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INDONESIA
Journal of Medical Physics and Biophysics
Published by Himpunan Fisika Medis dan Biofisika Indonesia
ISSN : 23552727     EISSN : 23552719     DOI : -
Core Subject : Health, Science,
Medicine & Pharmacology Physics
Journal of Medical Physics and Biophysics is a gold open-access journal and serves as official publication media of the Indonesian Association of Physicists in Medicine, IAPM (Aliansi Fisikawan Medik Indonesia, AFISMI). JMPB publishes articles with the general concern on the application of physics in medicine and the biological system. The role of physics highlighted in the journal can be of theoretical, experimental, or clinical nature. Review and original articles in radiation oncology, diagnostic and interventional radiology, nuclear medicine, biomaterial, physical biology, physical modeling of biological system, and other related sciences are welcome. Any opinions stated on the articles published in JMPB are those of the author(s) and do not necessarily reflect the policy of IAPM/AFISMI unless otherwise stated.
Arjuna Subject : -
Articles 69 Documents
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The effects of wound dressings on the dose at surface and depth of maximum dose (dmax) for photon and electron beam radiotherapy Raizulnasuha Binti Ab Rashid; Norhayati Dollah; Reduan Abdullah; Wan Nordiana W. Abd Rahman
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The presence of wound dressing at the patients’ skin surface during radiotherapy treatment may potentially alter the dose at surface and shift the dose distribution at depth. In this study, the effects of different types of wound dressing to the radiotherapy treatment were investigated. The dose measurement at surface and dmax were done using different energy of photon and electron beams at 100 cm source to surface distance (SSD). Markus parallel plate ionization chamber and solid water phantom were used to quantify the dose with the dressing types used are Alderm +Plus, Actisorb Plus 25, Gauze and Duoderm CGF Extra Thin. The results show increment of surface dose up to 93.9% by wet gauze for photon beams and around 21% of dose increase for electron beams. Effects of dressing to the the dose at dmax indicate shift of dose distribution towards surface with reduction of dose around 10 % in wet condition for photon beam and up to 35 % for electron beams. Significant changes in surface dose and dose at dmax due to the wound dressing indicate the presence of wound dressing during radiotherapy need to taken in account in calculating dose to the target.
A Preliminary Study of Percentage Breast Glandularity of Bangladeshi Women from Mammography Data Meherun Nahar; Md. Sazzad Hossain; Abdus Sattar Mollah; Mir Md. Akramuzzamsan
Journal of Medical Physics and Biophysics Vol 3, No 1 (2016)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

 Abstract: A study was made to estimate mammographic breast glandularity in Bangladeshi women from generic radiographic data. The primary objective of this study was to determine the percentage of breast glandularity of Bangladeshi women which will affect mean glandular dose (MGD) during diagnostic mammography. The secondary objective was to evaluate some of the factors affecting women’s glandular tissue. A fitted equation was applied for 80 women who underwent diagnostic mammography. The values of compressed breast thickness (CBT), mAs and target/filter combination, were collected for 80 women ranging in age from 21 to 70. The average breast glandularity of the study sample was 43.7% ± 17.35%. Breast glandularity was found to decrease with breast thickness and age. No significant variation of mean glandularity has been found with Body Mass Index (BMI).
Point dose measurement on center and peripheral target for stereotactic treatment using Helical Tomotherapy Hi-Art Laras Ati Nur Fatimah; Nuruddin Nasution; Wahyu Edy Wibowo; Supriyanto Ardjo Pawiro
Journal of Medical Physics and Biophysics Vol 5, No 1 (2018)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) using tomotherapy were advanced radiotherapy technique with prescribing high dose on the peripheral target to get as steep as possible fall-off dose criteria on the target. These technique need an accurate and high precision treatment delivery also passing the criteria for patient specific quality assurance. Point dose measurement was a simple verification to ensure these goals. However, there are many issues for point dose measurement with ionisation chamber related to the problem of high dose gradient area on the peripheral target. Therefore, the purpose of this study was to verify the assessment criteria of ±3% discrepancies for center and peripheral target measurement. The work has been done by point dose verification for 11 patient with brain cancer using Helical Tomotherapy Hi-Art. Point dose measurement were done on the center and peripheral PTV, also brainstem for organ parameter in the off-axis area, using Exradin A1SL. The measurement results show that highest discrepancy compared to the dose plan for center and peripheral target reach 1.95% and 2.81%, respectively. The Higher discrepancies shows for peripheral target compared to the center target measurement. The measurement on the brainstem show a highest discrepancies reach 5.29%. This result occur because of the off-axis area of the brainstem location. In conclusion, the center and peripheral target measurement are meet the criteria ±3% by the dose plan with peripheral target measurement shows higher discrepancies influences by volume averaging effect and lack of particle equilibrium of the condition related to the chamber size.
Radiation Dose Measurements at Radiosensitive Organs in Overcouch Barium Enema Examination Farah Mardhiah Janudin; Akmal Sabarudin; Khadijah Mohamad Nassir
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The objectives of this study were to measure the radiation dose on the skin surface at the selective radiosensitive organs and to compare its distributions on an anthropomorphic phantom during an overcouch barium enema examination. This study was also designed to suggest the suitable exposure parameters for the projections in overcouch barium enema examination. The eye lens, thyroid, breast, and gonad were selected in this study and the dose was measured using thermoluminesence dosimeters (TLD) with computed radiography system. Five radiographic projections were carried out including supine, prone, right lateral decubitus, left lateral decubitus, and prone-angled view (Hampton’s view) to demonstrate the entire lower gastrointestinal tract. The highest skin surface dose (SSD) was received at the gonad followed by breasts, lens, and thyroid, corresponding to 2.49 ± 1.32 mGy, 0.14 ± 0.08 mGy, 0.057 ± 0.032 mGy, and 0.044 ± 0.04 mGy, respectively. The exposure parameters for tube voltage in a range of 75 kVp to 80 kVp, and tube current between 36 mAs and 40 mAs can provide proper image quality for abdominal region for an individual with average body weight.
Metode line profile: pendekatan terhadap evaluasi kuantitatif citra Computed Radiography thoraks pada pasien pediatrik Halimah Harfah; Lukmanda Evan Lubis; Kristina Tri Wigati; Djarwani Soeharso Soejoko
Journal of Medical Physics and Biophysics Vol 5, No 1 (2018)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Tujuan dari penelitian ini adalah untuk menunjukkan fisibilitas metode line profile sebagai metode evaluasi kuantitatif citra computed radography thoraks pasien pediatrik. Sampel berupa 36 citra thoraks pediatrik yang terdiri dari 26 citra thoraks normal dan 10 citra thoraks abnormal, diperoleh dengan menggunakan sistem CR. Line profile dibuat dengan menggunakan perangkat lunak imageJ dan dikuantisasi menggunakan fortran 90. Setiap line profile diberi enam perlakuan (metode) yang berbeda, yakni tanpa modifikasi nilai piksel (metode I), modifikasi nilai piksel menjadi kontras region of interest (ROI) tulang (metode II), modifikasi nilai piksel menjadi kontras ROI thoraks (metode III), normalisasi rentang nilai piksel (metode IV), normalisasi rentang nilai piksel dan modifikasi kontras ROI tulang (metode V), serta normalisasi rentang nilai piksel dan modifikasi kontras ROI thoraks (metode VI). Verifikasi metode dilakukan dengan menggunakan coefficient of variation (CoV). Metode terbaik dipilih dan digunakan sebagai acuan line profile normal yang akan dibandingkan dengan line profile citra abnormal. Untuk membandingkan secara kuantitatif line profile normal dan abnormal, diskrepansi (δ) digunakan sebagai parameter. Hasil penelitian menunjukkan bahwa metode line profile dengan menggunakan normalisasi rentang nilai piksel adalah metode yang memiliki fisibilitas untuk membedakan citra normal dan abnormal. Dari metode ini, kelainan dengan δ terkecil adalah bronchitis dan δ terbesar adalah effusion. Penelitian lanjutan diperlukan untuk meningkatkan fisibilitas metode ini untuk kasus abnormalitas lain.
Injectable Bone Substitute Synthesized from Mangrove Snail Shell Yessie Widya Sari; Reza Pahlevi Rudianto; Nur Aisyah Nuzulia; Sulistioso Giat Sukaryo
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The need for biomaterials tends to increase especially in the field of medicine caused by cases of increasing bone damage. The biomaterial that is being developed for bone implants is hydroxyapatite (HAp). The high value of imports of bone-replacement biomaterials in Indonesia is conidered as a thoughtful problem because of the high price, therefore the development of biomaterials used as a substitute for bone derived from natural materials. In this study, HAp in the form of an injectable bone substitute (IBS) was syntehsized. IBS is a bone-substitute material in the form of a suspension. IBS can be applied by injection to reach deeper areas of bone defects and be able to adjust the shape of bone or tooth defects properly. HAp was synthesized in this study with assistance of microwave irradiation. Mangrove snail shell was used as calcium sources. Furthermore, this study indicated that HAp synthesized from mangrove snail shell had a high potency to be developed as IBS.
Evaluation of Radiation Workers Occupational Doses for Newly Established Medical Center NORIN Nawabshah in Pakistan Abdul Razaq; Muhammad Waqar; Quratulain Soomro; Muhammad Ali Javaid
Journal of Medical Physics and Biophysics Vol 3, No 1 (2016)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

AbstractThe purpose of this study is the evaluation of radiation doses received by radiation personnel in newly established medical Centre, Nuclear Medicine Oncology and Radiotherapy Institute Nawabshah (NORIN) Pakistan. In this study the annual dose data of workers for the year 2013 and 2014 in different sections will be analyzed using different statistical methods and results. It will be discussed that how we careful in occupational radiation dose and comparison with national and international organization will be done to know that the facility in NORIN for radiation protection is reasonable and satisfactory.
Lateral setup error analysis of dosimetric impact for nasopharynx carcinoma using intensity modulated radiotherapy treatment Syarifatul Ulya; Nuruddin Nasution; Wahyu Edy Wibowo; Supriyanto Ardjo Pawiro
Journal of Medical Physics and Biophysics Vol 5, No 1 (2018)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Patients with nasopharyngeal carcinoma have been analyzed for lateral setup error. Systematic and randomized inter-fractional setup errors were evaluated in 48 patients with this case. Based on these errors, the margin was drawn from CTV to obtain the delineation of PTV structure, called PTV margin. MVCT system in tomotherapy has been used to get the number of error with four-degree direction setup. Moreover, the biggest error direction value was evaluated with in 6 patients and analyzed at D98 in each PTV and OARs. The result of PTV margin for the lateral, longitudinal, vertical, and rotation was 4.91 mm, 4.27 mm, 3.37 mm and 3.53 mm, respectively. According to the result of the PTV margin, a lateral direction showed the biggest value of error. So, achievable dose coverage of PTVs on the effect of the lateral shift were 87.04%, 60.19%, and 50% for 2, 4 and 6 mm, respectively. Furthermore, OAR dose in the right position is increasing with larger shift setup direction.
Computer Aided Diagnosis (CAD) for mammography with Markov Random Field method with Simulated Annealing optimization Ni Larasati Kartika Sari; Prawito Prajitno; Lukmanda Evan Lubis; Djarwani Soeharso Soejoko
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Mammography is the most effective technique to detect breast abnormalities. In most cases, mammograms are evaluated by radiologists. However, diagnosis performed radiologist has a lot of limitations. Computer Aided Diagnosis (CAD) with various methods had been developed to help radiologist in evaluating mammograms. This research developed CAD for mammography based on image segmentation using Markov Random Field with Simulated Annealing optimization (MRF/SA). We combined MRF/SA method with various preprocessing algorithms, such as median filter, histogram equalization, and CLAHE (Contrast Limited Adaptive Histogram Equalization). MRF/SA without any filter and contrast enhancement was also performed. A total of 210 mammograms with normal and abnormal findings were used. Abnormal category means mammogram with abnormalities findings whether in a form of benign lesion, malignant lesion, benign microcalcification or malignant microcalcification. ROC (Receiver Operating Characteristic) analysis was used to measure methods’ performance. The values of area under the ROC curve (AUC) for MRF/SA only, median filter + MRF/SA, histogram equalization + MRF/SA and CLAHE + MRF/SA are 0.731, 0.840, 0.798, and 0.746 respectively. Combination of median filter + MRF/SA has the highest AUC value indicated that this method has the best performance in distinguishing normal and abnormal images. Histogram equalization + MRF/SA has inferior AUC value compare to median filter + MRF/SA, but this combination has the highest sensitivity, 90.4%. This result shows that histogram equalization + MRF/SA is the most successful method in detecting abnormal images correctly.
Karakteristik berkas foton lapangan kecil setengah lapangan (half beam) dengan menggunakan wedge Elsa Angelina; Wahyu Edy Wibowo; Riana Dian Pertiwi; Supriyanto Ardjo Pawiro
Journal of Medical Physics and Biophysics Vol 5, No 1 (2018)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Penelitian ini bertujuan untuk mengetahui profil berkas foton lapangan kecil setengah lapangan (half beam) dengan menggunakan wedge yang dapat menjawab tantangan radioterapi tumor sino-nasal yang diketahui memiliki lokasi yang sangat kompleks. Pengukuran dilakukan dengan berkas foton 6MV menggunakan dosimeter film Gafchromic EBT3 yang dilakukan pada kedalaman 1.5 cm, 5 cm dan 10 cm untuk setiap lapangan penyinaran 0.8 × 0.8 cm2, 1.6 × 1.6 cm2, 2.4 × 2.4 cm2, 3.2 × 3.2 cm2 dan 4 × 4 cm2 dengan menggunakan physical wedge dengan besar sudut 15°, 30°, 45° dan 60° serta dilakukan variasi penyinaran yaitu daerah penyinaran wedge tipis dan tebal. Hasil pengukuran didapatkan bahwa nilai FWHM dan penumbra cenderung naik seiring dengan semakin dalamnya pengukuran. Selain itu, nilai FWHM cenderung lebih besar 1.59% saat daerah penyinaran wedge tipis. Penumbra memiliki rentang nilai 0.15 – 0.36 cm dengan anomali sebesar 80% (n=135) jika definisi penumbra merupakan jarak level isodosis 80% - 20% dan 0.24% (n=135) jika definisi penumbra merupakan jarak level isodosis 50% - 20%. Kesimpulannya, dari hasil pengukuran nilai deviasi FWHM dan penumbra (80% - 20%) terkecil masing-masing 0.92% dan 0.33 cm pada lapangan 0.8×0.8 cm2 wedge 60°, namun tidak ada hubungan yang pasti antara wedge dengan nilai FWHM dan penumbra pada lapangan kecil.

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