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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 60 Documents
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Search results for , issue "Vol 2, No 1 (2015)" : 60 Documents clear
Effect of Centella asiatica Leaves on Gastric Ulcer in Rats Mariska, Ester; Sitorus, Trully D.; Rachman, Januarsih A.
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Althea Medical Journal

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Abstract

  Background: Gastric ulcer is disruption of gastric mucosal integrity due to lack of smaller defensive factors (e.g. mucus levels) than gastric aggressive factors. Centella asiatica is a traditional medicine that contains triterpenoids and flavonoids. The objective of this study was to analyze the effect of ethanol extract of Centell aasiatica leaves for preventing gastric mucus level reduction of aspirin-induced gastric ulcer model in rats and compared it to misoprostol.Methods: An experimental laboratory study using 24 rats that were divided into 4 groups. Group I (negative control) received carboxymethy cellulose (CMC) solution, group II (positive control) received CMC and aspirin 450mg/kg, group III (tested group) received Centella asiatica 400 mg/kg and aspirin 450 mg/kg, group IV (compared group) received misoprostol 72μg/kg and aspirin 450mg/kg for three days. Then the rats were laparatomied and their gastric mucus levels were measured. The results were statistically analyzed by Independent T-test.Results: The mean levels of gastric mucus of group I, II, III, IV, respectively were 0.112; 0.035; 0.537; 0.455 optical densities per gram of tissue. The statistical test suggested a significant difference between the positive control group and tested group. Moreover there is no significant difference between the tested group and compared group.Conclusions: Centella asiatica leaves can prevent gastric mucus level reduction of aspirin-induced gastric ulcer model in rats and has similar effect in gastric mucus level with misoprostol.Keywords: Centella asiatica, gastric mucus, gastric ulcer, misoprostolDOI: 10.15850/amj.v2n1.444 
Malnourished Under-Five Children Feeding Practices in Cipacing Village 2012 Herawati, Dewi Marhaeni Diah; Kadi, Fiva Aprilia; Fujianti, Shinta Tresna
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

   Background: Maternal parenting, especially feeding practices, is very important in childhood period and may affect the child’s nutritional state. Proper nutrition affects the growth and development of children. The aim of this study is to describe parenting feeding practices in malnourished under-five children.Methods: A descriptive study on 43 mothers with malnourished under-five children aged 12−59 months was performed in Cipacing Village, Jatinangor, Sumedang during the periode of October−November 2012. Results: The composition of children based on their malnutrition status and description on good and poor parenting were presented in the result. Twenty two children (51.2%) were severely under nourished, 18 children (41.9%) were under nourished, and 3 children (7%) experienced overweight. Good maternal parenting was identified in child nurturing (86%), feeding frequency (93%), feeding style (62.8%), and situation of feeding (74.4%) while poor maternal parenting was observed in feeding time (55.8%) and types of food given (51.2%). Conclusions: Maternal parenting plays an important role in children nutrition status.Keywords: Children, feeding practice, malnutrition, maternal parentingDOI: 10.15850/amj.v2n1.435 
Knowledge Level of Pregnant Women in Cipacing Village on Nutrition and Benefits of Colostrums Reddy, Haviz; Fatimah, Siti Nur; Zulvayanti, Zulvayanti
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

   Background: Colostrums are the only natural food that is healthy for newborn infants since colostrums contain proper nutrition needed for infants’ growth. This study aimed to reveal the knowledge level of pregnant women on nutrition and benefits of colostrums. Methods: This study used descriptive cross-sectional method on 73 pregnant women in Cipacing village, Jatinangor district, Sumedang Regency, West Java, from October 18 to November 14, 2012. A questionnaire was used. Results: The results showed that the characteristics of these pregnant women were as follows: 20-35 years old (53.4%), most were middle school graduates (42.5%), most were unemployed (72.6%), and some claimed to have never given birth before (37,0%). Mostly, the knowledge level of these pregnant women was in the category of “favorable” (84.9 %). The knowledge level with the highest percentage (100%) came from pregnant women aged above 35 years old, college graduates, employed as private employees, civil servants, or self-employed, as well as having three biological children or more. Conclusions: Sustained health promotion and counseling programs are needed to maintain already-favorable knowledge level; thus pregnant women’s knowledge on nutrition and benefits of colostrums can be applied and can also encourage these women themselves to provide colostrums for their newborn infants.Keywords: Benefits of colostrums, Jatinangor, nutrition, women’s knowledge level    DOI: 10.15850/amj.v2n1.422 
Level of Knowledge about Hypertension in Cilayung Village District Jatinangor, Sumedang Qisthi, Dian; Wiwaha, Guswan; Martakusumah, Abdul Hadi; Setiawati, Elsa Pudji
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

  Background: Hypertension known as a silent killer because it is often asymptomatic and causes target organ damage. Prevention of hypertension and its complications are pharmacological and non-pharmacological therapy, making holistic knowledge of hypertension is paramount to establish good behavior. This is needed by hypertensive and non-hypertensive individuals. Therefore, the study was conducted to identify any knowledge level differences between hypertensive and non-hypertensive groups. Methods: Respondents were 116 Cilayung residents equally divided in hypertensive and non-hypertensive groups. Respondent’s blood pressure was measured and they completed questionnaires during October 2012. This is an observational analytic cross-sectional study with chi-square test.Results: The respondents’ characteristics in both groups dominated by females, aged 50-59 years, housewives, with elementary school background. Most respondents in both groups had sufficient knowledge about hypertension in general, but for knowledge about risk factors, treatment, and complications were still not enough. The result of the chi-square test was not significant with P=0.676. It was due to distributed health promotion and non-matched respondents’age.Conclusion: There is no difference in level of knowledge about hypertension between both groups in Cilayung.Keywords: Differences, hypertension, level of knowledge DOI: 10.15850/amj.v2n1.449 
Anti-inflammatory Effect of Trigona spp. Propolis in Restricting Edema Volume Nurhayati, Wulantika; Dewi, Vycke Yunivita Kusumah; Djajakusumah, Teguh Marfen
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Althea Medical Journal

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Abstract

  Background: Inflammation is a normal response that potentially harmful if it is uncontrolled. On the other hand, it is necessary to find an alternative anti-inflammatory as most anti-inflammatory drugs available nowadays still have adverse effects. Trigona spp. propolis is one of the potential anti-inflammatory alternatives because of its flavonoid, especially caffeic acid phenethyl ester, which is known as an active compound in anti-inflammatory process. This study aimed to understand the anti-inflammatory effect of Trigona spp. prolisin reducing edema volume in rat’s paw.Methods: An experimental study was performed on 20 male wistar rats. The rats were divided into control and experimental groups with 10 rats in each group. Control group was treated by propylene glycol 1 ml/day and experimental group was treated by Trigona spp. propolis 200 mg/kg body weight/day. The inflammation was induced by subcutaneous injection of λ-carrageenan 1% at plantar one hour after the treatment. Edema volumes were measured by plethysmometer every hour at 1 to 6 hours and once at 24 hours after induction. The difference in edema volumes was calculated in percentage. This study was conducted during October 2012 at the Pharmacology and Therapy Laboratory, Faculty of Medicine, Universitas Padjadjaran Bandung.Results: The increase of edema volume (in percentage) in control group and Trigona spp. propolis treated group are 100.64±32.22 and 56.46±20.38 respectively (p value=0.000). Multiple comparisons using Dunnet and Duncan post hoc test showed significant differences that were observed at 3, 4, 5, and 6 hours after inflammatory induction.Conclusion: Trigona spp. propolis has an anti-inflammatory effect in reducing edema volume in rat’s paw. The most significant effect was observed at 3, 4, 5, and 6 hours after inflammatory induction. Trigona spp. propolis might have a potential to be developed as a future anti-inflammatory drug.Keywords: Edema volume, inflammation, propylene glycol, Trigona spp, propolisDOI: 10.15850/amj.v2n1.440 
Correlation between Folate Intake during Pregnancy and Preterm Labor in Mothers with 0-9 Months Old Babies Stefanus, Gufi George; Fatimah, Siti Nur; Achmad, Eppy Darmadi
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Althea Medical Journal

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Abstract

 Background: Nutritional factors such as folate intake are important during pregnancy. Satisfying nutritional needs of pregnant mothers is necessary to avoid complications during pregnancy such as preterm labor, High infant mortality rate in Indonesia is still high. This study  aimed to study the relationship between folate intake during pregnancy and preterm labor.  Methods: This study used a cross-sectional analytic approach by using semi-quantitative Food Frequency Questionnaire, as an instrument on mothers with 0−9 months old babies living in the villages of Sayang and Hegarmanah, Jatinangor, Sumedang, Indonesia. Results:  Ninety mothers participated in this study. The result indicated that 25.55% respondents had low folate intake and high incidence of preterm labor (16.67%). Significant association was found between folate intake during pregnancy and preterm labor (p=0.019). Maternal age was not a confounding factor in this study. Conclusions: There is an association between folate intake during pregnancy and preterm labor in mothers living in the villages of Sayang and Hegarmanah, Jatinangor, Sumedang, Indonesia.Keywords: Babies 0−9 months, folate, preterm laborDOI: 10.15850/amj.v2n1.431 
Green Tea and its Effect on Hemostasis Measured by Thrombelastography Chua, Bryant Alyzandyr Eumhyn; Sitorus, Trully D.; Dalimoenthe, Nadjwa Zamalek
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

Background: Increasing health problems may come from changes in lifestyle including stressful lifestyles, high calorie diets, and lack of physical activity. Those may also lead to an increase occurrence of abnormal hemostasis. Green tea has been well known for its many benefits, including its antithrombotic effect. The aim of this study was to determine whether the consumption of green tea actually affects hemostasis and to measure changes in hemostatic parameters after its consumption.Methods: A preliminary explorative study was conducted on 3 healthy female subjects aged between 21 to 22 years old for 8 weeks from October to November 2012 in Jatinangor, Sumedang, Indonesia. The subjects were subjected to initial thrombelastography analysis and started drinking green tea twice a day after meals. The solution was made by steeping a teabag in 250ml water of 70°C for 2 minutes. After 8 weeks, another thrombelastography analysis was performed to the subjects. Results: Pre- and post-intervention results of the analysis were averaged and compared according to the parameters. The results of this study showed prolonged R (Reaction-time) and K (K-time), decreased α (angle) and MA (Maximum Amplitude), and increased LY30 (lysis at 30 minutes), showing an overall reduction in coagulability. Conclusions: The consumption of green tea twice a day for 8 weeks affects hemostasis with hemostatic parameters measured by thrombelastography show differences before and after consumption.Keywords: Green tea, hemostasis, thrombelastographyDOI: 10.15850/amj.v2n1.426
Basic Training of Student’s Outdoor Club Increases Muscle Mass after Five Weeks of Exercise in Males Salsabila, Novie; Chaidir, M. Rizal; Setiawan, Setiawan
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

   Background:  Aerobic and anaerobic exercises, may lead to increase muscle mass. The aim of this study was to determine the change in muscle mass during basic training of students’ outdoor club.Methods: This was an observational analytic study to college students who joined basic training of students’ outdoor club for 19 weeks. Subjects consisted of 17 male and 15 female students, measured  five times consecutively by using Body Fat/Hydration monitor scale, with Bioelectrical Impedance Analysis principle. Data collection was performed five times,  from February to July 2012 in Bandung. Statistical analysis was processed using Analysis of Variance (ANOVA).Results: The result in males showed the mean 43.35±3.15 on the initial measurement. The muscle mass further increased significantly after five, ten, fifteen, and nineteen weeks of exercise (43.73±3.18 (p<0.05); 44.07±2.97 (p<0.05); 44.08±2.84 (p<0.05); 44.72±2.78 (p<0.05); all data vs 43.35±3.15) respectively. In females, there was increased of muscle mass although not all were statistically significant. The baseline was 37.77±2.00 with increased muscle mass after five, ten, fifteen, and nineteen weeks of exercise (37.78±2.06 (p>0.05); 38.08±1.67 (p>0.05) ; 38.23±1.52 (p>0.05) ; 38.61±1.52 (p<0.05) vs 37.77±2.00) respectively.Conclusion: Basic training of student’s outdoor club increases muscle mass significantly after five weeks of exercise in males, but not in femalesKeywords: Basic training, Bioelectrical Impedance Analysis, hypertrophy, muscle mass, students outdoor clubDOI: 10.15850/amj.v2n1.445 
Role of Exclusive Breastfeeding in Preventing Diarrhea Rohmah, Hanifah; Hafsah, Tisnasari; Rakhmilla, Lulu Eva
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

  Background: Breast milk has protective factors for infants’ digestive tract. Infants are vulnerable to diseases, one of which is diarrhea. This cross-sectional study was designed to determine the relation between the proportion of diarrhea in infants and the administration of exclusive breastfeeding in Jatinangor.Methods: This study was an observational study. Data on mothers with 6 months old infants were collected from Jatinangor Primary Health Center (PHC) infant records. The inclusion criteria applied were infants born in April 2012, alive, and living in Jatinangor subdistrict. One hundred and seventy one infants were recorded in April of 2012 in the PHC data. Thirty five were excluded because they were not born in April 2012. Another 45 were excluded because they were not permanent residents of Jatinangor subdistrict, while 4 infants died, and 23 had incomplete data. Therefore, only 66 infants were included as study subjects. Those infants came from 12 villages in the subdistrict of Jatinangor. Data collection was then performed using a questionnaire to the parents during the period of 21–31 October 2012.Results: From 66 infants, the proportion of diarrhea was 66.7%. Only 27.3% of all infants received exclusive breastfeeding. There was a difference in the proportion of diarrhea between infants who were exclusively breastfed and those who were not. Exclusive breastfeeding also reduced the risk of diarrhea (OR= 0.26, 95% CI 0.08–0.83).Conclusions: There is a relation between the proportion of diarrhea in infants and exclusive breastfeeding in Jatinangor. Breastfeeding has a protective effect against diarrhea in infants.Keywords: Diarrhea, exclusive breastfeeding, infants DOI: 10.15850/amj.v2n1.436 
Description of Posner Schlossman Syndrome Patients in Bandung, Indonesia during the Period of August 2009 to July 2011 Arunasalam, Kavitha; Tjahjaningtyas, Erna; Ekowati, RA.Retno
Althea Medical Journal Vol 2, No 1 (2015)
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Abstract

   Background: Posner-Schlossman Syndrome (PSS) is also known as Glaucomatocyclitic Crisis. It is a non–genetic, often misdiagnosed, and rare disease characterized by recurrent unilateral episodes of markedly elevated intraocular pressure which occurs simultaneously with mild inflammation of the uvea. The underlying cause of this disease is still unknown. This syndrome usually affects those who are 20 to 50 years old. The aim of this study was to perform a descriptive study on subjects diagnosed with PSS at the National Eye Centre Cicendo Eye Hospital Bandung Indonesia. Methods: The method used was a descriptive study carried out on subjects diagnosed with PSS at the National Eye Centre Cicendo Eye Hospital Bandung, Indonesia during the period of August 2009 to July 2011.Results: Of 31 patients, 19 (61.3%) female patients participated in the study, 12 (38.7%) aged 31–40 years, 9 (29.0%) had recurrences. All (100%) complained of blurred vision, 24 (77.4%) with accompanying vision of rainbow halo surrounding light in, and 22 (71%) had headache. A total of 27 (87.1%) patients suffered from the disease unilaterally. After treatment, 17 (54.8%) patients’ visual acuity improved and 20 (64.4%) patients’ intraocular pressure (IOP) were in normal range. Conclusions: PSS mostly affects females. The most prevalent age range is 31–40 years. Most are affected unilaterally. All of them present with the symptom of  blurred vision. Visual acuity and IOP are in normal limit after treatment.Keywords:  Eye vision, Posner Schlossman Syndrome, National Eye Centre Cicendo Eye HospitalDOI: 10.15850/amj.v2n1.421 

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