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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 30 Documents
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Search results for , issue "Vol 15 No 2 (2025): Medula" : 30 Documents clear
Review Article: Pharmacological Activities of Red Spinach (Amaranthus tricolor) Hasyimi, Meifia; Iqbal, Muhammad; Andrifianie, Femmy; Triyandi, Ramadhan
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1381

Abstract

  Red spinach (Amaranthus tricolor) is a leafy vegetable known for its distinctive red or purplish leaves. This plant is widely cultivated as its leaves are edible and packed with essential nutrients beneficial to the body. Red spinach is rich in antioxidants such as beta-carotene and vitamin C, along with vital minerals like iron, calcium, magnesium, phosphorus, and potassium, which support overall health. Regular consumption of red spinach is believed to improve blood circulation, boost immunity, prevent anemia, accelerate wound healing, and promote bone health due to its comprehensive nutritional content. This article aims to review the pharmacological activities of red spinach based on literature from credible sources such as Google Scholar, Garuda, Neliti, and Sinta, focusing on publications within the past five years. The review findings reveal that red spinach possesses various potential pharmacological properties. These include antioxidant activity, anemia treatment, reduction of liver enzymes such as SGOT and SGPT, improvement of liver function, and enhancement of metabolic processes. Additionally, red spinach is recognized for its benefits in maintaining facial skin health, suggesting its potential as a natural ingredient in skincare products. Therefore, red spinach is not only a nutritious vegetable but also holds promise as a natural herbal remedy with therapeutic potential for the future.
UJI DAYA HAMBAT EKSTRAK DAUN LIDAH MERTUA (Sansevieria trifasciata laurentii) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Saputra, Kurnia Hadi; Apriliana, Ety; Rodiani, Rodiani; Oktarlina, Rasmi Zakiah
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1579

Abstract

Infectious and communicable diseases remain one of the leading causes of mortality in Indonesia and worldwide. Several pathogenic bacteria can cause infections, one of which is Staphylococcus aureus. This bacterium can lead to a variety of conditions, including mastitis, dermatitis (skin inflammation), respiratory tract infections, impetigo, abscesses, toxic shock syndrome, and food poisoning. With the advent of antibiotics, an increasing number of bacterial strains have developed antibiotic resistance. The primary cause of this resistance is the widespread and irrational use of antibiotics, which allows some bacteria to survive and become resistant. The snake plant (Sansevieria trifasciata laurentii) contains compounds with antibacterial properties, such as tannins, saponins, and flavonoids. This study aimed to investigate the antibacterial activity of snake plant extract against Staphylococcus aureus. The research design used was a laboratory-based observational study. The antibacterial activity of the snake plant leaf extract was tested at concentrations of 20%, 40%, 60%, 80%, and 100% against Staphylococcus aureus using the dilution method to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The results showed that the snake plant extract exhibited antibacterial activity against Staphylococcus aureus at all tested concentrations (20% to 100%). The MIC was observed at a concentration of 20%, while the MBC was found at 40%. These findings confirm that the extract of Sansevieria trifasciata laurentii has inhibitory effects on the growth of Staphylococcus aureus.
Polycystic Kidney Disease Stadium Lanjut dengan Komplikasi Ekstrarenal pada Wanita 55 Tahun : Laporan Kasus Sihotang, Hillery; Sijabat, Hotmen
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1606

Abstract

Polycystic Kidney Disease (PKD) is an inherited kidney disorder characterized by the formation of multiple fluid-filled cysts in the kidneys, frequently involving other organs such as the liver. It is a progressive condition that can lead to end-stage renal disease (ESRD). This case report aims to explore the clinical course and management approach of a PKD patient with poor follow-up adherence since diagnosis. A 55-year-old female with a diagnosis of PKD since 2009 presented with abdominal enlargement, fatigue, and right upper quadrant discomfort. Despite a positive family history, the patient did not receive regular monitoring and relied on herbal remedies. Over 16 years, disease progression was marked by significant increases in serum urea and creatinine, development of multiple renal and hepatic cysts, and progression to chronic kidney disease (CKD) stage 4–5. The patient currently suffers from hepatic cyst complications and ESRD. This case highlights the accelerated progression of PKD in the absence of consistent clinical monitoring and early therapeutic intervention. It underscores the importance of early detection, regular renal function evaluation, patient and family education, and supportive care. Planning for renal replacement therapy and genetic screening of offspring are crucial to mitigate disease progression and improve outcomes in PKD patients.
PENGARUH EKSTRAK DAUN RANDU (Ceiba pentandra) TERHADAP PROSES PENYEMBUHAN LUKA SAYAT PADA MENCIT (Mus musculus L) Jezmy, Beby Kelidia; Oktarlina, Rasmi Zakiah; Sari, Ratna Dewi Puspita; Kurniawati, Evi
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1607

Abstract

Wound causes mechanical bleeding, inducing a response of the body to fix itself which undergoes a wound healing process through a few phases; hemostasis, inflammation, proliferation, and maturation or remodelling. Wound healing is a complex process due to biocellular and biochemistry activities occuring continously. One of the natural treatments is the administration of randu (Ceiba pentandra) leaf, a Spermatophyte which has been identified and used for its healing properties. This study was an experimental study with a post-test-only control group design, and datas were analyzed using a non-parametric Kruskal Wallis test. Treatments were given randu (Ceiba pentandra) leaf extract, grouped into 4: (K1): a negative control group, (P1): 40 ml of randu (Ceiba pentandra) leaf extract, (P2): 60 ml of randu (Ceiba pentandra) leaf extract, and (P3): 80 ml of randu (Ceiba pentandra) leaf extract. Through this study, randu (Ceiba pentandra) leaf extracts were rated based on the its wound healing rate and showed results of 80 ml, 60 ml, and 40 ml respectively. There is an effect of administration of randu (Ceiba pentandra) leaf extract on cut wound healing in mice (Mus musculus L) (p=0,037)  
The Management 52 Years Old Male With Hypercholesterolemia and Prehypertnsion Through Medical Approach Family in The Work Area of Puskesmas Tanjung Sari Natar Ahdalifa, Pinkan; Angraini, Dian Isti
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1608

Abstract

The prevalence of hypercholesterolemia in Indonesia increases with age. Hypercholesterolemia can cause cardiovascular and metabolic diseases. Riskesdas data shows abnormal cholesterol levels in the age of 45-55 years in Indonesia of 27.4%. Tekanan darah tinggi juga menjadi faktor risiko utama penyakit kardiovaskular. Risk factors for hypercholesterolemia and prehypertension are related to lifestyle so that they can be modified with appropriate management such as lifestyle interventions to prevent long-term complications and improve the quality of life of patients. Implementation of family doctor services based on evidence-based medicine in patients by identifying risk factors, clinical problems, and patient management based on a patient problem-solving framework with a patient-centered approach and a family approach. The analysis of this study is a case report. Primary data were obtained from anamnesis and physical examination. Secondary data were obtained from patient medical records at the Health Center. The assessment was carried out based on a holistic diagnosis from the beginning, process, and end of the study quantitatively and qualitatively. Patient Mr. M, 52 years old, came to the Tanjung Sari Natar Health Center with complaints of tingling in the feet, especially when the patient stood for more than 5 minutes since 3 days before. The patient was worried that his complaints could interfere with his daily activities. The patient is a casual laborer. Non-drug and drug interventions were carried out on the patient and his family with education related to the patient's illness in three home visits. The evaluation results obtained were that the patient's complaints decreased and the patient's and his family's knowledge regarding hypercholesterolemia increased. Holistic and comprehensive management of Mr. M's patient problems has been carried out by providing counseling to increase the knowledge of the patient and the patient's family.
Penatalaksanaan Perempuan Usia 48 Tahun Dengan Diabetes Melitus Tipe 2 Dan Prehipertensi Melalui Pendekatan Kedokteran Keluarga Di Wilayah Kerja Puskesmas Tanjung Sari Natar Miranda, Alyzah Nabila; Angraini, Dian Isti
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1610

Abstract

Diabetes Mellitus is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action or both. Diabetes Mellitus is one of the degenerative diseases with a high prevalence and is increasing every year. There is a possibility of an increase in the number of people with Diabetes Mellitus in the future, so comprehensive management must be carried out which is expected to prevent complications and improve the quality of life of patients. The purpose of this case report is to apply Evidence Based Medicine-based services to patients by identifying risk factors, clinical problems, and patient management based on a patient problem-solving framework with a patient-centered, family-focused, and community-oriented approach. This study is a case report. Primary data were obtained through anamnesis, physical examination and home visits to assess the physical environment. Assessment based on a holistic diagnosis from the beginning, process, and end of the study qualitatively and quantitatively. After the intervention, there was an increase in patient and family knowledge regarding the importance of health care checks, regular medication consumption, diet patterns and physical activity that are appropriate for people with Diabetes Mellitus. After holistic management with a family doctor approach, Mrs. N age 48 years with type 2 Diabetes Mellitus adjusted based on initial holistic diagnostics. The interventions carried out have increased patient and family knowledge about the importance of control to health workers, regular drug consumption, diet patterns and physical activity as indicated by improvements in the final holistic diagnostics.
PENATALAKSANAAN HOLISTIK PASIEN PADA PEREMPUAN USIA 25 TAHUN DENGAN ASMA PERSITEN RINGAN BERBASIS LAYANAN KEDOKTERAN KELUARGA DI WILAYAH KERJA PUSKESMAS KEDATON Sari, Zada Amalia Agatha; Susanto, Eko Budi
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1613

Abstract

Asthma is a heterogeneous disease, characterized by chronic inflammation of the airways characterized by a history of respiratory symptoms such as wheezing, shortness of breath, chest tightness, and coughing that vary in time and intensity, accompanied by variations in expiratory airflow obstruction. The purpose of this study is to apply a holistic and comprehensive family medicine approach in detecting internal and external risk factors and solving problems based on Evidence Based Medicine which is a family approach, patient-centered, community oriented. This research method uses a descriptive study of case reports. Primary data were obtained through autoanamnesis, physical examination, and home visits to patients. Secondary data were obtained from patient medical records at the Kedaton Health Center. The assessment was carried out based on a holistic diagnosis from the beginning, process, and end of the study quantitatively and qualitatively. The results obtained were that patient Ms. S, 25 years old, diagnosed with mild persistent asthma was managed comprehensively, namely given medication in the form of bronchodilators and inhalers and carried out interventions using poster media and showing asthma exercise videos. The evaluation showed that the results were in the form of improved patient complaints, increased understanding of the disease as evidenced by a comparison of pre- and post-test values, and increased family support. The conclusion obtained was that the application of a family doctor approach was needed for holistic and comprehensive management of patients with mild persistent asthma to detect internal and external risk factors in order to support the success of therapy and improve the patient's quality of life.
Penatalaksanaan Holistik Pada Pasien Laki-Laki Usia 54 Tahun dengan Gout Artritis dan Hipertensi Melalui Pendekatan Kedokteran Keluarga di Puskesmas Sumur Batu Attara Rafilia Adhata; Ernawati, Tutik
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1614

Abstract

Gout arthritis is a chronic progressive disease caused by the deposition of monosodium urate (MSU) crystals in the joints, kidneys and other connective tissues due to hyperuricemia. Based on the 2016 Bandar Lampung City health profile, hyperuricemia was included in the 10 most common diseases 141,857 cases. Hypertension is a condition when blood pressure is more than 140/90 mmHg. According to WHO, hypertension is a major problem that attacks 22% of the world's population. The purpose of this case report is to Identify internal risk factors, external risk factors, and clinical problems in patients. Implementing Evidence Based Medicine-based family doctor services for patients and patient management based on a framework for solving patient problems with a patient centered, family focused and community oriented approach. This study is a case report study. Primary data were obtained through history taking (autoanamnesis from the patient and alloanamnesis from the patient's family), physical examination and home visits. Secondary data were obtained from the patient's medical record. Assessment is based on a holistic diagnosis from the beginning, process, and end of the study qualitatively and quantitatively. Patient Mr.MY is 54 years old, has been diagnosed with gout arthritis and hypertension has concerns about his complaint is getting worse and cant be cured. The patient's hope is that the complaints disappear completely and do not recur. The patient's limited knowledge of the illness and an unfavorable lifestyle are factors that cause problems that occur in patients and their families. The diagnosis of gout arthritis and in this case is in accordance with several theories and critical studies from recent research. Management has been given in accordance with the management guidelines. There is good progress in patients starting from decreased clinical symptoms to changes in behavior after an intervention based on evidence-based medicine that is family-approach and patient-centered.
Penatalaksanaa Lansia Wanita Dengan Sindroma Metabolik Melalui Pendekatan Kedokteran Keluarga Di Wilayah Kerja Puskesmas Satelit Ratu Henggar Audrya Gharrieni; Dian Isti Angraini
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1616

Abstract

Metabolic syndrome is a collection of disorders that include insulin resistance, central obesity, dyslipidemia and high blood pressure. Definitions and criteria for diagnosing metabolic syndrome are constantly changing and are a topic of debate. In general, the prevalence of metabolic syndrome (SM) worldwide ranges from 20-25%, while in Indonesia it is 23.34%, with a higher prevalence in men (26.2%) than women (21.4%). Since hypertension and type 2 diabetes mellitus are chronic diseases and require long-term treatment, family physician services are needed to manage these diseases. The analysis in this study is a case report with primary data obtained from anamnesis and physical examination at the health center, and follow-up examinations during home visits to obtain environmental and social data. Secondary data were obtained from the patient's medical record at the Satellite Health Center. Assessment was carried out based on holistic diagnosis from the beginning, process, and end of the study quantitatively and qualitatively. In this case, diagnosis and treatment have been carried out according to theory and relevant journal references. After the intervention was given, there was an improvement in clinical symptoms and increased understanding of the patient and his family. The diagnosis and management of this patient was carried out holistically, patient centered, family approach, and community oriented. Based on a number of recent theories and studies, there is an increase in knowledge among the patient's family.
HOLISTIC MANAGEMENT OF A 48 YEAR OLD MAN WITH MATURE CATARACT AND GRADE II OBESE THROUGH A FAMILY MEDICINE APPROACH IN THE WORK AREA OF RAJABASA INDAH COMMUNITY HEALTH CENTER Farida, Lulu; Ernawati, Tutik
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1617

Abstract

Senile cataracts and obesity are two prevalent health conditions frequently observed among the adult and elderly population. Senile cataracts are characterized by lens clouding, leading to visual impairment, while obesity involves excessive fat accumulation, which can exacerbate ocular health through mechanisms of oxidative stress and systemic inflammation. The aim of this study was to apply a holistic and comprehensive family medicine approach to identify both internal and external risk factors and manage these issues based on Evidence-Based Medicine, incorporating family-approached, patient-centered, and community-oriented care. This research was conducted as a case report, with primary data gathered through anamnesis, physical examination, and home visits, and secondary data collected from the patient’s medical records. The case involved a 48-year-old male, Mr. D, who presented with progressively worsening blurred vision in his right eye over the past five months, originating two years prior. The patient reported overeating habits without regular physical activity. Physical examination revealed stable vital signs and a BMI of 36.3 kg/m² (obesity grade II). Local eye exam findings showed a right eye visual acuity of 1/300 with lens opacity and a negative shadow test. Both the patient and his family expressed concern due to their limited understanding of his condition. The diagnosis and management were carried out holistically—emphasizing patient-centered care, family involvement, and community support—based on current theories and research. Post-intervention, there was a notable improvement in the patient’s and family’s knowledge and behavior, contributing to better quality of life and overall health maintenance.

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