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Mahardika Darmawan Kusuma Wardana
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journal@umsida.ac.id
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082143483630
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Jl. Mojopahit 666 B Sidoarjo, Jawa Timur 61215
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INDONESIA
Academia Open
ISSN : -     EISSN : 27147444     DOI : 10.21070/acopen.11.2026.12985
Core Subject : Health,
Academia Open is published by Universitas Muhammadiyah Sidoarjo published 2 (two) issues per year (June and December). This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. This journal aims is to provide a place for academics and practitioners to publish original research and review articles. The articles basically contains any topics research or review. Academia Open is available in online version. Language used in this journal is Indonesia or English.
Articles 2,563 Documents
Correlation of Malocclusion, Dental Crowding With Dental Caries and Calculus in Mixed Dentition : Korelasi Antara Maloklusi dan Gigi Berdesakan dengan Karies Gigi dan Karang Gigi pada Masa Pertumbuhan Gigi Campuran Lila Muntadir; Twi Agnita Cevanti; Lambang Bargowo; Nining Dwi Suti Ismawati; Windy Yuliartanti; Wanda Karisma Dian Sari; Rizqi Aulia Kusuma Andini; Marisa Elvi Dayanti; Eka Setyawardana; Reni Puspa Daniati
Academia Open Vol. 11 No. 2 (2026): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.11.2026.15285

Abstract

General Background: Mixed dentition is a transitional stage characterized by dynamic occlusal development, while irregular tooth alignment may create plaque-retentive areas that complicate oral hygiene. Specific Background: Although crowding may facilitate biofilm retention, evidence linking this condition with caries during mixed dentition remains inconsistent. Knowledge Gap: Available evidence regarding crowding as a caries-related factor is limited and heterogeneous, particularly when caries experience in permanent and primary teeth is assessed separately. Aims: This cross-sectional study examined the relationship between crowding and caries status, DMFT, and deft among 30 fourth-grade students aged 10–11 years. Results: Crowding occurred in 83.3% of participants and caries in 60.0%. Fisher’s exact test showed no significant relationship between crowding and caries status (p = 0.066). DMFT did not differ significantly between groups (U = 75.50; p = 0.439), and deft likewise showed no significant difference (U = 85.00; p = 0.171). Novelty: The study provides sample-specific evidence by evaluating crowding against caries status while separately examining permanent and primary tooth caries indices during mixed dentition. Implications: Crowding alone does not sufficiently explain caries experience in this sample. Interpretation requires caution because of the small and imbalanced groups, incomplete crowding-severity data, and cross-sectional design. Highlights: Alignment irregularity was recorded in 83.3% of the sample. Fisher’s exact testing remained above the significance threshold (p = 0.066). DMFT and deft comparisons were nonsignificant (p = 0.439 and p = 0.171). Keywords: Dental Crowding, Dental Caries, Mixed Dentition, DMFT, Deft
Early Hair Regrowth With Adjunctive Secretome Therapy in Severe Patchy Alopecia Areata: Pertumbuhan Rambut Dini dengan Secretome Adjuvan pada Alopecia Areata Berat Zada Febrial Effendy; Anang Silahudin; Dhyah Aksarani Handamar; Shinta Dewi Rahmadhani Soetojo
Academia Open Vol. 11 No. 2 (2026): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.11.2026.15456

Abstract

General Background: Alopecia areata is a non-scarring immune-mediated hair loss disorder with an unpredictable course and frequent relapse. Specific Background: Corticosteroids remain standard treatment for active disease, but responses may be inconsistent when scalp involvement is extensive, while clinical evidence for mesenchymal stem cell-derived secretome remains limited. Knowledge Gap: Reports combining MSC-derived secretome with standard corticosteroid therapy in severe patchy alopecia areata while objectively tracking Severity of Alopecia Tool scores remain scarce. Aims: This case report described the early clinical course of a 23-year-old man with severe patchy alopecia areata and an estimated baseline SALT score of 73 who received intralesional triamcinolone, oral methylprednisolone, topical mometasone, and adjunctive secretome. Results: After one month, hair density increased with visible vellus and early terminal hairs, while the estimated SALT score decreased from 73 to 55, representing approximately 25% less scalp involvement. No new patches, local complications, or reported systemic adverse effects were observed. Novelty: The case provides objectively tracked early SALT changes during a corticosteroid-based multimodal regimen incorporating cell-free secretome. Implications: The findings warrant controlled prospective studies with standardized preparations and longer follow-up because the concurrent treatments prevent attribution of the observed response to secretome alone. Highlights: Estimated scalp-loss scoring declined from 73 to 55 within one month. Vellus and terminal hairs became visible across previously bald scalp regions. No treatment-related local or systemic adverse effects were observed during follow-up. Keywords: Alopecia Areata, Secretome, Intralesional Triamcinolone, Corticosteroids, Regenerative Medicine
Erratum: Profile and Appropriateness of Antibiotic Use Among Outpatients with Respiratory Tract Infections at the Pagantenan Subdistrict Community Health Center Zakaria Zakaria; Lisa Narulita; Sufiyatin Riski Adawiyyah; Akhmad Fathir
Academia Open Vol. 12 No. 1 (2027): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.12.2027.15632

Abstract

This erratum provides corrections to the author information of the article “Profile and Appropriateness of Antibiotic Use Among Outpatients with Respiratory Tract Infections at the Pagantenan Subdistrict Community Health Center,” originally published in Academia Open, Vol. 11 No. 2 (2026), DOI: 10.21070/acopen.11.2026.14738. The correction includes presenting Zakaria as the author name, adding Sufiyatin Riski Adawiyyah to the author list, correcting the spelling of Akhmad Fathir’s name, and completing the authors’ professional credentials, affiliation, and email addresses. These corrections are intended to ensure accurate author attribution and appropriate metadata for citation and indexing. No changes are made to the scientific content, data, results, discussion, or conclusions of the original article. The corrected author information should be used in the article metadata and subsequent citation and indexing records. The original article is available at https://doi.org/10.21070/acopen.11.2026.14738.