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Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan

kedokteran
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Published by Universitas Jambi

ISSN : 2339269X EISSN : 25806874 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Jambi Medical Journal is a Journal for Medical And Health Issues, in Scope: Medical Education, Farmakology, Mikrobiology, PUblic Health, Clinical Patology, Medical Nutrition, Clinical Medicine, Pediatric, Immunology, Patology Anatomi, Orthopedy, Obstetri and Gynekology, Internal Medicine, Endocrine and Metabolic, Genetics & Molecular Biology.

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Articles 366 Documents

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Hubungan Pola Kuman Saluran Cerna Anak Autis terhadap Tumbuh Kembang di Kota Jambi Putra, Irawan Anasta; Syauqy, Ahmad
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Autism is developmental disorder that appears in children before the age of three and the cause is not known yet. Characteristics of autism are deficits in communication, social interaction, behavior and indigestion. Therapy for autism is not only behavioural therapy but also gluten free-casein free diet. The aim of this study is to describe the characteristics of the growth and development of children with autism at the age of 2-6 years and to see the possibility of the relationship between the pattern of microbe in tractus gastrointestinal and the growth level in children. Methods: Descriptive cross-sectional study, included 49 children with autism at the age of 2-6 years and their parents in special schools of Prof. Dr. Sri Soedewi Masjchun Sofwan, SH and three foundation of children with special needs in Jambi city. Result: 89,8% respondents aged 4-6 years; 87,9% dominated by boys; 87,8% autism is more common in pregnant women aged 21-35 years; 61,2% mothers had never experienced TORCH infection; 93,9% gave birth at >37-42 weeks gestation; 85,7% respondents had never experienced signs of severe breathing at birth; 89,8% had never experienced signs of meningitis or seizures; 33 parents have known about GFCF diet, but only 28 parents who apply the diet. From 28 parents; 21 replace cow’s milk to soy milk, 12 regular and discipline on the diet and 20 felts the positive effects of the diets. 49 respondents: 69,4% has normal nutritional status and 98% has suspect in development disorders. There are the relationships in statistic between the growth level of autism child with microbe Proteus mirabilis. Conclusion: The majority of children with autism at the age of 2-6 years in Jambi City have normal growth, yet fall into the category of suspect in developmental disorders. Proteus mirabilis is a microbe which has the relationships statistically with the growth level of autism children. Keywords: Autism, growth, development, pattern of microbe

Korelasi Ekspresi VEGF dan Densitas Mikrovesel Dengan Respons Radioterapi Adenokarsinoma Serviks Wibisono, Fennisia; Suryanti, Sri; Hernowo, Bethy S
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Most of cervical carcinoma patients, including cervical adenocarcinoma comes at an advanced stage and thus radiotherapy is one of the modality treatment. The success of radiotherapy depends on several prognostic factors such as the performance, staging, histopathology of tumor, presence of organ dysfunction and cellular biology marker such as VEGF. Activation singaling pathway Vascular Endothelial Growth Factor (VEGF) can induce radioresistance on cervical adenocarcinoma. Activation angiogenesis mediated by VEGF can be counted from microvessel density (MVD). Counting MVD use imunohistochemical CD34 on endothelial cells form capiller of blood vessel in peritumoral. The aim of this study was to determine correlation between immunohistochemistry VEGF dan MVD with neoadjuvant radiotherapy response cervical adenocarcinoma. Methods: This study was an observational study, cross-sectional and correlational analysis. Samples was collected by total sampling with amount 32 samples block parafin from Departement Anatomical Pathology General Hospital Dr. Hasan Sadikin Bandung and treated with complete neoadjuvant radiotherapy from Januari 2007 until December 2013. Immunohistochemical examination of VEGF and CD34 for counting MVD was done on all sample block parafin. Result: There was a strong correlation between microvessel density (MVD) with neoadjuvant radiotherapy response in cervical adenocarcinoma (p = 0.000). In this study MVD above 30 correlate with poor neoadjuvant radiotherapy response in cervical adenocarcinoma. Conclusion: Examination MVD recommended for cervical adenocarcinoma patient before radiation treatment. Keyword : Cervical Adenocarcinoma, CD34, Neoadjuvant Radiotherapy, VEGF

Pengaruh Terapi Antituberkulosis Terhadap Pertumbuhan Penderita Tuberkulosis Anak di Kota Jambi Rahman, Ave Olivia; Ayu, Esa Indah; ., Miftahurrahmah
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Tuberculosis (TB) is still a major health problem in the world. Indonesia is in the top fifth contributing to the highest number of TB cases in the world. Subdit TB Depkes RI 2000-2010 reported that Jambi is one of the province with high proportion of pediatric TB, 5,2%. Tuberculosis can affect the children’s growth. Combination of antituberculosis drugs are used in the therapy of tuberculosis. Some studies show that the antituberculosis drugs cause side effects. Methods: This is an observational research with cohort prospective design. Subjects are patients who diagnosed as pediatric TB in RSUD Raden Mattaher, Puskesmas Putri Ayu, Puskesmas Simpang IV Sipin and PPTI Jambi. Subjects have given informed consent. The recruitment of subject from July until September 2014 and followed until two month therapy. The primary data from interview and weight measurement, secondary data from patients’ medical records. Results: Total subjects are 24 patients. The 87,5% subjects diagnosed as TB pulmonary and 12,5% subjects diagnosed as TB extrapulmonary (meningitis TB, spondylitis TB and scrofuloderma). About 54,2% subjects are above 4 years old. The location of patients’ adresses are 20,8% from Kecamatan Jambi Timur subdistrict, followed respectively from Telanai, Kota baru, Pelayangan, Jelutung and Danau Teluk. The 79,2 % subjects have close contact with positive TB adult patients. About 8,3% subjects experience loss of appetite, 4,1 % experience naussea during therapy with antitubercular drugs. Based on weight/age criteria, about 91,7 % subjects are categorized malnutrition and 8,3 % are well nutrition before therapy. There are different significantly increasement of body weight before, after 1 month and 2 month of therapy (p<0,05). Conclusion: There are significantly increasement of body weight before, after 1 month and 2 month of therapy (p<0,05). Keywords: Pediatric TB, growth weight, side effects

Perbandingan Efektivitas Pembelajaran Clinical Skill Lab (CSL) dengan Menggunakan Video Ajar Keterampilan Klinik Neurologi terhadap Demonstrasi oleh Instruktur Aryanty, Nindya; Puspasari, Anggelia; Purwakanthi, Anati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background : Medical Faculty University of Jambi has been implemented clinical skills lab (CSL) as one of learning methode. Limited time for encounter a learning topic which discuss just once in learning session may effect student ability to perform clinical skill of learning topic. There are many research represent advantages of learning video as effective learning media to gained student memory for a learning topic. The aim of this research was to compared effectiveness student clinical skill neurology examination ability using learning video with direct instructor teaching perform. Student ability to perform clinical skill assess using checklist procedure. Methode: This research was true experimental with posttest only control design. This research held at Medical Faculty University of Jambi in June until August 2014. Population of this research was all student in first years. Sample randomly selected and grouped as experiment (69 students) and control (68 students). Experiment group gave clinical skill neurology examination video, control group gave direct instructor teaching perform. Result: Evaluation based on checklist represent of experiment group had median value 78,13 (range 50,00) and control group had median value 74,25 (range 75,76). Mann U-Whitney test find the p- value for compared two group was 0,657 (p>0,05), there was no significant statistically between experiment and control group. Conclusion : In conclusion student who did not follow clinical skill learning session can learned from video, video may consider as learning media to over come limitation human resources and time of lecture in medical faculty. Kata Kunci : Clinical Skill Lab, Learning video, Neurology clinical skill

Perbandingan Imunoekspresi p53 dan Caspase-3 Pada Mola Hidatidosa Parsial, Mola Hidatidosa Komplit, dan Koriokarsinoma Reis, Odilia Dos; Agustina, Hasrayati; Hassan, Abdul Hadi; Hernowo, Bethy S
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Partial hydatidiform mole, complete hydatidiform mole and choriocarcinoma are gestational trophoblastic diseases which have high incidence in Indonesia. Most complete hydatidiform mole can transform into choriocarcinoma , but pathogenesis of the transformation is remain unknown. Apoptosis plays an important role in the pathogenesis of human malignancy. p53 and caspase - 3 play a role in apotosis . The aim of this study is to evaluate the p53 and caspase-3 immunoexpression in partial hydatidiform mole, complete hydatidiform mole and choriocarcinoma Methods: This is an observational analytic cross sectional study, conducted on 30 cases of gestational trophoblastic diseases consisted of 10 cases of partial hydatidiform mole, 10 cases of complete hydatidiform mole and 10 cases of choriocarcinoma. Immunohistochemical examination of p53 and Caspase-3 were performed on all cases. Result : The result showed significant difference between the p53 immunoexpression in partial hydatidiform mole and choriocarcinoma (p = 0.002), there was no significant p53 immunoexpression difference between complete hydatidiform mole and choriocarcinoma (p = 0.121), there was no caspase-3 immunoexpression difference between partial hydatidiform mole and choriocarcinoma (p = 0.160) and there was no caspase-3 immunoexpression difference between complete hydatidiform mole and choriocarcinoma (p = 0.361). p53 Immunoexpresion was higher in the case of complete hydatidiform mole and choriocarcinoma but tend to be lower in partial hydatidiform mole. Conclusion : In conclusion, p53 may play a role in the pathogenesis of complete hydatidiform mole and choriocarcinoma, but has a lesser role in the pathogenesis of partial hydatidiform mole. Caspase-3 might not play a role in the pathogenesis of hydatidiform mole transformation into choriocarcinoma. Keywords: complete hydatidiform mole, partial hydatidiform mole, choriocarcinoma, p53, caspase-3.

Perbandingan Kemampuan Antifungi Minyak Atsiri Cengkeh (Eugenia aromatica) dan Ketoconazole 2% terhadap Candida albicans secara In Vitro Fitri, Amelia Dwi; ., Emiyati; ., Aparaminta
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v2i2.2714

ABSTRACT Background: Candida albicans is a normal flora in some mucous membranes in the body that are opportunistic, so that in certain circumstances may be pathogenic. Currently the use of traditional medicine as a tendency of increasing antifungal, one of which is a plant that contains essential oils. One of the plants that contain essential oils and widely used in the community are clove (Eugenia aromatica). This study aims to prove the existence of antifungal activity of the essential oil of clove (Eugenia aromatica) against Candida albicans and compared with antifungal activity of ketoconazole 2%. This study was conducted to determine the ability of clove essential oil against the proliferation of the fungus Candida albicans and compare it with the antifungal activity of ketoconazole 2%. Methods: This study was a laboratory experimental study using in vitro testing. The method used is the dilution liquid to assess the Minimal Inhibitory concentration (MIC) and Minimum Levels Kill Concentration (MKL) essential oil of cloves to the proliferation of the fungus Candida albicans and compare it with the antifungal activity of ketoconazole 2%. The means used to make several serial dilutions of test material with a concentration of 40%, 20%, 10%, 5%, 2.5%, 1.25%, and 0.625%. This study was performed three times of testing. Ketoconazole used in this study is ketoconazole 2% Results: Of the three testing times obtained MIC clove essential oils against the proliferation of the fungus Candida albicans is 1.25%. While MKL clove essential oils against the proliferation of the fungus Candida albicans is 1.25%. MIC and MKL ketoconazole of three tests on the proliferation of the fungus Candida albicans is 2% Conclusions: The ability of clove essential oil antifungal concentration of 1.25% in inhibiting the fungus Candida albicans is proportional to the ability of antifungal ketoconazole 2% in inhibiting the fungus Candida albicans. While the ability of clove essential oil concentration of 1.25% in killing the fungus Candida albicans is proportional to the ability of antifungal ketoconazole 2% in inhibiting the fungus Candida albicans Keywords: Essential oil of clove (Eugenia aromatica) - Candida albicans - ketoconazole 2% - MIC-MKL.

Ekspresi Enzim Metabolisme Vitamin D Pada Sistem Reproduksi Pria Syauqy, Ahmad
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 3 No. 1 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Nowadays moleculer biology is developed. The scientist try to make a mapping of proteins that exist in male reproduction. It is supposed to know fertility factor for advance in moleculer way so that it can be used as the information to solve the infertility cases in male. One of the protein that is identificated in male reproduction system is enzyms that used in metabolism vitamin d. Those enzyms is known can be found in organ that is used in metabolism vitamin D, they are liver and kidney. On liver, enzym 25-d- hidroksilade exist and it is used to activate vitamin D. Meanwhile, on kidney enzym 24-hydroksilase exist, it is used to inactivate vitamin D. All of the enzyms are used in activate and inactivate vitamin D are also use in male reproduction tract and so do sprem with variation level of expression. It show that vitamin D is also take an important role in male fertility. The use of vitaminD specificly is not much revealed yet in male reproduction system. The use of vitaminD that has been revealed was sperm capacity, sperm motility and to increase the resistancy of sperm. Keyword : enzym,vitamin D,male reproduction

The Influence Cognitive Behavioral Therapy To Resilience in Adolescents at Risk Ayu, Nyimas Natasha; Saputra, Nofrans Eka
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 3 No. 1 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Introduction : Adolescents at risk is a high-risk group involved in the problems associated with behavioral health problems such as smoking, drug abuse, drinking, bullying and sexual behavior. Cognitive behavioral therapy as an active therapy is one of the alternative ways to improve resilience in adolescents at risk. Method : This study aims to find a deskriptions of risk behavior in adolescents and to determine the difference resiliency capabilities at risk pre and post the cognitive behavioral therapy. Collecting data is using risk behavior questionaire and resilience scale. Population with characteristic 13 – 19 years old adolescents at risk.. Samples were taken by using purposive random sampling technique. Experimental design of this study is true experimental pretest-postest control group design. Paired sample T test is used to analize the data. Result : This study shows that adolescents at risk have been doing bullying, smoking, drug abuse, and active sexual behavior. This study also shows that there is a significant difference of resilience ability pre and post the cognitive behavioral therapy for the experimental group, with p=0,009. While the control group showed no differences in adolescent resilience ability pre or post cognitive behavioral therapy with p=0,976 Conclusions And Recommendations : Adolescents who have risky behaviors can improve their resiliensy by using cognitive behavioral therapy. School is expected to be able to cooperate with stakeholders in preparing sustainable activities to reduce the risk behaviour in adolescents. Keywords: Adolescents at risk, resiliency, cognitive behavioral therapy.

Hubungan Durasi Pemberian Asi Dengan Status Gizi Anak Usia 0-24 Bulan di Puskesmas Simpang IV Sipin Kota Jambi Tahun 2015 Amri, Nurul Khairiyah; Putra, Irawan Anasta; Karolina, Maria Estela
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 3 No. 1 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v3i1.2717

ABSTRACT Background : The connection between breastfeeding duration starts on 0 Until 24 month and child's nutritional stat still bring some controversy. Positive and negative correlation can be seen ss result. This study purpose is to support the giving of exclusive breastfeeding for 2 whole years ( start from one hour after delivery, exclusive breastfeeding for 6 month, no bottle feeding, and 2 years or more of breastfeeding) in Jambi and the correlation with 0 – 24 month child’s nutritional state. Based on Jambi’s Health Departement data in 2013, there was counted 1545 exclusive breastfeeding on 0 – 6 months children within 20 local Primary health care unit in Jambi. On Simpang IV Sipin area, there was 118 babies who got exclusive breastfeeding on 2013. Objective : To determine relationship between duration of breastfeeding and nutritional status of children aged 0 – 24 months in Simpang IV Sipin Health Center Jambi in 2015. Methods : This Study used analytical research’s method with crosssectional approach held at Simpang IV Sipin Primary health care unit on 2015. This research used consecutive sampling to Primary health care unit the samples and got 73 children to be followed. This Study data been analyzed by using one- way Anova test. Results : Based on data, we can conclude that there is correlation between breastfeeding duration with nutritional state ( p value 0,037), child with normal nutritional state ( 29 children ) have breastfeeding duration for 8,9 month in average. Child with thin nutritional state have breastfeeding duration got 5,3 months in average, and child with fat nutritional state have breastfeeding duration got 10,2 month ib average. Conclusion: There is relationship between exclusive breastfeeding with nutritional status at age 0 – 24 months in Simpang IV Sipin Primary health care unit Jambi in 2015. Keywords : Exclusive breastfeeding, nutritional status

Penerapan Multi-Source Feedback (MSF) Dalam Penilaian Perilaku Profesional Mahasiswa Kedokteran Fitri, Amelia Dwi
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 3 No. 1 (2015): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRAK Latar belakang : Profesionalisme merupakan salah satu factor penting yang harus dimiliki oleh seorang dokter. Organisasi profesi di Amerika Serikat seperti the American Board of Internal Medicine (ABIM) telah menetapkan beberapa aspek yang termasuk dalam profesionalisme seperti altruisme, empati, saling menghormati, integritas, etika dan moral, tanggung jawab, dan komiten untuk belajar sepanjang hayat. General Medical Council (GMC) di Inggris menetapkan tujuh aspek profesionalisme yang harus dimiliki oleh dokter, Di Indonesia, Konsil Kedokteran Indonesia (KKI) telah menetapkan bahwa salah satu area kompetensi dokter adalah aspek Etika, Moral, Medikolegal dan Profesionalisme serta Keselamatan Pasien. Oleh karenaitu, dalam Kurikulum Berbasis Kompetensi (KBK) yang saat ini diterapkan oleh sebagian besar Fakultas Kedokteran di Indonesia, aspek profesionalisme harus menjadi perhatian baik dalam proses pembelajaran maupun dalam system penilaian. Metode penilaian terhadap perilaku professional sebaiknya tidak hanya dilakukan di akhir proses pembelajaran saja namun harus berkelanjutan dalam seluruh proses pembelajaran yang dijalani mahasiswa kedokteran. Tujuan : pemaparan secara komprehensif mengenai Multi-Source Feedback (MSF) atau 3600 evaluation sebagai metode penilaian yang dapat diterapkan untuk menilai aspek profesionalisme dalam pendidikan dokter. Metode :studi literature mengenai MSF meliputi tujuan penggunaan, prosedur, kekuatan, kelemahan dan keterbatasan, validitas dan reliabilitas serta kredibilitas penilai Kesimpulan : MSF merupakan salah satu metode penilaian yang valid dan reliable dalam menilai perilaku professional mahasiswa kedokteran, namun dalam penerapannya ada banyak factor yang harus dipertimbangkan agar tujuan pembelajaran yang diinginkan dapat tercapai.

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