Global Medical and Health Communication
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, health communication, health promotion, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Articles
35 Documents
<![CDATA[Changes in WHO Z-scores by Gender in Stunting Children of Cipamokolan Public Health Center (2023–2025) ]]>
<![CDATA[Fajar Awalia Yulianto]]>;
<![CDATA[Diany Maedasari]]>;
<![CDATA[Diana Endah Nurul Rachman]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v14i1.7730
<![CDATA[Indonesia’s stunting prevalence exceeds the World Health Organization's threshold of 20%. While nutritional interventions account for 30% of the reduction in stunting, there is no conclusive evidence linking gender directly to stunting outcomes. In 2023, Bandung Regency reported the highest stunting prevalence in West Java Province. This study aimed to analyze the differences in stunting outcomes between boys and girls at a public health center (Cipamokolan) in Bandung Regency. We employed a retrospective cohort design to assess changes in Z-scores (height/length-for-age status) among male and female children aged 0 to 59 months over a 2-year follow-up period, using Cox regression. The study included 153 stunted children, with a majority being males (65.4%). During follow-up, only 7.8% of the children showed an increase in their Z-scores (catch-up), while most (79.1%) maintained their stature. Unfortunately, 13.1% of the children experienced a decline in their Z-scores compared to previous examinations. The hazard ratio (HR) for sex and decreased Z-scores was 1.19 (95% CI=0.46–3.11), indicating no significant difference in worsening stunting cases between boys and girls. Stunting intervention strategies should be implemented equally for all children, regardless of gender, with special attention to treatment management. The lack of improvement or decrease in Z-scores over 2 years indicates a poor outcome from the interventions and requires urgent attention.]]>
<![CDATA[Effect of Propolis on Inhibiting the Proliferation and Migration of T47D Breast Cancer Cell Lines ]]>
<![CDATA[Oeij Anindita Adhika]]>;
<![CDATA[Adelina Khristiani Rahayu]]>;
<![CDATA[Timothy Jonathan]]>;
<![CDATA[Julia Windi Gunadi]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 2 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i2.7732
<![CDATA[In Indonesia, breast cancer was the cancer with the highest number of cases in 2020, reaching 16.6% of all cancer cases and ranking first among all types of cancer in women. Standard cancer treatments were reported to have side effects on patients; therefore, innovation in breast cancer treatment using natural compounds must continue to be carried out, one of which is propolis. Propolis has been reported to bind to the epidermal growth factor receptor, thereby inhibiting the migration and proliferation of cancer cells. This study aims to examine the effect of propolis treatment on the viability and migration of T47D breast cancer cell lines. This study was conducted at the Molecular Biomedical Research Laboratory, Universitas Kristen Maranatha, Bandung, from May to July 2025. Propolis was extracted using ethanol maceration. Cell cytotoxicity and viability were analyzed using the MTT assay, and migration was assessed using the scratch assay after 24 and 48 hours of treatment. We analyzed the expression levels of SRY-box transcription factor 4 (SOX4) and rho-associated coiled-coil containing protein kinase 1 (ROCK1) as markers of proliferation and migration using RT-qPCR. The propolis concentration used in this study was 40 μg/ml, and each treatment was analyzed in triplicate. Results showed that propolis exhibits high cytotoxic activity, which can inhibit the viability of T47D cell lines. The viability of T47D cell lines decreased by 72% after 24 hours of treatment and further reduced to 29.3% after 48 hours of treatment. The results also showed that the migration of T47D cell lines was inhibited (−27%) after treatment with 40 μg/ml propolis, compared to negative controls (53.3%). This study concluded that propolis treatment affected the viability and migration of the T47D breast cancer cell line.]]>
<![CDATA[Eating Habits and Risk Factors for Diabetes Mellitus in Adulthood in Kotamobagu City ]]>
<![CDATA[Meildy Esthevanus Pascoal]]>;
<![CDATA[Ana Barnetje Montol]]>;
<![CDATA[Kevin Giovani Pascoal]]>;
<![CDATA[Ingland J. Kamasih]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v14i1.7853
<![CDATA[Diabetes mellitus is a serious global public health problem and is increasingly common in developing countries like Indonesia. Dietary habits and risk factors are considered predictors of type 2 diabetes mellitus (T2DM). This study aims to analyze dietary habits and risk factors in adults with T2DM. This study used a descriptive design. A cross-sectional survey of an adult population aged 30–65 years in the working area of the Gogagoman Community Health Center in Kotamobagu City was conducted in April–June 2025. A nonprobability sampling technique was used to select respondents sequentially until 100 met the inclusion criteria. The analysis included univariate analyses, a bivariate Spearman test, and a multivariate multiple linear regression. The research instrument used a semi-quantitative food frequency questionnaire and the Finnish Diabetes Risk Score (FINDRISC). The data from 100 respondents were normally distributed, with a Kolmogorov-Smirnov p-value of 0.102 (p>0.05). The Spearman test showed that age, BMI, waist circumference, physical activity, fruit and vegetable consumption, history of high blood pressure medication use, family history of diabetes mellitus, and eating habits were statistically significant (p<0.05). In contrast, gender was not significant (p>0.05). Meanwhile, the results of a multiple linear regression analysis showed a correlation coefficient (R) of 0.868 and an R2 of 0.754, indicating that 75.4% of the risk variables for T2DM were associated with the occurrence of diabetes mellitus. The FINDRISC score showed that 19% had low risk, 61% had moderate risk, and 20% had high risk. In conclusion, lifestyle behavior plays an important role in the prevention and management of T2DM. Consuming balanced nutrition by improving diet quality is the primary determinant, with unhealthy eating patterns associated with an increased risk of T2DM.]]>
<![CDATA[Glomerular-Bowman’s Space Correlation in Obese Rats Treated with Citrus amblycarpa Extract ]]>
<![CDATA[Lena Rosida]]>;
<![CDATA[Roselina Panghiyangani]]>;
<![CDATA[Maria Ulfah]]>;
<![CDATA[Dewi Indah Noviana Pratiwi]]>;
<![CDATA[Siti Wasilah]]>;
<![CDATA[Ika Kustiyah Oktaviyanti]]>;
<![CDATA[Juliyatin Putri Utami]]>;
<![CDATA[Rizki Aprian]]>;
<![CDATA[Andi Muthia Azizah Tenri Bali]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v14i1.7865
<![CDATA[Obesity induces pro-inflammatory fat accumulation that impairs renal function, causing structural damage to the glomerulus and Bowman’s capsule. The anti-inflammatory properties of Citrus amblycarpa Hassk peel extract indicate its potential therapeutic role for these renal disorders. This study aimed to investigate the correlation between histological alterations in glomerular diameter and Bowman’s capsule width in high-fat diet-treated rats. The study used a post test control group. We divided rats into 6 groups: the normal diet (ND) group, the high-fat diet (HFD) group with orlistat, and groups receiving various doses of Citrus amblycarpa Hassk. Peels extract 200, 300, and 400 mg/kgBW. Hematoxylin and eosin (HE) stain was used for renal histological preparations. Glomerular diameter and Bowman’s capsule width were measured using a light microscope equipped with Optilab Viewer software (five microscopic fields). Glomerulus diameter was averaged from two outer-edge measurements, while Bowman’s capsule width was recorded at its widest point. Data were analyzed using Pearson’s correlation test to assess variable relationships. The mean glomerular (µm) of K1 = 89.99±5.68, K2 = 97.56±4.03, K3 = 89.99±3.91, K4 = 90.80±3.88, K5 = 86.09±4.22, K6 = 82.89±2.50 and mean Bowman’s capsule width (µm) K1 = 14.18±4.27, K2 = 9.98±2.24, K3 = 10.12±0.58, K4 = 8.87±2.85, K5 = 14.87±6.42, K6 = 15.39±4.21. The results demonstrated a significant negative correlation between increased glomerular diameter and reduced Bowman's capsule width in all experimental groups (p=0.018, r=−0.430), suggesting that glomerular enlargement is linked to structural shrinkage of the Bowman's capsule. In conclusion, a significant correlation exists between glomerular diameter changes and Bowman’s capsule width in high-fat diet rats treated with Citrus amblycarpa Hassk peel extract.]]>
<![CDATA[The Effect of Mindfulness-based Intervention on Reducing Childhood Trauma Symptoms ]]>
<![CDATA[Dwi Heppy Rochmawati]]>;
<![CDATA[Wigyo Susanto]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 3 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i3.7923
<![CDATA[Childhood trauma is a complex mental health issue with long-term psychological and neurobiological consequences. This study aims to analyze the effect of a mindfulness-based intervention on five dimensions of childhood trauma: emotional abuse, physical abuse, sexual abuse, emotional neglect, and physical neglect. A quantitative quasi-experimental design with a pre-posttest approach was employed, involving 174 young adults aged 18–25 years, conducted at the Faculty of Nursing, Universitas Islam Sultan Agung, Semarang, in June 2025. Childhood trauma symptoms were measured using the validated Childhood Trauma Questionnaire, while the intervention was delivered using an 8-week mindfulness-based stress reduction (MBSR) protocol modified with a trauma-informed framework. Data were analyzed using the Wilcoxon signed-rank test to assess differences in trauma scores before and after the intervention. The results revealed highly significant reductions in emotional abuse, physical abuse, and emotional neglect (p=0.000), as well as a significant reduction of sexual abuse (p=0.034). However, physical neglect did not show a significant change (p=0.166). The study concludes that mindfulness is effective in reducing the psychological impacts of childhood trauma through mechanisms of emotional regulation and enhanced interoceptive awareness. However, its effectiveness varies depending on the trauma subtype. This research contributes to the development of evidence-based trauma interventions and supports the integration of mindfulness within mental health care systems.]]>
<![CDATA[Spatial Distribution of Stunting Incidence in the Highland Area of Tangse Subdistrict, Pidie Regency ]]>
<![CDATA[Fitria Fitria]]>;
<![CDATA[Frisca Fazira]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v14i1.7966
<![CDATA[Stunting is a chronic nutritional issue and serves as a key indicator for assessing child health. Tangse Subdistrict, located in a highland area of Pidie Regency, shows a concerning prevalence of stunting among children. This study analyzed the spatial distribution of stunting cases in Tangse using GIS-based mapping technology. It was a descriptive observational study that utilized secondary data from the Tangse Health Center and was conducted from May to June 2025. The number of stunting cases per village was analyzed and mapped using ArcGIS (ArcMap v10.8) to visualize the spatial distribution by gender and age group. Stunting was found in twenty out of the twenty-eight villages in Tangse, with the highest incidence occurring in Gampong Pulo Baro at 10%. Furthermore, the prevalence was higher among boys (58%) than girls (42%). The age group most affected by stunting was children aged 12 to 23 months. The widespread occurrence of stunting across most villages may be linked to geographical barriers, limited access to health services, and differences in socio-economic and nutritional practices prevalent in highland areas. This study concludes that ArcGIS-based spatial analysis is effective in identifying high-risk areas and distribution patterns of stunting, which can support more targeted and evidence-based interventions at the community level. Further analysis of region-specific risk factors is needed to enhance targeted interventions in Tangse.]]>
<![CDATA[Arcangelisia flava L. Merr. Aqueous Extract Potential as a Xanthine Oxidase Inhibitor ]]>
<![CDATA[Fatmawati]]>;
<![CDATA[Subandrate]]>;
<![CDATA[Rini Yana]]>;
<![CDATA[Maharani Puspita Sari HS]]>;
<![CDATA[Nadia Permata Sari]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 3 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i3.7968
<![CDATA[Arcangelisia flava L. Merr. contains several secondary metabolites, including berberine and palmatine, which are known to have potential as inhibitors of xanthine oxidase (XO). XO is an enzyme involved in purine metabolism, catalyzing the oxidation of hypoxanthine to xanthine and then xanthine to uric acid. The community uses the stems and leaves of A. flava to maintain health by brewing them in hot water. The potential of this plant to inhibit XO using an aqueous solvent has never been studied. This study aims to assess the xanthine oxidase inhibitory activity of water extracts derived from the stems and leaves of A. flava. The study design was an in vitro experimental study conducted in the Basic Medical Chemistry Laboratory of Universitas Sriwijaya from September to December 2023. The aqueous extract of stems and leaves from A. flava was tested using an in vitro xanthine oxidase inhibitory assay, as observed through a decrease in uric acid levels via UV absorption. The stem extract exhibited stronger XO inhibition (IC50=21.15 μg/ml, 95% CI=19.87–22.51) compared with the leaf extract (IC50=68.42 μg/ml, 95% CI=61.35–76.28). The inhibitory activity of the stem extract approached that of allopurinol (IC50=16.78 μg/ml, 95% CI=15.62–18.02). In conclusion, the aqueous stem extract of A. flava demonstrates significantly XO inhibitory activity than the aqueous leaf extract.]]>
<![CDATA[Comparative Analysis of Length of Stay and Cost-effectiveness in Typhoid Patients Treated with Cephalosporins and Fluoroquinolones ]]>
<![CDATA[Yudith Yunia Kusmala]]>;
<![CDATA[Melly Safitri Indriani]]>;
<![CDATA[Desy Linasari]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 2 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i2.7993
<![CDATA[Typhoid fever is an infectious disease caused by the bacterium Salmonella typhi (S. typhi). Hospitals often experience financial losses in treating typhoid fever patients, as the costs exceed the satisfaction provided by the National Health Insurance (Jaminan Kesehatan Nasional, JKN), administered by the Social Security Agency for Health (Badan Penyelenggara Jaminan Sosial, BPJS Kesehatan). This study aimed to evaluate treatment duration and the cost-effectiveness of cephalosporins (ceftriaxone) versus fluoroquinolones (levofloxacin) therapy in adult patients with typhoid fever. This research employs an observational, analytical, cross-sectional design. The data consist of secondary data obtained from the medical records of patients diagnosed with typhoid fever between January 1, 2022, and December 31, 2022, in the adult inpatient ward at Dustira Military Hospital in Cimahi. The study included a total of 162 individuals who met the specified inclusion criteria. We employed the Mann-Whitney test to evaluate the data. The study found that patients with typhoid fever treated with fluoroquinolone antibiotics had a shorter average length of stay (ALOS) of 3.69±0.86 days compared to those treated with cephalosporin antibiotics, whose ALOS was 4.35±1.15 days, with a p-value of 0.000. The difference in ALOS between the two groups was statistically significant. The average total cost for patients who received fluoroquinolone antibiotics was lower (IDR 2,273,213.01) compared to patients who received cephalosporin antibiotics (IDR 2,524,729.11), with a p-value of 0.000. This study concluded that fluoroquinolone therapy is more effective than cephalosporins in reducing the duration of hospitalization among patients with typhoid fever. Accordingly, intravenous fluoroquinolones may be considered as a treatment option to help shorten hospital stay.]]>
<![CDATA[Gender and Age: Do They Play a Role in Medical Faculty Students' Perceptions of the Learning Environment Using the DREEM Instrument? ]]>
<![CDATA[Rika Nilapsari]]>;
<![CDATA[Mia Kusmiati]]>;
<![CDATA[Annisa Rahmah Furqaani]]>;
<![CDATA[Miranti Kania Dewi]]>;
<![CDATA[Rahma Reza Zakiyah]]>;
<![CDATA[Mudzakkir Rayyis]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 3 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i3.7999
<![CDATA[Evaluation and measurement of the learning environment can help improve the quality of education, including by assessing students' perceptions of it. Various internal and external factors will influence students' assessment of the learning environment. One instrument for measuring students' perceptions of the learning environment is the Dundee Ready Education Environment Measure (DREEM). This study aims to analyze the effects of gender and age on students' perceptions of the learning environment at the Faculty of Medicine in Bandung. This study uses primary data collected using the DREEM instrument to examine students' perceptions of the learning environment at the Faculty of Medicine. The subjects of this study were 437 students in the academic phase of the Faculty of Medicine. The research subjects were selected by random sampling. The average score per DREEM domain was then analysed using the Mann-Whitney test because the data were not normally distributed. The results showed that the average scores of female and male students were not significantly different across the DREEM domains (p>0.05). The average score for students aged >20 years was considerably lower in the learning process and lecturer domain than for students aged ≤20 years (p<0.05). In conclusion, age influences students' perceptions of the learning environment at the Faculty of Medicine, while gender does not.]]>
<![CDATA[Determinant Factors of Safety and Health Behavior in Students: A Systematic Review ]]>
<![CDATA[Eka Rosanti]]>;
<![CDATA[Wiwik Eko Pertiwi]]>;
<![CDATA[Sri Achadi Nugraheni]]>
<![CDATA[ Global Medical & Health Communication (GMHC) Vol. 13 No. 3 (2025): Accredited Sinta 2 ]]>
Publisher : <![CDATA[UPT Publikasi Ilmiah Universitas Islam Bandung ]]>
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DOI: 10.29313/gmhc.v13i3.8044
<![CDATA[Schools as educational institutions need to create safe and healthy learning spaces for teachers and students. Currently, many articles discuss student safety and healthy behavior, recognizing that schools are vulnerable to risk factors, hazards, and disasters. This study aims to identify and analyze the determinants of students' safety and health behavior from 2020 to 2024. The systematic literature review method was used to identify articles with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) approach to obtain 23 articles from 4 databases, that are Scopus, Science Direct, Proquest, and PubMed with inclusion criteria are journals published in January 2020–October 2024, in English, open access, and focused on occupational health and safety behavioral factors in students. Four themes, each comprising 14 indicators, were identified as determinants of students' safety and health behavior. The discussion fluctuates each year, involving most countries, and the majority discuss university education. The highest indicator is training (T) with eight articles, followed by technology (Te) with seven articles. This study found that the safety and healthy behavior of students when viewed from the socio-ecological model is grouped into individual (5), interpersonal (1), institutional (4), community (2), and policies macro environment (2). According to Lawrence W. Green's behavioral theory, predisposing factors accounted for 36% (5), supporting factors for 57% (8), and reinforcing factors for 7% (1). Student safety and health behavior are influenced by training, psychological models, and school community support. These findings highlight the need for continuous training and a strong safety culture as the basis for evidence-based educational policies. The conclusion of this systematic literature review is expected to serve as input for policymakers in developing strategic and practical guidelines for safety and health programs in educational units.]]>
