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INDONESIA
Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
Arjuna Subject : -
Articles 15 Documents
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Search results for , issue "Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)" : 15 Documents clear
MACROSCOPICS AND MICROSCOPICS FEATURE OF WITAR RATS LIVER AFTER IMMERSION IN GRADUAL CONCENTRATION OF RANDU HONEY Putri Ariani Kusuma; Tuntas Dhanardhono; Saebani Saebani; Ratna Damma Purnawati; Hermawan Istiadi
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30045

Abstract

Background Formaldeyde is main substance used for organ embalming and even for foods preservations. However, long and high exposure of formaldeyhde lead to various organs irritations. Honey is well-known for its natural preservative activity expected to be the soultion for the problem so there is safe alternative for organ preservations.Aim Observation and examintaion the difference of macroscopic and microscopics feature of Wistar rats liver after immersion of formaldehyde and randu honey.Methods Experimental with post-test only control group design using 24 male Wistar rats as sample, randomly divided into 4 groups consist of: Group C (preserved with 10% formaldehyde solutions), P1 (preserved with 10% randu honey solutions), P2 (preserved with 20% randu honey solutions) and P3 (preserved with 30% randu honey solutions). The sampels were preserved for 24 hours then macroscopic (smell,color and size) and microscopic study with Hematoxylin-Eosin (HE) stain  using 400x observation performed. Manja Roenigk score were used to accessed the degree of live microsopic damage.Results There are normal cells, mild damage, moderate damage and severe damage respectively in the group C: 36%,47%,17%,0% ; P1: 0%,27%,46%,27% ; P2: 0%,77%,17%,6% ; P3: 47%,33%,17%,3%. Kruskal-Wallis test showed significant results with p=0.000. With Mann-Whitney test, significant results were found between group C with P1 (0.000), C with P2 (0.006), P1 with P2 (0.000), P1 with P3 (0.000) and P2 with P3 (0.003). However, test result were not significant berween group C with P3 (0.684).Conclusions There were differences in macroscopics and microscopic features between Wistar rats liver after immersion in formaldehyde and randu honey. The best features showed in samples preserved in 30% Randu Honey solutions.
DIFFERENCES IN PLAQUE INDEX AND NUMBER OF BACTERIAL COLONIES OF ORAL CAVITY BEFORE AND AFTER BEING EDUCATED WITH MODEL STUDY AND VIDEO Alfi Dian Uly Noor; Rebriarina Hapsari; Ira Anggar Kusuma
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30116

Abstract

Background: Based on the results of Riskesdas in 2018, the 10-14 years old group had a prevalence of daily brushing behavior of 96.5%. However, only 2,1% brush their teeth correctly. The ability of brushing teeth can be improved by providing an oral health education.Aim: Was determined the differences of plaque index scores and the number of bacterial colonies growing in oral cavity before and after being educated using study model and video.Methods: This study was a true-experimental research with pre-test and post-test study design with a subject of 20 students. The students devided into 2 groups, 10 students with study model and 10 students with video. The results of plaque index scores and the number of bacterial colonies were taken before and after the students being educated. This study use the Paired T Test and Wilxocon statistical tests.Results: There were significant differences of plaque index scores and the number of bacterial colonies growing in oral cavity before and after being educated using study model and video. (p < 0,05).Conclusion: An oral health education using study model and video were able to decrease plaque index scores and the number of bacterial colonies growing in oral cavity. The video method was more effective than the study model.
THE EFFECT OF CORIANDER LEAF EXTRACT TOWARDS KIDNEY HISTOPATHOLOGICAL FEATURES ON WISTAR RAT INDUCED BY ORALLY ADMINISTERED MERCURY Manda Petrina; Ika Pawitra Miranti; Nani Maharani; Intan Rahmania Eka Dini
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30095

Abstract

Background: Mercury’s a toxic heavy metal that damages the kidney through generation of Reactive Oxygen Species (ROS). Previous study has established that coriander leaves contained high level of antioxidants. However, there hasn’t been any experiment that examined renoprotective effect of coriander leaf extract toward the kidney of Wistar rat induced with orally administered mercury.Objective: To examine the nephroprotective activity of coriander leaf extract towards Wistar rat’s proximal tubules induced with orally administered mercuryMethods: : Experimental study with post test only control group design using 20 male Wistar rats divided randomly into 4 groups as samples. Group K0 without treatment, Group K(-) was administered 10 mg/ kgBW mercury chloride orally, Group P1 was administered 10 mg/kgBW mercury chloride and 100 mg/kgBW coriander leaf extract orally, and Group P2 was administered 10 mg/kgBW  mercury chloride and 200 mg/kgBW coriander leaf extract orally. The study was carried for 14 days after which the kidneys were examined microscopically.Results: The mean values for damaged proximal tubules were as follows: group K0 2,44±1,19; group K(-) 4,76±3,77; group P1 4,52±2,18; group P2 2,60±1,38. Mann-Whitney test showed significant differences between group K(-)>K0 (p=0,009); group P1>K0 (p=0,001); group P2<K(-) (p=0,015); group P1>P2 (p=0,001). Insignificant differences were found between group P2> K0 (p=0,936) and group P1<K(-) (p=0,579).Conclusion: Coriander leaf extract could reduce the number of damaged proximal tubules from mercury ingestion, with dose of 200 mg/kgBW showing better result than 100 mg/kgBW.Keywords: antioxidants, coriander leaf, kidney, mercury
INFECTION THAT UNDERLIES THE OCCURRENCE OF FEBRILE SEIZURES: A CASE REPORT OF A 2-YEAR-OLD BOY WITH COMPLEX FEBRILE SEIZURE Dimas Tri Anantyo; Ayu Anggraini Kusumaningrum; Nuh Gusta Ady Yolanda; Vinandra -
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.28202

Abstract

Background: Febrile seizures are seizures associated with fever during childhood that most often occurs in children ages six months-five years, with a peak incidence of 18 months Although febrile seizures generally have a good prognosis, they can signal an underlying serious acute infectious infection. This report aims to present a case of febrile seizures associated with the underlying extracranial infection in Semarang.Method: This report describes the anamnesis, physical examination, and supporting examination in patients with febrile seizures.Case: A 2-year-old boy coming to the ER with complaints of seizures that accompanied by fever, When the child seizures are unconscious, after the seizures the child cries.Discussion: The patient came with seizures accompanied by fever three times before being taken to the hospital, the duration of the seizure ± 10 seconds, with a range of ± 2 hours between the first, and the next seizures, twitching convulsions throughout the body, eyes glared upwards, when the child got the seizure, he was unconscious, and after a seizure, the child cries. Three days before, the child had a fever and a cough with yellowish phlegm. On physical examination, It was found ronchi in both lung fields. From x-ray obtained bronchopneumonia picture. Patients diagnosed with complex febrile seizures and bronchopneumonia.Conclusion: Patients were diagnosed with complex febrile seizures and bronchopneumonia, treated for six days, and sent home because the patient's clinical condition improved. Infection is associated with the incidence of febrile seizures.
THE CORRELATION BETWEEN MEAN ATERIAL PRESSURE AND BLEEDING VOLUME WITH THE NATIONAL INSTITUTE OF HEALTH STROKE SCALE (NIHSS) SCORE FOR INTRACEREBRAL HEMORRHAGE PATIENTS Shonia Syvafiftyan Rosaline; Hermina Sukmaningtyas; Arinta Puspita Wati; Sukma Imawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30061

Abstract

ABSTRACT Introduction: Intracerebral hemorrhage refers to primary, spontaneous, and non- traumatic bleeding that occurs in the brain parenchyma. Intracerebral hemorrhage accounts for approximately 10-20% of all stroke. The most common risk factor for non-traumatic hemorrhagic stroke is hypertension. The increase in Mean Arterial Pressure leads to the incidence of intracerebral hemmorhage. The NIHSS is a systematic assessment tool that quantitatively measures stroke associated with neurologic deficits. Neurological deficits that occur in intracerebral hemorrhage occur because blood enters the brain parenchyma. The incoming blood was measured by the Automatic Volume Method (software volume evaluation), namely the calculation of volume by computer software on the CT Scan tool.Aim: To determine the correlation between Mean Arterial Pressure and bleeding volume with NIHSS score in intracerebral hemorrhage patients.Methods: The research design used in this study was cross sectional. The sample of this study was 40 research subjects using purposive sampling, this study has independent variables, namely Mean Arterial Pressure and bleeding volume, while the dependent variable is the NIHSS score (National Institute of Health Stroke Scale). This study conducted an analysis using Spearman's.Results: : The results of this study indicate that there is no significant relationship between bleeding volume and NIHSS score (p = 0,157, r = 0,228) and there is no significant relationship between MAP and NIHSS score (p = 0,268, r = -0,179)Conclusion: There is no statistically significant relationship between Mean Arterial Pressure and bleeding volume with the NIHSS scoreKeywords: Mean Arterial Pressure, Bleeding Volume, National Institute of Health Stroke Scale, Intracerebral Hemorrhage

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