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All Journal Medula Science and Technology Indonesia Jurnal Ilmu Kedokteran dan Kesehatan Community Development Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Journal of Language and Health Jurnal Pengabdian Fakultas Pertanian Universitas Lampung
Ety Apriliana
Bagian Mikrobiologi, Fakultas Kedokteran, Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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HUBUNGAN LAMA DEMAM DENGAN MANIFESTASI PERDARAHAN DAN KEBOCORAN PLASMA PASIEN ANAK PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK BANDAR LAMPUNG Alvinasyrah, Alvinasyrah; Apriliana, Ety; Kurniawaty, Evi
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 3 (2024): Volume 11 Nomor 3
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i3.13481

Abstract

Abstrak: Hubungan Lama Demam dengan Manifestasi Perdarahan dan Kebocoran Plasma Pasien Anak Penderita Infeksi Dengue di RSUD Dr. H. Abdul Moeloek Bandar Lampung. Infeksi dengue merupakan penyakit yang disebabkan oleh virus dengue dengan vektor pembawa Aedes aegypti L. dan Aedes albopictus. Infeksi dengue ditandai dengan demam tinggi, manifestasi perdarahan, dan kebocoran plasma. Manifestasi perdarahan terdiri dari petekie, epistaksis, perdarahan gusi dan gastrointestinal; kebocoran plasma terdiri dari peningkatan hematokrit ≥20%, efusi pleura, asites, dan hipoalbuminemia. Tujuan penelitian ini, untuk mengetahui hubungan lama demam dengan manifestasi perdarahan dan kebocoran plasma pasien anak penderita infeksi dengue di RSUD Dr. H. Abdul Moeloek Bandar Lampung. Jenis penelitian ini adalah penelitian observasional dengan desain penelitian potong lintang. Data diambil dari catatan rekam medik pasien infeksi dengue (≤18 tahun) selama tahun 2018-2019 di RSUD Dr. H. Abdul Moeloek Bandar Lampung. Analisis data dilakukan menggunakan uji Chi square dan Fisher’s exact. Hasil penelitian menunjukkan 50,5% berusia 6-12 tahun, 50,5% pada perempuan, 48,5% terdiagnosis DBD II, 27,3% demam hari 4 dan 6. 58,6% mengalami petekie dan 47,5% mengalami peningkatan hematokrit. Hasil uji Fisher’s exact dan Chi square menunjukkan nilai p= 0,232 pada manifestasi perdarahan dan nilai p= 0,139 pada kebocoran plasma. Kesimpulannya tidak terdapat hubungan antara lama demam dengan manifestasi perdarahan dan kebocoran plasma pasien anak penderita infeksi dengue di RSUD Dr. H. Abdul Moeloek Bandar Lampung.  
Diare adalah kondisi yang ditand Ecoli Penyabab Diare Akut : Ecoli Penyabab Diare Akut: Patogenesis, Diagnosis dan Tatalaksana Shinta Dewi, Brigitta; Soleha, Tri Umiana; Septiani, Linda; Apriliana, Ety
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.903

Abstract

The presence of Escherichia coli bacteria or what is often called E.coli is an indicator of contaminated food and water which shows that there is contamination in human feces. 16 Research results show that consuming food contaminated with Escherichia coli bacteria can cause symptoms of diarrhea, pain, fever, and vomiting6. Escherichia coli bacteria can be transmitted through contact with infected food handlers when processing food16. Escherichia coli can be transmitted from feces through contact with human fingers, flies, soil and water that comes into direct contact with food and eating utensils19. Diarrhea in Indonesia is an endemic disease and a potential disease that is associated with a significant mortality rate. In that year, there were 21 extraordinary events (KLB) which spread across 12 provinces and 17 districts/cities. 12. An increase in diarrhea occurred in 2018 with the number of cases reaching 4,504,524 people. In 2019, diarrhea cases decreased slightly to 4,485,513 people. The national incidence rate of diarrhea is 270 per 1,000 population12. In 2020, diarrhea in Bandar Lampung City reached 16,989, in 2021 there was an increase with the number of cases 22,371 (Central Statistics Agency for Bandar Lampung City, 2023) 4. Knowledge and updates regarding E. Coli as a cause of diarrhea are important for medical personnel.
Faktor-Faktor yang Mempengaruhi Keparahan Derajat Infeksi Dengue pada Pasien Anak Rahel, Clara Arta Uli; Apriliana, Ety; Septiani, Linda; Soleha, Tri Umiana
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.954

Abstract

Dengue infection is an infectious disease transmitted by mosquitoes, especially Aedes species which have been infected to humans. Dengue virus (DENV) consists of four serotypes, namely DEN-1, DEN-2, DEN-3, and DEN-4. Dengue virus infection in humans, especially in pediatric patients, can cause different symptoms from one patient to another. To make it easier to classify the patient's condition, WHO has classified the clinical severity of dengue infection, namely dengue fever, dengue hemorrhagic fever which consists of four levels, and dengue shock syndrome. The varying progression of dengue infection is the basis for knowing the factors that can influence the severity of the degree of dengue infection in terms of the patient's characteristics, clinical symptoms and laboratory results.
Retinopati Diabetik yang Mengancam Penglihatan Oktaryona Trisera; Himayani, Rani; Apriliana, Ety; Yusran, M
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1070

Abstract

Diabetic retinopathy is a progressive microangiopathy characterized by retinal vascular damage and blockage. The global prevalence of diabetic retinopathy is 34.6%. Clinical manifestations in patients with diabetic retinopathy include aneurysms, vein dilation, vitreous hemorrhage, and hard exudates which can affect visual acuity. Progression of diabetic retinopathy can potentially threaten vision and even blindness even though initially there are no severe clinical manifestations. Visual-threatening diabetic retinopathy is classified into severe NPDR, PDR, and all DR with diabetic macular edema. The global prevalence of VTDR is 7.26% and according to research by Sasongko et al (2017) states that 1 in 4 DM patients has a vision-threatening DR condition (VTDR). The best management of DR is prevention in the form of early screening, education, and counseling, especially in DM patients. For patients who have been diagnosed with DR, follow-up treatment, laser, injection, or even surgery, depending on the severity.
Novel Micrococcus unila to Produce Glucosamine by Solid-state Fermentation of Shrimp Shell Waste Setiawan, Wawan Abdullah; Setiawan, Andi; Salsabila, Nafila Khansa; Widyastuti, Widyastuti; Laila, Aspita; Juliasih, Ni Luh Gede Ratna; Irawan, Bambang; Ahmadi, Peni; Apriliana, Ety; Arai, Masayoshi; Hendri, John
Science and Technology Indonesia Vol. 9 No. 4 (2024): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.4.779-789

Abstract

This study aimed to assess glucosamine production through enzymatic activity, utilizing actinomycetes sourced from shrimp shell waste (SSW) in a solid-state fermentation (SSF) process. A total of 16 actinomycetes underwent chitinase activity screening, and the strain exhibiting the highest chitinolytic index was chosen for subsequent morphological and phylogenetic analyses. High Performance Liquid Chromatography (HPLC) was employed to analyze glucosamine produced from the bioconversion of SSW via SSF. Optimal conditions for glucosamine production were determined by varying time, pH, and temperature. Isolate 18D36-A2 showed the highest chitinolytic index of 1.02 in the 32-mm clean zone. Phylogenetic analysis revealed 97% similarity to the genus Micrococcus, identifying it as a novel Micrococcus unila strain 18D36-A2 and deposited in GenBank. This isolate effectively converted shrimp shells. The findings showcase the bioconversion of SSW to glucosamine through SSF using the Micrococcus unila 18D36-A2. Furthermore, this study establishes a foundation for future research on environmentally friendly and sustainable designs for glucosamine production.
Perbedaan Usia, Gejala Klinis, Hasil Leukosit Total dan Hemoglobin Berdasarkan Hasil Pemeriksaan Titer Widal Pasien Demam Tifoid Frauprades, Kaltihennah Oktavia; Apriliana, Ety; Ismunandar, Helmi; Soleha, Tri Umiana
Journal of Language and Health Vol 5 No 2 (2024): Journal of Language and Health
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jlh.v5i2.4060

Abstract

Indonesia merupakan salah satu negara endemis demam tifoid. Salah satu pemeriksaan yang umum dilakukan untuk menunjang penegakkan diagnosis demam tifoid yaitu menggunakan uji widal namun banyak faktor yang memengaruhi titer widal pasien demam tifoid. Penelitian ini menggunakan pendekatan cross sectional dengan teknik pengambilan sampel menggunakan total sampling dan data yang digunakan berasal dari rekam medis pasien demam tifoid di RSUD dr. A. Dadi Tjokrodipo tahun 2019-2020. Hasil penelitian menunjukkan tidak adanya perbedaan yang bermakna antara usia (p = 0,075), gejala klinis (p = 0,813), hasil leukosit total (p = 0,510), dan hasil hemoglobin (p = 0,742) berdasarkan titer widal H. Penelitian ini juga tidak menunjukkan perbedaan bermakna antara gejala klinis (p = 0,495), hasil leukosit total (p = 0,360), dan hasil hemoglobin (p = 0,893) berdasarkan titer widal O. Dari berbagai variabel yang dianalisis, hanya usia pada titer widal O yang menunjukkan perbedaan signifikan (p = 0,009). Terdapat perbedaan yang bermakna antara usia berdasarkan titer widal O.
Training on Early Detection of Chronic Energy Deficiency in Pregnancy Angraini, Dian Isti; Apriliana, Ety; Zuraida, Reni; Saftarina, Fitria
Community Development Journal Vol 8 No 1 (2024): Community Development Journal
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/cdj.v8i1.5728

Abstract

Chronic Energy Deficiency in pregnancy is a condition where pregnant women suffer from a lack of food that lasts for a long time. Pregnant women with chronic energy deficiency have poor eating behavior, which is influenced by knowledge, perception, beliefs and health education. Health education provided by health workers can increase knowledge and change eating behavior and can be done better if assisted by an expert system. The aim of this activity is to train health workers (doctors, midwives, nutritionists) to carry out early detection of chronic energy deficiency in pregnancy using an expert system, increasing knowledge, attitudes and eating behavior of pregnant women. The method that will be carried out is training using the web-based expert system modelangraini.com for health workers, health education for pregnant women, and increasing knowledge and changing eating behavior of pregnant women. This activity was carried out for 1 day and took place in Faculty of Medicine, University of Lampung on Saturday 30 September 2023 with 45 family doctors, midwives and nutritionists in Bandar Lampung City participating. The results of the evaluation of the implementation of the service showed that there was an increase in participants' understanding by 91.1% to good understanding, 8.9% of participants had a fairly good understanding, and no participants had a poor understanding of the causes, risk factors, impacts, prevention methods, and early detection of chronic energy deficiency in pregnancy with techniques that are fast, easy and can help health workers in providing education and interventions on the eating behavior of pregnant women. This training activity can improve the skills of health workers in an effort to increase knowledge, attitudes and eating behavior of pregnant women so that they can prevent, overcome and help reduce the prevalence of chronic energy deficiency in pregnant women and prevent stunting in toddlers. Keywords: early detection, chronic energy deficiency, training, health workers
Sepsis neonatal atau biasa dikenal dengan sepsis neonatorum merupakan infeksi yang melibatkan seluruh aliran darah dan semua organ-organ pada bayi baru lahir yang berusia kurang dari 28 hari. Penyakit ini masih menjadi penyebab utama morbiditas dan mort Sabila, Ghina; Apriliana, Ety; Islamy, Suryadi; Sari, Ratna Dewi Puspita
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1258

Abstract

Neonatal sepsis is a systemic infection that involves the entire bloodstream and organs of newborns, making it one of the leading causes of neonatal morbidity and mortality, particularly in low- and middle-income countries. Neonatal sepsis is classified into early-onset sepsis (EOS) and late-onset sepsis (LOS), with varying etiologies involving gram-positive bacteria, gram-negative bacteria, and fungi. This article aims to provide a comprehensive review of the etiology, risk factors, diagnosis, and management of neonatal sepsis using an evidence-based approach. This article is based on an analysis of current literature relevant to the epidemiology, pathogenesis, and treatment of neonatal sepsis. EOS is primarily caused by vertical transmission of infection during delivery, with Group B Streptococcus (GBS) as the leading cause, while LOS is often associated with nosocomial infections caused by Staphylococcus epidermidis. Risk factors include prematurity, low birth weight, invasive procedures, and poor infection control. Management involves the administration of broad-spectrum empirical antibiotics within one hour of suspected sepsis, tailored to culture results. A holistic approach, including NICU care, family education, and optimization of infection prevention, has been shown to effectively reduce morbidity and mortality. Neonatal sepsis remains a significant challenge in perinatology, necessitating comprehensive management with an evidence-based approach encompassing timely antibiotic therapy, nosocomial infection control, and family education to improve neonatal outcomes. Preventive efforts, such as enhancing perinatal hygiene and neonatal care, must be optimized to reduce the incidence of neonatal sepsis.
Pengaruh Waktu Inkubasi Terhadap Daya Hambat Ekstrak Daun Binahong Pada Cutibacterium Acnes Alvista, Valentina Nancy; Sibero, Hendra Tarigan; Aditya, Muhammad; Apriliana, Ety
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1272

Abstract

Acne (Acne vulgaris) is a common skin disorder often caused by the bacterium Cutibacterium acnes. Bacterial resistance to antibiotics used in acne treatment has become a significant concern. This study evaluated the effect of incubation time on the diameter of the inhibition zone produced by binahong (Anredera cordifolia) leaf extract in inhibiting the growth of C. acnes. The well diffusion method was employed using extract concentrations of 25%, 50%, 75%, and 100%. Data analysis was conducted using a paired t-test. The results showed a significant difference (p < 0.001) in the inhibition zones formed based on variations in incubation time. The findings indicated that longer incubation times resulted in larger inhibition zones. Binahong leaf extract was found to be effective in inhibiting the growth of C. acnes, particularly at higher concentrations and with longer incubation durations. These results demonstrate the potential of binahong leaf extract as an effective acne treatment to address antibiotic resistance.
Faktor-faktor yang Berhubungan dengan Keberadaan Escherichia Coli (E. Coli) pada Makanan dan Minuman Sihaloho, San Maulina; Tugiyono, Tugiyono; Suharmanto, Suharmanto; Apriliana, Ety; Pramesona, Bayu Anggileo
Journal of Language and Health Vol 6 No 1 (2025): Journal of Language and Health
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jlh.v6i1.5736

Abstract

Bakteri Escherichia coli (E. coli) merupakan salah satu indikator untuk menilai penerapan sanitasi pangan. Infeksi bakteri E. coli meningkat setiap tahunnya. Tujuan literature review ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan keberadaan E. coli pada makanan dan minuman. Literature review ini dilakukan dengan menelusuri artikel menggunakan search engine seperti Google Scholar dan PubMed. Artikel yang digunakan adalah artikel 10 tahun terakhir dari tahun 2015-2025. Kata kunci yang digunakan adalah keberadaan bakteri E. coli, makanan dan minuman dan penjamah makanan. Peneliti mendapatkan 300 artikel, dan 8 artikel yang memenuhi syarat untuk dilakukan analisis. Peneliti melakukan analisis hasil dan melakukan interpretasi hasil penelitian. Hasil penelitian mendapatkan bahwa adanya bakteri E.coli dalam makanan dapat disebabkan banyak faktor antara lain, air bersih yang mengandung E.coli, penjamah makanan yang kurang higienis, alat yang digunakan, bahan makanan, atau cara pengolahan makanan. Faktor yang berhubungan dengan keberadaan bakteri E. coli meliputi jarak sumber pencemar, kondisi dan konstruksi sumur yang tidak memenuhi syarat, serta higiene penjamah makanan. Ketidakberhasilan dalam menjaga kebersihan dapat menyebabkan kontaminasi, sehingga E. coli menjadi indikator adanya pencemaran, terutama dalam air minum dan makanan.
Co-Authors Agustin, Nur Aini Ahmadi, Peni Alvinasyrah, Alvinasyrah Alvista, Valentina Nancy Andi Setiawan Arai, Masayoshi Aspita Laila Bayu Anggileo Pramesona Dian Isti Angraini Dian Septinova Dwi Indria Anggraini Dyah Wulan Sumekar Rengganis Wardani Fitria Saftarina Frauprades, Kaltihennah Oktavia Giska Tri Putri Helmi Ismunandar Hendra Tarigan Sibero Hermawan, Alan Ildha Rosendy Kurnianda Intanri Kurniati Islamy, Suryadi John Hendri Juliasih, Ni Luh Gede Ratna Kurniawaty, Evi Legowo, Ahmad Bambang Madi Hartono Muhammad Aditya, Muhammad Nugraha, Ega Oktaryona Trisera Rahel, Clara Arta Uli Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Reni Zuraida Rito, Hardiansyah Faisal Rodiani, Rodiani Sabila, Ghina Salsabila, Nafila Khansa Saputra, Kurnia Hadi Selawati, Diyah Septiani, Linda Shinta Dewi, Brigitta Sihaloho, San Maulina Silitonga, Yona Arisena Magdalena Sinaga, Herman Fransiskus Suharmanto Tengku Riza Zarzani N Tri Umiana Soleha Tugiyono Tugiyono WAWAN ABDULLAH SETIAWAN, WAWAN ABDULLAH Widyastuti Widyastuti Yusran, M