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Dentika Dental Journal
Published by Universitas Sumatera Utara
ISSN : 1693671X     EISSN : 2615854X     DOI : -
Core Subject : Health,
Dentistry
d e n t i k a DENTAL JOURNAL is one of the journals managed by TALENTA Universitas Sumatera Utara which first published in 2015. This is an online scientific journal that publishes articles and scientific work from Researches, Case Reports and Literature Reviews in Dentistry and Dental Science. The scopes are varied from Dental Surgery, Dental Forensics, Oral Biology, Oral Medicine, Dental Public Health and Preventive Dentistry, Paediatric Dentistry, Dental Materials and Technology, Conservative Dentistry, Orthodontics, Periodontics, Prosthodontics, to Dental Radiology.
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Articles 390 Documents
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HUBUNGAN POLIMORFISME GEN VITAMIN D RESEPTOR DENGAN PERIODONTITIS KRONIS: POLYMORPHISM OF VITAMIN D RECEPTOR GENE IS ASSOCIATED WITH CHRONIC PERIODONTITIS Nurlindah Hamrun
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.304 KB) | DOI: 10.32734/dentika.v16i2.1826

Abstract

Chronic periodontitis is caused by enhanced resorption of the alveolar bone supporting the teeth and is associated with intraoral inflammation after infection with certain bacteria. Genetic polymorphisms in vitamin D receptor (VDR) gene are associated with bone homeostasis and immunological reaction. The aim of this study was to determine whether polymorphism in VDR gene exons is associated with the incidence of chronic periodontitis. A case-controll study was performed on a group of 162 subjects whose ages ranged from 25 to 60 years, were divided into two groups : 81 healthy individuals (control group) and 81 subjects with chronic periodontitis. The polymorphism in the VDR gene was analyzed by polymerase chain reaction, followed by TaqI restriction endonuclease digestion. The result showed that the polymorphism in the vitamin D receptor gene was found in chronic periodontitis with TT genotype (86.4%), Tt genotype (12.4%), and tt genotype (1.2%). This study also determines taqI polymorphism of the VDR gene is associated with the incidence of chronic periodontitis case (OR 12.57; CI: 1.6-99.8). In conclusion, polymorphism of the vitamin D receptor gene is associated with the incidence of chronic periodontitis (OR 12.57).
INCREASING OF GLYCOSAMINOGLYCAN AND HYDROXYPROLINE CONTENT IN RAT CARTILAGE MANDIBLES AFTER INSULIN LIKE GROWTH FACTOR–I INDUCTION: PENINGKATAN GLIKOSAMINOGLIKAN DAN HIDROKSIPROLIN PADA TULANG RAWAN MANDIBULA TIKUS SETELAH INDUKSI INSULIN LIKE GROWTH FACTOR-I I Gusti Aju Wahju Ardani
Dentika: Dental Journal Vol. 17 No. 2 (2012): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.874 KB) | DOI: 10.32734/dentika.v17i2.1829

Abstract

The cellular effects of Insulin Like Growth Factor-I (IGF-I) are mediated by binding to cell IGF-I receptors, which arefound mainly on cells of mesenchymal origin, such of fibroblast, chondrocytes, and osteoblast. The study suggests thatIGF-I may regulate chondrocytes proliferation, differentiation and extracellular matrix deposition. The purpose of thisstudy was to quantify a synthesis of hydroxyproline HYP and glycosaminoglycan (GAG) by primary chondrocyteculture with IGF-I at 0, 5, 25, and 50 ng/ml concentration. Chondrocyte proliferation was assessed with collagensynthesis and measured by using hydroxyproline (HYP) assay and glycosaminoglycan GAG synthesis was determinedwith dimethylmethylene blue dye binding assay for 10 days. Primary chondrocytes was cultured for 10 days with 0, 5, 25and 25 ng/ml IGF-I. The results showed that, IGF-I was a potent in increasing GAG synthesis and also effective inpromoting collagen HYP synthesis. At the 50 ng/ml concentration, IGF-I was upregultators of GAG synthesis, producing6 times more GAG than control. Collagen content was promoted by IGF-I at its lower concentration, with level 3 timeshigher than control. In conclusion, IGF-I at doses ranging from 5 to 50 ng/ml for ten days has proved the induction GAGand HYP synthesis in 10 days primary chondrocyte culture of secondary cartilage rat condyles.
OUTER MEMBRANE PROTEIN OF PORPHYROMONAS GINGIVALIS AS BASIC OF DIAGNOSTIC TOOL IN AGGRESSIVE PERIODONTITIS: PROTEIN MEMBRAN BAGIAN LUAR PORPHYROMONAS GINGIVALIS SEBAGAI ALAT DIAGNOSTIK PERIODONTITIS AGRESIF Desi Sandra Sari; Candra Bumi; Yuliana Mahdiyah DA
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.896 KB) | DOI: 10.32734/dentika.v16i2.1831

Abstract

Porphyromonas gingivalis is a gram-negative anaerobic bacteria and has been shown previously to be one of the major pathogens in aggressive periodontitis. Outer membrane protein is the major virulence factor of P. gingivalis and plays role in the host immune response impair againts P. gingivalis, which in turns, causing tissue destruction and bone resorption. This study was aimed to investigate the isolation and characteristic outer membrane protein of P. gingivalis. Protein of OMP P. gingivalis ATCC 33277 was isolated using sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) and than continued by hemaglutination test. The result showed that protein profil in SDSPAGE of OMP protein was 40 kDa molecular weight dan hemaglutination test was positive in titer of hemaglutination 1/8.In conclusion, outer membrane protein molecular mass of 40kDa produced by P. gingivalis is a key virulence factor involved in the co-aggregation activity of P. gingivalis
MANAGEMENT OF DENTAL ANTERIOR OPEN BITE WITH TONQUE THRUSTING IN GROWING PATIENT: PENATALAKSANAAN GIGITAN GIGI DEPAN TERBUKA KARENA KEBIASAAN MENDORONG LIDAH PADA PASIEN TUMBUH KEMBANG Ervina Sofyanti
Dentika: Dental Journal Vol. 17 No. 2 (2012): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.006 KB) | DOI: 10.32734/dentika.v17i2.1832

Abstract

Unfavorable growth pattern in vertical direction, heredity, digital habits, tonque function, and habitual mouth breathingare some abnormal functions that change the craniodentofacial morphology. This condition is also related with intensivebad habit that is not realized by the anterior open bite patient. Elimination of the ethiology factor and patient motivationinfluenced the success of anterior open bite correction. The aethiology of this anterior open bite can affect the treatmenttime, result, and stability of treatment. This case report describes orthodontic treatment systematically of a 17.5-year-oldboy with retrognatic profile who had thumb-sucking habit in the past, infantile swallowing, and tongue-thrusting. Thetype of anterior open bite was dental and malocclussion consisted of accentuated curve of spee at maxilla and reversedcurve of spee at mandible. The treatment started by correcting curve of spee along with instruction to keep oral muscleactivity in normal occlusal forces during orthodontic treatment. After the correction in vertical direction was achieved,four-premolar extractions were done. The result after 19-month-treatment showed overcorrection of overbite of +3.5 mm,overjet of +2 mm and tongue thrusting eliminated. In conclusion, the proper orthodontic treatment concurrently with badhabit management in growing patient will affect the treatment result and stability.
KEBIASAAN MENGISAP JARI PADA PASIEN TUMBUH KEMBANG: DIGIT SUCKING HABIT IN GROWING PATIENTS Ervina Sofyanti; Chen Kit Fong
Dentika: Dental Journal Vol. 17 No. 2 (2012): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.448 KB) | DOI: 10.32734/dentika.v17i2.1836

Abstract

Kebiasaan mengisap non-nutritif merupakan salah satu etiologi maloklusi open bite anterior dan crossbite posterior yangdapat muncul pada anak-anak yang sedang tumbuh kembang. Dalam tinjauan pustaka ini ditulis etiologi dan teori-teorikebiasaan mengisap jari sebagai pemahaman tentang kebiasaan ini secara khusus. Penelitian prevalensi pada daerah yangberbeda menunjukkan jumlah kasus yang berbeda pada masa yang tertentu dan penelitian longitudinal telah memberikangambaran perkembangan maloklusi secara bertahap pada usia tertentu. Selain pemeriksaan objektif, analisis fungsionalkebiasaan adalah penting sebagai prosedur diagnostik yang menjadi alat bantu dalam penentuan kebutuhan dan seleksiperawatan. Perawatan yang mampu membantu menghentikan kebiasaan termasuk pendekatan secara psikologis,pengunaan alat-alat non-dental dan piranti oral. Sebagai kesimpulan, perawatan yang menghambat kebiasaan mengisapjari mampu mencegah berkembangnya maloklusi dan kebiasaan ini harus dihentikan sebelum erupsi gigi permanen.
BAHAN BONDING DAN KAMFOROQUINON MAMPU MENINGKATKAN KEKERASAN RESIN KOMPOSIT SINAR-TAMPAK YANG MENGALAMI KEMAMPUAN MENGALIR: ABILITY OF BONDING AGENT AND CHAMPHOROGUINONE TO INCREASE VISIBLE LIGHT COMPOSITE RESIN HARDNESS IN FLOW READILY Ekiyantini Widowati; Dwi Warna Aju Fatmawati
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (141.792 KB) | DOI: 10.32734/dentika.v16i2.1838

Abstract

Bonding agent is a resin matrix that containing BIS-A-GMA without or with little filler. They bounded each other in enamel micromechanically in one side and chemically in the other side. Champhoroquinone is a photo-initiator of visible light composite resin (VLCR). It is light yellow fine powder form. Both of them help polymerization process of VLCR. The aim of the study was to know the ability of bonding agent and champhoroquinone to increase visible light composite resin hardness in flow readily. This study was laboratory experimental. The subjects were divided into 3 groups, they were champhoroquinone group (CPG), bonding group (BG), and control group (CG). Every group consisted of 24 specimens. VLCR paste was exposed under light of dental unit lamp for 2 minutes. After that, VLCR paste was added with bonding and champhoroquinone, and was mixed until homogen. Then, the mixed was taken into mould space (5 mm in diameter and 2 mm in thickness), was compressed and flatened, and was cured for 40 seconds. All samples were tested the hardness by Vikers Hardness Number (VHN). All data were analyzed by Kruskal Wallis Test and continued by Mann -Witney-U Test. The result showed that the mean of BG (56.96 VHN) was higher than CG (55.11 VHN) and CPG (51.19 VHN). The statistic test showed there was significant different between the group. In conclusion, the bonding agent can increase hardness of VLCR in flow readily and better than control and champhoroquinone group.
DIAGNOSA DAN PERAWATAN DISLOKASI KONDILUS MANDIBULA KE ANTERIOR: DIAGNOSIS AND ANTERIOR DISLOCATION MANAGEMENT OF MANDIBULAR CONDYLE Lucky Riawan; Alwin Kasim; Isnandar
Dentika: Dental Journal Vol. 17 No. 2 (2012): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.151 KB) | DOI: 10.32734/dentika.v17i2.1839

Abstract

Dislokasi kondilus mandibula ke anterior adalah translasi atau bergesernya kondilus mandibula keluar dari fossagleinodalis dan terkunci di antero-superior dari eminentia artikularis, menyebabkan terhalangnya gerakan menutup mulut,dimana umumnya ini terjadi karena hipermobilitas dari mandibula. Gangguan ini sering ditemukan dalam praktek doktergigi. Makalah ini membahas definisi dislokasi,etiologi, dan evaluasi klinis serta beberapa perawatanbaik secara bedahataupun non bedah. Dislokasi ini dapat terjadi pada satu sisi (unilateral) atau dua sisi (bilateral) dan dapat bersifat akut dankronis atau kronis yang bersifat rekuren. Penatalaksanaan dislokasi kondilus mandibula yang akut, umumnya dapatdilakukan dengan reposisi secara manual (non bedah), sedangkan pada yang kronis dan rekuren umumnya dilakukanintervensi bedah dalam penatalaksanaannya. Pemeriksaan fisik dan riwayat penyakit penting untuk mengevaluasi dengantepat semua kategori dislokasi, dan dislokasi harus direduksi sesegera mungkin sebelum terjadi spasme otot yang berat.Pengetahuan mengenai etiologi dari dislokasi ini penting dalam setiap kasus dan mungkin akan membutuhkan metodeperawatan yang berbeda. Sebagai kesimpulan, untuk menegakkan diagnosa dibutuhkan pemeriksaan secaralengkap. Penanganan dislokasi mandibula ini dapat dilakukan dengan teknik bedah ataupun non-bedah.
USE OF BUCCAL FAT PAD AS PEDICLED GRAFT IN CLEFT PALATE SURGERY: PENGGUNAAN BUCCAL FAT PAD SEBAGAI GRAFT PEDIKEL PADA BEDAH OBJEK TULANG PALATAL Olivia Avriyanti Hanafiah; Dhian Jun Frihatin Situmorang
Dentika: Dental Journal Vol. 17 No. 2 (2012): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.772 KB) | DOI: 10.32734/dentika.v17i2.1841

Abstract

Buccal fat pad (BFP) sebagai graft pedikel awalnya digunakan untuk merekonstruksi defek intra oral dengan ukuranmedium. Penggunaan graft pedikel untuk menutup defek tulang palatal dan mencegah atau memperbaiki fistula telahpopular akhir-akhir ini. Secara anatomis, BFP terdiri atas badan utama dan empat perluasan. Vaskularisasi BFPbersumber dari cabang arteri maksilaris, arteri temporalis superfisial dan fasial. Vaskularisasi yang berlimpah ke jaringanlunak memungkinkan terjadinya epitelisasi dengan cepat. Kemudahan pengambilan BFP, mobilisasi graft, pasokan darahyang sangat baik dan komplikasi yang minimal membuat graft pedikel BFP sebagai metode yang nyaman dan dapatdiandalkan pada penutupan celah langit-langit. Sebagai kesimpulan, flep pedikel BFP dapat dipertimbangkan sebagaiprosedur alternatif untuk memperluas pilihan terapi. Graft BFP memberikan keuntungan pada rekonstruksi celah langitlangit.
ANTIBACTERIAL EFFECT OF GLASS IONOMER AND ZINC OXIDE CHKM CEMENT AS ROOT CANAL FILLER TOWARD STREPTOCOCCUS VIRIDANS: EFEK ANTIBAKTERI SEMEN IONOMER KACA DAN ZINK OKSID CHKM SEBAGAI BAHAN PENGISI SALURAN AKAR TERHADAP STREPTOCOCCUS VIRIDANS Dwi Warna Aju Fatmawati; Ekiyantini Widowati
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.3 KB) | DOI: 10.32734/dentika.v16i2.1844

Abstract

Luting type glass ionomer cement (GIC) can be used as root canal filler. Because GIC has biocompatiblity and contained fluor, clinicians used zinc oxide ChKM (ZnOChKM) as root canal filler that contained parachorophenol, camper, and menthol. ChKM has a ability as wide spectrum antibacterial and low irritation. The Aim of study was to know antibacterial of luting type glass ionomer and zinc oxide ChKM as root canal filler toward Streptococcus viridans. This study was a laboratory experimental, contained of 7 samples of luting type GIC and 7 samples ZnOChKM cement. The characteristics were 2 mm of the thickness and 5 mm of diameter, non porous, homogen, and smooth. Each sample was taken in TSA medium that had been inoculated Streptococcus viridans. TSA medium was perforated by straw like the samples size. After samples were incubated for 1, 7, and 14 days, we measured inhibition zone around samples by caliper. All data was analyzed by T – test (α=0.05). The result showed that mean of ZnOChKM cement inhibition zone cement on the first day was 2.12 cm; seventh days was 2.46 cm; and 14th days was 2.86 cm. Mean of GIC inhibition zone on the first day was 0.46 cm; seventh days was 1.18 cm; and 14th days was 1.26 cm. ZnOChKM cement zone inhibition was large than GIC inhibition zone. T – test analysis showed there was significant different between ZnOChKM cement and luting type GIC in all observation time. In conclusion, ZnOChKM cement as a root canal filler was more effective than GIC to inhibit growth of Streptococcus viridans.
ACTIVITY TEST OF IMMUNOMODULATORY COMPONENT FROM NEEM LEAVES TO CANDIDA ALBICANS: UJI AKTIVITAS KOMPONEN IMUNOMODULATOR DARI NEEM TERHADAP CANDIDA ALBICANS I Dewa Ayu Ratna Dewanti; I Dewa Ayu Susilawat; Purwanto; Depi Praharani
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.333 KB) | DOI: 10.32734/dentika.v16i2.1845

Abstract

Empirically, societies have utilized neem plant to treat worm infection, scabies, malaria, candidal infection, and allergy. Several researches have indicated that consuming neem leaves could improve antibody production. Our previous research had demonstrated the existence of immunomodulatory component in neem leaves weighted 70 and 100 kDA. The aimed of study was to test the activity immunomodulatory components to Candida albicans. This research was an in vitro study with rats as experimental subject. The rats were divided into three treatment groups and one control group, which were labeled as KO (no treatment), KP1 (inoculated by C. albicans only), KP2 (inoculated by C. albicans and were given the 70 kDA immunomodulatory component), KP3 (inoculated by C. albicans and were given the 100 kDA immunomodulatory component). In day 21, preparations from rats’ tongue were done with immunohistochemistry staining and were analyzed for the activity of TNF-α macrophage phagocytosis and also for calculation of C. albicans colony from tongue swab. The result showed that there was no significant difference between the 70 and 100 kDA immunomodulatory components in increasing activity of TNF-α and macrophage phagocytosis and in decreasing the number of C. albicans colony. It was assumed that those components might actívate NF-κB and AP-1 that play role in protein transcription, which stimulated gene expression like TNF-α, which played role in phagocytosis. In conclusión, 70 dan 100 kDA immunomodulatory components increased the activity of TNF-α and macrophage phagocytosis and also decrease the number of C. albicans colony.

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