cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
chiefeditor.amj@gmail.com
Editorial Address
Gedung Rumah Sakit Pendidikan Unpad/Pamitran Unpad (Teaching Hospital Building) Faculty of Medicine Unpad, 3rd Floor Jl. Prof. Eyckman No. 38, Bandung, 40161, Indonesia
Location
Kota bandung,
Jawa barat
INDONESIA
Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
 83   84   85   86   87 
Forced Expiratory Volume in 1 Second and Forced Vital Capacity in Bronchial Asthma Patients in Relation with Asthma Exercise Atika Andianti; Vita Murniati Tarawan; Hendarsyah Suryadinata
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1781

Abstract

Background: Aerobic physical activity is one of the non-pharmacology management approaches of asthma. The Asthma Foundation of Indonesia (Yayasan Asma Indonesia, YAI) has designed an aerobic physical activity for people with asthma, known as Asthma Exercise. Asthma exercise is expected to increase the overall functional capacity of the lungs. One way to measure lung function is by measuring the score of forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). The objective of the study was to explore the difference in FEV1 and FVC between bronchial asthma patients with and without asthma exercise. Methods: This study involved asthma patients from the Bandung Asthma Association (Perhimpunan Asma Bandung, PAB) who did asthma exercise (n=28), and as control patients from the Pulmonology Clinic in Dr. Hasan Sadikin General Hospital were selected who did not do asthma exercise. The research data used were primary data from the spirogram examination. Asthma patients were selected based on inclusion and exclusion criteria. This research used unpaired numerical comparative analytical hypothetical tests with a cross-sectional design.Results: The study showed the mean of FEV1 and FVC in the group with asthma exercise (1.6107±0.3780L and 2.0396±0.3465L) was higher than the group without asthma exercise (1.3750±0.4702L and 1.7164±0.4632L). Statistical difference test using independent t-test indicated a score of p=0.044 for FEV1 and p=0.005 for FVC between the two groups.Conclusions: There are significant differences in FEV1 and FVC between bronchial asthma patients with and without asthma exercise. Furthermore, asthma exercise is recommended for asthma patients to improve their lung function. 
Bleeding Volume, Blood Pressure, and Consciousness Level in Association with the Mortality Rate among Patients with Intracerebral Hemorrhage at Dr. Soetomo General Hospital, Surabaya Mohammad Pratama Jauhar Putra; Achmad Firdaus Sani; Puji Lestari; Mohammad Saiful Ardhi
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1751

Abstract

Background: Intracerebral hemorrhage is one of the deadliest acute conditions. The volume of bleeding and its location are factors that alter consciousness level, leading to death. This study aimed to explore the association between bleeding volume, blood pressure, and consciousness level with the mortality rate among patients with intracerebral hemorrhage, so proper treatment and diagnosis can be conducted efficiently.Methods: This was an observational retrospective study conducted from October 2018–July 2019. Bleeding volume, blood pressure, consciousness level, and mortality as the outcomes of the patients with intracerebral hemorrhage were evaluated. Consciousness level was determined by using the Glasgow Coma Scale score. Data were collected from the medical record of intracerebral hemorrhage patients of the Neurologic Department in Dr. Soetomo General Academic Hospital Surabaya in the period of 2016. The Chi-square analysis method was used to determine the correlation between variables.Results: In total, 51 medical records were retrieved, and the majority of the patients were in the 45–60 years old group (54.9%). The mortality during hospitalization was 17.6% with most of them (82.4%) had bleeding volume less than 30 cc. Interestingly, the bleeding volume correlated with the consciousness level (p=0.001) and the outcome of the patients (p=0.02). The blood pressure shows a correlation with the volume of bleeding (p=0.009).Conclusions: Bleeding volume and consciousness level as determined by the Glasgow Coma Scale score show significant correlations with the mortality rate in patients with intracerebral hemorrhage. 
Cancer Antigen 125 Serum Level in Head and Neck Diffuse Large B-Cell Lymphoma Igor Togar Hutabarat; Agung Dinasti Permana; Yussy Afriani Dewi
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1788

Abstract

Background: Diffuse Large B-Cell Lymphoma (DLBCL) is the most common subtype of the Non-Hodgkin Lymphoma (LNH). Until now, lactate dehydrogenase (LDH) is the only tumor marker to assess DLBCL progression; however, increased LDH is a relatively non-specific biomarker. Cancer antigen 125 (CA-125) serum level have been used as a tumor marker in ovarian cancer. The aim of this study was to explore the possible role of CA-125 serum level as a tumor marker in head and neck DLBCL.Methods: This was an observational descriptive study among consecutively sampled DLBCL patients. CA-125 serum level examination was carried out (ADVIA Centaur CA-125II) and described along with the clinical characteristics of DLBCL patients.Results: DLBCL was mostly observed in males (54.05%), most often in the 55-65 year age group (51.3%), with stage 1 DLBCL was the most prevalent (71.9%). The mean CA-125 serum level was 22.9 U/ml and increased in patients with advanced DLBCL.Conclusions: Increased CA-125 serum level in DLBCL, especially at advanced stages, suggests that CA-125 serum level may be of benefit as a tumor marker in the head and neck DLBCL. Further study is in need to explore the role of CA-125.1.       Kementerian Kesehatan Republik Indonesia. Data dan kondisi penyakit limfoma di Indonesia. InfoDatin Pusat Data dan Informasi Kementerian Kesehatan RI. 2015 [cited 2020 March 18] Available from: https://www.kemkes.go.id/resources/download/pusdatin/infodatin/infodatin-limfoma.pdf2.       Dwianingsih EK, Indrawati, Hardianti MS, Malueka RG , Iswar RR, Sutapa S, et al. Histopathological features of lymphoma in Yogyakarta, Indonesia. Asian Pac J Cancer Prev. 2016;17(9):4213–16.3.       Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. Riset Kesehatan Dasar (RISKESDAS) 2013. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI; 20134.       Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014; 32(27):3059–67.5.       Ziepert M, Hasenclever D, Kuhnt E, Glass B, Schmitz N, Pfreundschuh, et al. Standard International prognostic index remains a valid predictor of outcome for patients with aggressive CD20+B-cell lymphoma in the rituximab era. J Clin Oncol. 2010;28(14):2373-2380.6.       Gutiérrez A, Martínez-Serra J, Barceló B, Sampol A, Vinas L, Gonzales G, et al. Prognostic value of serum CA125 levels in diffuse large B-cell lymphoma: potential role of a new sex and age adjusted reference value. Int J Lab Hematol. 2010; 32(6 Pt 2): 582–9.7.       Dilek I, Ayakta H, Demir C, Meral C, Ozturk M. CA 125 levels in patients with Non-Hodgkin lymphoma and other hematologic malignancies. Clin Lab Haematol. 2005;27(1):51–5.8.       Memar B, Aledavood A, Shahidsales S, Ahadi M, Farzadnia, Raziee HR, et al. The prognostic role of tumor marker CA-125 in B-Cell non-Hodgkin’s Lymphoma. Iran J Cancer Prev. 2015;8(1):42–6.9.       Garg S, Goyal B. Evaluation of CA-125 as a prognostic marker in patients with Non-Hodgkin’s lymphoma. International Journal of Medical and Health Research. 2017;3(4):13–5.10.   Paoli CJ, Bach BA, Quach D, Tsai KT, Wong B, Kallich J. Performance status of real-world oncology patients before and after first course of chemotherapy. The Journal of Community and Supportive Oncology. 2014; 12(5):163–70.11.   Yadav C, Ahmad A, D’Souza B, Agarwal A, Nandini M, Prabhu KA, et al. Serum lactate dehydrogenase in Non-Hodgkin’s lymphoma: a prognostic indicator. Indian J Clin Biochem. 2016;31(2):240–2.
Spirometric Values of Patients with Chronic Obstructive Pulmonary Disease in Dr. Hasan Sadikin General Hospital Bandung Christopher Rinaldi; Rudolf Andean; Irma Ruslina Defi
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1687

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a frequently underdiagnosed disease. Definitive COPD has been diagnosed using spirometry to evaluate pulmonary function. This study aimed to explore the spirometric values of COPD patients to aid in the diagnosis of COPD.Methods: A descriptive study was conducted in Dr. Hasan Sadikin General Hospital Bandung from October to November 2015. Data on patients diagnosed with COPD, aged 40 to 60 years old, were collected during the year 2014 prior to ethical clearance. Spirometry values consisted of forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio were taken from the medical records.Results: Sixty-eight COPD patients, consisting of 48 males and 20 females, were included of with most were classified as moderate COPD. The FEV1 was 49.72±17.79, whereas the FVC was 55.90 (range 22.80–96.03), and the FEV1/FVC ratio was 0.70±0.12. Most patients were classified into moderate COPD who had FEV1 between 50 and 80% of normal as GOLD 2 standard.Conclusions: Even though patients seem to have no symptoms, spirometric values may show a silent insufficient lung function affecting patients’ daily life.
Cerebral Palsy Parents’ Knowledge, Attitude, and Behavior at Dr. Hasan Sadikin General Hospital Bandung 2014 Maria Christina Shycha Moenardi; Ellyana Sungkar; Dewi Hawani
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1790

Abstract

Background: Cerebral palsy (CP) as a non-progressive syndrome of motor function and posture disturbance is caused by the abnormality or damage on the brain during its development. Children with CP usually have motor, sensory, communication, and intellectual disturbances. Medical rehabilitation is important; however, the environmental aspect is also crucial for their development. Parents as their caregivers may have good knowledge to assist their children during rehabilitation. This study aimed to explore the knowledge, attitude, and behavior among parents with CP children.Methods: This study was descriptive quantitative study and conducted at the Physical Medicine and Rehabilitation Clinic of Dr. Hasan Sadikin General Hospital Bandung during September to October 2014. Parents of CP children were asked to complete a questionnaire that was specifically designed for this study after their consent was obtained.Results: From a total of 31 parents, 51.6% had good knowledge about CP; 58.1% had good attitude toward CP children, and 51.6% had good behavior while taking care of their children.Conclusions: The majority of parents with CP children have good knowledge, attitude, and behavior towards CP children. The knowledge of risk factors of cerebral palsy are poor, therefore, it is necessary for doctors and therapists to provide more education sessions on the risk factors and other related topics about cerebral palsy.
Correlation between Hemoglobin Concentration and Cardiorespiratory Fitness in Adolescent Sportsmen Billy Leoprayogo; Venna Venna; Ignatio Rika Haryono; Francisca Tjhay
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1847

Abstract

Background: Sport is a physical activity that increases human body oxygen demand. Hemoglobin has a major role to fulfill the oxygen demand. The body capacity to fulfill the increasing oxygen demand could be seen as cardiorespiratory fitness. Sportsmen have a high cardiorespiratory fitness due to the intensity and frequency of training. This study aimed to explore how hemoglobin concentration affects the cardiorespiratory fitness of adolescence sportsmen. Method: This study used a cross-sectional approach. The sampling started in October – November 2019. Sample of this study were 15-19 years old male badminton and basketball sportsmen at Jakarta and Bogor (n=72). Hemoglobin concentration measured with a digital hemoglobinometer which used an azide-methemoglobin method. VO2max estimated with a beep test. FITNESSGRAM® Performance Standard was used for the classification of cardiorespiratory fitness. All measurement’s ethical issues had been approved. The result of hemoglobin concentration and cardiorespiratory fitness was processed by SPSS program with Spearman and Kruskal-Wallis analysis method. Results: There was a correlation between hemoglobin concentration and cardiorespiratory fitness (p = 0.001, p < 0.05). Spearman analysis showed there was a weak correlation (r = 0.38) between hemoglobin concentration and cardiorespiratory fitness. Kruskal-Wallis analysis showed there was a meaningful mean difference in hemoglobin concentration on cardiorespiratory fitness groups (p = 0.005, p < 0.05). Conclusion: The mean of the hemoglobin concentration on the Healthy Fitness Zone (HFZ) cardiorespiratory group was higher than on the Need Improvement (NI) group and the Need Improvement within Health Risk (NI-HR) group. 
Bleeding Patterns among Severe Hemophilia A and B Patients in West Java Muhammad Mufakkirul Islam; Susi Susanah; Amaylia Oehadian
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1941

Abstract

Background: The clinical manifestations of hemophilia A (HA) and hemophilia B (HB)are quite similar; however, the bleeding characteristics of these two hemophilia types have been reported to be different. This study aimed to explore the bleeding patterns among patients with severe HA and severe HB.Methods: A cross-sectional study was conducted among patients with severe HA and HB registered at the West Java Indonesian Hemophilia Society. The inclusion criteria were patients with severe hemophilia diagnosed for at least one year. The bleeding patterns included bleeding episodes and bleeding types. The Mann-Whitney test was used to compare bleeding episodes and a chi-square test for bleeding types.Results: In total, 158 severe HA patients and 21 severe HB patients were included with a median bleeding frequency per patient per year for HA and HB was 24 (range 0–48) and 24 (range 5–48), respectively. The bleeding types in HA and HB were ecchymosis (69% vs. 66.7%), hematoma (62.7% vs. 61.9%), hemarthrosis (99.4% vs. 100%), epistaxis (46.8% vs. 38.1%), gum bleeding (87.3% vs. 95.2%), intracranial hemorrhage (15.2% vs. 9.5%), multiple hematomas (36.7% vs. 47.6%), hemarthrosis-hematoma (61.4% vs.61.9%), and hemarthrosis-ecchymosis (69% vs. 61.9%). However, there was no significant difference in all types of bleeding between HA and HB.Conclusions: There is no difference in the pattern of hemorrhage between severe HA and severe HB in West Java. However, the bleeding phenotypes in hemophilia has considerable implications in the therapeutic process. Further research is needed to optimize the treatment regimens.
Implementation of Comprehensive Geriatric Assessment in Elderly-Friendly Public Health Centers and General Public Health Centers in Bandung Astri Keli; Sharon Gondodiputro; Nita Arisanti
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1923

Abstract

Background: Comprehensive Geriatric Assessment (CGA) is a comprehensive, multi-dimensional biopsychosocial examination. The CGA is conducted at the primary health facility such as the public health centers (Pusat Kesehatan Masyarakat, Puskesmas); categorized as Eldery-Friendly Public Health Centers (Puskesmas Santun Lansia), a puskesmas where one of its programs provides health care for the elderly, and Puskesmas in general, where there is no specific program for the elderly. The purpose of the study was to analyze the difference between Puskesmas santun lansia and Puskesmas in providing CGA.Methods: A comparative analytical study was carried out from August to November 2019, involving Puskesmas Santun Lansia (n=6) and puskesmas (n=12) in Bandung City. From each Puskesmas, two elderly were selected and observed for the CGA. The assessment consisted of the identity of the elderly, anamnesis, vital sign examination, physical examination, assessment of nutritional status, functional, psychosocial, social, cognitive, and mental assessment. The collected data were analyzed using the Chi-square or Fisher’s exact test.Results: This study showed that there was no difference between Puskesmas Santun Lansia and Puskesmas in the CGA, except in the simple nutritional anamnesis (p=0.003), anamnesis of the symptoms or signs of the dysfunction of the organ system (p=0.034), and body mass index measurement (p=0.009).Conclusions: The CGA is not well implemented in both Puskesmas. In the future, both of the Puskesmas should enhance their knowledge and skills to provide the CGA as mentioned in the regulation of the Minister of Health No. 67/2015. 
Relationship between Calcification on Mammography and Human Epidermal Growth Factor Receptor 2 (HER-2) Expression in Breast Carcinoma Zulfadli Zulfadli; Hari Soekersi; Raden Yohana; Birgitta M. Dewayani
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1963

Abstract

Background: Breast carcinoma shows over-expression of Human Epidermal Growth Factor Receptor 2 (HER-2) in 18 to 20% of the cases. This type of cancer is very progressive and has a poor prognosis. This study aimed to determine the association between the calcification on mammography with HER-2 expression in breast carcinoma as a marker of breast carcinoma aggressiveness.Methods: This was an analytic observational study with a case-control design. Patients with breast carcinoma at the Department of Radiology and Department of Anatomical Pathology of Dr. Hasan Sadikin General Hospital Bandung from July–September 2019 were enrolled in this study. Samples were consecutively collected. The association of calcification on mammography and HER2 expression was analyzed using the Chi-square test.Result: In total, 40 patients were included, consisting of 20 individuals with HER-2 positive and 20 individuals with HER-2 negative. The youngest was 40 years old and the oldest was 73 years old. Statistical test results showed that there was a significant association between calcifications in mammography and HER-2 expression (p-value = 0.0001, OR 13.22; 95% CI 2.7–62.6).Conclusions: There is a significant association between calcification on mammography and HER-2 expression in breast carcinoma, suggesting that positive calcification mammography was 13.22 times higher in patients with HER-2 positive compared to patients with negative calcifications.
Daily Living Performance in Schizophrenic Patients in Correlation with Positive and Negative Symptoms Nurul Amelia Rahayu Putri; Tuti Kurnianingsih; Santi Andayani
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1870

Abstract

Background: Schizophrenia is a global mental health problem. Patients experience problems in their daily-living performance. Positive and negative symptoms have been part of characteristics of schizophrenia that are absent in normal individuals, which include a distinctive fundamental distortion of thoughts and perception (positive symptoms) and loss of normal function and behavior (negative symptoms). This study aimed to explore the correlation between positive and negative symptoms and daily-living performance in schizophrenia. Methods: A correlative analytical study with a cross-sectional approach was conducted using secondary data from the Outpatient Clinic of the Mental Hospital of West Java Province. Data on socio-demographic characteristics were collected and positive and negative symptoms as assessed by Positive and Negative Syndrome Scale or Subscales (PANSS) were correlated with the activities of daily living (ADLs) and instrumental activities of daily living (IADLs), which were further analyzed by Spearman’s correlation test.Results: In total, 31 male schizophrenic patients aged between 24-45 years old. There was no significant correlation between ADLs dependency levels and both positive and negative symptoms. However, there was a significant correlation between IADLs function and positive symptoms and not with negative symptoms.Conclusions: Even though no correlation was identified between ADLs dependency levels with positive and negative symptoms, the ADLs and IADLs assessments should be considered as important tools for schizophrenic patients for rehabilitation to improve daily-living functioning.

Page 85 of 107 | Total Record : 1068

 83   84   85   86   87 

Filter by Year

2014 2025


Reset
Filter By Issues
All Issue Vol 12, No 3 (2025) Vol 12, No 2 (2025) Vol 12, No 1 (2025) Vol 11, No 4 (2024) Vol 11, No 3 (2024) Vol 11, No 2 (2024) Vol 11, No 1 (2024) Vol 10, No 4 (2023) Vol 10, No 3 (2023) Vol 10, No 2 (2023) Vol 10, No 1 (2023) Vol 9, No 4 (2022) Vol 9, No 3 (2022) Vol 9, No 2 (2022) Vol 9, No 1 (2022) Vol 8, No 4 (2021) Vol 8, No 3 (2021) Vol 8, No 2 (2021) Vol 8, No 1 (2021) Vol 7, No 4 (2020) Vol 7, No 3 (2020) Vol 7, No 2 (2020) Vol 7, No 1 (2020) Vol 6, No 4 (2019) Vol 6, No 3 (2019) Vol 6, No 2 (2019) Vol 6, No 1 (2019) Vol 5, No 4 (2018) Vol 5, No 3 (2018) Vol 5, No 3 (2018) Vol 5, No 2 (2018) Vol 5, No 2 (2018) Vol 5, No 1 (2018) Vol 5, No 1 (2018) Vol 4, No 4 (2017) Vol 4, No 4 (2017) Vol 4, No 3 (2017) Vol 4, No 3 (2017) Vol 4, No 2 (2017) Vol 4, No 2 (2017) Vol 4, No 1 (2017) Vol 4, No 1 (2017) Vol 3, No 4 (2016) Vol 3, No 4 (2016) Vol 3, No 3 (2016) Vol 3, No 3 (2016) Vol 3, No 2 (2016) Vol 3, No 2 (2016) Vol 3, No 1 (2016) Vol 3, No 1 (2016) Vol 2, No 4 (2015) Vol 2, No 4 (2015) Vol 2, No 3 (2015) Vol 2, No 3 (2015) Vol 2, No 2 (2015) Vol 2, No 2 (2015) Vol 2, No 1 (2015) Vol 2, No 1 (2015) Vol 1, No 2 (2014) Vol 1, No 2 (2014) Vol 1, No 1 (2014) Vol 1, No 1 (2014) More Issue