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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 174   175   176   177   178 
Spesifisitas antibodi monokional anti protein ekskretori-sekretori Brugia malayi terhadap protein nematoda lain Soeyoko Soeyoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 02 (1999)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Previous studies using hybridoma technique had produced monoclonal antibodies against excretory-secretory (ES) protein of B. malayi i.e. Fesi, Fes3, Fes7, Fesl3 and Fesi5. Those monoclonal antibodies will be used to diagnose malayan filariasis in the endemic areas.Objectives: To reveal binding specificities of those monoclonal antibodies to ES protein of B. malayi, heterologous protein i.e. Ascaris lumbricoides, Necator americanus and homologous protein i.e. Brugia pahangi.Methods: Binding specificities of those monoclonal antibodies to other nematodes protein were assessed by ELISA and inhibition ELISA techniques.Result: Those monoclonal antibodies showed different binding specificities profiles. Fesi, Fesi3 and Fes. revealed specific reaction to ES protein of B. malayi but they did not react to heterologous and homologous protein. Fes3 and Fes7 did not reveal binding specificities to heterologous protein but they had low cross-reactivity to homologous protein. Cross-reactivity values of Fes3 and Fes7 were 33.3% and 22% respectively. Conclusion: Monoclonal antibodies against ES protein of B. malayi i.e. Fesi, Fesi3 and Fesl5 revealed specific reaction to ES protein of B. malayi, but Fes3 and Fes7 had low cross-reactivity to protein of B. pahangi.Key words: binding specificity - monoclonal antibody - ES protein - heterolog protein - homolog protein - ELISA.
Bone scanning study with Tc-99m-MDP for screening of malignant metastasis in patient with lung carcinoma Bagaswoto Poedjomartono Bagaswoto Poedjomartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 01 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Bone scanning study with Tc-99m-MDP is usually used for screening of malignant metastasis. This method is not invasive, very sensitive but not specific. Indications of bone scanning study are detecting metastasis, evaluation of therapy and follow up the disease. The dosis of Tc-99m-MDP is 15 mCi injected into vena cubiti and after 2-4 hours, scanning will be done. Metastatic lesions are indicated by hyperactive areas on the bone. This scanning is done for evaluation how far the bones are involved in patients with lung carcinoma.Key words: lung carcinoma - bone metastasis - Tc-99m-MDP scanning - radiology - oncology
Hubungan Sistem Lymphe Dan Vena Pada BNagian Superficial Jantung Djaka Prakosa Djaka Prakosa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 02 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

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Histological organization of the subfornical organ of the albino rat. A histochentisuy study. Daryanto Daryanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 01 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The objectives of this study are to provide an account of the well-established common histological characteristic of the subfornical organ, an overview of the controversial issues regarding its structure, and to point out the histological organization which is still unclear.This histochemistry study involving the light microscopy, transmission electron microscopy and scanning electron microscopy. The albino rats which did not receive any treatment were stained with several types of staining techniques for light microscopy, i.e. hematozylin-eosin, toluidin-blue, methylene-blue, the Russell's acid-phosphotungstic-hematozylin, Bodian's protargol, Weil's hematozylin & ferriamonium-sulphate, and the Gomori's chrome-alum-hematozylin phlozine methods. This study was carried out in the Department of Histology, Faculty of Medicine, Gadjah Mada University, Yogyakarta by using 85 albino rats of the LMR (Lembaga Makanan Rakyat, Jakarta) strain. For transmission electron microscopy 19 albino rats were used: 10 adult albino rats of the LMR strain were done in LAKFIP UGM, Yogyakarta; five adult albino rats of the Wistar strain were done in Faculty of Graduate Studies, Mahidol University, Bangkok, Thailand; and four adult albino rats of the Wistar strain were done in First ...Key Words: subcomical organ - albino rat - neuron - neuroglia - ultra structures of blood capillaries
A critical evaluation of peripheral blood smear in the diagnosis of thalassemia syndrome Sunarto Sunarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 01 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The severe affected thalassemla syndrome Is common In Southeast Asian countries. Considering that the feature of its peripheral blood smear Is typical, this study was aimed at investigating the diagnostic value of the blood smear in thalassemia syndrome. Sixty five patients with severe anemia and splenomegaly who were admitted or came for follow up to Sardjito General Hospital in the period of 1996 and 1997 had been enrolled In this study. The peripheral blood smear was assessed, whether thalassemla or nonthalassemia, by two laboratory technicians, each of them read blindly each smear at two occasions with at least two weeks interval. The gold standard for diagnosis of thalassemla major was the evidence of increased HbA2 (>3,5% of total Hb) In both parents and for thalassemla-hemoglobin E disease was the increased HbA2 in one of the parents and the presence of HbE in the other. The measurements of HbA2 and HbE were carried out by quantification of HbA2 fraction following hemoglobin electrophoresis on cellulose acetate membrane (CAM) electrophoresis. The results of blood smear reading showed good intrarater agreement with kappa = 0.691 by the first rater and 0.634 by the second rater). The interrater agreement was high moderate to good (kappa = 0.567 - 0.728). The first reading by the first rater, the second reading by the first rater, the first reading by the second rater, and the second reading by the second rater showed sensitivities of 0.780, 0.780, 0.878, and 0.805 respectively; specificities of 0.708, 0.958, 0.542 and 0.792 respectively; positive predictive values of 0.820, 0.969, 0.766, and 0.868 respectively; and negative predictive values of 0.650, 0.719, 0.722, and 0.704 respectively. The peripheral blood smear has high sensitivity and specificity for diagnostic test of thalassemia syndrome.Key words: thalassemia syndrome - blood smear - hemoglobin electrophoresis - sensitivity and specificity -predictive value
Trends in the development of medical science and technology at the beginning of the 21s1 century T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Mau is the only creature that could think about his future, and therefore, prepares for it and actually shapes it, or even invents his future. Predictions about the future are more relevant nowadays because of the importance of intergenerational justice, of learning from history and of adaptational preparation in view of rapid technological changes. Scientific and technological development will unavoidably influence the course of medical sciences and practice. The sociocultural impact of this development will affect even the essence of life itself, not only the human society, food strategy, demography, disease pattern, and environment. Most important is the impact on ethics and religion, creating frustration, uncertainties, emptiness and insecurity in life which consequently demands the revival of both and assure their existence in the next century. It is suggested that scientific ethics will be intensified, religious interpretations adjusted to the development of civilization without deviating from its basic principles, and that a new paradigm in medicine is needed in order to restore the disequilibrium brought forth by the culture of overconsumption and overcompetition. Key Words: futuristics - medical sciences - technological impact = ethics - religion
The prevalence of intestinal parasites in orphanages in Yogyakarta Suyoko Suyoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 01 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Stool specimens for microscopic examination collected from orphanages in Yogyakarta indicated the species and the overall percentages of prevalence of human intestinal parasites. These samples were examined in our laboratory by direct smear and concentration methods. The overall percentage of the sample population found infested with intestinal helminths was 43.4 and of intestinal protozoa was 39,8.KeyWords: intestinal helminths - intestinal protozoa - direct smear - Ritchie method - anal swab
Paradigm in the recent management of chronic myocard ischaemia. Bambang Irawan Bambang Irawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 02 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Until now coronary heart disease is the number one killer in the world. Angina pectoris is one of the clinical manifestations of coronary heart disease. If there is an insufficient oxygen supply to meet the need ischaemic myocard will happen.Life style changing, drug treatment and operative procedure are applied for the management of pain caused by myocardial ischaemia. According to many big anti-thrombotic trials statin, ACE inhibitor, calcium inhibitor, beta blocker and nitrate are very helpful in the management of chronic coronary artery disease. Myocardial laser revascularization, enhanced external counter pulsation and spinal cord stimulation are alternative procedures in which we can handle it with common management. While conventional therapies are continued to be improved, strategies to increase myocardial circulation by stimulating formation of collateral vessels around the obstructed coronary arteries are also in development. These approaches include angiogenesis, protein transfer, gene therapy and cell therapy. It is hoped that those approaches will safely and effectively applied in the management of chronic coronary artery disease. Key words: Coronary heart disease - chronic stable angina - myocardial ischaemia - new approaches
Behavior of the B. malayi microfilariae in the peripheral blood of human carrier in the intergradation area of Mahakam Delta East Kalimantan. FA Sudjadi FA Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 02 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Nonperiodic form of B. malayi of human parasite was recently identified in East Kalimantan by Sudjadi as different subspecies in addition to the previously known periodic and subperiodic form of infraspecific variation.Objectives: To detect any changes in microfilarial periodicity in the intergradation area of Mahakam delta with the subperiodic type from South Sulawesi, genealogically related to local population. Methods: Periodicity examinations were carried out on the microfilarial carriers discovered in the B. malayi endemic area of Mahakam delta. Blood examinations (60 mm3 blood) was carried out every 2 hours, in 24 hour cycles. Result analysis was performed using Aikat and Das statistical formula. Results: Six microfilaria carriers of B. malayi were examined for periodicity study. Cases of the nonharmonic or noncircadian form were predominantly (in 5 cases) recorded and only in one case the microfilariae were showed a harmonic or circadian wave pattern,, but with a peak hour at day time, ie 15.54'00". Conclusion: No change of the microfilarial periodicity was recorded in the intergradation zone of Mahakam delta. The B. malayi filarial worm was still showing a nonperiodic wave pattern as different subspecies apart from the subperiodic and periodic form of filarial worm.Key words: B. malayi - microfilarial periodicity - intergradation area - non periodic form - subperiodic form
Prevalensi dan intensitas infeksi cacing tambang di Daerah Yogyakarta dan Surakarta Soenarto Soenarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 01 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: prevalensi, penyakit cacing tambang

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