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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 95   96   97   98   99 
Rahasia Jenazah Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 01 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Jenazah
The Effects of new T cell line derived lymphokines on B cell activation Sofia Mubarika Haryana Sofia Mubarika Haryana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 01 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Telah diketahui bahwa untuk aktivasi limfosit B diperlukan faktor pertumbuhan yang disebut limfokin atau sitokin. Banyak bukti menunjukkan bahwa limfosit T yang teraktivasi menghasilkan substansi yang dapat memacu proliferasi atau diferensiasi limfosit B. Dewasa ini telah dapat diidentifikasi berbagai limfokin yang disebut sebagai interleukin (IL) seperti IL-2, IL-3, IL-4, IL-5, IL-6 dan IL-7 yang ikut berperan dalam aktivasi sel B. Namun, mekanisme aktivasi sel B oleh limfokin sampai sekarang masih terus berkembang dan dipelajari. Untuk dapat lebih memahami aktivasi sel B, dalam penelitian ini telah dilakukan pembuatan suatu T cell line, dan telah dikarakterisasi, yakni menunjukkan fenotipe Thyl+, Lyt1+2+, Dalam penelitian ini berbagai aktivator poliklonal lipopolysaccharide (LPS), ConA, dextran sulfat dipakai untuk memacu T cell line menghasilkan limfokin. Aktivitas limfokin pada supernatannya kemudian dianalisis dengan menggunakan blastogenesis assay dengan 3H-thymidine dan hemolytic plaque assay.Hash penelitian menunjukkan bahwa T cell line menghasilkan faktor pertumbuhan yang memacu proliferasi sel B (B cell growth factor II = BCGF II atau IL-5) dan faktor yang memacu sel B untuk berdiferensiasi (B cell differentiating factor = BCDF atau IL- 6) dan menghasilkan igM dan IgG.Key words : blastogenesis assay -- hemolitic plaque assay -- B cell activation -- T cell line -- lymphokines
Activity of -terpineol as a potential anticancer candidate: cytotoxicity, proapoptotic and antiproliferative evaluation in TD47 cell lines Puguh Indrasetiawan Indwiani Astuti Mustofa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Previous study has shown that -terpineol has a cytotoxic effect on NCI-H69 cancer cell line.This study aimed to evaluate cytotoxicity, proapoptotic, and antiproliferative activities of -terpineol in T47D cell lines. The cytotoxic activity of -terpineol was determined using MTT cellviability assay, while apoptosis was tested by the acridine orange-ethidium bromide stainingmethod. The cell cycle was evaluated by flowcytometry method. The results showed that -terpineol had cytotoxic effect on the T47D cells with the IC50 value of 135.00 ± 8.74 M.Furthermore, -terpineol induced the cells apoptosis in a dose-dependent manner. Flowcytometryanalysis showed that -terpineol induced the T47D cell distribution in Go/G1 phase, howeverinhibited cell distribution in S phase. This study suggests that -terpineol has a potential anticanceractivity.
Hubungan Sistem Lymphe Dan Vena Pada Bagian Superficial Jantung Djaka Prakosa Djaka Prakosa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 02 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

18 cow hearts have been studied to demonstrate the existence of communications between lymph vessels and veins on the superficial surface of the heart. The findings showed that in 9 cases such communications could be demonstrated, being 1 or 2 in number on each heart. Most of them were located on the sternocostal surface, especially near the apex.The diameters of the lymph vessels near the communications were found to be 80 to 480 microns.These anastomosis were assumed to play a role in certain conditions such as in lymphatic or venous stasis.
Polusi - bising Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 01 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci : Polusi - bising
A comparison study on the blood transfusion reaction between the elective and the emergency operation’s patients Hidayati Samsiarah Ishandono Dachlan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 43, No 02 (2011)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Blood transfusion is principally a process of transferring blood or blood components from one individual (the donor) toanother individual (the recipient). Blood transfusion can be either a life saving condition or a life threatening situation dueto the complications happened. Therefore, blood transfusion should be conducted with clear and accurate indication inorder to obtain a condition in which the advantages outweighs the disadvantages. The aim of this study was to evaluatethe differences of the blood transfusion reactions between the patients underwent the emergency surgery with theelective surgery. This was a cross sectional study using data from the medical records from January to December 2009and from the observation on blood transfusion patients from January to May 2010. Data were analyzed using independentt-test, Chi-square test or the logistic regression, with 95% confidence interval (p<0.05). Two hundred and sixty eightdata from medical records and directly observation on blood transfusion patients were obtained during the study. Thewere significant differences of patient reactions after blood transfusion on both types of operation and blood componentstransferred (p<0.05).The transfusion reactions were more frequent in emergency surgery (54.9%) compared withelective surgery (30.5%). Based on types of blood component transfered, the transfusion reaction was more frequentafter Whole Blood/WB transfusion (84.9%) compared with Packed Red Cell/PRC transfusion (25.1%) and Fresh FrozenPlasma/FFP transfusion (25%). The types of operation and blood products had been proven to be the risk factors in bloodtransfusion. Moreover the blood products contributed more in the transfusion reactions compared with the types ofoperation (p<0.05). Amount of transfused blood based on haemoglobin correction formula on both the emergency orelective operations was not significantly different (p>0.05). In conclusion, blood transfusion reactions happened morefrequently in emergency surgery than elective surgery. The WB also generated transfusion reaction more frequently thanthe PRC. The amount of blood required based on hemoglobin correction formula for most patients was similar to the bloodtransfused.Key words: blood transfusion-type of operation-transfusion reaction - whole blood-haemoboglobin correction formula
The effect of oral indomethacin on the incidence of cystoid macular edema after cataract surgery with implantation of an intraocular lens. Suhardjo Suhardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 01 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Cystoid macular edema after cataract extraction with implantation of an intraocular lens is considered to be the most frequent and troublesome complication. The advantage of topical indomethacin had been previously proven, but the influence of oral administration had not been investigated. The purpose of this study is to Investigate the effect of the using of indomethacin on the incidence of cystoid macular edema after cataract surgery with an intraocular lens implantation. Two groups of patients with matured and immatured senile cataract undergone extracapsular cataract extraction with implantation of an intra ocular lens had been reported. Each group consisted of 40 patients. Indomethacin group received 25 mg indomethacin orally 2 hours preoperativelly, as well as at 2, 6, and 10 hours postoperativelly then continued for 5 days postoperativelly. Ocular examinations were performed on postoperative days 1, 3, 7, 14, 28, 60, and 90. No Incidence of cystoid macular edema in group indomethacin was found and in placebo group was 2,5% (x2 = 0,001; p> 0,05). After seven days observation on the effect of indomethacin to the postoperative inflammatory reaction demonstrated that there was insignificantly difference between indomethacin and placebo group (x2 = 2,15; p >0,05). Observation on the therapeutic side effect phenomenon indicated that Indomethacin was relativelly safe even if used in the aged patients.Key Words : oral indomethacin - cystoid macular edema - cataract operation - intra-ocular lens -inflammatory reaction
Obstetric care and the prevention of blindness Soeprono Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Blindness, affecting multidimensionally the lives of the individual, his family and the society, has been known according to the 1980 Indonesian Population Census to prevail for 22.1% with children and for 77.9% with adults. Based on this fact, causative factors as genetic aberrations, infectious diseases and malnutrition, drugs and radiation, birth traumas and hypertensive diseases ought to be eliminated by all possible measures, e. g. adequate obstetric care starting from the pre-conceptional period, during pregnancy, delivery and in early childhood, by a more healthy pattern of living and nutrition, and a bigger sense of responsibility on the part of both parents. It is thought to be appropriate to base laws and regulations governing social, medical and educational rehabilitation and aid programs on more Adequate medical and functional criteria to better benefit the visually handicapped. Key Words: blindness - obstetric care - genetic diseases - malnutrition - congenital disorders
Minimum Incidence Kanker Had Primer di Yogyakarta Soeripto Soeripto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 01 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

There is a tendency of primary liver cancer between 1970-1973 corresponding to the introduction of liver biopsy in Yogyakarta. Liver cancer had previously been found to be the most frequent tumour in necropsy material in Java. In the series, composed of biopsies only, it accounted for 36.8% of all abdominal cancers biopsied in Yogyakarta in 1973 and is thus more frequent than indicated by the total material covering a 4-year period (1970-1973).Based on the data of the Department of Pathology and population in 1976 by utilizing the formulathe primary liver cancer incidence in 1974 through 1978 is provided.It seems that the minimum incidence of primary liver cancer in Yogyakarta is lower than the incidence in other countries in Asia and AfricaKey Words: liver cancer - cancer registration -incidence of hepatoma - racial predisposition for cancer - viral hepatitis
Determinants of immunization coverage in Yogyakarta Province Syarifah Hanum Syarifah Hanum
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Children and infant immunization are often viewed as the symbol of preventive medicine and health service. Furthermore, immunization coverage is often used as an indicator of health service achievement. Recognizing the determinants associated with infant and children immunization status is one of the efforts to increase immunization coverage.Objectives: To know the immunization coverage in Yogyakarta province and determinants associated with coverage and age on immunization.Materials and methods: This is a cross-sectional study on children 12-23 months of age living in Yogyakarta municipality and other four districts in Yogyakarta province. Subjects were selected using proportional probability multistage cluster random sampling from 30 clusters each representing rural and municipality as urban area.Results: The coverage in municipality as well as in urban areas exceed 90%. The coverge is too high to allow analysis on unimmunized children. We found no statistically significant difference of coverage between rural educational level and though there was a significant difference in parental educational level and occupation distance to nearest health center and age on immunization (p>0.05). There is a statistically significant difference between age on BCG and hepatitis B immunization with place of immunization (p<0.05).Conclusion: Immunization coverage in Yogyakarta province based on survey exceeded 90%. Determinant associated with age on immunization was place of immunization.Key words: immunization coverage - determinant - age on immunization. 

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