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Nelis Hernahadini
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Jurnal Biodiversitas dan Bioteknologi
Published by Universitas Muhammadiyah Bandung
ISSN : -     EISSN : 30891671     DOI : -
Core Subject :
BIODIVERSE: Jurnal Biodiversitas dan Bioteknologi, merupakan salah satu jurnal ilmiah yang diterbitkan oleh Program Studi Bioteknologi yang memuat artikel penelitian dan revew jurnal dalam bidang Biodiversitas dan Bioteknologi (Biodiversitas, Struktur dan Fungsi Sel; Biokimia Sel, Protein dan Enzim, Genetika Terapan dan Molekuler; Genomik dan Proteomik; Mikrobiologi Terapan; Bioproses; Kultur Jaringan, Sel Punca; Bioinformatika; Virologi; serta Bioteknologi Terapan
Arjuna Subject : -
Articles 24 Documents
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Analisis Durasi Tidur, Kualitas Tidur, dan Kesehatan Fisik Mahasiswa Bioteknologi Universitas Muhammadiyah Bandung pada Berbagai Semester: Studi Kasus Tanpa Hubungan Signifikan Nisa Ihsani; Siti Nurbaeti; Neva Afifah Putri Suharja; Viga Indra Kusumawati; Rizki Pajar Nugraha
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 2 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

College students usually experience difficulties and sleep disorders, which would harm their health and can affect their academic performance. This study was conducted to analyze the correlation between sleep duration, sleep quality, and physical health of Biotechnology students at Universitas Muhammadiyah Bandung. The research was carried out using questionnaires. The questionnaire analysis result showed that the average sleep duration of students was 2-4 hours. However, there was no correlation between sleep duration and physical health (p>0.05), as well as between sleep quality and physical health (p>0.05) at every semester levels.
Korelasi antara Konsumsi Makanan Pedas dan Asam dengan Gejala Asam Lambung pada Mahasiswa Universitas Muhammadiyah Bandung Nisa Ihsani; Desti Raflianti; Mahesa Dhiyaa Alkhairan; Nadila Suci Nugraha; Wafa
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 2 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Nowadays, spicy and sour foods are very popular among teenagers, especially among college students. Snacks with spicy and sour flavors are enjoyed by various age groups because some of them offer the distinctive taste of West Java, particularly from the city of Bandung. Excessive consumption of spicy food can lead to health issues, as spicy foods contain capsaicin, which can stimulate pain receptors in the digestive tract. This observational study was carried out by distributing questionnaires containing a set of written questions to gather research data from 176 students at Universitas Muhammadiyah Bandung. This study sought to identify the proportion of preferences for spicy and sour foods. It also examined the relationship between the preference for spicy food and the occurrence of acid reflux symptoms. This research also analyzed the connection between the preference of spicy food and the symptoms of acid reflux. The results showed that a total of 79% of respondents liked spicy food, while the remaining (21%) were not into spicy and sour food (p<0.05). However, the preference for spicy food did not correlate with the occurrence of the acid reflux of the respondents (p>0.05). Meanwhile, 48% of respondents like sour food, while 52% do not like it (p>0.05).
Model Biorekognisi Pengenalan Salmonella typhi Pada Biosensor Elektrokimia Cusiyani Aprillia; Salma Tajki Mulkiyah
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 2 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Typhoid fever is a significant health issue in Indonesia, particularly among children aged 5–14 years, with a prevalence rate of 1.60% of the total population. This disease is caused by Salmonella typhi, a pathogenic bacterium with high virulence and resistance levels. Delayed diagnosis and treatment increase the risk of mortality to 5–6%. Therefore, a sensitive, rapid, and accurate diagnostic tool is urgently needed to detect this bacterium. This research uses a literature review method by analyzing 32 journals that discuss the detection of S. typhi bacteria using biosensors. These journals were obtained from Google, PubMed, and Google Scholar, and selected based on criteria such as year of publication, relevance, scope, journal reputation, and author credibility. Recent scientific articles discussing various bioreceptors, such as antibodies, DNA probes, and aptamers. Electrochemical biosensors were selected due to their advantages in sensitivity, selectivity, cost-efficiency, and on-site detection capabilities. The results indicate that aptamers show the greatest potential as bioreceptors compared to antibodies and DNA probes. Aptamers offer high affinity, stability under extreme conditions, and low production costs. With a sensitivity of up to 10 fM and high selectivity, aptamers are an innovative solution for improving the accuracy and speed of S. typhi detection. In conclusion, electrochemical biosensors based on aptamers represent a promising technology for detecting S. typhi, which is expected to reduce mortality rates from typhoid fever through more effective early diagnosis.
Infeksi HIV : Respon Imun Seluler dan Humoral Selvy Lavia Putri Pricilla; Aflah Afina Nurdin
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 2 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

HIV stands for Human Immunodeficiency Virus, which as the name suggests damages the human immune system. HIV is the virus that causes Acquired Immunodeficiency Syndrome (AIDS). Since the beginning of the HIV epidemic, many studies have shown that HIV infection directly affects the immune system, from both humoral and cellular immunity aspects. The purpose of this journal is to provide information on the mechanisms of humoral and cellular immune responses in HIV infection. HIV infection directly affects the immune system, from both humoral and cellular immunity aspects. Cellular immunity involves T cells in the identification and destruction of pathogens infected with body cells. Cellular components interact and instruct the adaptive immune response. Complementary humoral immunity and mediators between innate and adaptive immune responses can directly neutralize viruses and modulate pathogen elimination. Humoral immunity is immunity with antibody formation by plasma cells derived from B lymphocytes, as a result of cytokines released by activated CD4 lymphocytes.
Review: Peran Protein Virus dalam Host Immune System Evasion Nurhaifa Azzahra; Nazif Muhammad; Wulan Pertiwi
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 2 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

The human body has an immune system that functions to protect the body from pathogens such as bacteria and viruses. This system consists of two types of immunity: non-specific immunity (innate immunity) and specific immunity (adaptive immunity). Non-specific immunity acts quickly using various cells and molecules to combat pathogens, while specific immunity takes longer but is more effective and has the ability to remember pathogens for a faster response in the future. Despite this, many viruses have developed mechanisms to evade detection and elimination by the immune system, known as immune evasion. This evasion is carried out in various ways, including modifications of viral proteins that disrupt immune pathways, such as antigen presentation, interferon signaling, and immune cell functions. This literature review aims to identify the various strategies used by viruses to evade the immune system. The method used is a literature search from various scientific journals such as PubMed, Wiley, and Elsevier. The analysis results show that viruses can avoid PRR detection, inhibit JAK-STAT signaling, and regulate autophagy to survive and replicate within the host body. This study provides an in-depth understanding of the immune evasion mechanisms by viruses, which are a major challenge in the treatment and prevention of infectious diseases. A deep understanding of these immune evasion mechanisms in crucial for developing more effective strategies to fight viral immune evasion, thereby enhancing the effectiveness of therapies and vaccines in the treatment and prevention of infectious diseases
Peran Virus Onkolitik dalam Terapi Kanker: Tinjauan Literatur Tiara Zahira; Mahesa Dhiyaa Alkhairan; Rica Handayati; Wulan Pertiwi
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 2 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Cancer is one of the leading causes of death in the world and a major challenge in the medical world. This disease is caused by uncontrolled cell growth and can damage healthy tissue. Conventional therapy still has limitations, so new approaches are needed such as oncolytic virus-based therapy. This study aims to present a review of the use of oncolytic viruses in cancer therapy, including the mechanism of action, effectiveness, and challenges faced. The method used is an online literature review with a focus on various aspects of oncolytic viruses. The results show that oncolytic viruses can destroy cancer cells in a specific way, while triggering the body's immune response. In addition, this therapy shows better effectiveness when combined with chemotherapy. The use of oncolytic viruses as cancer therapy offers promising potential, although there are still challenges in terms of virus spread and patient response. Further development is needed to maximize the effectiveness of this therapy.
Strategi Pencegahan Influenza Terhadap Resistensi dan Efektivitas Antiviral : Kajian Literatur Aulia Putri Salsabila; Neva Afifah Putri Suharja; Nurul Fadhillah; Wulan Pertiwi
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 2 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Influenza is a viral infection that can cause serious complications and spread rapidly. Antivirals such as oseltamivir, zanamivir, peramivir and baloxavir are effective at reducing the duration of illness if given within the first 48 hours. However, viral mutations can lead to resistance to antivirals, decreasing the effectiveness of treatment. This review analyzes antiviral resistance and effectiveness based on a literature review from various sources. Results show that resistance to oseltamivir and amantadine is a major challenge, and antiviral effectiveness is affected by the timing of administration, patient condition, and viral mutations. Several strategies, including antiviral combinations, new drug development, herbal plants, and vaccination, were developed to overcome resistance, but none have been fully effective. Monitoring viral resistance and developing adaptive treatment strategies are needed to improve influenza control.
Perbandingan Efektivitas Mikroba Hasil Rekayasa Genetik dan Mikroba Alami dalam Bioremediasi Polutan Lingkungan : kajian literatur: Comparison of Effectiveness of Genetically Engineered Microbes and Natural Microbes in Bioremediation of Environmental Pollutants: a literature review Neva Afifah Putri Suharja; Fadly Hidayaturochman; Tsabitna Amalia Ihsani
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 1 (2025): Vol 2 No 1 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Environmental pollution is becoming an increasingly pressing issue, threatening human health, ecosystems and the sustainability of natural resources. Genetically modified microbes are designed to have a higher degradation ability of harmful compounds compared to natural microbes, thereby increasing the efficiency of enzymes involved in this process. The objectives of this research include; analyzing the potential of genetically engineered microbes in degrading environmental pollutants, evaluating the efficiency and resistance of genetically engineered microbes and natural microbes in degrading environmental pollutants, examining the implications of using genetically modified microbes on environmental sustainability, ecosystem safety, and analyzing the GEO microbial control system post-bioremediation. The method of writing this literature review uses online-based literature searches with sources from Google Scholar, Pubmed and Sciencedirect. GEO microbes have the potential to degrade environmental pollutants and are superior to natural microbes. The advantages of GEO microbes in degrading environmental pollutants such as specificity, high efficiency, and environmentally friendly. GEO microbes are proven to be effective in degrading various pollutants. GEO microbes released into the environment to degrade pollutants are at risk of disrupting the balance of the environmental ecosystem. The population of GEO bacteria in the environment can be suppressed using composting and reducing the population of GEO bacteria.
Green Nanotechnology Sintesis Nanopartikel (NP) dari Tanaman untuk Bioremediasi Logam Berat Hg, Cr, dan Pb Kajian Literatur Hasna Labib Lathifah; Adilla Syahsiyatun Najah; Marsya Naranissa Puteri Santoso
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 2 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Abstract

Heavy metals are toxic pollutants that cause environmental pollution. Heavy metals that enter the environment cannot be degraded either biologically or chemically and can remain in the environment for a long time. Bioremediation is a technique to protect the environment from contaminants using biological agents. One of the Green Nanotechnology technologies can contribute to bioremediation. Therefore, the purpose of this literature review is to find out the concept of green nanotechnology bioremediation by synthesizing nanoparticles from plants for bioremediation of heavy waste hg, cr, Pb. the literature review method used is an online-based literature review with sources derived from Google Scholar, Pubmed and Sciencedirect. Plant extracts were obtained in both aqueous and non-aqueous media using hot solvents or cold extraction methods. The plant extracts were then filtered and a solution suitable for the nanoparticles to be synthesized was added. Nanotechnology bioremediation has high potential to be used in surface water, groundwater, and wastewater treatment technologies to filter on a nanoscale so that water is able to pass but large materials such as bacteria and viruses and their products (toxins) will be filtered out on nanoparticles. In addition, catalysts and filters can be designed to produce high adsorption strength so that they can absorb heavy metal ions.
Potensi Bioremediasi Minyak Diesel dengan Menggunakan Bakteri Bacillus subtilis: Kajian Literatur Aghniya Nur Rizka Fadila; Muhammad Rafi Pratama Shidiq; Triani Nur Fitri
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 1 (2025): Vol 2 No 1 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Diesel is a pollutant fossil fuel that is used significantly. Its carcinogenic nature is a by-product of petroleum processing, if diesel spills or pollutants are diluted, it will have a dangerous environmental lethal effect. Bacillus subtilis is a hydrocarbonoclastic bacterium capable of secreting hydroxylase enzymes, which can degrade hydrocarbons and their derivatives into simpler compounds. So the purpose of this literature review is to determine the potential effectiveness of B. subtilis bacteria in bioremediating Diesel Oil. The method used is a literature review sourced from official websites and the like. Bacteria B. subtilis  has the ability to remediate diesel with enzymes produced, suitable bioremediation techniques namely bioaccumulation, biostimulation, and bioavability that meet the success factors. The results showed that B. subtilis  was able to degrade diesel to 12.8% diesel content within 12 days. With this ability, this bacterium is a bioremidiation agent that can be used to remediate diesel.

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