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Dentino: Jurnal Kedokteran Gigi
Published by Universitas Lambung Mangkurat
ISSN : 23375310     EISSN : 25274937     DOI : 10.20527
Core Subject : Health,
Dentistry
Dentino [P-ISSN 2337-5310 | E-ISSN 2527-4937] is the journal contains research articles and review of the literature on dentistry which is managed by the Faculty of Dentistry, Lambung Mangkurat University. Dentino published twice a year, every March and September.
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Articles 20 Documents
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Search results for , issue "vol 11, no 2 (2026)" : 20 Documents clear
Effect of Moringa Oleifera Leaf Extract Gel On Fibroblast In Diabetic Traumatic Ulcer Raziv Ganesha; I Gusti Ngurah Putra Dermawan; Intan Kemala Dewi; Ni Putu Wulan Cahyani
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26501

Abstract

Introduction: Diabetes mellitus (DM) is a metabolic disease that impairs wound healing, including traumatic ulcers in the oral mucosa, by suppressing fibroblast proliferation. Purpose: This study aims to evaluate the effect of Moringa oleifera leaf extract gel on the number of fibroblasts during the healing process of traumatic ulcers in diabetic Wistar rats. Methods: This experimental study used a post-test only control group design. A total of 8 groups (n=4 rats/group) were observed across four time intervals (days 3, 5, 7, and 9). The rats received applications of either 15% Moringa oleifera leaf extract gel or 3% Na-CMC gel (control) three times daily. Labial mucosal tissues were harvested, and fibroblast counts were evaluated using Hematoxylin and Eosin staining. Data were analyzed using the Mann-Whitney U test. Results: The mean fibroblast ratios between the 15% Moringa gel and 3% Na-CMC gel groups were: day 3 (3.1 vs. 3.0), day 5 (4.3 vs. 3.85), day 7 (3.75 vs. 5.3), and day 9 (7.4 vs. 6.05). Statistical analysis revealed no significant differences on days 3, 5, and 9, whereas a statistically significant difference was observed on day 7. Antioxidant and anti-inflammatory compounds in Moringa leaves—such as flavonoids, phenolics, and vitamin C—reduce free radicals and inhibit pro-inflammatory cytokines, enhancing fibroblast survival. Additionally, Moringa oleifera promotes TGF-β1 and VEGF expression, stimulating fibroblast proliferation and angiogenesis..Conclusion: Application of Moringa oleifera on days 3, 5 and 9 resulted in higher fibroblast counts than in the control group, except on day 7.
Musa Paradisiaca Var. Sapientum Stem Sap Phytochemicals as Candidate Cox-2 Inhibitors: An In Silico Study for Recurrent Aphthous Stomatitis Treatment Tiara Nada Assadat; Silvia Anitasari; Verry Asfirizal
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26858

Abstract

Background: Recurrent aphthous stomatitis (RAS) is a common ulcerative disorder of the oral mucosa in which cyclooxygenase-2 (COX-2)-derived prostaglandin E2 contributes to pain and inflammation. Stem sap of Musa paradisiaca var. Sapientum (Ambonese banana) is used ethnomedicinally for oral ulcers, but the constituents responsible for its anti-inflammatory effect are unidentified. Objective: To screen phytochemicals previously reported from M. paradisiaca stem sap for predicted binding to human COX-2 and to characterise their predicted pharmacokinetic (ADMET) profiles, in order to prioritise candidates for experimental testing. Methods: Nine phytochemicals compiled from published phytochemical reports, together with celecoxib and the co-crystallised ligand rofecoxib, were docked into human COX-2 (PDB ID 5KIR). The protocol was validated by redocking rofecoxib. ADME-T descriptors were predicted with SwissADME and ADMETlab 3.0. Result: The docking protocol was successfully validated (RMSD = 0.992 Å). The five best-scoring compounds were catechin (docking score = −8.76 kcal/mol; predicted Ki = 376.01 nM), gallocatechin (−8.59; 504.97 nM), quercetin-3-O-glucoside (−8.43; 658.19 nM), quercetin (−8.38; 721.52 nM) and leucocyanidin (−8.37; 734.98 nM). Each formed hydrogen bonds with Tyr385, Ser530 or Gln192 and hydrophobic contacts with Leu352 and Val523. All five were predicted to have low Caco-2 permeability and low human intestinal absorption, and four carried a high predicted skin-sensitisation probability. Conclusion: Catechin and gallocatechin were the best-scoring candidate COX-2 inhibitors. Their binding affinity and favorable topical pharmacokinetics support their potential as non-steroidal anti-inflammatory agents for RAS. Further evaluation of COX-1/COX-2 selectivity, in vitro, and in vivo experimental validation are required to confirm these findings.
Development of A Digital Forensic Odontology Workflow Integrating Smartphone-Based 3D Dental Documentation and Telegram-Based Dental Records Basma Rosandi Prakosa; Fery Setiawan; Anand Marya; Dinda Khairunisa Rosandi; Prima Fiducia Andini; Fathony Teguh Irawan; Tio Dary; Natasha Henita Pidang; Shintya Rizki Ayu Agitha
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26757

Abstract

Background: The availability of complete and accessible antemortem dental records is essential for forensic odontology identification. Conventional dental records have limitations in data storage, retrieval, and documentation standardization. Integration of three-dimensional (3D) dental documentation and electronic dental records may improve forensic dental data management. Purpose: This study aimed to develop and evaluate an integrated digital forensic odontology workflow combining Boxphone-assisted smartphone image acquisition, Blender-based 3D dental model construction, and Telegram-based electronic dental records for individual identification simulation. Methods: This research employed a research and development design followed by system evaluation. Dimensional agreement was evaluated using 44 dental casts, while electronic dental record workflow efficiency was evaluated using 43 simulated patient datasets across manual, Telegram-based, and web-based systems. Parameters included mesiodistal first-molar measurement, data-entry time, and data-retrieval time. Results: The overall mean mesiodistal measurement was 10.83 mm for the reference dental casts and 10.84 mm for the reconstructed 3D models; the difference between the two overall means was 0.01 mm. The Telegram-based system showed a mean data-entry time of 149.41 seconds, compared with 225.27 seconds for the manual record and 259.00 seconds for the web-based system. Mean retrieval time was 6.72 seconds for the Telegram-based system, 21.72 seconds for the manual record, and 8.00 seconds for the web-based system. Conclusion: The integrated workflow showed close group-level dimensional agreement between reference and reconstructed measurements and shorter descriptive task-completion times for the Telegram-based record system in this controlled evaluation
Mechanical Properties of Glass Ionomer Cement Modified with Natural Nanosilica From Slopeng Beach Sand: A Comparative Study Fani Pangabdian; Sinta Puspita; Dimas Nugroho; Agung Satria Wardhana; Niesha Amelia Salzabila
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26280

Abstract

Background: Glass Ionomer Cement (GIC) is a restorative material capable of releasing fluoride to protect teeth against the activity of cariogenic bacteria. However, the clinical use of GIC in restorations is limited by its relatively low mechanical strength. The incorporation of nano-silica has been investigated as a potential modification to improve the mechanical properties of GIC, including compressive strength, flexural strength, and microhardness. Purpose: This study aims to compare the mechanical strength of conventional GIC combined with synthetic nano-silica, and GIC combined with natural nano-silica from Slopeng Beach sand.MethodsThe study consisted of three material groups, each containing 24 specimens, resulting in a total of 72 specimens. Included 24 conventional GIC (K), 24 GIC modified with natural nanosilica from Slopeng Beach sand (P1), and 24 GIC modified with synthetic nanosilica (P2).Results: Compressive Strength Test: K 37.09 ± 16.41 N/mm2, P1 63.59 ± 12.78 N/mm2, and P2 41.85 ± 18.38 N/mm2; Flexural Strength Test: K 23.67 ± 12.88 N/mm2, P1 34.15 ± 10.42 N/mm2, and P2 27.26 ± 11.03 N/mm2; Microhardness Test: K 357.25 ± 15.21 HV, P1 415.46 ± 14.42 HV, and P2 389.26 ± 16.34 HV. Conclusion: GIC modified with natural nano-silica from Slopeng Beach sand exhibited higher compressive strength, flexural strength, and microhardness than GIC modified with synthetic nano-silica. 
A Study On The Effectiveness of Goji Berry Extract (Lycium Barbarum L.) In Increasing Collagen Fiber Density Following Tooth Extraction In Wistar Rats (Rattus Norvegicus) Shieny Lokanata; Dian Soraya Tanjung; Wulan Sahara Bengi; Mohammad Revaldy Sabran
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.25906

Abstract

Background: Tooth extraction initiates wound healing through inflammatory, proliferative, and remodelling phases, with collagen density serving as an important indicator of healing quality. Goji berry (Lycium barbarum L.) contains bioactive compounds, including polysaccharides, flavonoids, alkaloids, saponins, and tannins, which may promote fibroblast proliferation and collagen synthesis, supporting its potential to enhance post-extraction socket healing. Purpose: To evaluate the effectiveness of Goji berry extract gel at concentrations of 15%, 30%, and 55% on collagen fiber density in Wistar rat sockets subsequent to dental extraction. Methods: This research was an in vivo laboratory experimental study, single blind, utilizing a post-test only control group design. Thirty male Wistar rats were separated into five groups: negative control, positive control (Povidone Iodine), and Goji berry extract gel at concentrations of 15%, 30%, and 55%. Gel was applied topically twice daily for 14 days. Tissue samples were collected on days 3, 5, 7, and 14 for histopathological examination using an inverted phase contrast microscope at 400x magnification. Data were analyzed using One-Way ANOVA and Post-Hoc Duncan test. Results: Goji berry gel groups showed higher collagen density compared to both control groups across all observation days. Significant differences were found on days 5, 7, and 14 (p<0.05), with the 30% and 55% groups showing the highest collagen density values of 643.82 µm and 699.91 µm on day 14, respectively. Conclusion: Goji berry extract gel significantly increases collagen fiber density in Wistar rat sockets after tooth extraction, with 55% as the optimal concentration.
ANALYSIS OF CHILDREN'S BEHAVIOR AND DENTAL CARIES IN BANJARMASIN CITY'S URBAN AREA Riky Hamdani; Aulia Azizah; Raden Harry Dharmawan Setyawardhana; Isnur Hatta
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.27837

Abstract

Background: The elevated prevalence of pediatric dental caries is closely linked to oral health-related behaviors, including high dietary sugar intake, inadequate oral hygiene practices, and insufficient fluoride exposure. Purpose: This study aimed to identify the behavioral determinants associated with dental caries occurrence among elementary school children in the urban area of Banjarmasin City. Methods:  A cross-sectional study was conducted among 375 children aged 10–12 years in Banjarmasin City, selected via a multistage random sampling technique. Oral health behaviors were assessed using structured questionnaires, while caries experience was clinically evaluated using the Decayed, Missing, and Filled Teeth (DMFT) index. Non-parametric analyses, specifically the Mann–Whitney U test, were utilized to assess differences in mean DMFT scores across gender, parental income status, and sugary food consumption frequency. The Kruskal–Wallis test was performed to compare mean DMFT scores across age groups, toothbrushing frequency, toothbrushing timing/duration, and frequency of dental visits. Results: The statistical analysis revealed no significant differences in the mean DMFT scores across the evaluated variables (p>0.05), except for the variable frequency of tooth brushing (p=0.045) and tooth brushing time (p=0.000). Conclusion: Cases of tooth decay in children in urban areas of Banjarmasin city are still quite high, so intervention is needed, especially in improving good and correct tooth brushing behavior. Keywords: Behavior; Children; Dental caries
Oral Health Knowledge Change After Instagram Digital Posters Sunnati Sunnati; Zulfan M Alibasyah; Dewi Saputri; Nuzulul Izmi; Naira Nisa
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.27719

Abstract

Background: Oral health knowledge supports preventive oral health practices, and Instagram may provide an accessible channel for repeated health education. Purpose: This study aimed to describe changes in oral health knowledge before and after exposure to digital posters delivered through Instagram. Methods: A pre-experimental one-group pre-test and post-test study was conducted online through the Instagram account @nairansc in April–May 2026. The population comprised 1,422 followers; 323 eligible participants were included through simple random sampling. Knowledge was measured using a 15-item questionnaire. Four digital posters addressed toothbrushing, tongue cleaning, interdental cleaning, and factors associated with dental damage. Each poster was published three times in rotation during a 19-day intervention period, followed by one week of reposting. Pre-test and post-test scores were compared using a paired analysis. N-Gain was described by sex, education, and age. Results: The proportion of participants with good knowledge increased from 79.3% (256/323) to 97.2% (314/323). The mean score increased from 12.87 ± 1.71 to 14.56 ± 0.98, an absolute increase of 1.69 points (p < 0.001). N-Gain was high for both males (0.73) and females (0.76), and for junior high school (0.71), senior high school (0.72), and university education (0.79). By age, N-Gain was 0.75, 0.63, 0.70, and 0.86 for the 18–22, 23–27, 28–32, and ≥33-year groups, respectively.Conclusion: Oral health knowledge was higher after exposure to the Instagram-based digital posters in this study population. Because the design lacked a control group, the observed change cannot be attributed exclusively to the intervention.
A Computational Approach to Uncovering The Antibacterial and Anti-Inflammatory Potential of Peptides from Piper Betle L. Leaves Iskandar Iskandar; Gusti Muhammad Perdana Putera; Eko Suhartono; Hapsari Lintang Sekartaji; Windy Yuliana Budianto
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.27571

Abstract

Background: Piper betle L. leaf contains bioactive compounds with potential benefits for oral health. Although its extracts and secondary metabolites have been extensively studied, peptides derived from Piper betle L. leaf proteins remain underexplored as antibacterial and anti-inflammatory agents. Purpose: This study aimed to identify and predict the antibacterial, anti-inflammatory, and toxicity profiles of theoretical peptides generated from a betel leaf protein sequence using a computational approach. Methods: A 561-amino-acid sesquiterpene synthase sequence attributed to Piper betle L. was retrieved from the UniProt database. In silico proteolysis was performed using trypsin, pepsin, and chymotrypsin to generate theoretical peptide fragments of 8–20 amino acids. These peptides represent putative digestion products derived computationally from the selected precursor protein and were not experimentally identified or quantified in Piper betle leaf tissue. Their physicochemical properties were assessed based on molecular weight, hydrophobicity, hydropathicity, hydrophilicity, charge, and isoelectric point. Antibacterial, anti-inflammatory, and toxicity potentials were predicted using AntiBP3, AIPpred, and ToxinPred3, respectively. Results: In silico proteolysis generated nine theoretical peptide sequences with molecular weights ranging from 849.00–1,508.64 Da. GDSPSGVQC, SDPTHETK, and QNIVVAASIICR were predicted to have antibacterial potential, while eight peptides showed anti-inflammatory potential. GDSPSGVQC and DHGCTEEEACMA were predicted to be toxic. SDPTHETK and QNIVVAASIICR showed the most favorable profiles, combining antibacterial and anti-inflammatory potential with predicted non-toxicity. Conclusion: SDPTHETK and QNIVVAASIICR were prioritized as putative peptide candidates based on their predicted antibacterial, anti-inflammatory, and non-toxic profiles. However, these findings are based exclusively on computational analyses and do not demonstrate actual biological activity. Experimental validation is required to confirm their endogenous occurrence, biological activity, safety, and mechanisms of action.
Comparison of Culturable Bacterial Colony Counts from Carious Cavities Between Artisanal Gold Miners and Non-Miners: A Cross-Sectional Study Helena Jelita; Benedikta Cemara Raninai Jakung; Agnes Frethernety; Hanasia Hanasia
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26362

Abstract

Background: Artisanal and small-scale gold mining involves occupational and environmental exposures that may be associated with oral health conditions. However, information on culturable bacterial colony counts obtained from Carious cavities among artisanal gold miners compared with non-miners remains limited. Purpose: This study aimed to compare culturable bacterial colony counts obtained from dental caries swab samples between artisanal gold miners and non-miners with dental caries. Methods: This comparative observational study used a cross-sectional approach. A total of 30 carious cavity swabs were collected from artisanal gold miners and non-miners. Samples were serially diluted up to 10⁻¹⁰ and inoculated on blood agar. Total viable bacterial count was determined using the Total Plate Count (TPC) method and expressed as CFU/mL. Presumptive identification was performed using Gram staining and catalase test. Results: Of 30 samples, 18 met the countable criteria (30–300 colonies), consisting of 11 samples from artisanal gold miners and 7 from non-miners. The miner group showed higher total viable count compared to non-miner group. Independent t-test showed p = 0.605 (p > 0.05), indicating no statistically significant difference in total viable bacterial count from carious cavities. Conclusion: There was no significant difference in total viable bacterial count from carious cavities between groups. Mercury  exposure may affect oral microbiota composition rather than total quantity.
Toxicity and Histological Analysis of Pineapple Core Extract (Ananas Comosus) In Male Wistar Rat Munifah Abdat; Visa Yunanda; Derevie Hensryan Moulina; Afrina Afrina
Dentino: Jurnal Kedokteran Gigi Vol 11, No 2 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i2.26339

Abstract

Bakground: Pineapple core (Ananas comosus) contains bromelain enzyme, which is known to remove dead skin tissue and promote the formation of new tissue. Pineapple fruit and core are also rich in bioactive compounds with potential pharmacological effects. In the oral cavity, it is beneficial in increasing salivary flow. Objective: This study aimed to analyze the toxicity and histological effects of pineapple core extract (Ananas comosus) in male Wistar rats (Rattus norvegicus) using control and treatment groups. Methods: This experimental study used 30 male Wistar rats (Rattus norvegicus), which were administered pineapple core extract supplementation for 14 days. The feed formulation contained pineapple core extract at concentrations of 75% and 90%, with doses ranging from 5,000 mg/kg body weight (BW) to 10,000 mg/kg BW. Histological examination of rat liver tissue was performed at the end of the study. Results: Observation of the control group demonstrated normal liver histology, in which hepatocytes were radially arranged within the hepatic lobules. Similar findings were observed in treatment group (K1), where most hepatocytes appeared normal, with only mild degeneration and necrosis, as well as congestion in the sinusoidal area.Conclusion: Pineapple core extract did not demonstrate toxic effects up to a dose of 10,000 mg/kg BW, although minimal histological alterations in liver tissue were observed.

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