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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 127   128   129   130   131 
Penelitian Kasus Trachoma pada Murid Sekolah Dasar Mu'tasimbillah Ghozi Mu'tasimbillah Ghozi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 03 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Trachoma is a specific communicable keratoconjunctivitis, usually of chronic evolution caused by an agent belonging to the psittacosis - lymphogranuloma - trachoma group of atypical viruses and characterized by follicles, papillary hyperplasia, pannus, and in its later stages, by cicatrizadon". it is a well known eye disease in Indonesia, since many districts have their specific names for trachoma. The progress of trachoma depends on sociohygienic condition in the environment. The progress of trachoma in an area is indicated by its frequency in the area.An investigation of the disease among pupils will give a lower frequency than in the community, but it is valid as a parameter of the progress of the disease.Key Words: communicable disease - trachoma eradication - school health units - keratoconjunctivitis - trachoma
Secular changes in body size and menarche age of Javanese adolescent in Yogyakarta Neni Trilusiana Neni Trilusiana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 04 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Secular changes observed in human development are very sensitive bioindicators of social stresses, social and economic changes, as well as pollution and transformation of the natural environment. Environmental factors, such as nutritional habits, lifestyle and infectious diseases appear to be the main causes of differences in growth and maturation between ethnic and social groups. Objectives: This study was undertaken to know the secular changes in body size and menarche age of Javanese adolescent in Yogyakarta.Methods:The sample consisted of 562 Yogyakarta adolescent (300 girls and 262 boys), ranging from 11 to 18 years of age, measured in August - September 2005. For comparison, data on body size and menarche age of Yogyakarta adolescent examined in 1982 by Aswin et al were used. Measurements of stature and height, and menarche age were obtained for two samples of the Yogyakarta adolescent. Means and standard deviation were calculated for each measurement and for menarche age. Results: The results for stature, weight and menarche age of adolescent measured in 2005 wee greater compared with other Javanese Yogyakarta samples adolescent 23.years ago. Significant positive trends instature, weight and menarche age were apparent between the two samples: 7.37 cm (5.1                        %),  9.21   kg(26.1   %) and 16.6 months (10.6 %), respectively.Conclusions: In summary, the results show a positive secular trend in body dimensions (height and weight) and menarche age, and this can be related to improvement in living conditions in Yogyakarta, especially during the last 23 years. Key words: secular change - anthropometric - menarche age - adolescent 
The frequency of non tuberculosis mycobacteria among isoniazid resistant Mycobacterium isolates and the pattern of resistance to antituberculosis drugs Ning Rintiswati Praseno
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 42, No 01 (2010)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Non tuberculosis mycobacteria (NTM) could be the causative agents of various clinical infections, especially inimmunocompromised individuals. However, frequency of this bacteria among Mycobacterium isolates is not yeknown. Morover, their pattern of resistance to antituberculosis drugs has not been reported. The aim of the study isto determine the frequency of NTM among isoniazid resistant Mycobacterium isolates and the pattern of resistanceto antituberculosis drugs. The clinical isolates of isoniazid-resistant mycobacteria collected from several laboratoriesin Java were cultured on Lowenstein Jensen (LJ) medium and followed by drug sensitivity testing. Identification ofNTM was based on standard microbiological test: colony morphology, duration of growth, acid fast staining, andbiochemical test (niacin test and nitro benzoic acid medium test). All isolates were resistant to rifampicin, 81.20%were streptomycin resistant, and half of them were resistant to ethambutol. Pattern of resistance to the secondline antituberculosis drugs (ciprofloxacin, kanamicin, and ofloxacin) was variable with the range of 37,5%to 62,5%.In conclusion, almost all NTM isolates were resistant to rifampicin and streptomycin, whereas more than half ofisolates were resistant to the second line drugs (ciprofloxacin, kanamicin, and ofloxacin).Key words: NTM- isoniazid resistant- pattern of resistance – antituberculosi drugs
Carcinoma anaplastika nasopharynx Soetarjo Tjokromihardjo Soetarjo Tjokromihardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 03 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: nasopharynx, tumor ganas
Optimal temperature for normal human skin fibroblast proliferation and glucose uptake, an in vitro study DeviArtami Susetiati, LailyNoorQomariah Sunardi Radiono, Yohanes Widodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 03 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Devi Artami Susetiati, Laily Noor Qomariah, Sunardi Radiono,Yohanes Widodo Wirohadidjojo -Optimal temperature for normal human skin fibroblast proliferation and glucose uptake; In vitro study Background: Wrinkles is caused by a decrease in collagen synthesis and an increase in collagen degradation. Collagen synthesis depends on fibroblast proliferation. Collagen synthesis needsglucose, so that collagen synthesis may be expressed by the increase in glucose uptake. Skin rejuvenation with heating may increase the collagen synthesis. The effect of short-term heating and optimal temperature on fibroblast proliferation and glucose uptake has not yet been defined. Objective: This study was aimed to determine the optimal temperature of short-term heating for normal human skin fibroblasts proliferation and glucose uptake. Methods: A simple experimental study was conducted on 3rd passage subculture of normal human skin fibroblasts culture, isolated from 2 patients. Normal human skin fibroblasts with complete DMEM were classified into 5 groups, and then heated for a minute with thermocycler-machine at 36°C, 46°C, 56°C, 66°C, and 72 °C. Those cells were incubated for 7 days in complete DMEM and subsequently fibroblasts proliferation was measured by MTT -assay. Glucose uptake was measured by glucometer Medisafe- Terumo. The differences in glucose uptake and fibroblasts proliferation were analyzed with one-way Anova. Result: Optimal temperature for fibroblasts proliferation was 46°C, and 66°C for collagen synthesis. Conclusion: Skin rejuvenation based on heating could be performed at two different temperatures, each cycle consisted of 66°C on first heating, and seven days later, at 46°C on second heating.
Anemia in rural and urban school children and its correlation with nutritional status in Yogyakarta A. Samik Wahab A. Samik Wahab
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 02 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A survey on anemia has been conducted on 94 school children in Yogyakarta of whom 46 were from rural and 48 from urban private elementary schools. The subjects ranged in age from 6 to 12 years. The frequency of anemia showed significant difference between the two groups (p < 0.01). The result showed that 39.13% of the rural and 6.25% of the urban school children were anemic. More girls were anemic than boys, namely 13.83% of the girls and 8.5% of the boys (p < 0.05). Amongst the causes of anemia in the rural area is thought to be worm infestation and other factors enhancing iron deficiency. It is suggested that iron supplement to adolescent girls is important. Key Words: anemia - hemoglobin - anthropometric measurement - nutritional status - iron deficiency
Studi variasi index acromiocristalis Suyanto Suyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 03 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Index acromiocristalis ialah perbandingan lebar panggul dan lebar bahu dikalikan 100. Olivier (1969) mengatakan bahwa nilai index acromiocristalis itu tergantung pada:- perkembangan panggul- sex- derajat timbunan lemak- ras- ripe perawakan.Maksud tulisan ini ialah untuk mengetahui variasi index acromiocristalis dari beberapa aspek, mengingat tulisan yang lengkap tentang index acromiocristalis di Indonesia belum ada.Materi diambil dari sebagian data anthropometris yang dikumpulkan oleh Seksi Anthropologi Ragawi Fakultas Kedokteran Universitas Gadjah Mada sebanyak 1880 orang yang terdiri dari 1220.1aki-laki dan 660 perempuan yang berumur 6 tahun sampai dengan 29 tahun.Data menunjukkan bahwa pada perempuan ada korelasi positif yang kuat antara index acromiocristalis dengan umur, sedangkan pada laki-laki tidak demikian, dan index acromiocristalis pada perempuan mempunyai kisaran 49,32 - 114,29, sedangkan pada laki•laki 55,67 . 101,66, serta hal-hal lain yang menarik.
Incompleted gestational age as a risk factor for developmental disorder at 6 up to 36 months of age. Pramudito Pramudito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: In developed countries, survival rate of preterm baby with gestational period more than 26 weeks has increased. Most studies on developmental outcomes were conducted on preterm baby with gestational period of less than 32 weeks. On the other hand, in developing countries the mortality rate of preterm baby with gestational period of less than 32 weeks is still high.Objective: To assess whether the incompleted gestational age is a risk factor for developmental disorder at 6 up to 36 months of age.Methods: Sixty four subjects born between 2001 April 1 to 2004 January 31 in Dr. Sardjito Hospital were enrolled, consisted of 31 children with incompleted gestational age (exposed group) and 33 children with completed gestational age (unexposed group). The developmental milestone was assessed using the DenverDeve/opmenta/ Screening Test/DDST (Denver //). Age line adjusment is used for exposed grou when the subject was born 4 weeks before completed gestational age and less than 3 years old.Results: There was no statistically significant diferrence on the prevalence of developmental, disorder at 6 to 36 months of age between exposed group and unexposed group in every area i.e. for gross motor: RR (95% Cl): 0,87 (0,24-3,19); language RR (95% Cl ): 1,48 (0,30-7,23 ) and personal social RR (95% Cl): 1,10 (0,10-17,83) or developmental conclusion: RR (95% Cl): 0,75 (0,23-2,48Conclusion: On the basis of developmental screening using DDST (Denver 11) incompleted gestational age (32-36) weeks was not a risk factor for developmental disorder at 6 to 36 months of age. Key words: incompleted gestational age - development disorder - Denver Developmental Screening Test/ DDST (Denver ll).
Management of early breast cancer with breast conserving treatment : Evaluation of cases in Yogyakarta T. Aryandono T. Aryandono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 01 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Breast conserving treatment (BCT) can be done for early breast cancer, with the same survival as mastectomy. The patients should not lost the breast resulted from the treatment. Objective: To evaluate the patients with breast conserving treatment in two hospitals in Yogyakarta, in connection with locoregional recurrence, distant metastasis, cosmetic result and general condition. The results can be used for improving the technique of breast conserving treatment in this region. Methods: Five patients with BCT from 1996 until 2001 were treated with wide excision (lumpectomy), axillary dissection level I and II, and radiotherapy 5000 cGy. Histopathological examination, estrogen and progesterone receptor and c-erbB-2 examination were conducted for these patients. All patients received hormonal adjuvant treatment with tamoxifen, no one received adjuvant chemotherapy.Results: The age range was 28-51 years old, stage one, maximum diameter of tumor was 1.5 cm. Most of them were invasive duct carcinoma, with positive ER, PR and c-erbB-2. Follow up from 8 to 66 months, with median follow up 37 months. No locoregional recurrences, one with distant metastasis (lung). The cosmetic result as well as the general condition were good.Conclusions: Breast conserving treatment had been done on patients and resulted in good cosmetic result, no locoregional recurrences and good general condition. With early detection and good patient selection, the patient should have not lost the breast with the same survival as in mastectomy.Keywords: breast conserving treatment- lumpectomy - radiotherapy - estrogen receptor - progesterone receptor.
Initial Study of Production of Bacillus thuringiensis israelensis Using Locally Obtained Substrates Soesanto Soesanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 03 (1992)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Bacillus thuringiensis israelensis diketahui sebagai entomopatogen nyamuk ades aegypti yang merupakan vektor penyakit demam berdarah.Telah dilakukan percobaan produksi Bacillus thuringiensis israelensis dengan menggunakan medium yang mengandung bahan lokal terasi udang, melase dan tepung kedelai. Hasil uji toksisitas (bioassay) terhadap Final Whole Culture (FWC) dengan bahan lokal yang murah menunjukkan potensi sebagai agensia bioinsektisida.Key Words: entomopathogen - Bacillus thuringiensis - bioinsecticide - Aedes aegypt - toxicity bioassay

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