on investigating the relationship between obesity in children aged 5–14 years and their psychomotor abilities and development outcomes. Following the screening process, five studies were found to meet the specified criteria. The findings of the selected studies revealed a substantial resemblance, specifically the correlation between childhood obesity and poor motor skills. Furthermore, the selected studies discovered that an increase in body fat is commonly associated with a rise in total body weight, or the relative body mass index (BMI), in both adults and children. Some studies demonstrated significant differences in the performance of diverse psychomotor variables according to children's BMI. According to the results of the studies, children with a higher BMI showed inferior performance in motor activities as a result of compromised body control and balance that inhibited the children's movement. This systematic review concludes that obesity has an effect on the psychomotor behavior of children.
Hemoglobin A1c (HbA1c) Levels from the Examination of Different Blood Proportions in K2EDTA Tubes using an Enzymatic Method , Museyaroh; Nabilah, Musholli Himmatun; Werdiningsih, Retno
Folia Medica Indonesiana Vol. 59, No. 3
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Highlights: 1. Research on the effect of blood volume proportion in the examination of HbA1c levels using K2EDTA anticoagulantvhas yet to be widely carried out in Indonesia. 2. The analysis conducted utilizing K2EDTA tubes revealed that the varying proportions of blood samples had no effectvon HbA1c levels. 3. This article highlights the necessity of evaluating the pre-analytical phase (sample preparation) of a laboratory process to improve the accuracy of the results and minimize false high or low results in the HbA1c test. Abstract Hemoglobin A1c (HbA1c) examination is the gold standard for diagnosing and monitoring diabetes mellitus patients. In the examination, the pre-analytical phase has the most considerable error rate at 61%. One of the contributing factors is the use of anticoagulants that do not adhere to established guidelines. Additionally, the incompatibility of the sample volume proportions and the anticoagulants in K2EDTA tubes has been observed in numerous cases. The significance of HbA1c testing, particularly in the prevention of diabetes complications, underscores the need for appropriate procedures to be followed throughout the sampling and pre-analytical phases. This study aimed to determine the effect of differences in the proportion of blood sample volume and anticoagulants in K2EDTA tubes on HbA1c levels. This research was conducted in August–September 2022. The research samples were collected from the staff and students at the Department of Medical Laboratory Technology, Politeknik Kesehatan Kemenkes Surabaya, Surabaya, Indonesia. The blood samples were divided into K2EDTA tubes with varying volumes of 1 mL, 2 mL, 3 mL, and 4 mL. The HbA1c levels were then examined at the Clinical Chemistry Laboratory of Politeknik Kesehatan Kemenkes Surabaya. The data were analyzed using a one-way ANOVA test. The statistical test results (p>0.05) indicated that the proportion of samples containing anticoagulants in the K2EDTA tubes did not have any significant effect on HbA1c levels. In conclusion, it is acceptable to utilize K2EDTA tubes with varying blood sample volumes for the measurement of HbA1c levels.
Physical Activity Levels and Total Food Intake among Preclinical Students at a School of Medicine and Health Sciences Halim, Lydia Esterlita; Tjhay, Francisca; Prastowo, Nawanto Agung; , Vetinly; Widjaja, Nelly Tina
Folia Medica Indonesiana Vol. 59, No. 3
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Highlights: 1. This is the first cross-sectional study in Indonesia that was conducted specifically to find a correlation between physical activity levels and food intake. 2. As lower physical activity was found to be associated with higher food intake, this study suggests that physical activity might be taken into consideration to manipulate one's food consumption Abstract One of the most crucial things a person can do to enhance the well-being of their body is to engage in regular physical activity. However, currently, there are still many people who have low physical activity levels. It is stated that habitual physical activity can affect the sensitivity of food intake regulation. This study aimed to determine the correlation between the total food intake and physical activity of preclinical students. This study was conducted using the cross-sectional method among preclinical students (n=238) in the classes of 2017, 2018, and 2019 at the School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia. Subjects with appetite-manipulating supplements, a diet program, a history of metabolic disease, a history of eating disorders, stress, or trauma were excluded from this study. The physical activity level was evaluated using the Baecke Physical Activity Questionnaire (BPAQ), while the total food intake was evaluated using the three-day food record method. The statistical test applied in this study was the Spearman test, with a significance of p<0.05. There were 22.3% of respondents with a low physical activity level, and there were 9.7% of respondents with a total food intake higher than recommended. The statistical analysis showed a significant negative correlation between physical activity levels and total food intake (p=0.008). In conclusion, there is an association between students' physical activity levels and their total food intake.
Antibiotic-Producing Streptomyces sp. Isolated from the Soil of a Mangrove Ecosystem Retnowati, Wiwin; Mertaniasih, Ni Made; Purwanta, Marijam; Wiqoyah, Nurul; , Atika; Maharani, Sekar; Mahdani, Wilda
Folia Medica Indonesiana Vol. 59, No. 3
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Highlights: 1. The unexplored soil of mangrove ecosystems in Surabaya, Indonesia, has the potential to be home to biodiversity, including Streptomyces sp. that can produce antibiotics. 2. Streptomyces sp. has antibacterial properties against Gram-positive and Gram-negative bacteria, and the duration of incubation plays a critical role in regulating the antibacterial activity. Abstract A mangrove ecosystem in Surabaya, Indonesia, has a high salinity, pH, potassium, phosphorus, and nitrate contents. This ecosystem comprises a mixture of sand, dust, mud, and clay, which has the potential to be a conducive environment for the isolation of Streptomyces. The importance of Streptomyces in biotechnology lies in its ability to produce bioactive secondary metabolites, which represent a valuable reservoir of antibiotics. This research aimed to assess the antibiotic activity exhibited by Streptomyces sp. isolated from the soil of a mangrove ecosystem in Wonorejo, Surabaya, Indonesia. The analysis focused on the potential of Streptomyces sp. to produce antibiotics that work against Gram-positive bacteria (i.e., Staphylococcus aureus ATCC 25923 and Bacillus subtilis) as well as Gram-negative bacteria (i.e., Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Salmonella Typhimurium). The antibacterial activity test was conducted using the modified agar diffusion method. Observations were performed to identify any clear zone formation around the Streptomyces sp. agar colonies with a diameter of 0.8 cm and a height of 3 mm. The clear zone diameter was measured every 24 hours during the 10-day incubation period to assess the diversity of antibacterial activity. The antibacterial profile of Streptomyces sp. exhibited varying levels of activity against different bacterial strains in the tests conducted. The inhibition zone diameters demonstrated the highest levels of activity in Bacillus subtilis (15.9 mm) on day 7, Staphylococcus aureus (27.6 mm) on day 2, Pseudomonas aeruginosa (24.3 mm) on day 7, Escherichia coli (29.2 mm) on day 5, and Salmonella Typhimurium (27.5 mm) on day 7. The results indicated that Streptomyces sp. had inhibitory effects against Gram-positive bacteria as well as Gram-negative bacteria. In conclusion, Streptomyces sp. is a source of biodiversity found in the soil of mangrove ecosystems and has the ability to produce antibiotics.
Toxicity Test on the Combination of Caesalpinia sappan and Zingiber officinale in Rattus norvegicus Induced by Complete Freund's Adjuvant Salma, Nadiah Armadanti; , Tukiran; Sutoyo, Suyatno; Sabila, Fauzia Indah
Folia Medica Indonesiana Vol. 59, No. 3
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Highlights: 1. This study determined the toxic effects of combining Caesalpinia sappan and Zingiber officinale extracts, as people need to be aware of the potential side effects of these common herbal remedies for the treatment of rheumatoid arthritis. 2. The combination of Caesalpinia sappan and Zingiber officinale extracts is efficacious and non-toxic as an antiarthritis treatment, hence, the ingredients can be upgraded to standardized herbal medicines and phytopharmaceuticals. Abstract Sappanwood (Caesalpinia sappan) and red ginger (Zingiber officinale) are plant species that have been studied for their efficacy in treating inflammation related to rheumatoid arthritis. This study aimed to examine the effects of combining sappanwood and red ginger in order to determine the potential toxicity of the herbal extracts in medicine. The toxicity testing was carried out in vivo using 32 Wistar strain male white rats (Rattus norvegicus) grouped into eight groups of four. The rats were injected with complete Freund's adjuvant to induce a chronic inflammatory effect. The eight groups consisted of the negative control group, the positive control group, the normal group, and five treatment groups. This study was conducted by observing the animals for toxic symptoms and death to determine the safety of the extracts and drugs. The observation results were analyzed using a one-way analysis of variance (p<0.05). The analysis results showed that weight gain and relative organ weight among the groups had no significant differences (p>0.05). Microscopic examination of the organ preparations observed under a light microscope revealed no significant changes or adverse effects in rats treated with the extracts or drugs. In conclusion, a combination of sappanwood and red ginger ethanol extracts administered orally has no toxic effect in rats injected with complete Freund's adjuvant.

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