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Contact Name
Winni Maharani
Contact Email
winni@unisba.ac.id
Phone
+6285220013654
Journal Mail Official
gmhc@unisba.ac.id
Editorial Address
Jl. Hariangbanga No. 2, Kota Bandung, 40132, West Java, Indonesia
Location
Kota bandung,
Jawa barat
INDONESIA
Global Medical and Health Communication
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc.v13i2
Core Subject :
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, health communication, health promotion, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Arjuna Subject : -
Articles 35 Documents
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Profiling for Quinolinone Alkaloids and Phenolic Metabolites in a Bioactive Fraction of Indonesian Yacon (Smallanthus sonchifolius) Tuber Extract Eka Hendryanny; Widayanti; Lelly Yuniarti
Global Medical & Health Communication (GMHC) Vol. 13 No. 3 (2025): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i3.8796

Abstract

Yacon (Smallanthus sonchifolius) is a functional tuber rich in fructooligosaccharides, phenolic compounds, and diverse secondary metabolites with potential health-promoting properties. Despite its increasing use, the comprehensive characterization of its bioactive constituents, particularly those derived from plants cultivated in Indonesia, remains limited. This study aims to identify and characterize the major bioactive components of ethanolic yacon tuber extract using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This descriptive, exploratory investigation of natural product phytochemistry was conducted from June to July 2025—fresh tubers were collected from Lembang, West Bandung. The samples were subjected to ethanol maceration, and LC-MS/MS analysis was performed on a bioactive fraction (Rf 0.52) obtained from preliminary thin-layer chromatography (TLC) fractionation of the crude ethanolic extract, using positive electrospray ionization and gradient elution. Compound annotation was performed using UNIFI software. LC–MS/MS profiling revealed 15 predominant secondary metabolites, with retention times ranging from 5.41 to 13.18 minutes and mass-to-charge (m/z) ratios of 255.35–459.48. Early-retention peaks comprised polar constituents, such as sucrose and nicotianamine, a metal-chelating amino acid known to enhance iron bioavailability. Mid-retention peaks included phenolic acids and flavonoids, notably chlorogenic acid and jaceosidin. High-retention peaks were dominated by hydrophobic alkaloids, with 4,7,8-trimethyl-3-(3-methylbut-2-enyl)-1H-quinolin-2-one identified as the most abundant compound (56.42%), followed by senecionine (9.36%) and nonadecan-2-amine (6.75%). In conclusion, West Bandung yacon tubers contain a diverse spectrum of alkaloids, flavonoids, and phenolic derivatives that may contribute to their pharmacological potential. The results provide an essential phytochemical foundation for future studies evaluating bioactivity and toxicological assessment using targeted in vitro and in vivo approaches.
Meropenem Use for Bacterial Infection at a Hospital in Bandung City Winni Maharani; Usep Abdullah Husin; Syahrir Zein Rumatumia; Tresna Ridha Nurramadhani; Lia Marlia Kurniawati; Djatnika Setiabudi
Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i1.8874

Abstract

Meropenem is a beta-lactam antimicrobial agent used to treat broad-spectrum bacterial infections and is classified as a reserve antibiotic. The Antimicrobial Resistance Control Program (PPRA) at the hospital monitors the use of meropenem to ensure it is used appropriately and in accordance with antimicrobial stewardship principles. This study aims to determine the preliminary pattern of meropenem antibiotic use at the hospital, Bandung, during 2019–2020. It is an observational descriptive study using secondary medical record data with a total sampling method. A total of 182 study subjects were all patients treated with meropenem from various departments, and the diagnoses met the criteria for culture results. Data analysis included the distribution proportion of the observed variables. This study shows that the pattern of meropenem use over two years is characteristic of patient age with the most similar patterns in the age categories under 0–10 years, 51–60 years, and 61–70 years (21–26%), however, there were differences in gender in 2019, female patients were more numerous than male patients, while in 2020 were the opposite. Other results show similar diagnostic patterns in both years, with the most common diagnoses being respiratory tract infections, which continued to increase in the following years (27% and 35%). Conversely, the majority of culture results in the two years were negative (58% and 72%). The possibilities here relate to specimen preparation or to prior antimicrobial use before hospital admission. In conclusion, the pattern of meropenem antibiotic use at the hospital is similar in characteristics, diagnostics, and culture results. The PPRA Committee is expected to improve the policy on meropenem use in accordance with government regulations and prevent antimicrobial resistance.
Family Health Outcomes during Economic Crises: the Role of Household Nutrition Coping Strategies I Nyoman Adiyasa; Aliah Bagus Purwakania Hasan
Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i1.8936

Abstract

The prolonged economic downturn at both national and household levels has significantly disrupted food access, altered dietary patterns, and increased the risk of nutrition-related health problems. This study aimed to identify household nutrition coping strategies during economic hardship and examine their association with family health outcomes, particularly among vulnerable groups such as women and young children. A cross-sectional survey was conducted from February to April 2025 involving 210 households in Denpasar (Bali) and Mataram (West Nusa Tenggara). A purposive sampling technique was applied to select households experiencing income decline and changes in food consumption. Data were collected using a structured questionnaire assessing food security status, dietary patterns, and coping behaviors, complemented by basic health indicators. Data were analyzed using descriptive statistics, chi-square tests, and Spearman correlation analysis. The results indicate that 68% of households reduced meal portions, 63% substituted nutritious foods with cheaper alternatives, and 47% reduced meal frequency. A significant association was found between coping strategy categories and household health symptoms (p<0.05). Furthermore, a moderate positive correlation was observed between coping intensity and family health symptom scores (r=0.482, p<0.01), indicating that households employing more coping strategies tended to report higher levels of health-related complaints. Approximately 36% of households reported weight loss among children, and 29% reported decreased appetite. These findings suggest that while coping strategies serve as short-term adaptive mechanisms, their frequent use is associated with declining dietary quality and increased health vulnerability among family members. Strengthening community-based nutrition resilience programs and integrating responsive social protection policies are essential to mitigate the long-term health impacts of economic crises. This study provides empirical evidence on the relationship between coping behavior and household health outcomes in vulnerable urban and semi-urban populations.
The Relationship between Nutritional Status and Menstrual Blood Volume among Adolescent Girls at A Boarding School Qonita Luthfiah; Eva Rianti Indrasari; Yafma Femin Helta Heriady; Mirasari Putri
Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i1.8998

Abstract

Menstruation is an essential physiological process in adolescent girls. Reflecting not only reproductive health but also overall health status. Menstrual disorders, particularly heavy menstrual bleeding (menorrhagia), are common among adolescents, with a prevalence of approximately 12–37%. Nutritional status plays a key role in menstrual health. In adolescents with overnutrition, excess body fat can increase estrogen production, which may subsequently affect the menstrual cycle, including the volume of menstrual blood. In boarding school settings, where students live under structured schedules and share dietary patterns, nutritional imbalances are common and may disrupt menstrual patterns. This study aimed to determine the relationship between nutritional status and menstrual blood volume among adolescent girls at a boarding school in Bogor, West Java,  Indonesia, in 2025. It was an observational analytic study with a cross-sectional design involving 85 adolescent girls aged 15–17 years, selected through stratified random sampling according to predefined inclusion and exclusion criteria. Primary data were obtained from menstrual pictogram forms and measurements of body mass index (BMI) and waist circumference. Data were analyzed using univariate and bivariate analyses with the chi-square test. Among the 85 participants, 35 experienced menorrhagia, including all 15 who were classified as overnutrition based on BMI, and 11 participants with increased waist circumference. Fisher’s Exact tests for both BMI and waist circumference against menstrual blood volume yielded p-values <0.001 (p<0.005), indicating a highly significant association. In conclusion, higher BMI and greater waist circumference were strongly associated with increased menstrual blood volume among adolescent girls at a boarding school in Bogor. Nutritional balance and weight control are essential to support healthy menstrual patterns in this population.
Association of Lubricants, Foreplay, and Communication with Lower Dyspareunia Pain among Perimenopausal Women Karwati Karwati; Damai Yanti; Sri Maryati; Rochmawati Rochmawati
Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i1.9030

Abstract

Dyspareunia, or pain during sexual intercourse, is common among perimenopausal women, negatively affecting their quality of life, sexual satisfaction, and relationships. Limited observational data exists on non-pharmacological self-management strategies for pain relief, particularly in Indonesia. This study examines the associations between three self-management strategies—vaginal lubricants, enhanced foreplay, and couple communication—and the reduction of dyspareunia pain in Indonesian perimenopausal women. A cross-sectional study involving 63 women (aged 40–55) with dyspareunia who had used at least one self-management strategy for at least four weeks was conducted at Puskesmas Cimahi Utara, Cimahi, Indonesia, from January 2024 to June 2024. Participants were divided into four groups: lubricants (n=14), foreplay (n=30), communication (n=8), and combined approaches (n=11). Pain intensity was assessed using the Numerical Pain Rating Scale (NPRS). Pre-strategy scores were obtained retrospectively, and post-strategy scores reflected current pain levels. Welch ANOVA and Games-Howell post-hoc tests analyzed mean pain reduction across groups. Significant differences in pain reduction were found among the groups (F(3.59)=24.36, p<0.001, η2=0.553). Lubricants showed the greatest reduction in pain (mean=1.86±0.95 points; 95% CI=1.30–2.41), significantly more than communication (p=0.0295, Cohen's d=0.68) and approaching significance compared to foreplay (p=0.0542, Cohen's d=0.68). All groups reported statistically significant pain reductions. In conclusion, vaginal lubricant use led to the greatest reduction in self-management strategies for dyspareunia pain among perimenopausal women in Indonesia, outperforming enhanced and foreplay couple communication strategies.

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