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Nusantara Medical Science Journal
Published by Universitas Hasanuddin
ISSN : 24609757     EISSN : 25977288     DOI : -
Core Subject : Science,
Materials Science & Nanotechnology Neuroscience
Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical problems and molecular mechanisms. Subjects suitable for publication include, but are not limited to the following fields of Cardiovascular; Allergy and immunology; Cancer and stem cells; Endocrinology; Gastroenterology; Tropical and Infectious Disease; and Internal medicine.
Arjuna Subject : -
Articles 112 Documents
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Histopathological Difference of Inflammatory Cells Infiltration into Fetal Membranes of PROM and Non-PROM SUDIARTA, KETUT EDY; FABIOLLA, FABIOLLA; HERDIYANTINI, MITA
Nusantara Medical Science Journal Vol. 10 No. 1 (2025): Volume 10 Issue 1, January - June 2025
Publisher : Faculty of Medicine, Hasanuddin University.

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Abstract

Introduction: Premature rupture of membranes (PROM) remains one of several causes of premature birth that increases both maternal mortality ratio and neonatal mortality rate. Inflammation of fetal membranes leads to release of inflammatory mediators and resulting in weakness of fetal membranes, particularly the amniotic membrane. The amniotic membrane in PROM has a focal weakness, which differs from the membrane in non-premature rupture of membrane (non-PROM) that has a generalized weakness. This research aimed to determine histopathological difference of inflammatory cells infiltration into fetal membranes of PROM and non-PROM.   Methods:  Quantitative observation was applied to this research. Cross-sectional design was used for analyzing data. Primary data was collected from the delivery room and operating theater of Emergency Department in dr. Ramelan Central Naval Hospital (RSPAL dr. Ramelan) Surabaya. Data collection started from August to November 2019 using total population sampling technique. Results: A total of 40 samples histopathologically examined showed that 11 out of 20 (55%) fetal membranes in PROM had polymorphonuclear (PMN) cells infiltration and 9 (45%) did not have PMN cells infiltration, 1 out of 20 (5%) fetal membranes in non-PROM had PMN cells infiltration and 19 (95%) did not have PMN cells infiltration. The prevalence ratio (PR) of PROM based upon the presence of PMN cells infiltration into fetal membranes was 2.85 (PR>1). The significance level of Chi-square test was 0.001 (ρ>0.05). Conclusions: The difference of inflammatory cells infiltration into fetal membranes of PROM and non-PROM was statistically significant.
Thyroglossal Duct Cyst: Clinical Insights from a Case Report Christeven, Robert; Hartungi, Florean
Nusantara Medical Science Journal Vol. 10 No. 1 (2025): Volume 10 Issue 1, January - June 2025
Publisher : Faculty of Medicine, Hasanuddin University.

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Abstract

Introduction and importance: A thyroglossal duct cyst (TGDC) is the most common congenital mass found in the neck region. TGDC originates from the thyroglossal duct and persists along the descending groove of the thyroid gland, from the foramen caecum to the superior thyroid gland in front of the trachea. Presentation of case: A 46-year-old man presented with a slowly enlarging lump at the anterior midline of the neck, first noticed about 10 years earlier. On examination, a well-defined, round, cystic mass measuring 3.5 × 3.3 cm was found superior to the thyroid cartilage. The mass moved with tongue protrusion and swallowing and was mobile, painless, and non-tender. These findings were consistent with a thyroglossal duct cyst. Discussion: Thyroglossal duct cyst (TGDC) is a congenital midline neck mass resulting from the persistence of the thyroglossal duct during thyroid descent. Diagnosis is based on clinical features and imaging, with the Sistrunk procedure serving as the gold standard treatment to prevent recurrence. The patient underwent successful surgical excision without complications, and histopathology confirmed the diagnosis. Conclusions: The Sistrunk's Procedure surgery was conducted successfully with no postoperative complication in this case.

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