Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Majalah Obat Tradisional

TradMedJ
Website

Published by Universitas Gadjah Mada

ISSN : 14105918 EISSN : 24069086 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, Daerah Istimewa Yogyakarta, and we dedicate our journal to researches and development in traditional medicine. The journal receives papers on research laboratory, field research, and case studies of traditional medicine and its constituent, covering research topics including raw materials, cultivation, phytochemical, pharmacological effects and toxicology, formulation, and biotechnology.

Arjuna Subject : -

Articles 18 Documents

1 2

Search results for , issue "Vol 18, No 2 (2013)" : 18 Documents clear

IDENTITAS MAKROSKOPI, MIKROSKOPI, KIMIAWI, RIMPANG C. Mangga, C. Zedoaria, DAN K. Rotunda Sri Mulyani; Novia Dwi Nugraheni; Hendri Marinda Sari; A. Zulvita Anani Siswondo
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Zingiberaceae plants in Indonesia has been widely used as traditional medicine, such as Curcuma mangga, C. zedoaria, and Kaempferia rotunda. These three plants known as the temu putih. This study aims to determine the chemical content, macroscopic and microscopic characteristics, in order to obtain characteristics of each of these plants as an aid for identification. Macroscopic examination is conducted by observing the characteristics of the rhizome in both fresh and dried state, while the microscopic examination is done by observing the microscopic characteristics of the powder and fresh rhizome. Examination of the essensial oil is conducted to determine phytochemical compound by using GC-MS method. Result shown these three specimens, macroscopically have different taste and smell. Microscopically, these three specimens have different cork thickness, secrete cell colors, and different amylum size. As identity compound, for C. mangga, C. zedoaria, and K. rotunda oils are mirsena, germakrona and benzilbenzoat respectively.

PENGARUH TRAGAKAN SEBAGAI PENGIKAT TERHADAP SIFAT FISIK TABLET HISAP EKSTRAK JAHE (Zingiber officinalle Roxb.) Wintari Taurina; Yandi Syukri; Asih Triastuti
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Ginger (Zingiber Officinale Roxb.) is a traditional plants usually used to relieve pain, rheumatism, and neutralize poison. The aim of this study was to get the optimum concentration of tragacanth as a binding agent in ginger lozenges formulation. The components from ginger were extracted using percolation with ethanol 70% and then evaporated using rotary evaporator. Lozenges were made in three formulas ; formula 1 (5%), 2 (7,5%), 3 (10%) of tragacanth using wet granulation method. Granules and tablets were tested for its physical properties, and analyzed using Pearson correlation. The result showed that, all of three formulas were good, comply with a regulation of physical properties and soluble time in the mouth. Variation of tragacanth concentration affected physical properties of tablets. It showed that the greater concentration of tragacanth, the larger the hardness and the longer the soluble time of tablets. The formula (tragacanth 10% b/v) gave an optimum physical properties and soluble time of tablets, with weight variety deviation 0,98%, hardness 10,18 kg, friability 0.11% and soluble time 11.50 minutes. The three formulas were received by respondens with prerequirement of improving sweetness, repairing form and the color of tablets.

INTERAKSI SENYAWA AKTIF DARI Aegle marmelos CORREA SEBAGAI ANTI INFLAMASI DENGAN RESEPTOR COX-1 DAN COX-2 Dani Dwi Agistia; Hari Purnomo; Maulana Tegar; Agung Endro Nugroho
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

The compounds in Aegle marmelos have an activity as anti inflammation. The objective of this study is to evaluate six active compounds in Aegle marmelos Correa, (E,R)- Marmin, skimmianine, (S)-aegeline, aurapten, zeorin, and dustanin as anti inflammation to the COX-1 and COX-2 as target receptors. Method: Molecular docking was done with PLANTS. Ligand preparation used MarvinSketch, and protein preparation was done by using YASARA. The result was marmin, skimmianine, aegeline, aurapten, zeorin, and dustanin have interaction with Arg120, tyr 355, and Ile 523 in COX-1 and Ser353, Arg 513, and Ser 530 in COX-2. Based on the result of molecular docking, active compounds in Aegle marmelos Correa have potency as anti inflammation agent.

PENGARUH KADAR FENOLIK PADA DAUN TEH Camelia xinensis L. TERHADAP PREFERENSI EMPOASCA SP. (Homoptera : Cicadellidae) Saiful Saiful; Sudarsono Sudarsono
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Phenolic compounds are secondary metabolites found in all parts of the plants aree.g.:fruits, barks, roots, and leaves of plants serve as chemical defenses as repellent against insects and herbivorous detterent. On tea leaves, the results of research gallocatechin (a derivate of catechin) was functioning known as mechanism of resistance to Empoasca sp. (Homoptera: Cicadelliadae). The aim of this research was to know the total phenolic content of the young tea leaf (Camelia sinensis L.) and it was to found out the effect of the phenolic compounds of preference Empoasca sp. The results obtained that the clone of “Pasir Sarongge” (PS) had total phenol content (polyphenol average ± SD) 25,69 ± 0,1 higher than Kiara clone 18,47 ± 0,13. The higher the polyphenol in the young tea leaf bud could be act as Empoasca sp. Detterent.

FORMULASI MOUTHWASH MINYAK ATSIRI DAUN KEMANGI (Ocimum basilicum L.) SERTA UJI ANTIBAKTERI DAN ANTIBIOFILM TERHADAP BAKTERI Streptococcus mutans SECARA IN VITRO Ardiana Dewi Yosephine; Martha Purnami Wulanjati; Teuku Nanda Saifullah; Puji Astuti
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Basil leaves (Ocimum basilicum L.) contain essential oil that have been reported to have antibacterial activity. Based on this antibacterial activity, basil oil can be developed as mouthwash to prevent a dental plaque. This study aims to investigate the influence of tween 80 (as emulsifying agent) and glycerin (as stabilizer) on physical characteristics of the mouthwash, the ratio between tween 80 and glycerin for best stability, and in vitro antibacterial and antibiofilm activity of the mouthwash against Streptococcus mutans. Basil oil was extracted by water and steam distillation, then was formulated into mouthwash with a variation amount of tween 80 and glyserin. Antibacterial and antibiofilm activities weretested with micro dilution method. Result of study showed that tween 80 gives significant increase on viscosity and glycerin on specific mass when they were added at more than 2.5 mL in 50 mL mouthwash. From five formulas, formula with ratio of tween 80 and glycerin = 3.75 mL : 1.25 mL was found to be the best. Basil mouthwash showedin vitro antibacterial and antibiofilm activities against Streptococcus mutans. This product had MIC of 0.1 % v/v with 87,50 ± 3,33 % of bacterial inhibition. The MIC of biofilm formation and biofilm degradation was 0.1 % v/v and 0.2 % v/v, with % inhibition and degradation of 77,52 ± 0,82 % and 57,64 ± 6,09 %, respectively.

FORMULASI TABLET HISAP EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.) YANG MENGANDUNG FLAVONOID DENGAN KOMBINASI BAHAN PENGISI MANITOL-SUKROSA Yohanes Juliantoni; Mufrod Mufrod
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Flavonoid compounds found on the leaves of the guava are known to have an antibacterial activity. The aim of this study is to formulate an acceptable guava leaf extract preparations. Extract of guava leaves was formulated into several dosages of lozenges in combination with fillers manitol-sucrose. A Simple method of Lattice Design was used to know the influence of the combination physical properties of granule and lozenges and also predicting which formula is optimal. The extract was made by maceration of simplisia using ethanol 70%, thickened and then dried using the tool freeze dryer. The lozenges was created in 5 formula based on a combination of sucrose: manitol, F1 (0%: 100%); F2 (25% 75%); F3 (50%: 50%); F4 (75%: 25%); F5: 25% (75%) using a 5% aqueous gelatin as a binder. The dried granule then mixed with a lubricant and tested for the properties such as free flowing. The resulting lozenges were tested of its uniformity of weight, hardness tested tablets, fragility and responses to the taste. Simple lattice equation design and optimum formula predicted using Design software Expert version 8.0.5.2. Changes in the proportion of sucrose-manitol combinations affect the physical properties of granule and lozenges. Based on an analysis using the Design software Expert version 8.0.5.2, the optimal formula is given by a combination of manitol-sucrose 82,28%: 17.72%.

PENETAPAN KADAR ALKALOID DARI EKSTRAK ETANOLIK BUNGA KEMBANG SEPATU (Hibiscus rosa-sinensis L.) Mimiek Murrukmihadi; Subagus Wahyuono; Marchaban Marchaban; Sudibyo Martono
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Kembang sepatu flower (Hibiscus rosa-sinensis L.) was fractionally used as expectorant. Based on Bioassay Guided fractionation, an active fraction was separated, and the fraction was identified is Alkaloid was the major compound based on TLC analysis. Viscosity value measured by viscometer was used as a Bioassay model of expectorant activity in vitro and asetyl cysteine was used as positive control. Alkaloid content determination of the ethanolic extract was measured by TLC-Densitometric compared with standard curve of isolated alkaloid as the selected marker (Y=12.1360X+2901.4474). The alkaloid content in the ethanolic extract was determined as 2.35 ± 0.67 %.

AKTIVITAS ANTIBAKTERI MINYAK ATSIRI KULIT JERUK PONTIANAK TERHADAP Staphylococcus aureus dan Escherichia coli Rafika Sari; F. Nour Aulia Mustari; Sri Wahdaningsih
Majalah Obat Tradisional Vol 18, No 2 (2013)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

The infectious diseases can be caused by the pathogenic bacteria among Staphylococcus aureus and Escherichia coli. One of the plants that can be used as antibacterial is essential oils from Pontianak orange peels (Citrus nobilis Lour. var. microcarpa). This research aims to determine the antibacterial activity essential oils Pontianak orange peels againts the pathogenic bacteria by disc diffusion method. This research carried out by using the experimental Completely Randomized Design (CRD) Factorial and outcome data were analyzed using the program CoStat Two Way ANOVA method and continued by using LSD (Least Significant Different). The results showed that the essential oils from Pontianak orange peels contain flavonoids, saponins, and triterpenoids. The essential oils from Pontianak orange peels have antibacterial activity againts Escherichia coli and Staphylococcus aureus, where the average zone of inhibition obtained from the concentrations from 0,5; 1,5; and 2,5 mg/mL respectively are 15; 16; and 19 mm and 16,33; 18; and 21 mm. The concentration that gives the biggest inhibition zone is 2,5 mg/mL.

Page 2 of 2 | Total Record : 18

1 2

Filter by Year

2013 2013

Filter By Issues

All Issue Vol 30, No 3 (2025) Vol 30, No 2 (2025) Vol 30, No 1 (2025) Vol 29, No 3 (2024) Vol 29, No 2 (2024) Vol 29, No 1 (2024) Vol 28, No 3 (2023) Vol 28, No 2 (2023) Vol 28, No 1 (2023) Vol 27, No 3 (2022) Vol 27, No 2 (2022) Vol 27, No 1 (2022) Vol 26, No 3 (2021) Vol 26, No 2 (2021) Vol 26, No 1 (2021) Vol 25, No 3 (2020) Vol 25, No 2 (2020) Vol 25, No 1 (2020) Vol 24, No 3 (2019) Vol 24, No 2 (2019) Vol 24, No 1 (2019) Vol 23, No 3 (2018) Vol 23, No 2 (2018) Vol 23, No 1 (2018) Vol 22, No 3 (2017) Vol 22, No 2 (2017) Vol 22, No 1 (2017) Vol 21, No 3 (2016) Vol 21, No 2 (2016) Vol 21, No 1 (2016) Vol 20, No 3 (2015) Vol 20, No 3 (2015) Vol 20, No 2 (2015) Vol 20, No 2 (2015) Vol 20, No 1 (2015) Vol 20, No 1 (2015) Vol 19, No 3 (2014) Vol 19, No 3 (2014) Vol 19, No 2 (2014) Vol 19, No 2 (2014) Vol 19, No 1 (2014) Vol 19, No 1 (2014) Vol 18, No 3 (2013) Vol 18, No 3 (2013) Vol 18, No 2 (2013) Vol 18, No 2 (2013) Vol 18, No 1 (2013) Vol 18, No 1 (2013) Vol 17, No 3 (2012) Vol 17, No 3 (2012) Vol 17, No 2 (2012) Vol 17, No 2 (2012) Vol 17, No 1 (2012) Vol 17, No 1 (2012) Vol 16, No 3 (2011) Vol 16, No 3 (2011) Vol 16, No 2 (2011) Vol 16, No 2 (2011) Vol 16, No 1 (2011) Vol 16, No 1 (2011) Vol 15, No 3 (2010) Vol 15, No 3 (2010) Vol 15, No 2 (2010) Vol 15, No 2 (2010) Vol 15, No 1 (2010) Vol 15, No 1 (2010) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Pudyastuti Kusumaningrum

Contact Email
mot.farmasi@ugm.ac.idm

Phone
-

Journal Mail Official
mot.farmasi@ugm.ac.id

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Pudyastuti Kusumaningrum

Contact Email mot.farmasi@ugm.ac.idm

Phone -

Journal Mail Official mot.farmasi@ugm.ac.id

Editorial Address -

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Pudyastuti Kusumaningrum

Contact Email
mot.farmasi@ugm.ac.idm

Phone
-

Journal Mail Official
mot.farmasi@ugm.ac.id

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA