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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
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Search results for , issue "Vol 6 No 2 (2018)" : 30 Documents clear
Efektivitas Ekstrak Artemisia vulgaris L. sebagai Hepatoprotektor pada sel-sel Hati Tikus yang Diinduksi Niasin Laily Rahmawati; Erma Sulistyaningsih; Rosita Dewi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7617

Abstract

The niacin in energy drinks has metabolic product that cause oxidative stress and liver damage, while the liver damage can be prevented by hepatoprotective agents. Scoparone in Artemisia vulgaris L. can act as a hepatoprotector by its antioxidant effect. This study aimed to investigate the effectivity of Artemisia vulgaris L. extract as a hepatoprotector in wistar hepatocytes induced by niacin. This study used 25 male rats which were divided into 5 groups: normal, the negative control, the positive control, the treatment group I, and II. Treatment was conducted for 28 days. The samples were terminated and the hepatocyte were prepared for histological examination. Histological appearance was catagorized as mild, moderate, and severe damage with or without inflamatory cells activity. The data analysis by Kruskal Wallis showed significant difference (p<0,001). Further analysis by Mann Whitney revealed significantly difference (p<0,05) between normal group and all groups, negative control group and positive control group, and positive control group and treatment group I, but not significantly difference between negative control group and treatment group I, negative control group and treatment group II, positive control group and treatment group II, and between treatment groups. The study concluded that the effectivity of Artemisia vulgaris L. extract has not been proven as a hepatoprotector but further study is needed to draw a definite conclusion. Keywords: energy drink, niacin, Artemisia vulgaris L., hepatoprotector
Hubungan Jenjang Pendidikan terhadap Perilaku Menjaga Kesehatan Gigi dan Mulut Anak Tunagrahita di SLB Kota Sidoarjo Dianita Rahmah Julia; Ristya Widi Endah Yani; Roedy Budirahardjo
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.8661

Abstract

Intellectual disability is a child who suffers from intellectual ability below average and tends to have retardation in intelligence, physical, emotional, and social. They are not independent enough in keeping their own health especially oral hygiene, it can affect their oral health behavior. Education that is one of external factors influences health behavior. Education and knowledge influence each other so that people are expected to have high education in order to be knowledgeable especially in terms of maintaining health. The purpose of this study was to analyze the correlation between education level and oral health behavior of children suffering from intellectual disability. This research was an observational analytic research with cross sectional approach. The subjects of this study were a number of children of SDLB, SMPLB and SMALB in SLB Sidoarjo, with total sampling as many as 115 students. The subjects were asked to fill out a questionnaire of knowledge and attitude how to brush teeth and performed the action as well. The collected data were analyzed by using spearman correlation test. The result of this research showed that correlation coefficient for education level with knowledge, attitude and behavior was > 0,05, so there was no relation between those variables. Meanwhile, the result of correlation coefficient of education with action was < 0.05, so there was correlation between those two. The conclusion of this research is there is no correlation between the level of education and oral health behavior of intellectual disability children in SLB Sidoarjo. Keywords: Mental retarded, dental health behavior, education level
Sintesis dan Uji Aktivitas Antibakteri Senyawa N-fenil-4-klorobenzamida Elok Dea Orens Ubung Wisnu; Indah Purnama Sary; Dwi Koko Pratoko
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7569

Abstract

N-phenylbenzamide is benzamide derivatives, which is potential as an antibacterial agent. N-phenyl-4-chlorobenzamide is N-phenylbenzamide derivative that substitued by chloro to the para position and it was expected to enhance the antibacterial activity. N-phenyl-4-chlorobenzamide was synthesized by reacting 1,3-diphenyilthiourea and 4-chlorobenzoil chloride. This compound has been purified and provided 53% of product with crystal shape, white color, and melting point of 195-197 oC. The purification of this compound was confirmed by TLC and the structure was identified by 1H-NMR, 13C-NMR, and FTIR spectroscopy. This compound was tested for its activity against gram positive bacteria Staphylococcus aureus and gram negative bacteria Pseudomonas aeruginosa, evaluated by well diffusion method and the result showed no activity against both Staphylococcus aureus and Pseudomonas aeruginosa. Keywords: N-phenyl-4-chlorobenzamide, synthesis, antibacterial activity
Hubungan Mode Adaptif Konsep Diri Berbasis Teori Callista Roy dengan Kemampuan Interaksi Sosial Anak Tunagrahita di SLB-C TPA Kabupaten Jember Zuhrotul Rofiqoh; Nurfika Asmaningrum; Dodi Wijaya
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7777

Abstract

Self concept is one of adaptive modes based on Callista Roy’s theory which very important formental deficiency influence integrity of mental in practice to had a good social interaction. The kind ofthis research is descriptive analytic by using study cross sectional. Method of collecting samplesusing total sampling and total of samples got are 35 respondents. Data was analyzed by chi-squareand the result of statistical test shows point p=0.000. Ha is accepted if Ho is rejected in which Ho isrejected if the point is p ≤ α, 0,000 ≤ 0,05. The result of the statistic analysis is that there is significantcorrelation between adaptive modes: self concept based on Callista Roy’s theory and socialinteraction abilities to mental retardation children on SLB-C TPA at Jember Regency. OR (26.00),that means the respondents who had a positive self concept have 26.00 possibility to be had a goodsocial interaction abilities. The result of the research is positive self concept with good socialinteraction ability about 80%. Suggests for nursing in community to involve and increase their rolemodel as educator and care giver in attempt to share information by doing a counseling.Keywords: self concept, social interaction, mental retardation
Gambaran Histopatologi Organ Jantung Tikus Putih Jantan Galur Wistar (Rattus norvegicus) dalam Uji Toksisitas Akut Kombinasi Ekstrak Daun Jati Belanda (Guazuma ulmifolia Lmk.) dan Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Novia Hilma; Nuri Nuri; Endah Puspitasari; Indah Yulia Ningsih
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7574

Abstract

Jati belanda leaves (Guazuma ulmifolia Lmk.) and Roselle petals (Hibiscus sabdariffa L.) have been known for their activity as antihyperlipidemia with different mechanisms. Combination of these plants was expected to has a synergy effect in reducing cholesterol. However, the toxicity of jati belanda leaves and roselle petals extract combination must be investigated for knowing its safety. Based on the acute toxicity test, the LD50 value of jati belanda leaves and roselle petals extract combination was >5,000 mg/kg bw. It was classified as category 5 or unclassified. This research aimed to study about its effect in cardiac by cardiac histopathology examinations of the rats. The result showed that there was no cardiac histopathology changes of the rats at doses 5,000 mg/kg bw. Keywords: jati belanda leaves, roselle petals, acute toxicity, cardiac histopathology
Hubungan Tingkat Kebersihan Gigi dan Mulut dengan Karies pada Nelayan di Pesisir Pantai Watu Ulo Kabupaten Jember Yona Anindita; Kiswaluyo Kiswaluyo; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.8654

Abstract

Activity to cleanse and refresh the teeth and mouth is oral hygiene. Caries and periodontal disease will occure if not treating well, so they need to do the treatment to maintain the oral health. Fishermen usually sail in the afternoon and return in the next morning, sometimes they stay in the sea for a day. This situation causes the lack of attention of oral hygiene and increases the occurrence of dental caries. Researcher interests to analyze the relationship of oral hygiene levels with the caries of fishermen at Dusun Watu Ulo, Sumberejo Village, Jember District, East Java. This study performs oral hygiene examination using OHI-S index and caries examination using DMF-T index. This study aimed to determine the relationship between the level of oral hygiene with caries in fishermen at the coast of Watu Ulo Beach, Jember District.This observational analytic research was conducted by cross sectional approach. The method for sampling used Cluster Sampling. he average score of OHI-S fishermen at Watu Ulo coastal Jember District was 3.90 (bad category) and the average DMF-T index score was 3.10 (medium category). There was a weak relationship between oral hygiene with caries. Keywords: Oral hygiene, Caries, OHI-S, DMF-T, Fishermen.
Kadar Puncak (Cmax), Waktu Puncak (Tmax), Waktu Paruh (T½) dan Bersihan Teobromin pada Sukarelawan Sehat setelah Pemberian Dark Chocolate Bar Per Oral Nyoman Defriyana Suwandi; Cholis Abrori; Muhammad Hasan
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7620

Abstract

Dark chocolate contains two derivates of metilxantin, I.e. caffeine (1,3,7-trimetilxantin) and theobromine (3,7 dimetilxantin). Theobromine can be found in plasma. Theobromine concentration in plasma determined not only by drug dosage but also by pharmacokinetic parameters. This research aimed to determine pharmacokinetic parameters by using HPLC (High Performace Liquid Chromatography) method. This study used Quasi Experimental Design by using 16 plasma samples collected at the 0, 1.5, 3, 6, 10, 24 hours. The pharmacokinetic parameter calculations were obtained from the polynomial curve and linear curve of drug concentration in plasma by time. The maximum concentration (Cmax) theobromine on plasma after consumption of dark chocolate bar per oral was 4.173 mg/L. The maximum time (Tmax) was at the 2.501 hours. The half time (t½) theobromine was 4.880 hours. Theobromine clearance in plasma was 14.2 ml/kg/hour. The study has reported pharmacokinetic parameters of theobromine in plasma after eating dark chocolate bars orally. Keywords: Chocolate, half-time, maximum concentration, maximum time, theobromine
Efek Penambahan Vitamin C terhadap Aktivitas Klindamisin dalam Menghambat Pertumbuhan Streptococcus pneumoniae secara In Vitro Bagus Dwi Kurniawan; Dini Agustina; Erfan Efendi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.9744

Abstract

Pneumonia is one of the lower respiratory tract infection involving respiratory bronchioles and alveoli that mostly caused by Streptococcus pneumoniae.Clindamycin is one of the drug of choice for pneumoniae. This drugs inhibits the growth of S. pneumoniae by producing ROS (Reactive Oxygen Species). Recent study has shown that vitamin C could generate ROS leading to DNA-damage on bacteria. The aims of this study was to know the possible benefit effect of adding vitamin C towards clindamycin inhibition activity against the growth of S. pneumoniae in vitro. This research was conducted by using 7 groups which consist of negative control (aquades), positive control (clindamycin), and test group 1 until 5 that given the combination of clindamycin and vitamin C as follows 2,5 mg/ml; 5 mg/ml; 10 mg/ml; 20 mg/ml; and 40 mg/ml. The inhibition effect of growing S. pneumoniae shown by the inhibition zone diameter. The average of inhibition zone on negative control, positive control, and test group were 5; 24,12; 24,62; 26,08; 27,58; 28,74; and 29,76 mm. These result show a significant correlation based on Pearson test (the coefficient correlation’s result is +0,910). The logarithmic regression revealed the minimal concentration of vitamin C was 1,767 mg/ml. It can be concluded that vitamin C increased the activity of clindamycin by inhibiting the growth of S.pneumoniae in vitro. Keywords: Streptococcus pneumoniae, ROS, Clindamycin, Vitamin C
Hubungan antara Tingkat Pengetahuan Pasien dan Pengawas Menelan Obat (PMO) dengan Kepatuhan Pasien Tuberkulosis di Puskesmas Kabupaten Jember Antonius Nugraha Widhi Pratama; Amelya Prastica Rahayu Aliong; Nili Sufianti; Ema Rachmawati
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7570

Abstract

Tuberculosis (TB) is an infectious disease that mostly affects developing countries. In Indonesia, TB incidence increases every year due to patient inadherence to the standard DOTS therapy. The TB patients inadherence can be associated with poor knowledge among patients and treatment observers. This cross-sectional research aimed to explore the correlation between knowledge level of TB patients and their treatment observers and patient adherence. Purposive sampling technique was used to collect data from 65 respondents from their primary health centers in Jember Regency, East Java. Knowledge of the respondents was evaluated using a 16 items questionnaire and patient adherence was assesed using the translated version of morisky medication adherence scale-8 (MMAS-8) questionnaire. The Spearman Rho correlation test resulted in p value of 0,043 between patients knowledge and patients adherence. Statistically significant correlation was also found between the knowledge of treatment observers and TB patients adherence (p= 0,015). These results suggested the needs to improve knowledge about TB not only for TB patients, but also their treatment observers. Keywords: TB patient, treatment observer, knowledge, compliance
Pengaruh Pijat Bayi Terhadap Bounding Attachment di Ruang Dahlia RSD dr. Soebandi Jember Sri Wahyuni; Dini Kurniawati; Hanny Rasni
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7782

Abstract

Bounding attachment is very important for newborn to be adapted to the new environment. Mother’stouch can help babies adapt to environmental differences between inside the womb and outside thewomb. How to improve the bounding attachment is early breastfeeding initiation, rooming in,kangaroo mother care for premature, and baby massage. The purpose of this research is todetermine the impact of baby massage to bounding attachment. The method of research was quasiexperimental with design of research pretest-post test with control group. This research is in Dahliaroom in dr. Soebandi general Hospital, with samples as 40 respondent with 20 people forexperimental group and 20 people for control group. The research use standard operationalprocedure of baby massage and quality of bounding attachment questionnaire. Take the sample bypurposive sampling. The results of research is give difference in average pretest-post test on theexperimental group of -7,35 whereas on the control group of -2,55. Statistic test result obtained the pvalue 0.001, this mean on the alpha 5% can be expressed there is influence of baby massage forbounding attachment. There are several factors that influence to the bounding attachment that isemotional health of parent, family support, the proximity and match of the parents and baby. Theresult of this research are recommended as the nursing treatment and to the public especiallymother postpartum.Keywords : baby massage, bounding attachment

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