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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 46   47   48   49   50 
Retkulocyte production index in various anemia Setyawati, Setyawati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Reticulocyte production index (IPR) is used to determine the classification of functional anemia. More specific laboratory parameters are used in managing patient. There were some inappropriate of IPR correlation with the diagnosis of anemia in clinical practice.Objectives: The study was designed to know normal hematocrit in Sardjito General Hospital, to determine IPR in various anemia and to compare with standard IPR and final diagnosis in anemia. Methods: Observational study was done in patients with anemia who whole blood examination in uderwent Clinical Pathology Laboratory on January 2001 until May 2002. Reticulocyte and hematocrit examination were performed before treatment. Patients were followed until. The diagnosis of anemia was established based on the clinical manifestations and laboratory results. Normal mean calculated hematocrit was based on age and sex. IPR was calculated based on standard hematocrit (45%) and mean normal hema-tocrit.Results: The normal mean hematocrit in male, female, children and infant were 43%, 39%, 40% and 48%, respectively. There was significant difference between the 2 formulas. The concordance of IPR determination in hipoproliferative anemia and maturation defects were 100%, in hemolytic/hemorrhagic anemia and maturation defect was 23,5%. The IPR of hypoproliferative anemia and maturation defect anemia differed significantly with haemolytic/ hemorrhagic anemia. IPR determination using factual hematpcrit show a better correlation with classification of functional than using standard hematocrit of 45%.Conclusion: IPR determination based on normal calculated hematocrit mean gave more benefit in increasing the correlation with classification of functional anemia. IPR value showed inappropriate result in hemolytic/hemorhagic anemia probably due to comorbidities.Key words: IPR - functional clasification anemial - anemia - normal calculated hematocrit
Beberapa Segi Klinik Mengenai Bells Palsy di Bagian Neurologi Rumah Sakit Universitas Gadjah Mada Boedi Sarojo, Boedi Sarojo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 01 (1976)
Publisher : Universitas Gadjah Mada

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Abstract

Selama periode Januari 1975 sampai dengan Desember 1975 kami kumpulkan 39 penderita dengan paralise facialis perifir dari seluruh penderita baru 747 orang yang datang berobat ke Rumah Sakit Pugeran Bagian Neurologi Eakultas Kedokteran Universitas Gadjah Made. Mereka terdiri dari 27 pria (69,2%) dan 12 wanita (30,8%). Umur penderita berkisar antara 1 tahun sampai 60 tahun, dengan rata-rata terbanyak sekitar umur 20 — 40 tahun (58;9%).Dari 39 kasus paralise facialis perifir yang terkiimpul atau terseleksi terdapat 25 Bells palsy atau 64,1 %: Penyebab lain seperti hypertensi 5 orang ( = 12,8%), meningitis pada anak-anak sebanyak 3 orang (7,7%), otitis media 2 orang (5,1%), trauma 2 orang (5,1%), mastoiditis 1 orang (2,5%) dan tumor cerebri 1 orang (2,5%).Sisi wajah muka yang terkena paling banyak adalah sebelah kanan, yaitu sebesar 61,5%. Tempat lesi yang paling banyak terletak di daerah distal foramen stylomastoideum, yaitu sebesar 69,2%.Penderita Bells palsy yang diobati akan sembuh pada minggu ke 2 — 4. Penderita paralyse facialis perifir lain antara lain 3 orang untuk observasi hypertensi (kiriman dari Bagian Penyakit Dalam), 1 dengan postmeningitis (kiriman dari Bag. Kanak-kanak) dan 1 dengan tumor cerebri (kiriman dari Bagian Mata, dengan visus jelek tanpa bisa dikon-lcsi) tidak dapat kami ikuti mengingat mereka tidak kembali setelah minggu ke 4 tanpa alasan.Semua penderita kimi beri terapi antibiotika, prednison, nicotinamide, vitamin neurotropik, dan beberapa ada yang kami beri salyci:ar. Bagi yang ada faktor etiologisnya kami beri terapi kausal, kecuali untuk tumor cerebri kami tambahkan terapi simptomatis.Lokal pada wajah muka kami beri penyinaran dengan inframerah, massage ringan - stimulasi dengan arus faradis/galvnis, ini diberikan dap 2 hari sekali. Di rumah penderita melakukannya sendiri dengan mengompres air hangat dan massage ringan selama 5 — 10 menit 3 kali sehari, sedang untuk matanya diberi tetesan acid boric 3% dan memakai kacamata teduh apabila ingin keluar rumah.Dari sejumlah 39 penderita ternyata 25 orang (64,1 %) mengalami penyembuhan dalam 4 minggu pertama dan 32 orang (82,05%) mengalami sembuh sempurna. Kami tidak menjumpai kontraktur sebagai satu-satunya gejaia sisa (sequela) penyakit ini.Ditemukan 2 pria yang menderita Bells palsy untuk kedria kalinya, pada sisi yang bertentangan dengan yang terdahulu.
Cholesteatoma Canalis Auricularis Externa (Gehtirgangs-Cholesteatom) di Rumah Sakit Universitas Gadjah Mada Bagian Ilmu Penyakit Hidung Telinga Tenggorok Dalam Periode Tahun 1966-1970 I.B. Agung, I.B. Agung
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 02 (1973)
Publisher : Universitas Gadjah Mada

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Abstract

Kami beranggapan bahwa sangatlah riskan untuk bergerak dalam bidang psychosomatik tanpa persiapan yang matang dalam klinik. Untuk mencapai sukses dalam bidang psycho-analyse dan psycho-therapi, menurut kami tidak ada jalan lain dari pada selaiu mawas diri dalam menghadapi segala macam masaalah kehidupan, tanpa meninggalkan petunjuk-petunjuk yang dilatih untuk dihayatinya.Di bidang psychosomatik sang aku yang selalu mengikuti alam fikiran yang logis pada saat menghadapi masaalah-masaalah yang ternyata bertitik tolak pada sumber hidup, harus menyerahkan kedaulatannya pada Zat yang akhirnya memegang kekuasaan, kebijaksanaan, keadilan dan kebenaran.Psychosomatik yang mendasari jalan fikirannya pada petunjuk-petunjuk yang digali dari ilmu Ketuhanan merupakan jembatan yang kokoh antara ilmu kedokteran dan religi. Mudah dimengerti, kalau dengan demikian "geneeskunst" akan meningkat.Akhirnya kami berpendapat, bahwa Candra Jiwa Indonesia yang ternyata mampu memecahkan masaalah-masaalah yang rumit di bidang psychosomatik, perlu diselidiki lebih lanjut, untuk mengetahui sampai berapa jauh Candra Jiwa Indonesia mampu memecahkan masaalah-masaalah di bidang psychologi, pedagogi din ilmu sosial lainnya, yang hingga kini masih merupakan teka-teki.Kami mernpunyai keyakinan, bahwa masaalah-masaalah pendidikan yang masih merupakan duri yang tajam bagi pembangunan, akan terselesaikan dengan cepat, jika Candra Jiwa Indonesia diselidiki, kemudian dimengerti dan akhirnya dilaksanakan tanpa purbasangka.
Pentingnya Kedokteran Ekologis Anonim, Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Kedokteran - Ekologi
Perinatal Mortality in Twin Infants Triwibowo Soedjas, Triwibowo Soedjas
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Universitas Gadjah Mada

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Abstract

Ditinjau kembali berat badan lahir, nilai Apgar, cara persalinan dan kematian perinatal pada 186 bayi kembar yang lahir di Rumah Sakit Universitas Gadjah Mada, Yogyakarta, tahun 1977 sampai dengan tahun 1981,Mereka terdiri atas 80 bayi pertama dan 106 bayi kedua. Tigapuluh sembilan (21%) bayi lahir kurang bulan, 112 (60,2%) dengan berat badan lahir rendah dan 78 (42%) termasuk sebagai bayi kecil untuk masa kehamilan.Bayi kedua mempunyai nilai Apgar yang lebih rendah dibanding dengan bayi pertama. Demikian Pula presentasi kematian perinatal dan cara persalinan abnormal pada bayi kedua lebih banyak dibanding dengan bayi pertama.Key Words: twin infants - Apgar score - neonatal mortality - abnormal labour - Lubchenco curve
Herpes simplex virus infection. The roles of T4ymphocytes in host responses M. Cholis, M. Cholis
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 04 (1996)
Publisher : Universitas Gadjah Mada

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Abstract

T-lymphocytes are the most important component of the immune response to control recurrent infections. T-Iumphocytes of CD4+ and CD8 + recognize a variety of viral proteins and produce lymphokines with antiviral and immunomodulatory effects. Both CD4+ and CIDER- bearing T-cells can kill HSV infected host cells. The relation between specific T-cells responses and severity of HSV disease have not been consistently detected. Interaction between T-cells responses and HSV and host cells result in a dynamic state of latency. HSV has evolved special mechanisms for evasion of host immunity. Reactivation can result in recurrences with the implication of transmission and/or disease. Molecular definition of T-cell responses for HSV may lead to immunological intervention to prevent HSV disease. Impaired T-cell immunity should be considered as a risk factor for severe infections.Key words: herpes simplex - T-cell role - latency - immunocompromised - vaccine
Pengobatan Asthma Bronchiale Dan Pemakaian Corticosteroid Samekto Wibowo, Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 03 (1974)
Publisher : Universitas Gadjah Mada

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Abstract

Survai mengenai tempat perkembang-biakan nyamuk Aedes aegypti di Daerah Istimewa Yogyakarta telah dilakukan oleh Bagian Parasitologi Fakultas Kedokteran dan Fakultas Biologi Universitas Gadjah Mada pada tgl. 27 Maret sampai dengan 30 April 1973.Dari hasil survai ternyata bahwa nyamuk Aedes aegypti lebih banyak bersarang di kota daripada di pedesaan. Hampir 100% dari desa atau kampung di mana terdapat penderita suspect D. H. F. terbukti positip Aedes aegypti. Nyamuk ini kebanyakan berkembang biak dalam tempayan (di dalam rumah lebih banyak daripada di luar rumah) dan hanya sedikit di pot-pot bunga ataupun di lobang-/obang pohon; jadi tidak seperti sifat aselinya.Dengan laporan di atas ini diharapkan agar penanggulangan penyakit D. H. F., khususnya pemberantasan vektor Aedes aegypti dapat berhasil dengan memuaskan.
The management of hyperlipidemia Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 03 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In terest in hyperlipidemia is related to its role in atherogenesis. The connection between bloodcholesterollevels and varibus manifestations of coronary heart disease has long been apparent.However, proof that this connecton is causal has been more elusive. For particular subpopulations it has been demonstrated that lowering elevated cholesterol levels can lead to fewer coronary heart disease events; this provides strong evidence of a causal relationship which can furthermore be favourably influenced.The significant lipid element contributing of plaque formation appears to be low density lipoprotein cholesterol, but its derivation in plaques in quite complicated. Low density lipoprotein and possibly intermediate density lipoprotein, with a somewhat lower cholesterol content, are known to enter sub-in finial spaces directly and they may do so in association whit cellular migration. Locally produced endothelial-derived relaxing factor.Despite the massive study on the subject of lipids, atherogenesis and its complications, much of our therapeutic endeavour still relates to hypothesis rather than established facts based on observations in humans. Key Words: hyperlipidemia - lipoproteins diet - physical exercise - antilipidemic drugs
Teknik Pembuatan Sediaan Mikroskop Elektron Daryanto, Daryanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 02 (1980)
Publisher : Universitas Gadjah Mada

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Abstract

This article describe a practical method in making preparation of animal tissues for electron microscopy. This method has been carried out on rat tissue in the Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand.Problems in fixation, dehydration, infiltration, embedding, sectioning and cutting. and staining are discussed. The author emphasized the needs for doing tissue work with an electron microscope in tune with the development of histology in Indonesia.Key Words: electron microscope - practical methods in eletron microscopy - histochemistry - sectioning - fixation
Hypophosphatemia in lung disease. Is there any cause and effect relationship ? Barmawi Hisyam, Barmawi Hisyam
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 04 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

Many reports showed that hypophosphatemia is prevalent in patients of lung disease with respiratory failure. Correction for hypophosphatemia may improve respiratory capacity, hence, morbidity and mortality. Serum phosphate levels may reflect intracelluler phosphate pool. A decrease in intracellular phosphate may implicate muscular adenosine tri-phosphate (ATP) and red blood cell 2,3 di-phosphoglycerate (DPG) synthesis. Reduction in respiratory muscle ATP will reduce respiratory since ATP is the the source of energy for muscle contraction. Reduction in red blood cel 2,3 DPG will shift hemoglobin dissociation curve to the left that lead to the disturbance of oxygen extraction by the cells. Hypoxia may be resulted from those processes, therefore, recoils the poor capacity of the respiratory muscle. Underlying primary lung diseases may partly play a role in the genesis of hypophosphatemia. Drugs often used for the disease, such as corticosteroids, xathine identification and treatment of hypophosphatemia in lung disease with or without respiratory failure in order to improve morbidity and mortality of the patients.Keywords : hypophosphatemia - adenosine tri-phosphate - 2,3 di- phosphoglycerate - hypoxia – respiratory- failure 

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