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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
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Search results for , issue "Vol 3 No 3 (2015)" : 30 Documents clear
Formulasi dan Penentuan Stress Testing Sediaan Krim M/A dan A/M Ekstrak Etanol Edamame (Glycine max) (Formulation and Stress Testing of Ethanol Extract Edamame (Glycine max) O/W and W/O Cream) Oktavia Catur Xenograf; Budipratiwi Wisudyaningsih; Siti Muslichah; Moch. Amrun Hidayat
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Edamame is a species of soybean (Glycine max) that contains isoflavone which has tyrosinase inhibitory activity. The aims of this study were to determine the effect of formulation on genistein content and the effect of storage temperature (25 °C and 50 °C) on oil in water (o/w) and water in oil (w/o) cream physicochemical characteristics (viscosity, spreadability, and pH). Genistein level was determined using thin layer chromatography (TLC) densitometry method and stability test was determined using stress testing method. The result showed that formulation gave no effect on genistein content in o/w and w/o cream with recovery values of 95.4178 ± 2.2815 % and 101.8276 ± 5.0063 %, respectively. The storage at 25 °C gave no effect on physicochemical characteristic, while the storage at 50 °C decreased viscosity value and increased spreadability value of cream.   Keywords: edamame, isoflavone, cream, stress testing
Motivasi Perawat dalam Pemenuhan Kebutuhan Spiritual pada Klien di Ruang Rawat Inap Rumah Sakit Daerah Balung (Nurses Motivation to Patients Spiritual Needs Fulfillment at Balung Hospital) Ahmat Robbi Tricahyono; Retno Purwandari; Mulia Hakam
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Nursing care is done by considering individuals as the holistic (bio-psycho-socio-spiritual) creature, particularly in fulfilling spiritual needs. This research was intended to analyze the relationship between the nurses motivation and patients spiritual needs fulfillment at Balung Hospital. This research applied observational analytic method with cross sectional. Sampling technique used total sampling by involving 48 respondents. Data was analyzed using nonparametric Chi Square. The result of the analysis reveal that the majority of the motivation of the nurses was influenced by extrinsic motivation, 72,7% of high motivation and good spiritual fulfillment, 38,5% of low motivation was good spiritual fulfillment, 61,5% of low motivation was bad spiritual fulfillment, and 27,3% of high motivation was bad spiritual fulfillment. Results of statistical analysis showed that the p-value is 0,037 (α=0,05) which indicates the relationship between nurses motivation and spiritual needs fulfillment to patients at Balung Hospital. Fulfilling spiritual needs is an important aspect in the process of treating the clients. It is the nurse’s duties to observe then fulfill the patients spiritual needs. Hence, coordination with other medical team through various discussions is an immediate importance. Nurses are expected to meet the patients needs of spiritual aspects in order to achieve a more holistic nursing care.   Keywords: nursing care, motivation, spiritual fulfillment
Effect of Disinfection with Spraying Technique 35 % Betel Pepper leaf boiling water and 0,5 % Sodium Hypochlorite on Dimensional Stability of Casts Made from Alginate Durrotul Lamiah; R Rahardyan Parnaadji; Agus Sumono
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Alginate is an impression matter that often used on dentistry. Some studies showed that aginate caused cross infection. it needs a disinfection product to avoid that cross infection. the disinfection matter which often used are betel pepper leaf boiling water and the sodium hypochlorite, but alginate have imbibition characteristic and fenol that contain in betel pepper leaf boiling water suggested dimensional changes on alginate. The technique of this research with sprayed technique. The aim of this research’s to find dimentional stability on casts made from alginateafter disinfection procedure with sprayed technique used 35 % betel pepper leaf boiling water and 0,5 % sodium hypochlorite. This research is an experimental laboratories using post test only control group design. The samples are an upper jaw replica. The samples are 28 samples and divided into 4 groups. A group is directly filling and the others are sprayed with aquadest sterile, 35 % betel pepper leaf boiling water and 0,5 % sodium hypochlorite and saved in vacuum box for 10 minutes. Samples measured by term mizzen with 0,05 accuracy.The conclusion of this research is there was dimentional changes on casts made from alginate after disinfection procedure with sprayed technique used 35 % betel pepper leaf boiling water and 0,5 % sodium hypochlorite.  Keywords: Alginate, betel pepper leaf, cross infection, dimensional stability, sodium hypochlorite.
Pengaruh Lama Pemberian Distres Kronis terhadap Aktivitas Sel Osteoklas pada Tulang Alveolar Tikus Sprague-Dawley (The Effect of Chronic Distress Duration to Osteoclast Cells Activity in Alveolar Bone of Sprague-Dawley Rats) Maria Devitha; Didin Erma Indahyani; Happy Harmono
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Excessive and prolonged distress (chronic) can cause damage to periodontal tissues, specifically alveolar bone resorption. Alveolar bone resorption is caused by osteoclast cells activity. The purpose of the research is to determine effect of chronic distress duration to osteoclast cells activity in alveolar bone of male Sprague-Dawley rats attain the age of 3-4 months. The rats were given an electric shock stressor (Electrical Foot Shock) as distress chronic for 7, 14, and 28 days. Stressors were given for 30 minutes at 9 a.m every day during the treatment period. The amount of electrical current is 2-8 mA, 48 V voltages and 0.5 Hz frequency. Osteoclasts activity were observed histologically with 400x magnification using osteoclast Bone Interface (OBI) Index by dividing the length of howship's lacunae with osteoclasts. Result showed signifficant difference at 0.00 (p<0.05) beetwen the variable.Activity of osteoclasts in alveolar bone of Sprague-Dawley rats which were exposed to the stressor is increased when compared to the group that were not exposed to electrical shock stressor, but at day 14 decreased when compared to the other treatment groups. Keyword : chronic distress, osteoclast activity, alveolar bone
Efek Angiogenesis Beraprost terhadap Gambaran Histopatologi Jantung Tikus Galur Wistar Hipertensi (Angiogenesis Effect of Beraprost on the Cardiac Histopathology of Hypertensive Wistar Rat) Cynthia Damayanti; Suryono Suryono; Arief Suseno
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hypertension is a state where there is an increase of blood pressure above normal threshold,120/80 mmHg. The phatophysiology of hypertension involves the changes of vascular structure. Therefore, the beraprost drug was created. It is a vasodilator and antitrombolytic which is able to induce angiogenesis. The study aimed to investigate the effect of Beraprost on angiogenesis as a hypertension therapy agent. In true experimental design, 22 males wistar rat were divided into control group and treatment group (Beraprost 100mcg/KgBW/day). The results showed that the systolic blood pressure decrease after therapy with Beraprost from 180 mmHg to 143 mmHg whereas diastolic blood pressure consistant at 80 mmHg after induction of hypertension as well as therapy of Beraprost. An examination of cardiac histopathology, there was an increasing number of blood vessels in the treatment group, 16.637.29 compared to 7.45 1.21 in control group. It can be concluded that Beraprost had an angiogenesis effect and decrease systolic blood pressure in hypertensive rat model. Keyword : Hypertension, Beraprost, vascular structure, angiogenesis.
Intensi Orang Tua dalam Pengambilan Keputusan untuk Menikahkan Anak Perempuan di Bawah Usia 20 Tahun di Kecamatan Pakem Kabupaten Bondowoso (Parents Intention in Decision Making to Wed Their Under 20 Years Old Daughter in Pakem, Bondowoso Regency) Riski Anisa; Andrei Ramani; Irma Prasetyowati
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Early marriage is a marriage which is conducted before the age of 20th. Early married girl hasmore risk in reproductive health and mortality. Bondowoso Regency has the highest of earlymarriage rates 52,93% from the marriage total in 2012. Pakem Subdistrict in BondowosoRegency has the highest rate for marriage under 20 years. In 2013, Pakem Subdistrict inBondowoso Regency has the higest rate of early marriage rates 53,18% and in 2014, earlymarriage rates 67,02%%. This study aimed to identify factors of parents intention on under20 years old girls marriage in Pakem, Bondowoso Regency. This study based on the Theoryof Planned Behavior with cross-sectional design. The respondent were parents which have10-19 years old daughter not married yet. Spearman correlation test applied to determineassociations between each variable. Result showed that knowledge significantly associatedwith attitude (p=0,000), subjective norm (p=0,008), and behavioural control (p=0,000).Income rate of parents was not significantly associated with attitude (p=0,106), subjectivenorm (p=0,951), and behavioural control (p=0,564). Education significantly associated withattitude (p=0,000), subjective norm (p=0,007), and behavioural control (p=0,035). Attitude(p=0,001), subjective norm (0,001), and behavior control (0,000) were significantly associatedwith parents intention.Keywords: early marriage, intention, attitude, subjective norm, behavioral control
Efektivitas Penggunaan Insulin pada Penderita Diabetes Melitus dengan Kehamilan di Rawat Inap RSD dr. Soebandi Jember Tahun 2012-2013 (Effectivity of Insulin Usage on Diabetic Mellitus Gestational Hospitalized Patient at RSD dr. Soebandi Jember in 2012-20 Riza Rastri Wihardiyanti; Prihwanto Budi Subagio; Fifteen Aprila Fajrin
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Gestational diabetes melitus is a diseases that are frequently happen to pregnant women, and is happen to be one of the causes of mortality on mother and fetus. The use of drugs during pregnancy should be prudentially considered for pregnant women, since they are not allowed to consume anti-diabetic drug (OAD) and just allowed to use insulin as therapy. The purpose of this study was to describe the use of insulin, as well as assessing the effectiveness of insulin therapy in patients with gestational diabetes mellitus in RSD dr. Soebandi Jember. The sample in this study was taken from 23 patients. We found that the disease affect 7.69% patients of 20-24 years of age, 11.54% patients of 25-29 years of age, 26.92% patients of 30-34 years of age, 30.77% patients of 35-39 years of age, 7.69% patients of 40-44 years of age and 15.38% patients of above 45 years of age. The insulin used in the sampling is Actrapid for 10 patients and Novorapid for 4 patients. It is known that the effectiveness of insulin based on blood glucose random levels with insulin Actrapid and Novorapid in sub-cutaneous do not have significant differences. Keywords: diabetic mellitus gestational, insulin, antidiabetic drugs
Hubungan Motivasi Perawat dengan Pelaksanaan Prinsip 12 Benar dalam Pemberian Obat di Ruang Rawat Inap RSU dr. H. Koesnadi Bondowoso (The Correlation between Nurses’ Motivation with the Implementation of 12 Principles of Right in Medicine Giving in Inpat Retno Utami; Dodi Wijaya; Iis Rahmawati
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Nurse is the most appropriate medical staff to give medicine and vacate their time for the patients. In giving medicine, nurse also must concern on the given prescription must be appropriate, the exact qualification of dosis that is given and always applying 12 principles right away. This condition might cause the occurrence of interaction between the characteristic of a nurse that is her motivation and his work. The purpose of the research is to analyze the relation of nurse’s motivation and applied of 12 principles of right in giving medicine in inpatient wards of dr. H. Koesnadi hospital in Bondowoso. The design of this research that is used is observational analysis with cross sectional and sample approach used 51 correspondences. Data collection technique is sample probability with simply random sampling. The result of the data analysis used chi square test. The result show that P value 0.005 (0.005< α=0.05) means that there is relation between nurse’s motivation and the applies 12 principles of right in giving medicines having this research, hopefully for the institution of the hospital for increase even more the nurse’s motivation in working by giving reward and punishment to the nurses and give them special seminar related to 12 principles of right in giving medicines.   Keywords: nurse’s motivation, 12 principles of right in giving medicines, inpatient wards
Daya Antibakteri Fraksi n-butanol Kulit Buah Delima Putih (Granati fructus cortex) terhadap Streptococcus mutans (Antibacterial Activity of White Pomegranate Pericarp (Granati fructus cortex) n-butanol Fraction against Streptococcus mutans) Gea Akalili abrina; Sukanto .; Niken Probosari
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Pomegranate white pericarp contains flavonoids, tannins and phenols which are antibacterial. These compounds are soluble in n-butanol fraction. Streptococcus mutans (S. mutans) is normal bacteria of oral that can be pathogenic and cariogenic, so this should be inhibited bacterial growth. This research was aimed to determine whether n-butanol fraction of pomegranate pericarp had antibacterial activity against S. mutans and how much the most effective concentration in inhibiting growth and done in vitro. Possibility of n-butanol fraction pomegranate pericarp could inhibit growth of S. mutans. The method used was a pour plate using a serial dilution methods with a concentration of 0,313% up to 10%. Kruskal Wallis and Mann Whitney test showed significant difference between groups with p=0.000 (p< 0.05). In conclusion, namely n-butanol fraction of pomegranate pericarp had antibacterial activity against S. mutans and the most effective concentration of the antibacterial concentration was 10%. Suggestions for further research for role of compounds in pomegranate pericarp that inhibit the growth of S. mutans. Keywords: n-butanol fraction, S. mutans, White pomegranate pericarp
Optimasi Konsentrasi Kitosan dan Lama Pengadukan dalam Preparasi Microspheres Metformin Hidroklorida (Optimization of Chitosan Consentration and Stirring Time on Preparation of Metformin Hydrochloride Microspheres) Tintia Lintang Pratiwi; Eka Deddy Irawan; Lusia Oktora Ruma Kumala Sari
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Microspheres is multiple dosage unit controlled drug delivery system with the range of a particle size of 1-1000 µm. Chitosan was used as a polymer and metformin hydrochloride (MH) was used as a drug, and non-aqueous solvent evaporation was chosen for the techniques of microspheres preparation. MH is the first line for treatment of diabetes mellitus type 2. It has relatively low bioavailability and short half-life, therefore it is appropriate to be prepared as microspheres. Many factors affect the result of microspheres preparation, such as chitosan concentration and stirring time which used in preparation. Factorial design optimization used to determine the chitosan concentration and stirring time to produce MH-chitosan microspheres with the highest entrapment efficiency (EE). The result of microspheres preparation used 2250 mg of chitosan and 2 hours stirring time produced 81.191 % EE, and drug loading and yield of 22.673 and 89.602 %, respectively. The microspheres had spheres shape and a relatively smooth and bright surface morphology. The particle size was 653.333 μm. FT-IR analysis indicated that there were no changes in the functional groups on MH as an active ingredient.   Keywords: metformin hydrochloride-chitosan microspheres, non-aquoeous solvent evaporation, factorial design, chitosan concentration, time stirring

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