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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol. 13 No. 3 (2024): November 2024" : 6 Documents clear
Kanker Primer Multipel Metakronus pada Berbagai Organ: Kasus Serial Putriyuni, Anandia; Khambri, Daan
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2407

Abstract

Multiple primary cancer (MPC) is multiple tumors with synchronous or metachronous occurrence in the same individual. Metachronous tumors are defined as those that occur more than six months after the first tumor is diagnosed. It has been reported two serial cases with metachronous multiple primary cancers. One of the cases was triple metachronous, a combination that has never been previously reported. First case: A 58-year-old woman presented with a lump in her right breast and axilla. Histopathology found an invasive micropapillary carcinoma with many lymph node metastases. Two years later, the patient got a rectal mass biopsy with an adenocarcinoma diagnosis. In one month, the patient got a nodule on the right toe, and the result revealed squamous cell carcinoma with moderate to poorly differentiated. Second case: A 76-year-old woman presented a lump on her left cheek with keratinizing squamous cell carcinoma. The patient had a left breast nodule eight months later, and the diagnosis was invasive carcinoma of no special type. Both patients died within 1 year of the last diagnosis. We revealed two cases of primary cancers with different locations and histopathology. The causes of MPCs are unclear, but they may be related to various factors. Multiple primary cancer patients should be closely followed up for possible growth of other cancers. Interdisciplinary collaboration can guarantee the best possible diagnosis and treatment for the patient. Keywords:  metachronous, multiple, primary cancer
Stres Berhubungan dengan Kejadian Pityriasis Sicca (Ketombe) pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Semarang Amiroh, Ellya Umi; Krisnarto, Eko; Ratnaningrum, Kanti
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2413

Abstract

Pityriasis sicca is a common problem in Indonesian society that can be caused by various factors and the main cause is the fungus Pityrosporum ovale which causes rough and smooth scales. Objective: To prove the relationship between the degree of stress, age and gender with the incidence of Pityriasis sicca (dandruff) in students at the faculty of medicine Muhammadiyah University Semarang. Methods: This research used a cross-sectional design with a purposive sampling technique on students class of 2023 from the faculty of medicine at Muhammadiyah University Semarang. Primary data was obtained through filling out questionnaires and physical examination of respondents. Analysis of the age variable was carried out using the Mann-Whitney test and the gender and degree of stress variables used the Chi-square test. Results: From 112 respondents, it was found that age was not related to the incidence of Pityriasis sicca in students at the faculty of medicine Muhammadiyah University Semarang (p=0.185). Gender was not related to the incidence of Pityriasis sicca (p= 0.899). The degree of stress was related to the incidence of Pityriasis sicca (p=0.000). Conclusion: The degree of stress is related to the incidence of Pityriasis sicca, while age and gender are not related to the incidence of Pityriasis sicca.          Keywords:  dandruff, Pityriasis sicca, stress levels
Weil’s Disease dengan Gagal Ginjal Akut Amelia, Rizki; Fadrian, Fadrian
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2431

Abstract

Weil's disease is a severe leptospirosis characterized by multiorgan failure with symptoms of high fever, jaundice, kidney failure, liver necrosis, lung abnormalities, cardiovascular collapse, neurological changes, and bleeding. Acute kidney injury may occur in 20% to 85% of patients during the second phase of leptospirosis disease. It has been reported a 31-year-old male patient had a persistent high fever, pain in the muscles and joints throughout the body, especially in the muscles of both calves, headache, eyes and the whole body looked yellow, urinating like dark tea. The patient once fished in the river barefoot. Physical examination showed icteric sclera, ciliary injection, and temperature 38.9ºC. Laboratory examination of leukocytes 16,880/mm3, platelets 26,000/mm3, ureum 152 mg/dl, creatinine 6.8 mg/dl, direct bilirubin 15 mg/dl, indirect bilirubin 7.2 mg/dl, SGOT 192 U/L, SGPT 71 U/L. Urinalysis showed hematuria and proteinuria. Anti-leptospira IgM serology showed reactive results. On direct dark field microscopic examination of urine samples, fine spiral-shaped Leptospira bacteria were found. On ultrasound examination of the kidneys, the impression of both kidneys showed acute nephritis. The Modified Faine Criteria Score was 39, which suggests presumptive leptospirosis. The patient was treated with intravenous antibiotics Ceftriaxon 2x1 gram and hemodialysis. Keywords:  acute kidney injury, hemodialysis, leptospirosis, Weil’s disease
Pengaruh Aerobic Exercise Terhadap Aktivitas Serum Creatin Kinase Myocardial Band (CK-MB) pada Lansia Pasca Stroke Daba, Mariel; Fatria, Ilham; Padaallah, Ananda Patuh
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2433

Abstract

Stroke can cause changes in the heart, which are associated with excessive activation of the sympathetic nervous system as a response to damage occurring in the insular cortex. Cardiac biomarkers such as creatine kinase myocardial band (CK-MB) show increased levels in some patients with acute cerebrovascular accidents without direct cardiac injury. CK-MB activity has been found to increase in the early phase of patients with ischemic stroke, subarachnoid hemorrhage, and head trauma. Objective: To determined the effect of aerobic exercise on serum creatine kinase myocardial band (CK-MB) activity in elderly post-stroke patients. Methods: This was a pre-experimental study with a one-group pretest-posttest design. The study involved 16 elderly post-stroke respondents who received aerobic exercise using a static cycle at light to moderate intensity for 10-15 minutes, 2-3 times per week, over the course of 4 weeks. CK-MB activity was evaluated using the Enzyme-Linked Immunosorbent Assay (ELISA) method. Results: There was a significant effect of aerobic exercise on serum CK-MB activity in elderly post-stroke patients, with a p-value of 0.000 or p < 0.05. The mean serum CK-MB level increased to 29.43µL, while the mean serum CK-MB level decreased to 23.12 µL after receiving aerobic exercise with a static cycle for 4 weeks. Conclusion: Aerobic exercise using a static cycle at light to moderate intensity for 10-15 minutes, 2-3 times per week, over the course of 4 weeks, had a significant effect on serum creatine kinase myocardial band (CK-MB) activity in elderly post-stroke. Keywords:  aerobic exercise, static cycle, creatine kinase-myocardial band, stroke, elderly  
Manajemen Pemberian Diet DASH (Dietary Approach to Stop Hypertension) dengan Penambahan Buah Kurma (Phoenix dactylifera L.) pada Penderita Hipertensi Kronis dalam Kondisi Puasa: Case Report Adinda, Annida Azzah; Rahmawati, Ana Yuliah
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2439

Abstract

The Diet Dietary Approach to Stop Hypertension (DASH) diet limits sodium and saturated fat and is high in fiber and minerals that can help control blood pressure. Date fruits are high in fiber and contain minerals and polyphenolic compounds that can lower blood pressure along with the DASH diet. This report is to observe the effect of DASH diet with date fruit combination on blood pressure changes in chronic hypertensive clients under fasting conditions. The study design was a single case study design to observe the effect of DASH diet combined with date fruit on hypertensive patients in fasting conditions. Subjects are patients undergoing homecare nutrition or diet programs by a nutritionist. The intervention was carried out for five days. The procedures include nutritional screening and assessment, diagnosis and nutritional care planning, implementation of nutritional care, and monitoring and evaluation. Data were analyzed through a descriptive approach to describe changes in blood pressure. Respondents' food intake during the intervention reached >80% of needs. Sodium intake was <1500 mg/day and fiber was>20 g/day. Blood pressure before the intervention showed grade I hypertension, while blood pressure on day 1 to day 5 of the intervention showed normal. The DASH diet combined with the provision of dates can support the reduction of blood pressure in patients with hypertension. Keywords:  DASH Diet, date fruit, hypertension, fasting  
Peran Probiotik dalam Regulasi Kolagen dan Melanin: Systematic Review Badri, Amelia A.; Dewi, Ni Nyoman Ayu; Wahyuniari, Ida Ayu Ika
Jurnal Kesehatan Andalas Vol. 13 No. 3 (2024): November 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i3.2524

Abstract

Collagen and melanin production are two biological processes that are significant in determining the health and appearance of the skin. Collagen affects the elasticity, hydration, and overall appearance of the skin. Melanin protects the skin from damage caused by ultraviolet rays, but excessive production can lead to hyperpigmentation. Hyperpigmentation, dry skin, and wrinkles are signs of premature aging and can be caused by oxidative stress due to exposure to UV rays (photoaging). Probiotics are living microorganisms that provide health benefits when consumed in sufficient amounts and are currently gaining more and more attention as potential agents for skin health. This article reviews the role of probiotics in inhibiting melanogenesis through inhibition of tyrosinase cell activity and microphthalmia-associated transcription factor (MITF) expression. Probiotics can slow down collagen degradation due to sunlight by inhibiting the Metalloproteinase Matrix (MMP) activity and improve the skin's barrier function, reduce inflammation, and support a healthy skin microbiota. Recent studies show that the use of probiotics, both oral and topical, offers a natural and multifunctional approach to skin care. In conclusion, probiotics have promising potential as an ingredient for skincare, but more research is needed to understand the underlying mechanisms and ensure their safety and effectiveness in clinical applications. Keywords: hyperpigmentation, melanogenesis, photoaging, probiotics

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