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Jurnal Anestesi Perioperatif
ISSN : 23377909     EISSN : 23388463     DOI : 10.15851/jap
Core Subject : Health, Education,
Jurnal Anestesi Perioperatif (JAP)/Perioperative Anesthesia Journal is to publish peer-reviewed original articles in clinical research relevant to anesthesia, critical care, case report, and others. This journal is published every 4 months with 9 articles (April, August, and December) by Department of Anesthesiology and Intensive Care Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung.
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Articles 484 Documents
Pengaruh Premedikasi Midazolam 0,04 mg/kgBB sebelum Anestesi Spinal terhadap Respons Tubuh saat Insersi Jarum Spinal dan Kepuasan Anna Christanti; Ezra Oktaliansah; Indriasari Indriasari
Jurnal Anestesi Perioperatif Vol 8, No 2 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n2.2035

Abstract

Conscious sedation pada pasien yang dilakukan tindakan anestesi spinal membuat pasien menjadi lebih nyaman, kooperatif selama penyuntikan, dan mengurangi respons tubuh saat insersi jarum spinal. Midazolam memiliki efek ansiolitik, sedatif-hipnotik, amnesia, melemaskan otot, dan mengurangi mual-muntah akibat pembedahan. Tujuan penelitian ini mengetahui pengaruh premedikasi midazolam 0,04 mg/kgBB yang diberikan 30 menit sebelum dilakukan anestesi spinal terhadap respons tubuh pasien saat insersi jarum spinal dan kepuasan pasien terhadap anestesi spinal. Penelitian dilakukan periode September–Desember 2019 di RSUP Dr. Hasan Sadikin Bandung. Penelitian bersifat prospektif eksperimental menggunakan uji klinis acak buta ganda terhadap 46 subjek yang dibagi acak ke dalam 2 kelompok, yaitu kelompok kontrol (kelompok K, n=23) dan kelompok premedikasi midazolam (kelompok M, n=23). Pasca- pemberian premedikasi midazolam dinilai respons tubuh pasien saat insersi jarum spinal menggunakan prick response score dan kepuasan pasien dengan numeric rating scale. Analisis statistik untuk respons penyuntikan dan kepuasan pasien diuji dengan uji chi-square. Hasil penelitian menunjukkan respons tubuh pasien saat insersi jarum spinal berkurang (p<0,01) dan kepuasan pasien meningkat (p<0,01) pada kelompok premedikasi midazolam. Simpulan, premedikasi midazolam 0,04 mg/kgBB yang diberikan 30 menit sebelum anestesi spinal menurunkan respons tubuh pasien saat insersi jarum spinal dan meningkatkan kepuasan pasien terhadap anestesi spinalThe Effect of Midazolam Premedication 0.04 mg/kgBW before Spinal Anesthesia to Body Response during Spinal Needle Insertion and Satisfaction Conscious sedation leads to a more comfortable spinal intervention for patients, making them more cooperative as well as  decreasing body response during spinal needle insertion. Midazolam has anxiolytic, hypnosis-sedative, amnesia, muscle relaxation effects and ability to reduce nausea and vomiting related to a surgery.  The aim of this study was to determine the effect of 0,04 mg/kgBW midazolam premedication administered 30 minutes before spinal anesthesia on body response during spinal needle insertion and patient satisfaction. The prospective experimental study with a randomized, double blinded clinical trial approach was conducted from September to December 2019 in Dr. Hasan Sadikin General Hospital Bandung. Forty-six subjects were randomly divided into 2 groups: a control group (group K, n=23), and a midazolam premedication group (group M, n=23). After premedication with midazolam, the patient`s body response during spinal needle insertion were evaluated using the prick response score and their satisfaction was assessed using the numeric rating scale. Statistical analysis used to analyze  body response during needle insertion and patient satisfaction was the Chi-Square test. Results howed that patient`s body response during spinal needle insertion were reduced (p<0.01) and patient satisfaction increased (p<0.01) in the midazolam premedication group. In conclusion, 0.04 mg/kgBW midazolam premedication administered 30 minutes before spinal anesthesia reduces patient body response during spinal needle insertion and increases patient satisfaction on spinal anesthesia.
Intervention in Undergoing Surgery with Undiagnosed Wolff-Parkinson-White Syndrome: Case Report Gezy Weita Giwangkancana; Astri Astuti; Dhany Budipratama; Aviryandi Wibawamukti; Fityan Aulia Rahman; Rani Septriana
Jurnal Anestesi Perioperatif Vol 8, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n3.2193

Abstract

Wolff-Parkinson-White (WPW) syndrome is a commonly undiagnosed cardiac rhythm anomaly in a previously healthy patient who may precipitate malignant arrhythmia under surgical stress. We report successful management of a reconstruction surgery patient who developed cardiac arrest under general anesthesia due to undiagnosed WPW syndrome and a malignant arrhythmia during subsequent emergency surgery. A male patient with no previous history of the co-existing disease, age 23 years old underwent 14 hours of leg reconstruction with a posterior back flap. At the end of the surgery, the patient developed malignant arrhythmia that worsens to pulseless ventricular tachycardia. High-quality resuscitation was conducted and resulted in the return of spontaneous circulation. The patient had to undergo emergency surgery the next day, and another episode of intraoperative malignant arrhythmia was treated with propafenone and diltiazem. The patient underwent ablation postoperatively and, on the 14th day, was discharged without any residual complications. In conclusion, WPW may appear asymptomatic in a healthy young patient. Good anesthesia management and monitoring, knowledge of selective antiarrhythmic drugs and high-quality resuscitation skills can provide an optimal outcome in an unpredicted intraoperative crisis.Laporan Kasus: Manajemen Pasien Sindrom Wolff-Parkinson-White (WPW) yang Menjalani Tindakan PembedahanSindrom Wolff-Parkinson-White (WPW) adalah kelainan irama jantung yang sering tidak terdiagnosis pada pasien usia muda dan sering tanpa gejala. Stres akibat pembedahan dapat memicu aritmia maligna pada kelainan ini. Kami melaporkan keberhasilan manajemen pada pasien bedah plastik rekonstruksi dalam anestesi umum yang mengalami henti jantung karena sindrom WPW yang tidak terdiagnosis sebelumnya dan terjadi aritmia maligna serupa pada operasi darurat berikutnya. Seorang laki-laki berusia 23 tahun tanpa riwayat penyakit penyerta sebelumnya, menjalani rekonstruksi kaki dengan flap posterior selama 14 jam. Pada akhir pembedahan, pasien mengalami aritimia maligna dan berkembang menjadi ventricular takikardia tanpa nadi. Tindakan resusitasi jantung paru berkualitas tinggi dilakukan dan sirkulasi spontan kembali muncul. Pasien harus menjalani operasi darurat keesokan harinya dan mengalami episode aritmia maligna ulangan intraoperatif yang telah berhasil diidentifikasi pada pemeriksaan pascaoperasi pertama sebagai sindrom Wolff-Parkinson-White. Aritmia maligna tersebut diatasi dengan pemberian propafenon dan diltiazem. Pasien menjalani tindakan ablasi pascaoperasi dan pulang pada hari keempat belas perawatan tanpa gejala sisa. Simpulan, sindrom WPW mungkin tampak asimtomatik pada pasien muda yang sehat. Manajemen anestesi yang baik, pengetahuan mengenai profil berbagai obat antiaritmia serta pelaksanaan tindakan resusitasi berkualitas tinggi dapat memberikan hasil keluaran yang optimal bila terjadi krisis intraoperatif yang tidak diperkirakan sebelumnya.
TATALAKSANA ICU PASIEN KRISIS MIASTENIA YANG DIPICU OLEH TUBERKULOSIS PARU DENGAN PENYULIT VAP Titik Setyawati; Reza Widianto Sujud; Indriasari Indriasari
Jurnal Anestesi Perioperatif Vol 8, No 2 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n2.2052

Abstract

Krisis miastenia adalah eksaserbasi akut miastenia gravis dengan kelemahan yang  melibatkan otot-otot pernapasan sehingga terjadi kegagalan napas akut dan memerlukan dukungan ventilasi mekanik. Krisis miastenia merupakan komplikasi miastenia gravis yang paling berbahaya dan mengancam jiwa bila tidak segera ditangani. Timbulnya krisis miastenia dapat dipicu oleh berbagai faktor, di antaranya infeksi dan penggunaan antibiotik aminoglikosid. Tata laksana Intensive Care Unit (ICU) pasien krisis miastenia meliputi tata laksana terhadap kegawatan respirasi, tata laksana terhadap miastenia gravis, dan tata laksana terhadap faktor peyulit. Intubasi endotrakeal dan dukungan ventilasi mekanis merupakan pilihan utama tata laksana kegawatan respirasi. Plasmaparesis adalah salah satu metode terapi yang terbukti efektif dan efisien selain pemberian agen anticholinesterase, terapi imunomodulator cepat, agen imunosupresif, dan timektomi. Terapi standar untuk menanggulangi tuberkulosis paru dengan obat antituberkulosis berdasar atas pedoman penatalaksanaan tuberkulosis serta terapi ventilator associated pneumonia (VAP) dengan pilihan antibiotik sesuai dengan hasil kultur bakteri. Dukungan nutrisi yang adekuat juga diperlukan untuk menunjang keberhasilan terapi. Dengan assessment dini dan terapi yang adekuat diharapkan dapat memperbaiki prognosis pasien krisis miastenia. Pada laporan kasus ini kami sajikan tata laksana ICU pasien krisis miastenia gravis yang dipicu oleh tuberkulosis paru dengan penyulit VAP yang dirawat di ICU RSHS Bandung pada bulan Oktober–November 2019. ICU Management of  Myasthenic Crisis in  Pulmonary Tuberculosis Patients with  Ventilator Associated Pneumonia ComplicationsMyasthenic crisis is an acute exacerbation of myasthenia gravis with a weakness that involves the respiratory muscles, leading to acute respiratory failure that requires mechanical ventilation support. Myasthenia crisis is the most dangerous and life-threatening complication of myasthenia gravis if not treated immediately. The emergence of myasthenic crisis can be triggered by various factors, including infection and aminoglycoside use. Intensive Care Unit (ICU) management of myasthenic crisis patients includes management of respiratory emergencies, management of myasthenia gravis, and management of complicating factors. Endotracheal intubation and mechanical ventilatory support are the main choices in the management of respiratory emergencies. Plasmaparesis is one of the proven and effective therapeutic methods in addition to anticholinesterase agent, rapid immunomodulatory therapy, immunosuppressive agent, and thymectomy. Standard therapy for treating pulmonary tuberculosis includes anti-tuberculosis drugs, as stated in tuberculosis management guidelines, and Ventilator Associated Pneumonia (VAP) therapy with antibiotic options according to bacterial culture results. Adequate nutritional support is also needed to support the success of therapy. With early assessment and adequate therapy, it is expected that the prognosis of myasthenic crisis patients will be improved. This case report presented  the management of myasthenia gravis crisis triggered by pulmonary tuberculosis with VAP complications in patients treated at the ICU of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from October to November 2019.
Perbandingan Efek Analgesia antara Fentanil dan Oksikodon Intravena untuk Pengelolaan Nyeri Pascabedah Laparotomi Kolesistektomi Thomas Thomas; Iwan Fuadi; Iwan Abdul Rachman
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2386

Abstract

Nyeri pascabedah harus diatasi dengan baik menggunakan analgetik yang memiliki efek analgesia adekuat dengan efek samping minimal. Penelitian ini bertujuan mengetahui perbedaan nyeri pascabedah laparotomi kolesistekomi yang dinilai dengan numeric rating score (NRS) antara pasien yang menggunakan continuous intravenous patient controlled analgesia (IV-PCA) fentanil dan oksikodon. Penelitian dilakukan pada periode Agustus–November 2020 di RSUP dr. Hasan Sadikin Bandung. Penelitian randomized control trial (RCT) dilakukan terhadap 32 subjek status fisik ASA I–II yang terbagi menjadi dua kelompok, yaitu kelompok yang mendapat continuous IV-PCA fentanil 0,5 µg/kgBB/jam dan kelompok dengan continuous IV-PCA oksikodon 30 µg/kgBB/jam. Nyeri pascabedah dinilai dengan NRS pada jam pertama, ke-6, ke-12, dan ke-24. Analisis statistik data numerik dengan Uji Mann-Whitney, data kategorik dengan uji chi-square dan alternatif Uji Fisher’s Exact. Nilai NRS pada kelompok oksikodon lebih rendah dibanding dengan fentanil pada jam pertama hingga jam ke-24 (p=0,001). Kebutuhan rescue analgetik pada jam pertama dan ke-6 juga lebih rendah pada kelompok oksikodon (p=0,012; p=0,022, berurutan). Penelitian dengan rasio fentanil:oksikodon 1:60 ini tidak menunjukkan perbedaan efek samping kejadian mual, muntah, pusing, sakit kepala, dan pruritus antara kedua kelompok. Pemberian analgesia oksikodon intravena pada pasien pascabedah laparotomi kolesistektomi lebih baik dibanding dengan fentanil intravena.Comparison of Analgesia Effect between Intravenous Fentanyl and Oxycodone for Postoperative Pain Management after Laparotomy CholecystectomyPostoperative pain must be addressed properly with adequate analgetic drugs and minimal side effects. This study aimed to determine the differences in postoperative cholecystecomy laparotomy pain assessed by NRS in patients receiving continuous PCA fentanyl or oxycodone. This was a randomized clinical trial on 32 subjects between August-November 2020 at dr. Hasan Sadikin Hospital Bandung. These subjects were divided into two groups: the group that received continuous intravenous infusion of PCA fentanyl 0.5 µg/kgBW/hour and the group with continuous intravenous infusion of PCA oxycodone 30 µg/kgBW/hr. Thepostoperative pain was assessed by NRS at the 1st, 6th, 12th, and 24th hours. Statistical analysis of numerical data was performed using the Mann-Whitney test while the categorical data were analyzed using Chi-Square test with alternative uji Fisher’s Exact test. Results showed that NRS was lower in the oxycodone group than in the fentanyl group at the first to 24 hours (p=0.001). The need for analgesic rescue at the first and sixth hours was also lower in the oxycodone group (p=0.012; p=0.022, respectively). The observation of opioid side effects on fentanyl:oxycodone with a ratio of 1:60 did not present any difference in the incidence of nausea, vomiting, dizziness, headache, and pruritus in both groups. The administration of intravenous oxycodone in postoperative cholecystectomy laparotomy patients gives better analgesia effect than intravenous fentanyl.
prediksi berat badan pasien pediatri : analisis akurasi mercy method di rsud dr soetomo surabaya Khildan Miftahul Firdaus; Arie Utariani
Jurnal Anestesi Perioperatif Vol 8, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n3.2098

Abstract

Resusitasi pediatri bergantung pada berat badan untuk menentukan ukuran alat resusitasi, dosis obat, jumlah cairan, hingga dosis defibrilasi yang dibutuhkan. Berat badan aktual pada kondisi kegawatan sering kali sulit diukur sehingga membutuhkan suatu metode prediksi. Mercy method merupakan salah satu modalitas prediksi berat badan berbasis panjang yang dapat digunakan. Tujuan, menganalisis akurasi Mercy method sebagai metode prediksi berat badan pasien pediatri. Metode, dalam penelitian analitik observasional ini dilakukan pengukuran berat badan, panjang lengan, dan lingkar lengan atas tengah pada pasien usia 2 bulan–16 tahun di IRNA Pediatri RSUD Dr. Soetomo periode Desember 2019 hingga Maret 2020. Panjang dan lingkar lengan atas tengah kemudian dikonversi menjadi berat badan prediksi menggunakan Mercy method, lalu dilakukan uji korelasi dengan berat badan aktual. Uji bias dan predictive performance dinilai menggunakan ME, MAPE, RMSE, dan toleransi berat badan hingga 10% dan 20%. Hasil, dari 375 pasien, didapatkan hasil bahwa Mercy method merupakan modalitas yang baik untuk memprediksi berat badan pediatri pada populasi ini (r2=.964; p,000). Hasil uji bias dan predictive performance juga menunjukkan hasil yang baik dengan ME yang rendah, MAPE <10%, RMSE mendekati nol, serta dapat memprediksi berat badan aktual dengan toleransi 20% hingga 97,4%. Simpulan, Mercy method merupakan metode yang akurat untuk memprediksi berat badan pasien pediatri di RSUD Dr. Soetomo Surabaya. Feasibility Analysis of the Mercy Method - Weight Estimation Pediatric PatientsMost pediatric resuscitations interventions are based on the patient's body weight to determine the resuscitation device’s size, drug dose, amount of fluid needed, and defibrillation joule. Measurement of actual body weight in the emergency setting is often impossible because it requires a weight estimation method. The Mercy method is one of the modalities of length-based weight estimation used in emergency departments. This study aimed to analyze Mercy method’s accuracy as a weight estimation method in pediatric patients at RSUD Dr. Soetomo Surabaya in December 2019–March 2020. This prospective,  observational analytic, single-center study, measured the actual body weight (ABW), humeral length (HL) and mid- arm circumference (MAC) of patients aged 2 months–16 years at the pediatric ward with consecutive sampling techniques. HL and MAC were converted to predictive body weight (PBW) based on Mercy method. Then, PBWs were regressed against ABWs. The predictive performance assessment used mean error (ME), mean absolute percentage error (MAPE), root mean square error (RMSE) and the predicted percentage was within 10% and 20% (Agreement 10% and 20%). Results from 375 pediatric patients showed that the Mercy method offered a good correlation between ABW and PBW (r2=.964, p.000); Mercy method also demonstrated good predictive performance results with low ME, MAPE <10% and RMSE close to zero. The Mercy method estimated weight within 20% of ABW for nearly all children (97.4%) in this study population. In conclusion, the Mercy method performed exceptionally well in this study population without modification, extending this weight estimation strategy.
Perbandingan Pemberian Morfin 15 mg Topikal dengan Bupivakain 0,25% Topikal pada Luka Operasi Modified Radical Mastectomy terhadap Waktu Bebas Nyeri dan Jumlah Kebutuhan Opioid Pascaoperasi Irwan Setiadi; M. Andy Prihartono; Erwin Pradian
Jurnal Anestesi Perioperatif Vol 8, No 2 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n2.2038

Abstract

Berbagai macam analgetik dapat diberikan untuk mengatasi nyeri pascaoperasi mastektomi, namun tidak ada yang ideal dalam menangani nyeri pascaoperasi. Teknik pemberian topikal adalah teknik terbaru untuk penanganan nyeri akut pascaoperasi modified radical mastectomy. Penelitian ini bertujuan membandingkan waktu bebas nyeri dan jumlah kebutuhan opioid pascaoperasi modified radical mastectomy. Penelitian menggunakan metode uji klinis acak terkontrol buta ganda melibatkan 38 pasien yang menjalani operasi modified radical mastectomy di RSUP Dr. Hasan Sadikin Bandung pada bulan November 2019–Februari 2020. Pasien dibagi menjadi dua kelompok, kelompok morfin 15 mg topikal (kelompok M, n=19) dan kelompok bupivakain 0,25% topikal (kelompok B, n=19). Analisis data menggunakan Uji  Mann Whitney karena distribusi data tidak normal berdasar hasil Uji Shapiro-Wilk. Hasil penelitian didapatkan bahwa waktu bebas nyeri lebih lama pada kelompok M (846,78±411,80 menit) dibanding dengan kelompok B (401,52±123,19 menit) dengan perbedaan yang signifikan (p<0,05). Total kebutuhan opioid kelompok M lebih sedikit, yaitu sebesar 1,15±0,60 gram dibanding dengan kelompok B sebesar 3,84±0,89 gram dengan perbedaan yang signifikan (p<0,05). Simpulan penelitian adalah pemberian morfin topikal memberikan waktu bebas nyeri lebih lama dan jumlah kebutuhan opioid pascaoperasi lebih sedikit dibanding dengan pemberian bupivakain topikal untuk nyeri pascaoperasi modified radical mastectomy.Comparison of Postoperative Pain Free Duration and Amount of Opioid Need between Topical 15 mg Morphine and 0.25% Bupivacaine Applications on Modified Radical Mastectomy Surgical Wound Various analgesic methods are implemented for reducing postoperative mastectomy pain, but none of them are ideal. Topical administration is the latest technic for managing postoperative pain in modified-radical mastectomy. This study aimed to compare pain free duration and the amount of opioid needed to manage pain after modified-radical mastectomy. This randomized double-blind clinical trial study with 38 patients underwent modified radical mastectomy in Dr. Hasan Sadikin General Hospital Bandung, Indonesia, was performed from November 2019 to February 2020. Subjects were divided into two groups, with one group received topical 15 mg morphine group (group M, n=19) and another received topical 0.25% bupivacaine group (group B, n=19). Data were analyzed using Mann Whitney test after they were proven to be non-normally distributed based on the results of the Shapiro-Wilk test. Results showed that the pain free duration was significantly longer in group M (846.78±411.80 minutes) when compared to group B (401.52±123.19 minutes) (p<0.05). The total dose needed for group M was 1,15±0,60 grams, which was significantly less than the dose needed in group B (384±0.89 grams) (p<0.05). In conclusion, topical morphine administration is associated with a longer pain free duration before the first onset of pain requiring opioid with less total amount of opioid needed when compared to bupivacaine for modified radical mastectomy postoperative pain.
Penggunaan Ventilatory Ratio dan Dead Space Fraction Sebagai Prediktor Mortalitas Pada Pasien COVID-19 dengan Acute Respiratory Distress Syndrome Muh Kemal Putra; Arie Utariani; Bambang Pujo Semedi; Christrijogo Soemartono Waloejo; Hardiono Hardiono
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2274

Abstract

Pada pasien COVID-19 dengan ARDS terjadi gangguan oksigenasi dan ventilasi. Menurut kriteria Berlin ARDS, oksigenasi diukur dengan PaO2/FiO2, namun tidak mengukur ventilasi alveolar yang diukur dengan dead space yang dapat terjadi akibat kondisi, seperti kerusakan endotel, mikrotrombus, dan penggunaan ventilator yang berlebih. Tujuan penelitian ini menganalisis penggunaan ventilatory ratio (VR) dan dead space fraction (Vd/Vt) sebagai prediktor mortalitas pasien COVID-19 ARDS. Penelitian ini adalah analitik kohort retrospektif. Data dikumpulkan dari rekam medik pasien COVID-19 yang dirawat di RIK RSUD Dr. Soetomo periode Juni–September 2020 dengan teknik total sampling terhadap subjek yang memenuhi kriteria inklusi dan tidak termasuk eksklusi. Data yang dikumpulkan adalah nilai VR dan Vd/Vt (diambil dari data laboratorium), kondisi klinis pasien dan pengaturan ventilator 24 jam pertama setelah terintubasi. Penelitian ini didapatkan 77 dari 80 subjek yang memenuhi kriteria. Nilai VR berhubungan dengan mortalitas secara signifikan dengan nilai p 0,001; cut off 1,84; sensitivitas 84,2%; spesifisitas 85%; RR 30,22; CI 95%: 7,31–124,89. Vd/Vt dan mortalitas menunjukkan hubungan yang signifikan terhadap mortalitas dengan nilai p 0.001. Uji analisis Spearman VR dengan Vd/Vt didapatkan hasil korelasi yang kuat dengan koefisien korelasi 0,704 dan p 0,001. Simpulan, nilai VR dan Vd/Vt dapat digunakan sebagai prediktor mortalitas pasien COVID-19 dengan ARDS dan keduanya mempunyai korelasi yang kuat. VR dapat menggantikan Vd/Vt.Use of Ventilatory Ratio and Alveolar Dead Space Fraction as Predictorz of Mortality in Covid-19 Patients with Acute Respiratory Distress SyndromeCOVID-19 with ARDS experience impaired oxygenation and ventilation. In Berlin ARDS criteria, oxygenation is measured by PaO2 /FiO2, but does not measure alveolar ventilation, which is measured through the dead space produced in this conditions, such as endothelial damage, microthrombus, and excessive use of entilator. The purpose of this study was to analyze the use of ventilatory ratio (VR) and dead space fraction (Vd/Vt) as predictors of mortality in patients with COVID-19 ARDS. This study was a retrospective cohort analytic study one medical records of COVID-19 patients treated in an inpatient unit of a referral hospital in Indonesia. The ethical clearance was obtained from the Health Research Ethics Committee of Dr. Soetomo Hospital, Indonesia. Data were collected through total sampling of medical records that met the inclusion and exclusion criteria. The VR and Vd/Vt scores were collected from the laboratory data, patient clinical condition, and ventilator setting 24 hours after intubation. Of all medical records screened, 77 out of 80 samples met the criteria. VR was significantly associated with mortality with a p value of 0.001 (cut-off point:1.84, sensitivity: 84.2%, specificity: 85%, RR: 30.22, and 95%, CI: 7.31–124.89). Similarly, Vd/Vt and mortality showed a significant relationship with mortality with a p value of 0.001 (cut-off: 0.25, sensitivity: 85%, specificity: 86%, RR: 34.71, 95% CI: 8.24–146.05). The Spearman analysis test between VR and Vd/Vt showed a strong correlation with a correlation coefficient of 0,704 and p 0,001. Thus, VR and Vd/Vt can be used as predictors of mortality in COVID-19 patients with ARDS and because both have a strong correlation. VR can also substitute Vd/Vt.
ANGKA KEJADIAN, LENGTH OF STAY, DAN MORTALITAS PASIEN ACUTE KIDNEY INJURY DI ICU RSUP DR. HASAN SADIKIN TAHUN 2018 Hidayat Hidayat; Erwin Pradian; Nurita Dian Kestriani
Jurnal Anestesi Perioperatif Vol 8, No 2 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n2.2054

Abstract

Angka kejadian acute kidney injury (AKI) di ICU tergolong tinggi dengan penyebab utama adalah sepsis dan menjadi salah satu faktor yang memengaruhi lama rawat dan mortalitas pasien di ICU. Angka kejadian, lama rawat, dan mortalitas AKI pada ICU di Indonesia belum diketahui. Tujuan penelitian ini mengetahui angka kejadian AKI, lama rawat dan mortalitas pasien AKI di ICU RSUP dr Hasan Sadikin pada tahun 2018. Penelitian ini merupakan penelitian deskriptif yang dilakukan pada 148 pasien yang dirawat di ICU RSUP dr. Hasan Sadikin Tahun 2018. Diagnosis AKI ditentukan melalui kriteria KDIGO dengan melihat peningkatan kreatinin serum dan penilaian urine output. Penelitian ini dilakukan mulai September 2019 sampai Februari 2020. Pada penelitian ini diperoleh sebanyak 61 pasien (41,2%) dengan diagnosis AKI, mayoritas pasien didiagnosis AKI tahap 3 yaitu sebanyak 32 pasien (53%). Sebanyak 14,8% pasien mendapatkan renal replacement therapy (RRT. Rerata lama rawat pada pasien AKI di ICU, yaitu 9,4±7,2 hari dan mortalitas sebesar 77%. Simpulan, angka kejadian AKI di ICU RSUP Dr. Hasan Sadikin Bandung tergolong tinggi, yaitu 41,2% serta mortalitas yang juga tinggi, yaitu 77%. Frequency, Length of Stay, And Mortality of Patients with Acute Kidney Injury at ICU Dr. Hasan Sadikin Hospital BandungIncidence of acute kidney injury (AKI) among patients treated in Intensive Care Units (ICU) is relatively high, mainly due to sepsis. The presence of AKI affects the patient’s length of stay (LOS) in the ICU as well as the mortality of ICU patients. In Indonesia, no data is available for the incidence of AKI in ICUs and the LOS and mortality rate of ICU patients with AKI. This study aimed to determine AKI incidence in ICU patients and the length of stay and mortality rate of ICU patients with AKI in Dr. Hasan Sadikin General Hospital in 2018. This was a descriptive study conducted on 148 patients treated at the ICU of Dr. Hasan Sadikin General Hospital 2018. The diagnosis of AKI was confirmed using the  Kidney Disease Improving Global Outcomes (KDIGO) criteria by observing the increase in creatinine serum and assessing the urine output. Data were collected during the period of September 2019 to February 2020 for analysis. Results showed that among 61 patients (41.2%) diagnosed with AKI, the majority were diagnosed with stage 3 AKI (n=32; 52.5%). A total of 14.8% of patients received RRT therapy. The mean LOS of AKI patients in ICU was 9.4±7.2 days and the mortality rate was 77%. Thus, the  incidence of AKI in the ICU of Dr. Hasan Sadikin General Hospital is relatively high (41.2%) with a high mortality rate (77%).
Perbandingan Penggunaan Masker Anestesi Berpewangi dengan Masker Anestesi Tidak Berpewangi terhadap Tingkat Kecemasan Anak pada Induksi Inhalasi Deni Nugraha; Dewi Yulianti Bisri; Radian Ahmad Halimi
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2387

Abstract

Induksi inhalasi dapat memberikan pengalaman emosi yang traumatis terhadap anak seperti perasaan terkekang atau tercekik selama bernapas melalui masker dan bau yang tajam dari gas anestesi. Salah satu pendekatan nonfarmakologis yang dapat dilakukan adalah menggunakan masker beraroma buah-buahan sebelum induksi. Modifikasi sederhana dengan mengoleskan lip balm dengan wangi buah pada permukaan dalam masker anestesi merupakan salah satu pendekatan yang efektif dan murah. Tujuan penelitian ini adalah mengetahui perbandingan pengaruh penggunaan masker anestesi berpewangi dibanding dengan masker anestesi tidak berpewangi terhadap tingkat kecemasan anak pada induksi inhalasi. Penelitian dilakukan menggunakan metode uji klinis acak terkontrol buta tunggal secara prospektif terhadap 38 anak berusia 4–12 tahun yang menjalani anestesi umum dengan status fisik american society of anesthesiologist (ASA) I–II di RSUP Dr. Hasan Sadikin Bandung. Subjek dibagi menjadi dua kelompok, yaitu kelompok yang mendapat masker berpewangi dan kelompok yang mendapat masker tidak berpewangi. Tingkat kecemasan anak di ruang persiapan dan kamar operasi dinilai menggunakan skala modified yale preoperative anxiety scale (MYPAS). Skala MYPAS adalah baku emas untuk evaluasi kecemasan anak yang terdiri atas 22 penilaian dalam 5 kategori dengan realibilitas dan validitas tinggi. Analisis statistik dengan Uji Mann-Whitney. Tingkat kecemasan anak pada kelompok masker berpewangi secara bermakna lebih rendah dibanding dengan kelompok masker tidak berpewangi (p=0,000), namun penilaian di ruang persiapan tidak menunjukkan hasil yang bermakna (p=0,07). Kesimpulan penelitian adalah penggunaan masker anestesi berpewangi pada induksi inhalasi menghasilkan tingkat kecemasan anak yang lebih rendah dibanding dengan penggunaan masker anestesi tidak berpewangi.Comparison of between the Use of Scented Anesthetic Mask and Unscented Anesthetic Mask on Anxiety Level in Children during Inhalation InductionInhalation induction may be a traumatic emotional experience in children as they may feel restricted or suffocated while breathing through the mask and inhaling the sharp smell of the anesthetic gas. A non-pharmacological approach that may be applied include the use of fruit scented masks before induction. This simple modification is done by smearing fruit scented lip balm on the anesthetic mask surface, which is an effective and inexpensive approach. This study aimed to compare the effects of scented anesthetic masks and non-scented masks on child anxiety level during inhalation induction. This was a single blind prospective randomized controlled trial on 38 children aged 4–12 years old underwent general anesthesia with a physical American Society of Anesthesiologist (ASA) status I–II in Dr. Hasan Sadikin General Hospital Bandung. Subjects were divided into two groups: scented mask group and unscented mask group. The anxiety levels in the preparation room and the operating room were measured using the Modified Yale Preoperative Anxiety Scale (MYPAS). MYPAS is the gold standard for evaluating anxiety in children, made up of 22 ratings in 5 categories with high reliability and validity. Statistical analysis was performed using the Mann-Whitney test. The anxiety level in the scented mask group were found to be significantly lower when compared to the unscented group (p=0.000) but the evaluation in the preparation room did not show statistically significant results (p=0.07). This study concludes that the use of scented anesthetic masks in inhaled induction results in lower anxiety levels in children.
Efektivitas dan Efisiensi Pencatatan efek Opioid pada Pasien Pascaoperasi di RSUP Dr. Sardjito, Indonesia Mahmud Mahmud; Sri Rahardjo; Rama Iqbal Mahendra; Titania Juwitasari; Siti Khamdiyah; Retno Koeswandari
Jurnal Anestesi Perioperatif Vol 8, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n3.2207

Abstract

Nyeri merupakan pengalaman sensoris dan emosional yang tidak menyenangkan terkait dengan kerusakan jaringan aktual atau potensial. Nyeri dapat terjadi saat preoperasi, durante, dan pascaoperasi. Pada umumnya, manajemen nyeri intra dan pascaoperasi menggunakan opioid. Penelitian ini bertujuan menilai efektivitas dan efisiensi pencatatan evaluasi penggunaan opioid intraoperatif dan pascaoperasi dan dilaksanakan pada Maret–Oktober 2019 di RSUP Dr. Sarjito Yogyakarta. Penelitian ini menggunakan desain kohort retrospektif untuk melihat efektivitas dan efisiensi pemberian opioid intraoperatif terhadap efek analgesia pascaoperasi dengan mengukur skala NRS, prevalensi kejadian efek samping opioid post-operative nausea and vomiting (PONV), recovery room length of stay (LOS), serta penggunaan obat analgetik pascaoperasi. Pencatatan rekam medis yang kurang lengkap sehingga tidak dapat menilai efektivitas penggunaan opioid intraoperative yang baik. Penggunaan opioid pascaoperasi memiliki hubungan yang bermakna dengan skor NRS 12 jam pascaoperasi dan kejadian komplikasi (p=0,025;p=0,028). Penggunaan opioid intraoperatif maupun pascaoperasi terhadap skor NRS, kejadian komplikasi, maupun lamanya waktu rawat di recovery room tidak terdapat hubungan yang bermakna. Simpulan, pencatatan evaluasi penggunaan opioid intraoperative dan pascaoperasi di rekam medis masih belum lengkap. Penggunaan opioid intraoperatif tidak bermakna dalam menurunkan skor NRS, menurunkan kejadian komplikasi pascaoperasi, memperpendek lama rawat di recovery room, namun apabila opioid dilanjutkan pemberian pascabedah menurunkan NRS, tetapi efek  samping opioid lebih tinggi. Effectiveness and Efficiency of Opioid Effects Recording in Postoperative Patients at Sardjito General Hospital, IndonesiaPain is “an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Postoperative pain is a pain felt by patients after a series of operations. In general, intraoperative and postoperative pains are treated with an opioid. This study aimed to determine the effectiveness and efficiency of recording evaluation of intraoperative and postoperative opioid use in patients. This study used a retrospective cohort design to identify the effectiveness and efficiency of intraoperative opioid administration on the postoperative analgesia effect by measuring the NRS scale, the prevalence of side effects of postoperative nausea and vomiting (PONV), Recovery Room length of stay (LOS), and the administration of postoperative analgesics. Due to incomplete medical records, it cannot assess the effectiveness of a good intraoperative opioid. Postoperative opioid use has a significant correlation with NRS score 12 hours postoperatively and the complication incidence (p=0.025, p=0.028). There was no significant relationship between either intraoperative or postoperative opioids to NRS score, adverse events, and length of stay in the Recovery Room. In conclusion, the recording of pain management in intraoperative and postoperative opioid use in the medical record is still incomplete. The intraoperative opioids use does not significantly reduce the NRS score, decrease the postoperative complications, and shorten the length of stay in the Recovery Room. If opioids are continued, postoperative administration significantly lower NRS; however, the side effects of opioids are higher.