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INDONESIA
Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
Evolusi Otak Primates T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 01 (1975)
Publisher : Universitas Gadjah Mada

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Abstract

Di seluruh ordo Primates kita lihat berbagai perubahan evolusioner dalam perilaku hewan itu yang mengandung makna yang penting. Pcnyesuaian diri tcrhadap kehidupan arboreal menghasilkan perkembangan ekor prchensil ataujdan perubahan adaptif tangan dan kaki serta alat-alat indera pelihat. Perubahan ke kehidupan terrestrial membutuhkan penyesuaian kembali mata dan pengaturan keseimbangan. Yang teramat penting adalah sikap orthograd dengan akibat-akibatriya yang bersegi banyak. Pembebasan anggota muka dan Ienyapnya ekor meninggalkan bekas-bekas pula pada struktur otak.Tidaklah cukup hanya menyelidiki bentuk luar otak saja dalam mempelajari evolusi. Tidak dapat dihindari kesimpulan bahwa segala adaptasi progressif yang sudah disebutkan itu melontarkan bayangannya pula pada struktur dalamnya. Tilncy (1928:993) rnalahan menyatakan bahwa «ciri-ciri permukaan sering memperdaya» dan bahwa «organisasi intern otak yang haliis bahkan dapat membantah kesimpulan yang didasarkan atas pendaahan pada permukaanKehidupan arboreal mengakibatkan terkorbankannya indera pembau dan peluasan indera pelihat. Maka kita lihatlah pengecilan rhincncephalon dan perkembangan lobus occipitalis, bertambah panjangnya decussatio oculomotorii, bertambah kecilnya arti colliculus superior dan membcsarnya nucleus olivaris. Akibat_yang tidak kurang pentingnya pula adalah prehensilitas dan differensiasi anggota tubuh yang diperlukan dalam kehidupan di pohon. Syarat-syarat ini tercermin dalam pembesaran pyramis, oliva inferior, nuclei sensorii dorsales, nuclei vestibulares, nuclei pontes, nuclei cerebellar-es dan hubungan interokular, serta merosotnya colliculi mesencephalon. Penglihatan stereoskopis_meinberi dasar yang baru dan lebih luas bagi kemahiran tangan, dan gerakan-gerakan trampil yang komplek in.i sclanjutnya membutuhkan - pusat-pusat. pengaturan dan - koordinasi yang lebih balk. Kinesthesis yang progressif tak dapat dielakkan dan hal ini kemudian memberi dasar-dasar baru pula bagi neokinesis. Dengan demikian kita berhadapan dengan reaksi rantai evolusi dan aneka warna faktor yang mengambil bagian dalam proses tersebut terjalin dengan rumit dalam suatu jaringan yang harmonis.
Larvicidal activities of Bacillus thuringiensis H-14 and Bacillus sphaericus 1593 against three species of mosquitoes of disease vectors in Java Sugeng Juwono Mardihusodo, Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 02 (1992)
Publisher : Universitas Gadjah Mada

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Abstract

Bacillus thuringiensis H-14 and Bac. sphaericus 1593 are quite promising as biological control agents utilized as alternatives of chemical insecticides in controlling mosquitoes of disease vectors.The present studies are aimed at determining the larvicidal activities•of Bac. thuringiensis H-14 and Bac. sphaericus 1593 against Aedes aegypti, Culex quinquefasciatus and Anopheles aconitus, respectively recorded as the main vectors of dengue haemorrhagic fever, bancroftian filariasis and Malaria in Java.Two types of primary powder of Bac. thuringiensis H-14 (IPS 82) and Bac. sphaericus 1593 (RB 80) were tested on their respective activities against larval stages of the three species of mosquitoes under laboratory conditions.It was concluded that, ranked from the high to low level, Bac. thuringiensis H-14 was larvicidal to Ae. aegypti, Cx. quinquefasciatus and An. aconitus, whereas B. sphaericus 1593 was larvicidal to Cx. quinquefasciatus, An. aconitus and Ae. aegypti mosquitoes.Key Words: Bacillus thuringiensis H-14 - Bacillus spaericus 1593 - Aedes aegypti - Culex quinquefasciatus - Anopheles aconitus
Teknologi Pada Pendidikan Kedokteran Di Indonesia M. Ismadi, M. Ismadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 04 (1980)
Publisher : Universitas Gadjah Mada

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Abstract

Keyword : Teknologi Pendidikan Kedokteran
Livedo reticularis in a patients with Wegener Granulomatosis. A case report. Elly Moedijatmini, Elly Moedijatmini
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Livedo reticularis (LR) is a skin lesion which is characterized by a reddish blue mottling in a fishnet reticular pattern. Although many diseases have been considered as causative of LR, Wegeners Granulomatosis (WG) has never been reported to be associated with LR.A case of LR was reported in a 70-year-old woman suffering from WG. However, it is difficult to conclude whether LR is a part of WG or only a coincident case. The vasculitis features as shown by histopathological skin examination suggest that the skin lesion might be a part of WG syndrome.Key words : livedoreticularis - Wegener granulomatosis - saddle nose - skin biopsy - vasculitis granulomatosis
Societal attidude toward diarrhoeal diseases and bacteriological lest results of faeces in Yogyakarta Trihendrokesowo, Trihendrokesowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 01 (1987)
Publisher : Universitas Gadjah Mada

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Abstract

Nine-hundred eighty eight diarrhoeal disease patients of general hospitals, Public Health services and physicians in Yogyakarta during the period of January to October 1985 have been investigated. The results indicated that 75.20% of the patients were suffering diarrhoea of more than one day, and 83.10% with more than three times diarrhoea frequency in one day. In addition to diarrhoea symptoms, in more than 50% patients they were accompanied by abdominal pain and fever. Four point two percent of the patients received electrolyte and sugar solution before treatment. Examinations of faecal materials uncovered the presence of various bacteria suspected to be the causative agents of diarrhoea] diseases namely Vibrio parahaemolyticu.s, Vibrio choleree, Shigella flexneri, Salmonella enteritidis and E. coll. Key Words: diarrhoea] disease — abdominal pain — fever -- electrolyte solution — bacteriology
Multiple Sclerosis in the Tropics: four Additional Cases Harsono, Harsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 02 (1990)
Publisher : Universitas Gadjah Mada

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Abstract

Multiple sclerosis merupakan penyakit yang bersifat kronis progresif, yang dalam perjalanan kliniknya dicirikan oleh sifat yang khas, yaitu remisi dan eksaserbasi. Sampai dengan saat ini multiple sclerosis masih dianggap sebagai suatu penyakit auto-imun atau suatu penyaldtyang disebabkan oleh infeksi virus.Prevalensi multiple sclerosis di Indonesia belum diketahui. Pada umumnya prevalensi multiple sclerosis di negara-negara Asia sangatrendah, kurang dari 5 per 100 000; bahkan ada anggapan bahwa multiple sclerosis tidak diremukan di negara tropic.Dilaporkan empat kasus multiple sclerosis yang ditemukan di Daerah Istimewa Yogyakarta dalam kurun waktu 9 tahun terakhir. Di Indonesia laporan kasus ini merupakan laporan yang kedua. Pada tahun 1987 untuk pertama kali telah dilaporkan 3 kasus multiple sclerosis yang dirawat di RSUP Dr. Soetomo, Surabaya.Key Words: multiple sclerosis - atuoimmune disease - echovirus type II - latitude and disease -Schumacher criteria
Impek sosial dan resosialisasi penderita kejang R. Soejono Prawirohardjo, R. Soejono Prawirohardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 02 (1978)
Publisher : Universitas Gadjah Mada

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Abstract

Keyword : penderita kejang
Microplate assay analysis of potential for organophosphate insecticide resistanse in Aedes aegypti in the Yogyakarta Municipality, Indonesia. Sugeng Juwono Mardihusodo, Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 02 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Sejak tahun 1970-an insektisida organofosfat (OP), temefos dan malathion, digunakan dalam program nasional pengendalian wabah demam berdarah Dengue di Indonesia, yang vektor utamanya adalah nyamuk Aedes aegypti. Dalam kurun waktu yang sama kedua senyawa OP itu diketahui menimbulkan resistensi pada Ae. aegypti stadium dewasa dan larva di Malaysia. Timbul dugaan bahwa Ae. aegypti stadium larva dan dewasa di Kodya Yogyakarta juga telah resisten terhadap kedua senyawa OP tersebut. Penelitian ini bertujuan untuk menetapkan status kerentanan Ae. aegypti stadium larva di Kodya Yogyakarta terhadap temefos dan malathion, dan mengetahui potensinya untuk menjadi resisten terhadap insektisida OP dibandingkan dengan populasi Ae. aegypti hasil kolonisasi di insektarium. Cara penelitian meliputi penggunaan uji mikroplat untuk peningkatan aktivitas enzim esterase non-spesifik pada Ae. aegypti stadium larva, diperkuat dengan uji hayati terhadap malathion dan temefos. Dari analisis data hasil penelitian tersebut disimpulkan, bahwa Ae. aegypti di Kodya Yogyakarta, stadium larvanya berkesan mulai resisten terhadap malathion dan temefos. Hal ini berbeda nyata dari Ae. aegypti stadium larva hasil kolonisasi insektarium yang masih sangat rentan terhadap kedua insektisida OP tersebut. Ae. aegypti di Kodya Yogyakarta berpotensi untuk menjadi resisten terhadap insektisida OP.Key Words : biochemical test -- malathion -- temephos -- insecticide resistance -- Aedes aegypti
Diagnosis Radiologis Enterocolitis Necroticans Soeroyo, Soeroyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 20, No 04 (1988)
Publisher : Universitas Gadjah Mada

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Abstract

Necrotizing enterocolitis (NEC) is a multifactorial disease with an unknown pathogenesis. NEC has a high Mortality rate and incidence is predominant in premature with stress.NEC shows characteristic signs of the ischemic necrosis of the intestine, which can be detected on X-ray picture.X-ray examination would be more useful for detecting NEC in an early stage, following the pro cess and for the reopening of the stricture of the intestine.Key Words: necrotizing enterocolitis (NEC) - ischemic necrosis - radiology - neonatology -prematurity
Correlation between leptin level with lipid profile and free fatty acid in liver cirrhosis patients Siti Nurdjanah, Siti Maryani, Neneng Ratnasari,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 03 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/jms.v46i03.7308

Abstract

Malnutrition is a common condition in liver cirrhotic patients. Leptin regulates body weightphysiologically by suppressing appetite and increasing energy expenditure. Leptin is higher in femalethan male. Studies have shown correlation between leptin with metabolic factors like body massindex (BMI) and lipid profile in cirrhotic patients. This study was conducted to investigate thecorrelation between serum leptin levels with lipid profile and free fatty acid in male patients with livercirrhosis. This was a cross sectional study that conducted at Gastroentero-Hepatology Clinic andInternal Ward at Dr. Sardjito General Hospital, Yogyakarta. The inclusion criteria were patients withliver cirrhosis > 18 years old, male, with Child-Pugh classification B and C, and provided informedconsent. The exclusion criteria were liver cirrhotic patients with comorbidity chronic kidney disease,chronic heart failure, diabetic, cancer, infection/septic, pregnancy, breast feeding, and steroid use.Data collecting was performed by anamnesis, physical examination, abdominal ultrasonographyexamination, and blood chemistry test. Pearson test was used to evaluate the correlation betweenthe serum leptin level with the lipid profile and free fatty acid. The results showed that no significantnegative correlation was observed between the serum leptin level with the total cholesterol (r= -0.052; p=0.766), high-density lipoprotein/HDL (r= -0.078; p=0.658) and triglyceride (r= -0.170; p=0.328) in male patients with liver cirrhosis. Furthermore, no significant positive correlationwas observed between the serum leptin levels with the low-density lipoprotein/LDL (r= -0.013; p=0.942) and free fatty acid/FFA (r= 0.007; p=0.968). In conclusion, there was no correlationbetween serum leptin levels with lipid profile and FFA in male patients with liver cirrhosis.

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