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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 61 Documents
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Search results for , issue "Vol 2, No 4 (2015)" : 61 Documents clear
Correlation between Body Mass Index and Body Fat Percentage Ilman, Muhammad; Zuhairini, Yenni; Siddiq, Amillia
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Body mass index (BMI) has been used to determine the nutritional status which is classified into low, normal, overweight or obese. The BMI only shows a comparison of height and weight instead of body composition which consists of fat mass and fat–free mass. Most of people assumed that BMI overage means fat mass overage as well, yet it does not occur in all cases. This study was conducted to measure the correlation between BMI and body fat percentage.Methods: An analytical study was conducted to 100 male and female students respectively from Universitas Padjadjaran Jatinangor batch 2009 to 2013. The body  weight was measured using scales , whereas the body height was measured using stature meter. The body fat percentage was measured using Bioelectrical Impedance Analysis (BIA). The BMI was calculated by dividing the body weight in kilogram divided by body height in meter square. Data was collected from September to October 2013 and analyzed by Pearson’s correlation test.Results: The mean of BMI in male students and female students were 22.56 and 21.35 respectively. The body fat percentage was 16.44 for men and 28.09 for women. Correlation score between BMI and fat mass in male students were 0.853 and female students are 0.834.Conclusions: There is a strong and positive correlation between BMI and body fat percentage both in male and female students in Universitas Padjadjaran Jatinangor. Among this population, BMI can still be used todetermine body fat percentage. [AMJ.2015;2(4):575–8] DOI: 10.15850/amj.v2n4.642
Association of Obesity, Parity, and History of Knee Injury with Knee Osteoarthritis in Female Triyadi, Ade; Pramudiyo, Riardi; Iwan A. R., Januarsih
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Osteoarthritis is the most joint disorder among elderly. There are a lot of risk factors of knee osteoarthritis. Obesity and high frequent of parity can increase the load on knee joint. Knee injury also decreases the stability of knee joint on bearing body load. This study was conducted to observe the association of obesity, parity ≥3 times and history of knee injury with the occurrence of knee  osteoarthritis in female aged >50 years old.Methods: Case control design was chosen in this study. Female patients with age >50 years were recruited by consecutive sampling from rheumatology clinic at Dr. Hasan Sadikin General Hospital Bandung. Data were collected from August to September 2013. Minimal sample size was 60 samples calculated by rule of thumb formula. Obesity was measured by body mass index (BMI). Parity and history of knee injury were assessed by questionnaire. Those variables were analyzed by logistic regression method.Result: Obesity did not associate with knee osteoarthritis in this study, p=0.549 (odd ratio (OR) 1.32, 95% confidence interval (CI) 0.52–3.32). Parity was associated with knee osteoarthritis in this study p=0.001 (OR 4.7, 95% CI 1.89–11.68). History of knee injury was associated with knee osteoarthritis in this study, p=0.001 (OR 6.19, 95% CI 2.01–18.99).Conclusions: Parity ≥3 times and history of knee injury were associated with the occurrence of knee osteoarthritis. Obesity was not associated with the occurrence of knee osteoarthritis. [AMJ.2015;2(4):492–6] DOI: 10.15850/amj.v2n4.633
Knowledge and Risk of Osteoporosis among Pre-elderly at Cipacing Village Jatinangor District in 2014 Ramdhani, Muhammad; Mulyadi, Dicky; Arisanti, Nita
Althea Medical Journa Vol 2, No 4 (2015)
Publisher : Althea Medical Journa

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Abstract

Background: Osteoporosis is a disease characterized by abnormal loss of bone density resulting inbones that are brittle and liable to fracture. Most cases of fracture in the world are due to osteoporosis. InIndonesia, the prevalence of osteopenia (early osteoporosis) and of osteoporosis are relatively high. Oneof the causes of this situation is the low level of public knowledge about how to prevent osteoporosis. Thisstudy was conducted to identify the knowledge and risk of osteoporosis among pre-elderly at CipacingVillage Jatinangor District in 2014.Methods: This descriptive study was conducted at Cipacing Village Jatinangor District to 160 respondentswho were classified as pre-elderly (aged 45-59 years) and assessed on knowledge and risk factors forosteoporosis through questionnaire-guided interviews after the informed consent was obtained.Thecollected data were presented using frequency distribution.Results: A total of 100 respondents (62.5%) had good knowledge about osteoporosis-related information,including definitions, causes, risk factors, signs and symptoms, impacts, and prevention. Most respondents,79 respondents (49.4%), are at risk for osteoporosis.Conclusions: Knowledge of osteoporosis among pre-elderly at Cipacing Village Jatinangor District arelargely classified into “good knowledge” category. [AMJ.2015;2(4):608–14]
The Effect of Breadfruit Leaves Infusion on Acute Renal Failure Rat model Abstract Hardani, Muhamad Risdan; Sastramihardja, Herri S.; Afiatin, Afiatin
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background : Empirically, breadfruit (Artocarpus altilis) leaf has been used as traditional medicine for several diseases, such as acute renal failure. This research is aimed at finding the effects of breadfruit leaf infusion on blood creatinine levels in rats to model acute renal failure.Methods : This research is an experimental study, using 30 male wistar rats, weighing 150–250 g, divided into 5 groups. The first group is a negative control and the second group is a positive control. Groups 2–5 were induced with Gentamicine and peroxicam for 7 days, and then groups 3–5 given infusion of breadfruit leaf in different doses for 7 days, and then blood creatinine levels were tested at the 15th day. This data was analyzed using a multiple comparison Dunnett T3 test because this data is not homogenous. This research was done in pharmacology laboratorium universitas padjadjaran from Oktober–November 2012.Result : Bases on average creatinine levels of 0.62, 0.87, 0.98, and 0.87 mg/dL observed for the diffetent groups, it was statistically show that significantly different creatinine levels, differing by 0.038 (p < 0.05) were observed for the control group and the group which was given an infusion of breadfruit leaf.Conclusion : It can be concluded that infusions of breadfruit leaf do have an effects on blood creatinine levels in acute renal failure.Key words : acute renal failure, breadfruit leaf, creatinine  DOI: 10.15850/amj.v2n4.527
Relationship between Exclusive Breastfeeding and Nutritional Status of Infants Aged 12 months Selvina, Sheilla; Fadlyana, Eddy; Arisanti, Nita
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Exclusive breastfeeding has a high nutrient content to fulfill the nutritional needs of infants aged 0−6 months. The aim of this study was to describe thenutritional status of infants aged 12 months and to determine the relationship of exclusive breastfeeding and nutritional status of infants aged 12 months in Pos Pelayanan Terpadu (Posyandu) Cipacing Village Jatinangor.Methods: A cross sectional study was carried out to 102 mothers with infants aged 12 months in Posyandu Cipacing Village from September to October 2013. The infants’ body weight were weighed with weight scales which had been calibrated and the body length were measured with the Seca 210 baby length measuring mat, then the mother was interviewed with a questionnaire which had been validated to inquire about the exclusive breastfeeding history. The Fisher exact test was used to assess relationship between both variables.Results: There were 81.3% of infants with good nutritional status and 83.3% of infants who did not get exclusive breastfeeding. The analysis test showed that the p-value of relationship between exclusive breastfeeding and nutritional status was 0.458 with odds ratio 3.343.Conclusions: Most of the infants are in good nutritional status although they do not get exclusive breastfeeding. Consequently, there is not a significant relationship between exclusive breastfeeding and nutritional status. [AMJ.2015;2(4):534–40] DOI: 10.15850/amj.v2n4.638
Correlation between Six-Minutes’ Walk Test and Quality of Life in Heart Failure Patients Erwinanto, Erwinanto; Andean, Rudolf; Rahmani, Syifa
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: The problem of heart failure patient relates with reduced functional capacity and eventually leads to declined quality of life (QoL). Improved QoL may not relate to better functional capacity since QoL is influenced by patient’s expectation to the on-going treatment. This study was conducted to investigate the correlation between  six-minutes’ walk test (6MWT) as a measure for functional capacity and QoL of heart failure patient in Dr. Hasan Sadikin General Hospital.Methods: This cross sectional study involved 32 patients who were on planned visit at the outpatient clinic of Dr. Hasan Sadikin General Hospital Bandung from September to October 2013. Subjects were chosen using consecutive sampling. The correlation of 6MWT and QoL assessed using modified Minnesota Living and Heart Failure Questionnaire (MLHFQ) was analyzed through Pearson’s correlation test.Results: There was a significant correlation between distance covered in 6MWT and QoL (r=-0.354, p<0.05).The mean of six-minute walk distance was 277.96 (±42.17) and mean of QoL score was 33.41 (±7.88). In accordance with the findings in previous studies, this study revealed correlation between the distance obtained in 6MWT and the QoL score in heart failure patient.Conclusions: There is correlation between 6MWT and quality of life in outpatients with heart failure at Dr. Hasan Sadikin General Hospital. [AMJ.2015;2(4):469–73] DOI: 10.15850/amj.v2n4.629
Knowledge and Attitude of Senior High School Students in Jatinangor towards Sexually Transmitted Infections in 2013 Hendrana, Aisyah Riseta Aini; Mutyara, Kuswandewi; Rowawi, Rasmia
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Sexually transmitted infections (STIs) are major health problem. Until today, the prevalence of STIs is still high and the incidence is increasing. Almost half of STIs new cases occur in adolescents andyoung adults. It is assumed that there is a positive correlation of knowledge about STIs with attitude and practices; therefore, giving proper information of STIs to adolescents could influence their safe sexual practices, and further, it can prevent STIs to occur. The objective of this study is to discover knowledge and attitude of senior high school students in Jatinangor towards STIs.Methods: This descriptive study was conducted in Sekolah Menengah Atas Persatuan Guru Republik Indonesia (SMA PGRI) Jatinangor and Sekolah Menengah Atas Negeri (SMAN) Jatinangor from May to September 2013. Questionnaires were completed by 278 respondents selected by stratified cluster random sampling.Results: More than half respondents had poor knowledge about STIs (56.5%) while 53.2% of the respondents had positive attitude towards STIs. Most mentioned choices as the information source of STIs were teacher(66.5%), followed by television/radio (45.3%), friends (37.8%), newspaper/magazine (21.2%), mother (16.2%), sibling (7.2%), and father (6.5%). Conclusions: More detail information about STIs is needed by adolescents as a way to encourage safe sexual practices. Teacher and parents are expected to be the source information of STIs while mass media can alsobe used to educate adolescents. Education on STIs for teachers is also needed since they are as the main source for educating the adolescents. [AMJ.2015;2(4):568–74] DOI: 10.15850/amj.v2n4.655
Familial Predisposition of Primary Dysmenorrhea among Senior High School Girl Students Sharlini, Prema; Sukandar, Hadyana; Fadil, Ryadi
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Dysmenorrhea is a common female reproductive problem in women of active reproductive agewhich is characterized by menstrual pain or cramps in a women’s lower abdomen or back. Dysmenorrhea can be classified into primary and secondary. One of the associated risk factor of primary dysmenorrhoeais the family history, however the study on the family history of primary dysmenorrhea with recurrent  menstrual pain is limited. This study was conducted to identify the correlation between family history and primary dysmenorrhea in high school girls.Methods: This cross sectional study was conducted at several senior high schools in Jatinangor from April−June 2013. One hundred and sixty two students were included in this study. The sample size was calculated based on the unpaired−dichotomous variable for the two−sided formula. A self administered questionnaire was distributed to the senior high school girl students who were in their menarche age, menstrual cycle characteristics, presence or absence of dysmenorrhea, severity of pain and presence dysmenorrhea in mothers and in sisters were inquired. Data were analyzed using chi square test.Results: Overall, there were association between positive family history and primary dysmenorrhea among the students with (p<0.001). The prevalence of dysmenorrhea in the students was 92.6% with 95% confidence interval which was 87.5−95.7%. The prevalence rate was 67.9% in mothers with 95% confidence interval which is 60.4−74.6% and 80.2% prevalence of primary dysmenorrhoea in sisters with 95% confidence interval which is 73.4−85.6%.Conclusions: There is a significant association between positive family history and primary dysmenorrhea.[AMJ.2015;2(4):579–83] DOI: 10.15850/amj.v2n4.643
Profile of Hand Compartment Syndrome in Dr. Hasan Sadikin General Hospital, West Java, 2008−2012 Manogaran, Kajendaran; Hidajat, Nucki Nursjamsi; Soenggono, Arifin
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Compartment syndrome is a serious disorder caused by elevated pressure in a muscle compartment that can progress to muscle and nerve damage. This disorder can happen to anyone but more frequently in young adults. The occurrence frequency of hand compartment syndrome is relatively low. The aim of this study is to identify the profile of compartment syndrome in patients handMethods: A descriptive study was perfomed to 15 cases that were collected from medical records from 2008-2012, in Dr. Hasan Sadikin General Hospital. The profile of the case consisted of age, sex, symptoms and signs, etiology, facsiotomy schedule after admission, length of stay and patient’s outcome. The collected data were presented using tables.Results: The study showed that 12 out of 15 cases were males and 7 out of 15 cases were 20−39 years oldpatients. The common clinical findings were swelling, pain, limited range of motion and normal sensibility. The faciotomy procedure was conducted 1 day after the admission with length of stay more than 1 week. The patients condition were improved after operation. Conclusions: Hand compartment syndrome is a rare case, mostly affects younger adults and male. Most of the symptoms and signs are swelling, limitation of movement, pain in the location area with normal sensibility. The faciotomy procedure is conducted 1 day after admission. The length of stay is more than 1 week with an improved outcome. [AMJ.2015;2(4):497–501] DOI: 10.15850/amj.v2n4.634
Solanum muricatum Aiton Juice as A Hepatoprotective Agent in Wistar Rats Induced With Carbon Tetrachloride Yang, Justine Sim Wei; Istriati, Istriati; Rostini, Tiene
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Liver participates in various metabolic processes in human body. Exposures to toxins such as carbon tetrachloride (CCl4) results in hepatocyte destruction and release the cell contents. Enzymes such as serum glutamic pyruvic transaminase (SGPT) were used as a parameter to diagnose liver damage. Pepino (Solanum muricatum Aiton) contains antioxidants that protect liver from hepatoxicity. The aim of this experiment is to determine the effect of pepino in protecting the hepatocyte from hepatotoxic effect of CCl4.Methods: A total of 16 Wistar rats used as the subject were divided into Control and Therapeutic Group. The Control group was induced with CCl4 but was not given pepino juice. Meanwhile, the Therapeutic Group was given pepino juice for 10 days. For induction of hepatotoxicity, CCl4 10% was given at a dosage of 2.0 ml/kg intra-peritoneal. Each Wistar rat in Therapeutic Group was given 1.0 ml of 300 g/ml pepino juice via oral feeding. Spectrophotometer with adjusted wavelength of 340 nm was used to measure SGPT level of the Wistar rats and statistical T-test was used to analyze the data.Results: Wistar rats in Therapeutic group showed a larger decrease (6898.9 IU/L–79.1 IU/L) in SGPT level compared to the Control group (6469.8 IU/L–418.5 IU/L). The SGPT level of the Wistar rat in Therapeutic group reached normal baseline (50 IU/L–150 IU/L). The significance of the experiment was supported by the T-test, P-value <0.05Discussion: Pepino juice had antioxidants that protect the hepatocyte of Wistar rats from free radicals. The synergistic action of antioxidants and hepatocyte regeneration of Wistar rats in Therapeutic group caused a decrease in SGPT level. Therefore, the experiment concluded that pepino juice at the dosage of 300 g/ml has hepatoprotective effect.Key words: Carbon tetrachloride, hepatotoxicity, Pepino, Solanum muricatum Aiton, SGPT DOI: 10.15850/amj.v2n4.484

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