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Made Krisna Adi Jaya
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Gedung Dekanat lantai 1, Fakultas MIPA, Universitas Udayana, Jl Kampus Bukit Jimbaran No 9A, Jimbaran, Badung-Bali.
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Journal Pharmaceutical Science and Application (JPSA)
Published by Universitas Udayana
ISSN : 23017694     EISSN : 23017708     DOI : https://doi.org/10.24843/JPSA.2025.v01.i01
Core Subject : Health, Science, Education, Social, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other
Journal Pharmaceutical Science and Application (JPSA) publishes high-quality original research articles, review articles, and short communications that contribute substantially to the advancement of knowledge in the field of pharmaceutical sciences and their applications. The journal welcomes interdisciplinary work that integrates basic and applied research relevant to drug discovery, development, and clinical use. Areas of interest include, but are not limited to: Pharmaceutical Technology Pharmaceutics Novel Drug Delivery Systems Biopharmaceutics and Pharmacokinetics Pharmaceutical/Medicinal Chemistry Computational Chemistry and Molecular Drug Design Pharmacognosy and Natural Product Research Pharmacology and Toxicology Pharmaceutical Analysis Pharmacy Practice Clinical and Hospital Pharmacy Community Pharmacy Cell Biology and Molecular Pharmacology Genomics, Proteomics, and Pharmacogenomics Bioinformatics and Biotechnology The journal is committed to disseminating impactful findings that enhance pharmaceutical knowledge and promote the development of safe, effective, and accessible therapies.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 82 Documents
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ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT OF RED ANDONG LEAVES (Cordyline fruticosa (L.) A.Chev.) AGAINST Bacillus cereus FNCC-0059 Elisabeth Oriana Jawa La; Ni Putu Prasintia Dewi; Repining Tiyas Sawiji; Ni Ketut Esati; Mahadri Dhrik
Journal Pharmaceutical Science and Application Vol. 8 No. 1 (2026): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2026.v08.i01.p03

Abstract

Introduction: Cordyline fruticosa (L.) A.Chev. (red andong) has long been utilised in traditional ethnopharmacological practices by several indigenous communities, including the Dayak and Tolaki Mekongga tribes. The leaves are reported to contain various bioactive secondary metabolites, including flavonoids, tannins, saponins, and triterpenoids, which are associated with antibacterial activity. Objective: This study aims to identify the phytochemical content and antibacterial activity of the ethanol extract of red andong leaves (Cordyline fruticosa (L.) A. Chev.) against Bacillus cereus. Methods: This laboratory experimental study involved plant identification, sample collection, ethanol maceration extraction, phytochemical screening, and evaluation of antibacterial activity. Antibacterial activity against B. cereus was determined using the agar well diffusion method. The ethanolic leaf extract was tested at concentrations of 30%, 60%, and 90%, with azithromycin 1% serving as the positive control and water for injection as the negative control. Results: Phytochemical screening of red andong leaf extract showed positive results for flavonoids, saponins, tannins, phenols, and triterpenoids. Red andong leaf extract had antibacterial activity against Bacillus cereus at concentrations of 30%, 60%, and 90%. Mann-Whitney analysis showed that all concentrations were significantly different from the negative control (p≤0.05), but there was no significant difference between concentrations. Conclusion: The ethanol extract of red andong leaves positively contained flavonoids, saponins, tannins, phenols, and triterpenoids. Cordyline fruticosa (L.) A.Chev. Leaf extract has antibacterial activity against Bacillus cereus FNCC-0059, with moderate to strong inhibition. Keywords: Cordyline fruticosa (L.) A.Chev.; Bacillus cereus; antibacterial activity; agar well diffusion method; phytochemical screening
Journal Pharmaceutical Science and Application (JPSA)_Table of Content Journal Pharmaceutical Science and Application
Journal Pharmaceutical Science and Application Vol. 8 No. 1 (2026): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Table of Content_Vol. 8 No. 1 (2026): Journal Pharmaceutical Science and Application (JPSA)

Page 9 of 9 | Total Record : 82

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