cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Nurhadiyahya
Contact Email
nurhadiyahya@ugm.ac.id
Phone
+6289672800034
Journal Mail Official
jmedscie@ugm.ac.id
Editorial Address
https://jurnal.ugm.ac.id/bik/about/editorialTeam
Location
Kab. sleman,
Daerah istimewa yogyakarta
INDONESIA
Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 45   46   47   48   49 
Model terapi gen menggunakan sel fibroblas rekombinan yang dibungkus mikrokapsul. Suatu Kajian In Vivo M. Mansyur Romi, M. Mansyur Romi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 03 (1996)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.011 KB)

Abstract

Current approaches to human gene therapy focus on insertion of a desired gene into autologous cells such as fibroblasts. hepatocytes, bone marrow stem cells or lymphocytes. An alternate strategy to gene therapy through genetic modification of the patients own cells is to implant into different recipients the same engineered cell line under immunologically isolated conditions. This in vivo study shows that human growth hormone (hGH) as a novel reporter gene product from microencapsulated genetically modified mouse cells is detectable in the circulation of allogenic recipient mice. On day 3 of post implantation no hGH was detected, 3 ng/ml of hGH was detected on day 12 and increased during the next 9 days up to 10-fold. The high level of hGH was maintained during days 21 - 33 post implantation and went down afterward to the baseline on day 45. No hGH was detected in the control mouse implanted with the same amount of free recombinant cells.Key Words: Gene therapy - autologous cells - genetic modification - recombinant cells - lymphocytes
Early dejection of glaucoma cases by cupping disc examination
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 04 (1987)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.98 KB)

Abstract

Two cases of glaucomas were found by papil disc examination. In the elder patient, more than 40 years old, glaucoma was diagnosed by tonometric examination. In the younger patient, less than 40 years old, suspected glaucoma was diagnosed by water drinking test. Key Words: papil disc examination - cupping disc ratio - tonometric examination - water drinking test - glaucoma
Management of premature rupture of the membrane Risanto Siswosudarmo, Risanto Siswosudarmo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 01 (1991)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.251 KB)

Abstract

A literature study on the management of premature rupture of the membrane (PROM) is carried out to find out the best method and its impact on maternal and neonatal morbidity.PROM is defined as rupture of the fetal membrane before the onset of true labor. The incidence of PROM varies from 0,7 to 10%. Premature labor and its consequences to the newborn as well as maternal and neonatal infections are complications attributed to early rupture of the membrane.Conservative management for PROM before 37 weeks of gestation is a method used by most obstetricians. Patients should be staying in bed as long as the amniotic fluid is still coming out, no vaginal examination performed, and she should be closedly monitored for signs of infection and prophylac tic antibiotics given. Once the signs of i nfection develop, termination of pregnancy should be carried out and massive antibiotics should be given. Risk of infection becomes evident if rupture of the membrane goes beyond 12 to 24 hours so that prophylactic antibiotics should be given before 12 hours of rupture. Most of the cases will go to labor before 48 hours, although in some cases labor can be postponed for 19, 33, 39, 44, and 55 days. If labor can be postponed for more than 48 hours, the risk of suffering From respiratory distress syndrome (RDS) in neonates is getting lower.The management of premature rupture of the membrane after 37 weeks of gestation depends on the condition of the cervix. Patients with ripe cervix can be induced immediately, but patients with unripe cervix should be managed conservatively.Key Words: PROM - RDS - prophylactic antibiotics - perinatal mortality - maternal infection
The prevalence of intestinal parasites in orphanages in Yogyakarta Suyoko, Suyoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 01 (1980)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.584 KB)

Abstract

Stool specimens for microscopic examination collected from orphanages in Yogyakarta indicated the species and the overall percentages of prevalence of human intestinal parasites. These samples were examined in our laboratory by direct smear and concentration methods. The overall percentage of the sample population found infested with intestinal helminths was 43.4 and of intestinal protozoa was 39,8.KeyWords: intestinal helminths - intestinal protozoa - direct smear - Ritchie method - anal swab
Renoprotective effects of calcium antagonists on kidney disease
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 03 (1995)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.243 KB)

Abstract

There has been a growing number of evidence that calcium antagonists provide a salutary effects in preserving kidneys against acute renal ischemia in patients at increasing risk. Their beneficial effects on cellular and mitochondrial calcium may explain the effects on renal hemodynamics and metabolics. It seems, that they do not directly vasodilate kidney vessels but alter the response towards vasoconstrictor agents. This effect may mediate diuretic and natriuretic effect of calcium antagonists. Effects on tubuloglomerular feedback and autoregulation mechanism in the kidneys play an important role in this regards. The above mentioned effects may provide a significant kidney protection and retard the progress of kidney disease.The results of recent studies show that calcium antagonists exert potentially. beneficial effects on several clinical settings including radiocontrast-induced nephrotoxicity and transplant-associated renal insufficiency, particularly cyclosporine A nephrotoxicity and ischemia during harvesting of kidneys.Key words: kidney disease - calcium antagonists renoprotective - hemodynamics - kidney function
Organisasi Registrasi Kanker Population-Based di Indonesia Soeripto, Soeripto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 03 (1985)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.819 KB)

Abstract

Based on technique of cancer registration there are three types of cancer registry. These types are: 1.pathology department-based cancer registry 2.hospitl -based cancer registry 3. population-based cancer registry. Each of these types has its own method and characteristics. The aim of pupulation-based cancer registry is ib evaluate and control the trends of cancer in the community. This field has very close relation with cancer epidemiology. The prospect of the population-based cancer registry in Indonesia depends on various conditions. It is concluded that the Special Province of Yogyakarta could fulfill the conditions for the purpose of developing population-based cancer registry in Indonesia, while Bali is an ideal place for population-based cancer registry in Indonesia. Therefore, other conditions are needed for this purpose. Key Words: population-based cancer registry - technique of cancer registration - characteristics of cancer registry - cancer control in the community - cancer epidemiology
Factor Vill level given by continuous infusion compared to by bolus in children with hemophilia A undergoing circumcision (case series) Ridwan Sugiarto, Ridwan Sugiarto T
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 04 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.636 KB)

Abstract

Background: hemophilia is the most common hereditary bleeding disorder in children, and can create challenges in the treatment of complicated bleeding episode. Circumcision and other surgical procedures in persons with hemophilia require anticipatory management plan to prevent and treat bleeding prior to, during and following surgery. Prolonged bleeding can be managed by supplement therapy with Factor VIII, administered intravenously by either bolus (BI) or continuous infusion (CI) to achieve hemostatic plasma Factor VIII levels.Objectives: the aim of this study was to compare plasma activity level of factor VIII in relation to the method of intravenous administration.Methods: commencing 4 days post circumcision, five sequential measurements of plasma Factor VIII levels were done at 6 hourly intervals in 4 boys with hemophilia A who received intravenous Factor Vill, either by 81 or Cl.Result: four patients given continuous infusion showed lower level of Factor VIII compared to bolus therapy. Conclusion: bolus therapy has more increased level of Factor VIII compared to continuous infusion. Bleeding was not found in both therapies (Cl or BI). Key words: AHF - continuous infusion - bolus - plasma level
Jalannya asthma bronchiale pada anak Purnomo Suryantoro, Purnomo Suryantoro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 03 (1977)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.344 KB)

Abstract

keywords: asthma bronchiale, syaraf otonom-tidak seimbang, eksema infantil
Secretion of a Novel Gene Product through Micro-encapsulated Recombinant Cells a Preliminary Report M. Mansyur Romi, M. Mansyur Romi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 03 (1994)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.057 KB)

Abstract

Galur sel hasil rekayasa genetik yang berada dalam kondisi terisolasi secara imunologis diharapkan dapat diimplantasikan kepada beragam penerima. Dengan demikian tersedia strategi altematif bagi terapi gena, yang umumnya bergantung kepada modifikasi genetik terhadap sel dari penderita sendiri. Penelitian ini mengamati ekspresi hormon pertumbuhan manusia (HPM) dari hasil rekayasa genetik sel mencit yang ditempatkan di dalam membran imunoprotektif secara in vitro.Sel mencit Ltk" ditransfeksi dengan plasmid pNMG yang mengicode gena HPM dan gena resistensi terhadap G418. Sel-sel yang mensekresi HPM dalam jumlah banyak dipilih untuk dibungkus dengan mikrokapsul berdiameter 300nm yang terbuat dari bahan alginate — polylysine — alginate. Prosedur pengkapsulan tidak mengganggu kelangsungan hidup sel, terbuicti bahwa lebih dari 95% sel masih tetap hidup seusai pengkapsulan. Sepanjang percobaan selama 3 minggu angka sel yang hidup dapat dipertahankan sekitar 90%, jumlah sel di dalam mikrokapsul meningkat lebih dari sepuluh kali lipat, dan HPM di dalam media juga meningkat konsentrasinya. Membran mikrokapsul cukup permeabel, dari perhitungan pada awal percobaan lebih dari 80% HPM yang disekresi dapat berdifusi ke dalam media. Dapat disampaikan bahwa produk gena baru dari galur sel baku hasil rekayasa genetik dapat dihantarkan melewati mikrokapsul dari bahan alginate-polysine-alginate secara in vitro paling tidak selama tiga minggu. Selain itu, prosedur yang dikerjakan cukup memadai bagi kelangsungan hidup sel, lingkungan dalam mikrokapsul dapat mendukung pertumbuhan sel, dan membran kapsul bersifat permeabel bagi produk gena baru.Key words: genetically modified cells-plasmid pNMG-human growth hormone-immuno protection-microcapsule
Penelitian dalam Bidang Kedokteran Jiwa Soejono Prawirohardjo, Soejono Prawirohardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 02 (1989)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.421 KB)

Abstract

The paper describes various methods of problem-solving during the history of mankind and puts special emphasis on discovering and identification of psychiatric problems. Research methodology in general is explained.Then it reviewed similarities between psychiatric research -- and the general, methodology. Finally, the particularities of psychiatric research are discussed.Key Words: research methodology -- psychiatric research -- gold standard diagnosis -- research instrument -- five levels model

Page 47 of 217 | Total Record : 2170

 45   46   47   48   49 

Filter by Year

1973 2023


Reset
Filter By Issues
All Issue Vol 55, No 4 (2023) Vol 55, No 3 (2023) Vol 55, No 2 (2023) Vol 55, No 1 (2023) Vol 54, No 4 (2022) Vol 54, No 3 (2022) Vol 54, No 2 (2022) Vol 54, No 1 (2022) Vol 53, No 4 (2021) Vol 53, No 3 (2021) Vol 53, No 2 (2021) Vol 53, No 1 (2021) Vol 52, No 3 (2020): Special Issue: COVID-19 Vol 52, No 4 (2020) Vol 52, No 3 (2020) Vol 52, No 2 (2020) Vol 52, No 1 (2020) Vol 51, No 4 (2019) Vol 51, No 3 (2019) Vol 51, No 2 (2019) Vol 51, No 1 (2019) Vol 50, No 4 (2018) Vol 50, No 3 (2018) Vol 50, No 2 (2018) Vol 50, No 1 (2018) Vol 50, No 1 (2018): SUPPLEMENT Vol 49, No 4 (2017) Vol 49, No 3 (2017) Vol 49, No 2 (2017) Vol 49, No 1 (2017) Vol 48, No 4 (2016): SUPPLEMENT Vol 48, No 4 (2016) Vol 48, No 3 (2016) Vol 48, No 2 (2016) Vol 48, No 1 (2016) Vol 47, No 01 (2015) Vol 47, No 4 (2015) Vol 47, No 3 (2015) Vol 47, No 2 (2015) Vol 46, No 04 (2014) Vol 46, No 04 (2014) Vol 46, No 03 (2014) Vol 46, No 03 (2014) Vol 46, No 02 (2014) Vol 46, No 02 (2014) Vol 46, No 01 (2014) Vol 46, No 01 (2014) Vol 45, No 04 (2013) Vol 45, No 04 (2013) Vol 45, No 03 (2013) Vol 45, No 03 (2013) Vol 45, No 02 (2013) Vol 45, No 02 (2013) Vol 45, No 01 (2013) Vol 45, No 01 (2013) Vol 44, No 02 (2012) Vol 44, No 02 (2012) Vol 44, No 01 (2012) Vol 44, No 01 (2012) Vol 43, No 02 (2011) Vol 43, No 02 (2011) Vol 43, No 01 (2011) Vol 43, No 01 (2011) Vol 42, No 01 (2010) Vol 42, No 01 (2010) Vol 41, No 04 (2009) Vol 41, No 04 (2009) Vol 41, No 03 (2009) Vol 41, No 03 (2009) Vol 41, No 02 (2009) Vol 41, No 02 (2009) Vol 41, No 01 (2009) Vol 41, No 01 (2009) Vol 40, No 04 (2008) Vol 40, No 04 (2008) Vol 40, No 03 (2008) Vol 40, No 03 (2008) Vol 40, No 02 (2008) Vol 40, No 02 (2008) Vol 40, No 01 (2008) Vol 40, No 01 (2008) Vol 39, No 04 (2007) Vol 39, No 04 (2007) Vol 39, No 03 (2007) Vol 39, No 03 (2007) Vol 39, No 02 (2007) Vol 39, No 02 (2007) Vol 39, No 01 (2007) Vol 39, No 01 (2007) Vol 38, No 04 (2006) Vol 38, No 01 (2006) Vol 37, No 04 (2005) Vol 37, No 04 (2005) Vol 37, No 03 (2005) Vol 37, No 03 (2005) Vol 37, No 02 (2005) Vol 37, No 02 (2005) Vol 37, No 01 (2005) Vol 37, No 01 (2005) Vol 36, No 4 (2004) Vol 36, No 4 (2004) Vol 36, No 3 (2004) Vol 36, No 3 (2004) Vol 36, No 2 (2004) Vol 36, No 2 (2004) Vol 36, No 1 (2004) Vol 36, No 1 (2004) Vol 35, No 4 (2003) Vol 35, No 4 (2003) Vol 35, No 3 (2003) Vol 35, No 3 (2003) Vol 35, No 2 (2003) Vol 35, No 2 (2003) Vol 34, No 04 (2002) Vol 34, No 04 (2002) Vol 34, No 03 (2002) Vol 34, No 03 (2002) Vol 34, No 02 (2002) Vol 34, No 02 (2002) Vol 34, No 01 (2002) Vol 34, No 01 (2002) Vol 33, No 04 (2001) Vol 33, No 04 (2001) Vol 33, No 03 (2001) Vol 33, No 03 (2001) Vol 33, No 02 (2001) Vol 33, No 02 (2001) Vol 31, No 04 (1999) Vol 31, No 04 (1999) Vol 31, No 03 (1999) Vol 31, No 03 (1999) Vol 31, No 02 (1999) Vol 31, No 02 (1999) Vol 31, No 01 (1999) Vol 31, No 01 (1999) Vol 30, No 03 (1998) Vol 30, No 03 (1998) Vol 30, No 02 (1998) Vol 30, No 02 (1998) Vol 30, No 01 (1998) Vol 30, No 01 (1998) Vol 29, No 04 (1997) Vol 29, No 04 (1997) Vol 29, No 03 (1997) Vol 29, No 03 (1997) Vol 29, No 02 (1997) Vol 29, No 02 (1997) Vol 29, No 01 (1997) Vol 29, No 01 (1997) Vol 28, No 04 (1996) Vol 28, No 04 (1996) Vol 28, No 03 (1996) Vol 28, No 03 (1996) Vol 28, No 02 (1996) Vol 28, No 02 (1996) Vol 28, No 01 (1996) Vol 28, No 01 (1996) Vol 27, No 04 (1995) Vol 27, No 04 (1995) Vol 27, No 03 (1995) Vol 27, No 03 (1995) Vol 27, No 02 (1995) Vol 27, No 02 (1995) Vol 27, No 01 (1995) Vol 27, No 01 (1995) Vol 26, No 03 (1994) Vol 26, No 03 (1994) Vol 26, No 02 (1994) Vol 26, No 02 (1994) Vol 26, No 01 (1994) Vol 26, No 01 (1994) Vol 25, No 04 (1993) Vol 25, No 04 (1993) Vol 25, No 03 (1993) Vol 25, No 03 (1993) Vol 25, No 02 (1993) Vol 25, No 02 (1993) Vol 25, No 01 (1993) Vol 25, No 01 (1993) Vol 24, No 04 (1992) Vol 24, No 04 (1992) Vol 24, No 03 (1992) Vol 24, No 03 (1992) Vol 24, No 02 (1992) Vol 24, No 02 (1992) Vol 24, No 01 (1992) Vol 24, No 01 (1992) Vol 23, No 04 (1991) Vol 23, No 04 (1991) Vol 23, No 03 (1991) Vol 23, No 03 (1991) Vol 23, No 02 (1991) Vol 23, No 02 (1991) Vol 23, No 01 (1991) Vol 23, No 01 (1991) Vol 22, No 04 (1990) Vol 22, No 04 (1990) Vol 22, No 03 (1990) Vol 22, No 03 (1990) Vol 22, No 02 (1990) Vol 22, No 02 (1990) Vol 22, No 01 (1990) Vol 22, No 01 (1990) Vol 21, No 04 (1989) Vol 21, No 04 (1989) Vol 21, No 03 (1989) Vol 21, No 03 (1989) Vol 21, No 02 (1989) Vol 21, No 02 (1989) Vol 21, No 01 (1989) Vol 21, No 01 (1989) Vol 20, No 04 (1988) Vol 20, No 04 (1988) Vol 20, No 03 (1988) Vol 20, No 03 (1988) Vol 20, No 02 (1988) Vol 20, No 02 (1988) Vol 20, No 01 (1988) Vol 20, No 01 (1988) Vol 19, No 04 (1987) Vol 19, No 04 (1987) Vol 19, No 03 (1987) Vol 19, No 03 (1987) Vol 19, No 02 (1987) Vol 19, No 02 (1987) Vol 19, No 01 (1987) Vol 19, No 01 (1987) Vol 18, No 04 (1986) Vol 18, No 04 (1986) Vol 18, No 03 (1986) Vol 18, No 03 (1986) Vol 18, No 02 (1986) Vol 18, No 02 (1986) Vol 18, No 01 (1986) Vol 18, No 01 (1986) Vol 17, No 03 (1985) Vol 17, No 03 (1985) Vol 17, No 02 (1985) Vol 17, No 02 (1985) Vol 17, No 01 (1985) Vol 17, No 01 (1985) Vol 16, No 04 (1984) Vol 16, No 04 (1984) Vol 16, No 02 (1984) Vol 16, No 02 (1984) Vol 16, No 01 (1984) Vol 16, No 01 (1984) Vol 15, No 03 (1983) Vol 15, No 03 (1983) Vol 15, No 02 (1983) Vol 15, No 02 (1983) Vol 13, No 04 (1981) Vol 13, No 04 (1981) Vol 13, No 03 (1981) Vol 13, No 03 (1981) Vol 13, No 02 (1981) Vol 13, No 02 (1981) Vol 13, No 01 (1981) Vol 13, No 01 (1981) Vol 12, No 04 (1980) Vol 12, No 04 (1980) Vol 12, No 03 (1980) Vol 12, No 03 (1980) Vol 12, No 02 (1980) Vol 12, No 02 (1980) Vol 12, No 01 (1980) Vol 12, No 01 (1980) Vol 10, No 04 (1978) Vol 10, No 04 (1978) Vol 10, No 03 (1978) Vol 10, No 03 (1978) Vol 10, No 02 (1978) Vol 10, No 02 (1978) Vol 10, No 01 (1978) Vol 10, No 01 (1978) Vol 9, No 04 (1977) Vol 9, No 04 (1977) Vol 9, No 03 (1977) Vol 9, No 03 (1977) Vol 9, No 02 (1977) Vol 9, No 02 (1977) Vol 9, No 01 (1977) Vol 9, No 01 (1977) Vol 8, No 04 (1976) Vol 8, No 04 (1976) Vol 8, No 03 (1976) Vol 8, No 03 (1976) Vol 8, No 02 (1976) Vol 8, No 02 (1976) Vol 8, No 01 (1976) Vol 8, No 01 (1976) Vol 7, No 04 (1975) Vol 7, No 04 (1975) Vol 7, No 03 (1975) Vol 7, No 03 (1975) Vol 7, No 02 (1975) Vol 7, No 02 (1975) Vol 7, No 01 (1975) Vol 7, No 01 (1975) Vol 6, No 04 (1974) Vol 6, No 04 (1974) Vol 6, No 03 (1974) Vol 6, No 03 (1974) Vol 6, No 02 (1974) Vol 6, No 02 (1974) Vol 6, No 01 (1974) Vol 6, No 01 (1974) Vol 5, No 04 (1973) Vol 5, No 04 (1973) Vol 5, No 03 (1973) Vol 5, No 03 (1973) Vol 5, No 02 (1973) Vol 5, No 02 (1973) Vol 5, No 01 (1973) Vol 5, No 01 (1973) More Issue