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Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Published by Universitas Ahmad Dahlan
ISSN : 14127946     EISSN : 25035223     DOI : 10.12928
Core Subject : Health, Science,
Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology
Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal Media Farmasi selected by editors and reviewed by the reviewer. Articles published in Media Farmasi must not be published in other journals or have been previously published. Media Farmasi publishes a review article, original article, as well as short communication in all scopes of Pharmaceutical Science.
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Articles 4 Documents
 1 
Search results for , issue "Vol. 21 No. 2: September 2024" : 4 Documents clear
Optimization of Glycerin and Sorbitol in Hand Sanitizer Cream with Centella asiatica (L.) Extract Novela, Yuven; Yuliani, Sri Hartati
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 2: September 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i2.25629

Abstract

The use of alcohol-based hand sanitizers can cause dry skin. Centella asiatica (L.) extract can be used as an alternative to alcohol because it contains triterpenoids, especially asiatic acid, potentially an antibacterial and inhibitor of the SARS-CoV-2 virus. Cream is a preparation that can moisturize and protect the skin. Glycerin and sorbitol are humectants often used in cream preparations and have a large percentage in the cream preparation's formula so that they can affect the physical properties of the cream. This study aims to obtain the optimum composition range of glycerin and sorbitol and determine the effect of glycerin and sorbitol as humectants on the physical properties and stability of the hand sanitizer cream with Centella asiatica (L.) extract. The composition optimization was done using a factorial design method on two factors and two levels using the Design Expert 13 (free trial) application. The data on the physical properties and stability of the cream were statistically analyzed using a two-way ANOVA test at a 95% confidence level. The results of qualitative phytochemistry screening showed that the extract contained triterpenoid. The average test of physical properties and stability of physical properties meet the desired criteria: cream type O/W, viscosity 120–170 dPa.s., spreadability of 5-7 cm, shift of spreadability, and shift of viscosity below 10%. The optimum area shows that the formulas F1, FB, and FAB meet the desired criteria.
Standardization of Snakehead Fish (Channa striata) Concentrates Obtained from Sungai Itik Village, Kubu Raya District, West Kalimantan Aulia, Yunita Hananda; Andrie, Mohamad; Wintari , Wintari
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 2: September 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i2.26746

Abstract

Standardization is the method of identifying properties based totally on superb parameters to advantage the identical diploma of satisfaction. it has been proven that vitamins decided in snakehead fish (Channa striata) from herbal assets can be implemented as a possibility to hasten the recuperation of wounds. With the assistance of the techniques of freeze drying, this examination sought to set up the standardization of snakehead fish pay attention from Sungai Itik Village in Kubu Raya Regency, West Kalimantan as an uncooked material for prescribed drugs that treat wounds. Standardization carried out on concentrate samples consisted of specific and non-specific parameters. Specific parameters consist of organoleptic, water-soluble essence content, protein, and albumin. While the non-specific parameters tested were moisture content, ash content, acid-insoluble ash content, and drying shrinkage. The test results showed that the water content contained in snakehead fish was 7.21% ± 0.165, ash content was 10.47% ± 1.06, acid insoluble ash content was 1.40% ± 0.115, water-soluble essence content was 77.10% ± 0.54, dry shrinkage rate was 13.973% ± 0.193, the protein was 99.49% and albumin was 7.03 g/dl. The standardization parameters have not met all the tests so it can be said that snakehead fish concentrate has not met the standard and has not been standardized for natural wound healing medicinal ingredients.
Optimization of Liquid Shampoo Formula from Chia Seed Oil (Salvia hispanica L) Using the Simplex Lattice Design Method Amalina, Faidatul; Rahmayanti, Mayu; Afrizal, Muhammad; Nastiti, Ginanjar Putri; Syarifuddin, Sadli
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 2: September 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i2.28081

Abstract

Hair is one of the most essential parts of the human body, both men and women; one of the problems with hair that often occurs is hair loss. Chia plants contain sebum gland-stimulating agents with a keratin protein concentration of 23%. The sebaceous glands play a role in facilitating the growth of hair follicles so that hair can thrive and prevent hair loss. This research aims to determine the optimum composition of the prediction formula using Design Expert software and the physical characteristics and stability of liquid shampoo preparations. Optimization was carried out using Design Expert 13 software with two material components, namely HPMC and SLS, and two responses, namely viscosity and foam height. The optimum formula obtained was subjected to characteristic tests and stability tests. The stability test was carried out using the cycling test method by storing the preparation at temperatures of 4◦C and 40◦C for 48 hours. The results of the prediction formula show that component X1 is 0.589307% and X2 is 9.41069%. The one-sample t-test showed that the results were not significantly different at p>0.05 in the two responses. Testing of the optimum formula's physical characteristics and physical stability meets the reasonable requirements for organoleptic tests, homogeneity tests, viscosity tests 414,80±9,94 cPs, foam height tests 7,060±0,11 cm, and pH tests 7,39±0. The 8th run is the optimum formula with a composition of X1 0.589307% and X2 9.41069 % meets the requirements for good physical characteristics tests and physical stability tests.
Assessing Direct Medical Costs and Quality of Life In Elderly Patients Using High-Alert Medications at Wongsonegoro Hospital Supadmi, Woro; Endang Darmawan; Rizky Budi Santoso; Sri Sulistyorini
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 2: September 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i2.30368

Abstract

High Alert Medications (HAM) are drugs that pose a significant risk of causing harm to patients if used incorrectly. This study aimed to evaluate the direct medical costs and quality of life of elderly patients aged 60 years and above using HAM at Wongsonegoro Hospital. An observational prospective cohort study design was employed, utilizing both secondary and primary data collection methods. Secondary data included patient demographics, medication usage, and direct medical costs obtained from hospital records and the finance department. Primary data on quality of life were gathered using the European Quality of Life 5 Dimensions (EQ-5D-5L) questionnaire. A total of 25 elderly patients were identified as users of HAM, with a gender distribution of 48% male and 52% female; 64% of these patients were aged between 60 and 70 years. The most prevalent medical condition among participants was diabetes mellitus, affecting 44% of one group and 32% of another. Sodium Chloride (NaCl) 500 mL infusion at a concentration of 3% was the most frequently administered medication (27.5%). The average direct medical cost for elderly patients using HAM was IDR 4,255,050. Additionally, the quality of life assessment revealed that 20% of patients experienced significant challenges in self-care activities. These findings highlight the impact of HAM on healthcare costs and quality of life among elderly patients, emphasizing the need for careful monitoring and management strategies to mitigate risks associated with high-alert medications.

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