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MEDISAINS
Published by Universitas Muhammadiyah Purwokerto
ISSN : 16937309     EISSN : 26212366     DOI : -
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
MEDISAINS: Jurnal Ilmiah Ilmu-ilmu kesehatan merupakan sarana penyebarluasan ilmu pengetahuan, riset, teknologi dan inovasi dibidang kesehatan yang diterbitkan tiga kali dalam setahun (April, Agustus dan Desember). Jurnal Medisains adalah jurnal peer reviewed dan Open-Access yang dikelola oleh Fakultas Ilmu Kesehatan Universitas Muhammadiyah Purwokerto dan di terbitkan dibawah Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) Universitas Muhammadiyah Purwokerto.
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Articles 9 Documents
 1 
Search results for , issue "Vol 22, No 1 (2024)" : 9 Documents clear
An innovative support pillow for diabetic foot wound care Suroso, Jebul; Zulfa, Aqilatun; Gumelar, Nanda Cikal; Soleha, Rama Nanda; Nuraeni, Siti; Febriyanti, Ika Putri; Santosa, Agus
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21428

Abstract

Background: Treating diabetic foot ulcers (DFU) sometimes takes a long time. During treatment, the patient's feet are usually given a cushion (such as a sleeping pillow or bolster) to make the wound seen. This way, some patients reported that their feet tingled because they were not positioned rightly for an extended period. So far, no unique pillow is available for this function. This pillow would help in treating DFU and should be comfortable for patients. Thus, it is essential to research designing such a product.Purpose: To develop and test a special pillow for treating DFU.Methods: This research adopts Research and Development (R&D). This research is divided into two stages: designing and developing and product testing.Results: This pillow is made of multiplex and foam, covered with Polyester fabric. It is 75mm in length and 45mm in width. It is equipped with a foot care area and waste storage tank. The test results showed that the score for comfort for the patients was 92%, while the score from the nurse was 88%.Conclusion:The pillow product helps the nurse conduct the DFU treatment and is comfortable for the patients. 
Spiritual relaxation therapy to improve sleep quality for nurses working shifts who experience sleep problems: a quasi-experimental study Prasetyo, Sudigdo Dwi; Mukhoirotin, Mukhoirotin
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.19834

Abstract

Background: Impaired sleep quality is a common problem experienced by nurses working shifts, and if not treated properly, it can impact their work performance and overall health. Spiritual Emotional Freedom Technique (SEFT) therapy has been proven to improve sleep quality. However, its effectiveness has never been studied in nurses who experience sleep disorders due to working shifts.Objective: To investigate the influence of spiritual relaxation therapy on sleep quality among nurses experiencing sleep disturbances due to shift work.Method: This is a Quasi-Experimental study with a pre-test-posttest control group design. A total of 38 nurses who experience sleep disorders due to working shifts were included in this study. The PSQI questionnaire was utilized as the instrument to measure sleep quality. Data analysis involved the Mann-Whitney test.Results: The average sleep quality before the intervention was in the mild category; after the intervention, most were in the good category. The results showed that the sleep quality of nurses who received spiritual relaxation was better than the control group (p<0.001).Conclusion: Spiritual relaxation therapy effectively improves the sleep quality of nurses experiencing sleep disturbances due to shift work.
Formulation and evaluation of antibacterial activity of hand sanitizers containing red betel (Piper crocatum) and white galangal (Alpinia galanga) extract Faridah BD, Faridah BD; Saputri, Lita Angelina; Fitriah, Iin Prima; Rahmawati, Lisa; Oktavia, Nike Sari; Armin, Fithriani
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21357

Abstract

Background: The COVID-19 outbreak has changed how people live worldwide, making hand hygiene a must, whether it involves hand sanitizer (HS). The majority of HS are made of alcohol. Several side effects of alcohol are dryness and allergies. Alternative natural ingredients and HS are needed. Red betel (Piper crocatum) and white galangal (Alpinia galanga) are familiar and easy to be found. These two plants have the potential to be the composition of HS because of their compounds, such as antioxidants, antibiotics, antifungals, and antivirals. However, there is a need for further research on their formulation and effectiveness in germ-killing.Purpose: To formulate and identify the antibacterial activity of HS containing red betel and white galangal extract.Method:  This research was an in vitro laboratory experiment with several steps, including extraction, specific and nonspecific tests, formulation, and antibacterial activity tests.Results: Red betel and white galangal leaves had been extracted at a concentration of 10% and formulated into HS. The HS containing 10% red betel extract produced an inhibition zone of 0 mm against E. coli and 1.05 mm against S. aureus, and the HS containing 10% White galangal extract produced an inhibition zone of 1.47 mm against E. coli and 1.40 mm against S. aureus.Conclusion:  The formulation of HS containing 10% of white galangal extract is more effective than the HS containing 10% of Red betel extract.
Develop a web-based system using the Naïve Bayes algorithm to predict asphyxia neonatal Arselatifa, Elviga; Sumarni, Sri; Kurnianingsih, Kurnianingsih
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.19531

Abstract

Introduction: Most cases of perinatal asphyxia are caused by conditions unrelated to labor. When asphyxia occurs during childbirth, it is usually caused by an obstetric emergency that was not detected during pregnancy. It is essential to prevent asphyxia by identifying the incidence of asphyxia during pregnancy. Several studies have been conducted to identify asphyxia problems developing by predictive models. However, there has been no development of a system for predicting birth asphyxia during pregnancy and carried out in primary health facilities.Purpose: Develop a web-based system using the Naïve Bayes (NB) algorithm to predict asphyxia neonatal using a dataset of antepartum risk factors in primary health facilities.Methods: This study employed research and development, which consists of 4 stages, namely literature study, development stage, expert validity, and trial.Results: A system that health workers in primary health facilities can use to predict asphyxia neonatal and recommend referrals for determining the place of childbirth has been successfully created. The system performance test predicted asphyxia neonatal with all NB evaluation values reaching more than 98%, and the prediction accuracy in the respondent test included in the High Accuracy category (MAPE value 9.06%).Conclusion: The development of a web-based system using the NB algorithm has been proven to be able to predict asphyxia neonatal and can be implemented for health workers as an effort to anticipate delays in handling cases of asphyxia neonatal because of the predicted results along with recommendations for focusing mothers with the risk of babies born asphyxia to find out possible childbirth places.
Butterfly hug therapy on reducing anxiety levels and stabilization hemodynamics in patient digital subtraction angiography Astuti, Anis Wiji; Rosyid, Fahrun Nur; Subrata, Sumarno Adi
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21484

Abstract

Background: Digital subtraction angiography can affect anxiety in patients so that it can worsen the patient's condition during catheterization, such as increased heart rate and breathing. One of the efforts to reduce anxiety that can improve hemodynamics is butterfly hug therapy. However, its effectiveness in reducing hemodynamic anxiety needs to be further investigated.Purpose: To evaluate butterfly hug therapy's effectiveness on anxiety and hemodynamics before digital subtraction angiography.Methods: This is a quasi-experiment study with a pretest-posttest control group design. Fifty-two respondents were selected using purposive sampling. A total of 26 respondents were given butterfly hug therapy, and 26 others were given standard therapy. The study implemented the Zung Self Rating Anxiety Scale Questionnaire and observation sheet. This research analysis uses the Independent T-test and Wilcoxon Test.Results: The anxiety level of the experimental group was lower than that of the control group (46.73 ± 2.08 vs. 53.84 ± 1.74; p<0.05). In hemodynamic stability (pulse, respiratory, and blood pressure) was stability than the control group (80.69 ± 2.44 vs. 89.11 ± 2.39; 20.65 ± 0.39 vs. 21.0 ± 0.53; 104.7 ± 1.46 vs. 109.5 ± 1.82; p <0.05).Conclusion: Butterfly hug therapy is effective in reducing anxiety and stabilizing hemodynamics among patients undergoing digital subtraction angiography.
In vivo study of celery (Apium graveolens L) extract for regenerating pancreatic β-cell Ismail, Dina Dewi Sartika Lestari; Kristianto, Heri; Setyoadi, Setyoadi; Maydinah, Anissa
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.20079

Abstract

Background: The celery plant (Apium graveolens L.) is a widely distributed herbal plant globally known for being a significant source of natural active products, including phenolic compounds and antioxidants demonstrating antidiabetic activity. Previous research findings have indicated the impact of celery leaf extract on reducing blood glucose levels. However, up to now, there is a dearth of research investigating the potential effect of celery leaf extract on the regeneration of pancreatic beta cells in mice with diabetes models.Objective: This study aims to determine the effect of the ethanol extract of celery leaves on the number of pancreatic cells in Streptozotocin (STZ)-induced mice.Method: This research method uses a randomized controlled group posttest only design. Experimental animals were divided into five groups, including a group of experimental animals in a healthy condition, the group with hyperglycemia, hyperglycemia group with celery extract at 200 mg/kg BW, hyperglycemia group with celery extract at 400 mg/kg, and hyperglycemia group with extract celery is 800 mg/kg BW. Termination was performed on day 60 after therapy and pancreas hematoxylin and eosin staining. They are counting the number of cells with a photo slide with 400x magnification in 5 fields of view—statistical analysis using One-Way ANOVA.Results: The study revealed that celery extract could increase the number of pancreatic cells compared to the control group (P<0.002). Notably, the highest increase in pancreatic cell count was observed in the group administered with 400 mg/BW of celery extract.Conclusion: Celery leaf extract effectively increased the number of beta cells in vivo.
The innovation of Wolbachia mosquito technology to control dengue hemorrhagic fever Kushartanti, Roro; Wijayanti, Aprin Wahyu
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21720

Abstract

Wolbachia is a bacterium that generally occurs naturally in 50% of insect species, lives in insect cells, and is passed from one generation to the next through insect eggs. Wolbachia in the mosquito's body can inhibit the replication of the Dengue virus or other viruses. Based on the Decree of the Minister of Health of the Republic of Indonesia Number 1341 concerning the Implementation of the Pilot Project for the Implementation of Wolbachia as a Dengue Management Innovation, the application of this technology was carried out in five cities, namely Semarang City, West Jakarta, Bandung City, Kupang City, and Bontang City. The effectiveness of Wolbachia itself has been proven and researched since 2011, when it was conducted in Yogyakarta. As a result, Wolbachia was proven to reduce dengue fever cases by up to 77% and reduce the proportion of hospital admissions by 86%. This method of spreading Wolbachia mosquitoes in several cities will reduce local transmission of infection in those areas. This reduction in local transmission of dengue infection occurs both in the rainy and dry seasons. Scientifically, the success of the Wolbachia method is apparent, but the controversy is due to confused information circulating, giving rise to concern among the public. Vector control using Wolbachia is an alternative disease control method that uses mosquito vectors and is quite effective. However, the application of Wolbachia in the community must be monitored continuously to determine its impact on humans, local mosquitoes, and the ecosystem.
Correlation of CD4+ levels and caspase-3 in condyloma acuminata with HIV reactive patients Nurfaiqoh, Elok; Mawardi, Prasetyadi; Dharmawan, Nugrohoaji; Julianto, Indah; Ellistasari, Endra Yustin
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21501

Abstract

Background: Human papillomavirus is an infection that causes malignancy because of persistency and modulation of apoptotic pathways, especially caspase-3. Factors that can increase persistency, recurrency, and malignancy of HPV infection include HIV infection with low CD4 levels. There is disagreement or deep molecular understanding of the induction and modulation of apoptosis in HIV-mediated CD4+ T cell depletion, especially in CA. However, it is necessary to see how CD4+ levels can influence caspase-3, so it may open up new avenues for supporting investigation to consider the presence of malignancy or therapeutic strategies regarding CD4+ can induce apoptosis.Purpose: This study aimed to determine whether there is a correlation between CD4+ levels and caspase-3 expression in condyloma acuminata with HIV reactive patients.Methods: This is an analytic observational study with a cross-sectional design. The research was conducted at Dr. Moewardi General Hospital from August to December 2023. Nineteen patients with condyloma acuminata and HIV reactive were included in this study with a consecutive sampling technique. The expression of caspase-3 was assessed using immunohistochemical staining, looking at the percentage of stained cell nuclei and cytoplasm and CD4+ levels with flow cytometry examination—data analysis using Pearson correlation.Results: Respondents in this study were primarily men, self-employed with heterosexual orientation and genito-genital-oral sexual intercourse. The statistical analysis showed no significant relationship (p: 0.300, r: -0.251) between CD4+ levels and caspase-3 expression.Conclusions: While not statistically significant, CD4+ level is reduced in correlation with increased caspase-3 expressions.
Antibacterial activity and perineal wound healing of swallow’s gel extracts Astiti, Gustiyana; Runjati, Runjati; Sudirman, Sudirman
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.15197

Abstract

Background: Swallow's nest has a glycol content of proteins, carbohydrates (25.62–27.26%), and proteins (62–63%); protein is an indispensable content for the healing process of perineal wounds, protein plays the main ingredient in cell formation, and repairs damaged tissues. In previous studies, swallow's nest extract against perineal wounds in mice obtained the results of accelerated healing on days 3 and 4. However, no studies have been conducted on human perineal injuries.Purpose: Knowing the effectiveness of the swallow's nest extract gel (Aerodramus Fuciphagus) 30% against wound healing and a decrease in the number of colonies of staphylococcus aureus bacteria in the perineal wounds of the postpartum mother.Methods: This experiment study has a post-test with a control group design. The sample comprised 34 postpartum maternal respondents divided into two groups randomly (intervention and control groups). The intervention group was given gel from swallow's nest extract while the control group carried out a dry clean treatment; both were treated to the wound. Perineal wound healing based on REEDA scores was analyzed using the Friedman test, while bacteria in perineal wounds were analyzed using the Man-Whitney test.Results: Based on the REEDA scale, the perineal wound healing rate in the intervention group was better, where healing had already occurred on day 5, compared to the control group that occurred on day 7 (p<0.0001). The number of bacteria in the perineal wounds of the intervention group was less, with an average of 0.06 CFU, compared to the control group's average control group's average of 1.11 CFU (p<0.05).Conclusion: Swallow's nest extract is influential and beneficial in healing perineal wounds in postpartum mothers and has antibacterial activity.

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