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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
Catamenial epilepsy Harsono Harsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 01 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The true frequency of menstrually related seizures (catamenial epilepsy) is unclear. This is due in part to the fact that at present there is no universally accepted definition of this entity. Because of such arbitrary definition, a variety of therapeutic strategies for controlling seizures related to hormonal fluctuations have been recommended. With respect to the uncertainty of catamenial epilepsy criteria, the principles of physiologic changes related to hormonal fluctuations in women with epilepsy should be understood. Based on the knowledge of hormonal changes and characteristics of epilepsy, a detailed history taking should be carried out properly. This strategy will be useful for establishing diagnosis and planning appropriate treatment.Keywords: catamenial epilepsy - definition - seizure - therapeutic strategy - hormonal fluctuations.
Evaluation of primary health workers training program to provide psychoeducation to family caregivers of persons with psychotic disorder Carla Raymondalexas Marchira; Warih Andan Puspitasari; Ida Rochmawati; Siti Mulyani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 47, No 01 (2015)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.67 KB) | DOI: 10.19106/JMedSci004701201505

Abstract

ABTRACT Many persons suffering psychotic illnesses, such as schizophrenia, are largely untreated in low income countries. In these settings, most persons with severe mental illness live with their families. Thus, families play a particular critical role in determining whether a person with a psychotic illness will receive treatment and what the quality of treatment. Psychoeducation has proven to be extremely effective in helping families develop the knowledge and skills which is necessary to help their family members. Indonesia has a national policy to integrate the management of mental health problems into the primary health care system. However, in practice, such care does not implemented effectively. A preliminary study in primary health centers in two districts of Bantul and Gunung Kidul regency, Yogyakarta province, showed that there was very little or there is not any training for health care workers on diagnosis and treatment of psychotic disorder. This study was conducted to evaluate the effectiveness of the training program for health workers in three primary health centers in Yogyakarta, Indonesia, to provide psychoeducation to family caregivers for persons with psychotic disorder. A quasi-experimental study with the approach of one group pre and posttest design was performed in this study. Fortythree health workers in 3 primary health centers in Bantul and Gunung Kidul, Yogyakarta were trained every week for a month to provide psychoeducation to family caregivers who live with psychotic disorder patient. Result showed that the baseline score of knowledge of schizophrenia among health workers in 3 primary health centers in Bantul and Gunung Kidul before training were not significantly different (p=0.162). After the psychoeducation training program there were significantly different (p=0.003) of the score of knowledge of schizophrenia among health workers in 3 primary health care centers compared with before training. For conclusion, the training program to provide psychoeducation to family care providers of persons with psychotic disorder for primary health workers was effective to increase their knowledge of schizophrenia.
Relationship between anxiety and sexual disorders Soewadi Soewadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 04 (1992)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Many factor may determine whether a marriage will be succesful or not. Among those factors, probably the important one is the desire and ability to adjust, to each other in satisfying sexual experience. In man the process of sexual activity is somewhat complicated. The act ought to be widely understood, since much human happiness depends on proper sex knowledge and adjustment. Psychological factors may play a role in the failure of sexual satisfaction.Considering the facts above, the author assumes that there will be a relationship between anxiety and sexual problem in married life. The assumption encouraged the author to study the problem.A survey of sexual problems during married life was carried out in the Special Province of Yogyakarta, among cases who proposed divorce.Results show that most of the cases with sexual problems present anxiety. A comparison between the cases with and without sexual problem, shows significant differences in the distribution of anxiety.Key Words: sexual problem - married life - anxiety - sexology - psychiatry
Application of non-specific esterase enzyme microassays to detect potential insecticide resistance of Aedes aegypti adults in Yogyakarta, Indonesia Sugeng Juwono Mardihusodo Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 04 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

By bioassay Aedes aegypti larvae collected from Yogyakarta were found to be susceptible to temephos and malathion and by using microplate enzymatic assay Ae. aegypti larvae collected from the same sites were potentially resistant to the organophosphate insecticides due to elevated esterase activity in hydrolyzing a-naphthyl acetate substrate used in the enzymatic reaction from the same sites might be potentially resistant to OP insecticides due to the same mechanism. The homogenates of the mosquito adult stages from the fields were microassayed using a-naphthyl acetate substrate compared to that colonized in the laboratory. From a series of studies the results were concluded that Ae. aegypti adults in Yogyakarta were susceptible and potentially resistant to insecticides due to elevated a-naphthyl acetate esterase activity.Key words: Aedes aegypti - organophosphate insecticides - insecticide resistance - non-spesific esterase -biochemical test.
Effect of homocysteine and antioxidants on peroxidation lipid of essential hypertension in Central Java Indonesia Sunarti Ria Maudisa Rizka H Asdie, Mohammad Hakimi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 04 (2008)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: The increase in the homocysteine level is related to the heightening of blood pressure and hypertension risk. Hyperhomocysteinemia encourages the production of free radical which can oxidi2e lipid. Lipid peroxidation can be prevented by several antioxidant such as vitamin C and E.Objective: This study is aimed at finding out the nature of the interaction effect between homocysteine and antioxidant vitamins on malondialdehyde level in essential hypertension.Method: This study was a case-control nested to NSurveiliance of Non-Communicable DiseasesN in Purworejo, Central Java. The subjects were men, essential hypertension and 20-60 years old that have normal value of urine creatinine, blood glucose, cholesterol and triacylglycerol. They have been take antihypertension drugs. The blood glucose, cholesterol, triacylglycerol, urine creatinine, vitamin C and malondialdehyde (MDA) levels were measured by spectrophotometer. Whereas the total plasma homocysteine and vitamin E were determined by HPLC.Result: The homocysteine level in the cases was higher than that of the control and was significantly different (P = 0,027). There were not significantly different of the vitamin C, vitamin E, and MDA between the cases and the control (P=0.538, P=0.390, and P=0.536) respectively. The MDA was positively correlated with homocysteine (P=O.OOOI and negatively correlated with vitamin E (P=0.029), but it was not negatively significant correlated with vitamin C (P=0.0671. The correlation had r= 0.417; R2=0.174 and F=7.713.Conclusion: The high homocysteine level is one of hypertension risk factors and its effect through oxidative stress. The effect can be prevented by antioxidant vitamins, specially vitamin E.Key words: homocysteine - antioxidants - peroxidation lipid - essential hypertension - avanese
Uji Diagnostik Kriteria Baru Demam Reumatik A. Samik Wahab A. Samik Wahab
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 02 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

More than 40 years ago T. Duckett Jones published a set of guidelines for the diagnosis of acute rheumatic fever that became known as the Jones criteria. The criteria became widely used throughout the world and provided a uniform diagnostic reference for national and international epidemiologic, prevention and treatment studies.Although the basic concepts proposed by Jones have been retained, modifications of the original criteria should be done to simplify the criteria in order to be used as a diagnostic tool at the primary health care, type D and C hospitals and for surveillance. These new simple diagnostic instruments should have good sensitivity, specificity, positive and negative predictive values using Jones criteria as gold standard.Eight criteria have been considered as a new simple 'diagnostic instrument, with various sensitivity, specificity, positive predictive and negative predictive values. The optimum result of this diagnostic test is in the eight criteria, i. e. the criteria of specific murmur.Key Words: rheumatic fever -- cardiomegaly -- heart failure -- Jones criteria -- specific murmur
Jenis-jenis nyamuk di kota Madya Yogyakarta Mardihjah Mardhijah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 01 (1977)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: familia culicidae, anophelinae, culicinae, toxorhynchitiane
Potency of Anticandida extract combine by in vitro and in vivo Ning Rintiswati Ning Rintiswati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 4 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Antifungal agents are routinely used for the treatment of fungal infections. It is very likely however, that resistance of fungi to antifungal agents will emerge in the near future and the development new antifungal agent is very slow. To cope with the problem, it is important to search new antifungal agent from natural resources for yhe treatment of various diseases. It was also reported that bee honey has antibacterial property.Objective: To know the in vitro and in vivo effect of crude honey, aether-extracted honey and its residual part on Candida albicansMethods: Samples used in this experiment were crude honey, aether-extracted honey and residual part of extracted honey. Each sample was tested for its anticandidal activity with macrobroth dilution method using casein-yeast extract-glucose medium. Minimal inhibitory concentration and minimal fungicidal concentration were determined for each sample.Result: The result showed that extracted honey anticandidal effect in vitro at minimal inhibitory concentration was 0.3125% v/v and its residual was 25%, whereas crude honey has no inhibitory in vitro effect on Candida albicans. Minimal fungicidal concentration of extracted honey and its residual were 0.31255 and 50% v/v respectively. In vivo study showed that treatment group recovered faster than control group.Conclusion: Aether extracted honey and its residual have anticandidal activity in vitro. The extract have effect on recovery of candidal infected mice.Key words: Candida albicans - bee honey - antifungal-minimal inhibitory concentration - candidal infection recovery 
Aged and Aging Wasilah Rochmah Wasilah Rochmah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Since the last two decades the history has witnessed that aging and gerontology have been the focus of extensive discourse and concern. Aging has arrived as an issue and object of study, and academic community recognized aging as a legitimate area of study. As the number of elderly has increased exponentially, the professional and paraprofessional occupations dealing with that problems of the elderly has also increased. Chronologically, a person is considered to be old if he/she experiences a long life. Old is not only viewed by its chronological aspect, but also by its physical and psychological aspects as well. Aging results in body structural and functional changes, and it generates impairment, disability, and sometimes conform to a disease. The mechanisms and factors underlying aging process are still controversial. In attempts to explain aging process some numbers of theories have been proposed. It is, therefore, the emerging issues concerning old and aging process are: how the aging process takes place and which theories are still plausible? Aging process is a life-long process, characterized by body- failures in maintaining homeostatic conditions to physiological stresses. There are a variety of theories of aging that are proposed in which some of them are still plausible.Keywords: elderly - aging process - body structural & functional changes - impairment & disability -theories of aging
Exclusive breastfeeding and risk of atopic dermatitis in high risk infant Martaviani Budiastuti, Setya Wandita, Sumadiono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: WHO recommends exclusive breast-feeding for 6 months becaase it is highly beneficial. It hasbeen proven by a number of studies to be advantageous in preventing various infectious diseases. However,its role in preventing allergic diseases especially atopic dermatitis in infant remains uncertain until recently.Objective: To find out whether high risk infant who did not receive exclusive breast-feeding would have agreater risk to suffer from atopic dermatitis.Method: We conducted a case-control study. Data were obtained from Pediatric Outpatient Clinics andDermatology and Venerology Outpatient Clinics, Dr. Sardjito Hospital Yogyakarta. Case group was highrisk infants with atopic dermatitis, while control group was high risk infants but not having the disease.Statistical analysis used Chi-square and degree of significance was stated as Confidence Interval (CI) of95% for each Odds Ratio (OR). Multivariate analysis was performed by using logistic regression method.Results: The study included 88 subjects with 44 subjects for case and control groupas well Logisticregression showed that not receiving exclusive breast-feeding was statistically significant risk factor toatopic dermatitis in high risk infant {OR 3.72 (95% CI: 1.40-9.90); p 0.01}.Conclusion: High risk infant not receiving exclusive breast-feeding will have greater risk to develop atopicdermatitis.Keywords: exclusive breast-feeding, atopic dermatitis; high risk infants.

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