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Tatalaksana komprehensif pasien severe xerostomia yang dipicu oleh faktor depresi dan kecemasan: laporan kasus Amira Shafuria; Tenny Setiani Dewi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 1 (2023): April 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i1.41528

ABSTRAKPendahuluan: Xerostomia merupakan keluhan subjektif mulut kering yang dapat disebabkan oleh penurunan sekresi saliva. Sekresi saliva dipengaruhi oleh beberapa faktor seperti faktor usia, terapi radiasi kanker, medikasi, faktor psikologis, serta beberapa faktor lainnya. Laporan kasus ini bertujuan untuk mengetahui pengaruh faktor psikologis terhadap unstimulated salivary flow rate pada pasien severe xerostomia. Laporan kasus: Pasien laki-laki berusia 68 tahun dirujuk dari Departemen Bedah Digestif ke Departemen Ilmu Penyakit Mulut Rumah Sakit Hasan Sadikin (RSHS). Pasien datang dengan keluhan mulutnya terasa kering, sering merasa haus, dan memiliki kesulitan dalam menelan serta berbicara.Pemeriksaan intraoral menunjukkan frothy saliva pada dasar mulut, depapilasi pada dorsum lidah, food debris pada palatum, serta kaca mulut melekat pada dorsum lidah dan mukosa bukal. Laju alir saliva dievaluasi menggunakan pemeriksaan sialometri (unstimulated salivary flow rate <0,1 ml/menit). Pemeriksaan kondisi psikologis dievaluasi menggunakan kuesioner DASS-21 dan menunjukkan tingkat depresi moderate, tingkat kecemasan severe, dan tingkat stres normal. Derajat keparahan xerostomia dievaluasi menggunakan kuesioner VAS (Visual Analogue Scale) Xerostomia. Diagnosis kerja ditegakkan sebagai severe xerostomia berdasarkan skala Challacombe. Penatalaksanaan dari bagian Ilmu Penyakit Mulut antara lain aplikasi petroleum jelly pada bibir dan berkumur menggunakan obat kumur chlorine dioxide patented zinc sebagai stimulator sekresi saliva. Simpulan: Beberapa kondisi psikologis seperti depresi dan kecemasan dapat memengaruhi laju alir saliva yang tidak distimulasi dan menimbulkan kondisi xerostomia. Kata kunci: faktor psikologis, unstimulated salivary flow rate, xerostomia, DASS-21, VASComprehensive management of patient with severe xerostomia triggered by depression and anxiety: a case reportABSTRACTIntroduction: Xerostomia is a subjective complaint of dry mouth resulting from decreased saliva production affected by several factors such as ages, cancer radiation therapies, medication, and psychological factors.This case report aimed to find out the influence of psychological factors on the unstimulated salivary flow rate in a patient with severe xerostomia. Case report: A 68-year-old manwas referred from the digestive surgery department to the Oral Medicine Department of Hasan Sadikin Hospital. The chief complaint was dry mouth, often feeling thirsty, and difficulties in swallowing and speaking. Intraoral examination showed frothy saliva on the floor of the mouth, depapillation on the dorsum of the tongue, and food debris on the palate. The examination using a dental mirror showed that the dental mirror sticks to the tongue and buccal mucosa. Hyposalivation was evaluated using a sialometry test (unstimulated salivary flow rate <0.1 ml/minute). The psychological examination was evaluated using DASS-21 and showed that levels of depression, anxiety, and stress were moderate, severe, and normal respectively. Xerostomia severity was evaluated using VAS (Visual Analog Scale) Xerostomia Questionnaire. The working diagnosis was exfoliative cheilitis and severe xerostomia based on The Challacombe scale. Management from the Department of Oral Medicine includes the application of petroleum jelly on the lips and gargling using chlorine dioxide patented zinc mouthwash as a stimulator of salivary secretion. Conclusion: Psychologicalfactors such as depression and anxiety can influence the unstimulated salivary flow rate and lead to xerostomia.Keywords: psychological factors, unstimulated salivary flow rate, xerostomia, DASS-21, VAS

Pengaruh partikel silver ekstrak daun serai dapur (Cymbopogon citratus DC) terhadap galur sel rongga mulut hsc-3 Hosea Timothy; Komariah Komariah; Didi Nugroho
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 1 (2023): April 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i1.38341

ABSTRAKPendahuluan: Kanker rongga mulut menempati urutan ke-12 dari kasus kanker di dunia. Terapi konvensional memiliki efek samping, sehingga banyak penelitian beralih menggunakan terapi bahan alam seperti sintesis partikel silver dengan daun serai dapur (Cymbopogon citratus DC) sebagai agen antikanker. Sintesis partikel silver ekstrak daun serai dapur dilakukan untuk mereduksi ion logam serta pembentukan partikel logam sehingga meningkatkan aktivitas antikanker, melalui peningkatan produksi reactive oxygen species (ROS) yang menyebabkan depolarisasi membran mitokondria potensial (MMP), sehingga terjadi disfungsi mitokondria sebagai jalur awal terjadinya apoptosis pada galur sel kanker rongga mulut HSC-3. Tujuan Penelitian menganalisis pengaruh pemberian partikel silver ekstrak etanol daun serai dapur terhadap MMP sel HSC-3. Metode: Penelitian dilakukan secara mikroskopis dengan pewarnaan fluorescence untuk melihat MMP menggunakan tetraethylbenzimidazolyl-carbocyanine iodide (JC-1) dan 4′,6-diamidino-2phenylindole (DAPI) sebagai couterstain inti sel. Kelompok penelitian terdiri dari kelompok kontrol, kelompok pembanding dan kelompok yang diberikan perlakuan. Hasil pengamatan memperlihatkan sel dalam kondisi baik akan membentuk agregat J yang terflouresensi merah tertinggi, sedangkan sel yang mengalami apoptosis agregat J akan terflouresensi rendah. Hasil: Kelompok kontrol negatif memperlihatkan pembentukan agregat J dengan intensitas flouresensi merah tertinggi, sedangkan kelompok perlakuan partikel silver ekstrak daun serai dapur 100% memperlihatkan intensitas flouresensi merah terendah (p=0,001) dibandingkan dengan konsentrasi 75, 50, 25, dan 12,5% dan juga kelompok pembanding yang hanya diberikan partikel silver dan ekstrak daun serai dapur. Simpulan: Partikel silver ekstrak etanol daun serai dapur 100% efektif dalam menyebabkan depolarisasi MMP pada HSC-3 dengan intensitas floresensi merah yang lebih rendah.Kata Kunci : ekstrak daun serai, HSC-3, membran mitokondria potensial, partikel silver Effect of silver particles from lemongrass leaves extract (Cymbopogon citratus DC) on Oral Cell Line HSC-3 ABSTRACTIntroduction: Oral cavity cancer ranks 12th of the worldwide cancer cases. Conventional therapy has side effects, so that many studies have switched focus to the use of natural therapies such as synthesis of silver particles from lemongrass leaves (Cymbopogon citratus DC) as an anticancer agent. Synthesis of silver particles of C. citratus leaf extract carried out to reduce metal ions and form metal nanoparticles, thereby increasing anticancer activity by increasing ROS production, which causes depolarization of mitochondrial membrane potential (MMP), resulting in mitochondrial dysfunction as an initial pathway of apoptosis in cancer cell lines. HSC-3. The purpose of this study is to analyze the effect of giving silver nanoparticles from citronella leaves’ ethanol extract on the MMP of HSC-3 cells. Methods: The study was conducted microscopically by fluorescence staining to see MMP using tetraethylbenzimidazolyl-carbocyanine iodide (JC-1) and 4’,6-diamidino-2-phenylindole (DAPI) as cell nucleus counterstains. The research group consisted of a control group, a comparison group, and a treatment group. The results showed that cells in good condition would form J-aggregates with the highest red fluorescence, while cells that underwent J-aggregate apoptosis would have the lowest fluorescence. Results: Negative control group showed the formation of J-aggregates with the highest red fluorescence intensity, while the 100% C. citratus leaf ethanol extract silver particle treatment group showed the lowest red fluorescence intensity (p=0.001) compared to the comparison groups that was only given C. citratus leaf ethanol extract silver particle with concentrations of 75,50, 25, and 12.5%. Conclusion: 100% silver particle ethanol C. citatus leaf extract is effective in causing MMP depolarization of HSC-3 cells with lower red fluorescence intensity.Keywords: lemongrass leaves extract, HSC-3, mitochondrial membrane potential, silver particles

Manifestasi oral dan tatalaksana herpes zoster trigeminal pada anak: A rare case report Fitri Dona Siregar; Ani Megawati; Tenny Setiani Dewi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.46750

ABSTRAK Pendahuluan: Herpes zoster trigeminal adalah penyakit yang menyerang saraf trigeminal karena reaktivasi virus varicella zoster (VZV) yang laten di ganglion saraf trigeminal. Prevalensi herpes zoster pada anak usia di bawah 15 tahun termasuk jarang ditemukan, hanya sekitar kurang dari 10% dan yang melibatkan saraf trigeminal sekitar 18-20% kasus. Laporan kasus ini bertujuan untuk melaporkan penatalaksanaan manifestasi oral herpes zoster trigeminal pada anak. Laporan kasus: Seorang anak laki-laki berusia 9 tahun dikonsulkan oleh bagian Ilmu Kesehatan Anak Divisi Infeksi dan Penyakit Tropis ke Klinik Penyakit Mulut dengan keluhan sariawan sakit pada langit-langit dan pipi sisi kanan. Pemeriksaan ekstra oral menemukan lesi vesikel bula dan krusta multiple unilateral pada wajah dan mata sisi kanan dan kelenjar limfa servikal teraba dengan diameter ± 4-5 cm. Intraoral terdapat krusta serous sanguinolenta pada mukosa labial atas kanan dan ulser dengan dasar putih dikelilingi daerah eritema pada palatum dan mukosa bukal kanan dengan keterbatasan membuka mulut. Berdasarkan pemeriksaan penunjang Tzank Smear, diagnosis kerja ditegakkan sebagai herpes zoster yang terjadi pada regio trigeminal V1-V2 kanan yang menunjukkan gambaran multinucleated giant cell. Terapi yang diberikan berupa acyclovir intravena 400 mg/hari setiap 6 jam, kompres bibir menggunakan kasa yang dibasahi NaCl 0,9%, mengoles tipis vaselin album pada bibir yang kering, dan instruksi menjaga kebersihan rongga mulut. Simpulan: Penatalaksanaan herpes zoster trigeminal pada laporan kasus ini menunjukkan hasil yang baik pada mukosa mulut dan wajah, namun tampak jaringan parut pada wajah sisi kanan sampai vermilion bibir kanan atas.Kata kuncianak, herpes zoster, saraf trigeminal, virus varicella zoster, laporan kasusOral manifestation and management of herpes zoster in children: a rare case reportABSTRACT Introduction: Trigeminal herpes zoster is characterized by the reactivation of the latent varicella-zoster virus (VZV) within the trigeminal nerve, leading to inflammation. This disease predominantly affects the trigeminal nerve due to the reactivation of the latent varicella-zoster virus (VZV) in the trigeminal nerve ganglion. Although herpes zoster cases are relatively rare in children under 15, accounting for only approximately 10% of cases, trigeminal nerve involvement is observed in about 18-20%. This case report presents the management approach to addressing the oral manifestations of trigeminal herpes zoster in pediatric patients. Case Report: A 9-year-old boy was referred from the Children's Health Clinic, Division of Infection and Tropical Disease, to the Oral Medicine Clinic due to complaints of painful canker sores on the palate and right cheek. Multiple unilateral vesicles, bullae, and crusts were observed during the extraoral examination on the face and right eye. Additionally, palpable cervical lymph nodes with a diameter of approximately 4-5 cm were detected. A severe sanguinolent crust was noted on the right upper labial mucosa. Furthermore, an ulcer with a white base, surrounded by an erythematous area, was found on the palate and the right buccal mucosa. The patient exhibited limited mouth opening. Following a Tzank Smear investigation, the working diagnosis was established as herpes zoster, manifesting in the right trigeminal region V1-V2. Multinucleated giant cells were observed in the diagnosis. The therapeutic approach consisted of administering intravenous acyclovir at 400 mg/day, with intervals of every 6 hours. The patient was also advised to apply lip compresses using gauze moistened with 0.9% NaCl and thinly smear Vaseline Album onto dry lips. Instructions were also given for maintaining oral hygiene. Conclusion: The treatment of trigeminal herpes zoster, in this case, report yielded favourable outcomes for the oral and facial mucosa; however, residual scar tissue was evident on the right side of the face, extending up to the vermilion of the right upper lip.Keywordscildren, herpes zoster, trigeminal nerve, varicella zoster virus, case report

Korelasi pengetahuan kesehatan dan kebersihan mulut orang tua dengan kebiasaan menyikat gigi anak: penelitian cross-sectional Muhammad Lutfi Arya Bagus Pangestu; Musnar Munir; Listiyawati Listiyawati
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.46821

ABSTRAKPendahuluan: Orang tua berperan dalam kebiasaan perawatan gigi anak seperti menyikat gigi, diketahui bahwa sebagian besar anak menyikat gigi di waktu yang tidak tepat. Penelitian ini bertujuan menganalisis korelasi pengetahuan kesehatan dan kebersihan mulut orang tua dengan kebiasaan menyikat gigi anak. Metode: Penelitian observasional analitik dengan desain cross-sectional. Jumlah sampel minimal menggunakan rumus Lemeshow dengan derajat penyimpangan 5% dan didapatkan 384 responden yang dipilih dengan teknik purposive sampling. Penelitian dilakukan pada 403 responden di Samarinda bulan Juni-Agustus. Kriteria inklusi yaitu orang tua memiliki anak berumur 6-12 tahun dan bersedia berpartisipasi. Kriteria eksklusi merupakan keluarga single parent dan tidak mengisi kuesioner lengkap. Analisis yang digunakan adalah uji korelasi somers'd untuk menganalisis korelasi antara tingkat pengetahuan kesehatan dan kebersihan mulut orang tua dengan kebiasaan menyikat gigi anak. Hasil: Hasil penelitian menunjukkan rerata skor pengetahuan orang tua sebesar 10,71 dan sebagian besar anak sudah menyikat giginya dua kali sehari setiap harinya akan tetapi masih sedikit yang melakukannya di waktu yang tepat yaitu hanya sebanyak 51 (12,7%). Berdasarkan hasil uji somers’d didapati nilai p untuk korelasi pengetahuan orang tua dengan rutinitas, frekuensi, waktu dan teknik menyikat gigi anak berturut-turut adalah 0,008; 0,011; 0,067; 0,007 dan didapati nilai r=0,098; 0,0112; 0,054; 0,132 dengan arah positif. Simpulan: Terdapat korelasi positif antara tingkat pengetahuan kesehatan gigi dan mulut orang tua dengan rutinitas frekuensi dan teknik menyikat gigi anak, tetapi tidak terdapat korelasi antara tingkat pengetahuan kesehatan gigi dan mulut orang tua dengan waktu menyikat gigi anak.Kata kuncimenyikat gigi, kebersihan mulut, kesehatan mulut, pengetahuan, kebiasaanCorrelation between parents’ oral health and hygiene knowledge with children’s toothbrushing habits: cross-sectional studyABSTRACT Introduction: Parents play a significant role in shaping children's dental care habits, including toothbrushing. Research has revealed that many children brush their teeth at inappropriate times. This study seeks to establish a correlation between parents' knowledge of oral health and hygiene and their children's toothbrushing habits. Methods: This study adopts an analytical observational approach with a cross-sectional design. The minimum required sample size was calculated using the Lemeshow formula, taking into account a 5% margin of error. The resulting sample size was 384 respondents, chosen through purposive sampling. The research was conducted in Samarinda between June and August, involving 403 respondents. The inclusion criteria encompassed parents with children aged 6-12 years willing to participate. Respondents from single-parent households and those who incompletely filled out the questionnaire were excluded. The analysis method employed was the Somers' D correlation test, which assessed the relationship between parents' knowledge levels regarding oral health and hygiene and their children's brushing habits. Results: The research results show the average parental knowledge score was 10.71, and most of the children brushed their teeth twice a day every day, but only a few did it at the right time, only 51 (12.7%). Based on the results of the Somers' D test, the value p for the correlation between parental knowledge and child's routine, frequency, time and brushing technique, respectively, is 0.008; 0.011; 0.067; 0.007 and found a value of r = 0.098; 0.0112; 0.054; 0.132 in a positive direction. Conclusion: There is a correlation between parents' knowledge of dental and oral health and the frequency and technique of their children's toothbrushing routine. However, there is no correlation between parents' knowledge of oral health and the timing at which they have their children brush their teeth.Keywordstoothbrushing, oral hygiene, oral health, knowledge, habit

Efek penggunaan pasta daun tembakau sebagai pembersih gigi tiruan terhadap kekuatan impak nilon termoplastik: Studi eksperimental laboratoris Dewi Kristiana; Hana Fathin Novitasari; Amiyatun Naini
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.47528

ABSTRAK Pendahuluan: Basis gigi tiruan nilon termoplastik memiliki kelebihan yaitu fleksibilitas tinggi dan kekurangan nilon termoplastik yaitu mudah menyerap cairan yang mengakibatkan degradasi polimer dan kekuatan impak menurun. Gigi tiruan dibersihkan untuk mengurangi akumulasi mikroorganisme dan mengatasi denture stomatitis. Gigi tiruan dibersihkan dengan sikat gigi elektrik dan pasta pembersih. Pasta pembersih yang digunakan dari bahan alami yaitu daun tembakau (Nicotiana tabacum L.) yang bersifat antibakteri dan antijamur karena mengandung fenol, alkaloid, saponin, dan minyak atsiri. Tujuan penelitian menganalisis efek penggunaan pasta daun tembakau sebagai bahan pembersih gigi tiruan terhadap kekuatan impak nilon termoplastik. Metode: Jenis penelitian eksperimental laboratoris dengan rancangan the post only group design. Sampel berukuran 65x10x2,5 mm sampel terdiri dari 3 kelompok yaitu kelompok kontrol tanpa penyikatan, kelompok A yaitu nilon termoplastis yang disikat dengan pasta daun tembakau 50%, kelompok B yaitu nilon termoplastis yang disikat dengan pasta daun tembakau 75%. Penyikatan dilakukan selama 730 menit yang setara pembersihan 2 tahun, kemudian diuji kekuatan impaknya. Hasil: Uji One-way Anova menunjukkan perbedaan signifikan pada setiap kelompok p=0,000 (p<0,05). Uji LSD menunjukkan perbedaan bermakna yang signifikan antara kelompok kontrol dan kelompok perlakuan p=0,000 (p<0,05,) sedangkan kelompok pasta daun tembakau 50% dan 75% tidak berbeda signifikan (p=0,411). Simpulan: Pasta daun tembakau 50% dan 75% sebagai pembersih gigi tiruan berpengaruh menurunkan kekuatan impak nilon termoplastik. Kata KunciNilon termoplastik, pasta daun tembakau, kekuatan impakThe Effect of using tobacco leaf paste as a denture cleaner on the impact strength of thermoplastic nylon: experimental laboratory studyABSTRACT Introduction: Thermoplastic nylon denture bases possess the advantage of high flexibility; however, they also have the disadvantage of being prone to absorbing liquids. This characteristic can lead to polymer degradation and a reduction in impact strength. Dentures are cleaned to mitigate the accumulation of microorganisms and to manage denture stomatitis. The cleaning process involves utilizing an electric toothbrush and a cleaning paste derived from Nicotiana tabacum L. (tobacco). The cleaning paste comprises natural ingredients, specifically tobacco leaves, which exhibit antibacterial and antifungal properties due to their phenol, alkaloid, saponin, and essential oil content. This study aimed to assess the impact of using tobacco leaf paste as a cleaning agent for dentures on the impact strength of thermoplastic nylon. Methods: This is a type of laboratory experimental research employing a post-only group design. The samples, measuring 65x10x2.5 mm, were categorized into three groups: the control group without brushing, group A, which involved brushing thermoplastic nylon with 50% tobacco leaf paste, and group B with 75% tobacco leaf paste. Brushing was carried out for 730 minutes, equivalent to 2 years of cleaning, after which the samples were subjected to impact strength testing. Results: The One-way ANOVA test indicated significant differences within each group, with a p-value of 0.000 (p < 0.05). The LSD test demonstrated a significant difference between the control and treatment groups, with a p-value of 0.000 (p < 0.05). Conversely, the groups using 50% and 75% tobacco leaf paste did not exhibit a significant difference, with a p-value of 0.411. Conclusion: Tobacco leaf paste with concentrations of 50% and 75%, when used as a denture cleaner, decreases the impact strength of thermoplastic nylon.Keywords Nylon thermoplastic, tobacco leaf paste, impact strength

Peran kepatuhan pasien pada penatalaksanaan kasus ulser traumatik yang menyerupai Oral Squamous Cell Carcinoma: Laporan kasus Sekar Safitri; Nanan Nur'aeny; Dewi Zakiawati
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.47481

ABSTRAKPendahuluan: Ulser traumatik adalah lesi ulserasi akibat paparan trauma baik mekanis, termal, dan kimia pada mukosa oral. Gambaran klinis ulser traumatik dapat menyerupai gambaran klinis Oral Squamous Cell Carcinoma (OSCC) yang merupakan epithelial cancer. Ulser traumatik dapat bersifat kronis, sehingga diperlukan kepatuhan pasien untuk keberhasilan perawatan. Laporan kasus ini bertujuan untuk menguraikan keberhasilan penatalaksanaan kasus ulser traumatik yang menyerupai OSCC melalui kepatuhan pasien. Laporan Kasus: Seorang perempuan berusia 24 tahun datang untuk kunjungan kontrol pasca satu minggu lesi ulserasi traumatik pada mukosa labial bawah. Pada kunjungan tersebut ditemukan lesi ulserasi baru pada lateral lidah kanan, berjumlah satu buah, berbentuk oval, berukuran ±5 mm, berwarna kekuningan, dikelilingi halo eritema, dangkal, serta berbatas jelas dan tegas. Setelah dua minggu lesi semakin membesar dari ukuran 5 mm menjadi 1 cm disertai indurasi, seperti pada kasus OSCC. Hasil pemeriksaan penunjang hematologi rutin dan hitung jenis leukosit menunjukkan parameter normal, kecuali kadar neutrofil batang di bawah normal. Pasien diberikan edukasi untuk mencegah trauma berulang. Menimbang kondisi pandemi serta kendala jarak, evaluasi dilakukan dengan kontrol berkala secara langsung dan melalui metode teledentistry. Penyembuhan lesi terjadi dalam waktu lama akibat kepatuhan pasien yang kurang terhadap instruksi yang diberikan. Setelah dilakukan edukasi ulang pada pasien, terdapat perbaikan lesi setelah dua bulan pemberian terapi medikasi dan edukasi kepada pasien. Temuan klinis lesi ulserasi traumatik pada rongga mulut yang bersifat kronis perlu ditindaklanjuti terutama apabila menyerupai tanda klinis keganasan. Simpulan: Kepatuhan pasien sangat mendukung keberhasilan dalam penatalaksanaan kasus ulser traumatik kronis yang menyerupai OSCC.Kata kunciulser traumatik, OSCC, kepatuhan pasien, medikasi, edukasi. The role of patient compliance in management of traumatic ulcer mimicking Oral Squamous Cell CarcinomaABSTRACTIntroduction: Traumatic ulcers arise from exposure to mechanical, thermal, and chemical trauma to the oral mucosa. The clinical appearance of traumatic ulcers in the oral cavity may resemble Oral Squamous Cell Carcinoma (OSCC), a type of epithelial cancer. Traumatic ulcers can sometimes become chronic, necessitating patient compliance for effective treatment. This case report aims to depict the successful management of traumatic ulcer cases that mimic OSCC, underscoring the pivotal role of patient compliance in the process. Case Report: A 24-year-old female returned for a follow-up visit one week after developing a traumatic ulcerated lesion on the lower labial mucosa. During the visit, a new solitary ulcerated lesion was discovered on the lateral right side of the tongue. The lesion was oval-shaped, approximately 5 mm in diameter, and exhibited a yellowish hue. It was encompassed by an erythematous halo, appeared shallow, had distinct borders, and displayed firmness. Over two weeks, the lesion had expanded from 5 mm to 1 cm, exhibiting induration. Remarkably, the lesion was painless, which raised concerns about its resemblance to Oral Squamous Cell Carcinoma (OSCC). Haematological investigations and leukocyte count outcomes returned within normal ranges, except for a below-normal count of stem neutrophils. The patient received guidance on measures to prevent re-trauma. Given the prevailing pandemic conditions and limitations in proximity, evaluations were conducted through periodic direct examination and teledentistry. Due to inadequate patient adherence to the provided instructions, the healing process of the lesion was prolonged. Upon patient re-education, a positive response to treatment was observed after two months of medical therapy and education. The clinical improvement underscored the significance of following up on chronic traumatic ulcerated lesions in the oral cavity, remarkably when their clinical presentation resembles signs of malignancy. Conclusion: Patient compliance significantly contributes to the successful management of chronic traumatic ulcer cases resembling OSCC, alongside eliminating underlying etiological factors.Keywordstraumatic ulcer, OSCC, patient compliance, medication, education.

Aktivitas antibakteri ekstrak daun mangga gedong terhadap Streptococcus mutans: Studi eksperimental Vinna Kurniawati Sugiaman; Edward Josse Viando; Natallia Pranata
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.46933

ABSTRAK Pendahuluan: Tingginya prevalensi karies gigi di Indonesia dapat dibuktikan dengan indeks DMF-T di Indonesia 2018 sebesar 7,1. Antibakteri yang dapat digunakan untuk mencegah kondisi tersebut adalah klorheksidin. Namun, klorheksidin memiliki efek samping. Sebagai alternatif digunakan tanaman herbal seperti daun Mangga gedong (Mangifera indica L) yang diduga memiliki efek antibakteri. Penelitian ini bertujuan untuk menganalisis konsentrasi hambat minimal (KHM) dan konsentrasi bunuh minimal (KBM) ekstrak etanol daun Mangifera indica L terhadap pertumbuhan Streptococcus mutans. Metode: Penelitian ini merupakan penelitian eksperimental dengan tujuh kelompok perlakuan, KHM diukur dengan metode mikrodilusi dengan variasi konsentrasi ekstrak (100 mg/ml; 75 mg/ml; 50 mg/ml; 25 mg/ml; 12,5 mg/ml; 6,25% mg/ml; 3,125 mg/ml ml). Klorheksidin 0,2% digunakan sebagai kontrol positif sebagai pembanding. KBM diukur dengan metode TPC dengan menggunakan colony counter. Analisis One Way Anova dengan Post Hoc Tukey digunakan untuk mengetahui perbedaan yang signifikan antara perlakuan. Hasil: Nilai KHM ekstrak daun Mangifera indica L pada konsentrasi 50 mg/ml dan nilai KBM adalah 100mg/ml. Ekstrak Mangifera indica L dengan konsentrasi tertinggi 100mg/mL dan klorheksidin memiliki nilai inhibisi dan viabilitas tertinggi terhadap pertumbuhan S. mutans, namun keduanya tidak berbeda secara signifikan sesuai dengan uji One Way Anova dengan Post Hoc Tukey (p=0,05). Simpulan: Kemampuan daya hambat yang ditunjukkan oleh ekstrak daun Mangifera indica L terhadap pertumbuhan bakteri S. mutans berbanding lurus dengan konsentrasi ekstrak, semakin tinggi konsentrasi ekstrak maka daya hambat yang dihasilkan semakin tinggi.Kata kunciantibakteri, chlorhexidine, ekstrak daun, mangga gedong, streptococcus mutansAntibacterial activity of gedong manggo leeaves Mangifera indica extract against Streptococcus mutans : eksperimental studyABSTRACTIntroduction: The high prevalence of dental caries in Indonesia is evidenced by the DMF-T index data for Indonesia 2018, which stands at 7.1. One common antibacterial medication used to treat this disease is chlorhexidine; however, chlorhexidine is associated with side effects. In search of an alternative, herbal plants are being explored, such as Mangifera indica L (Mango), which is believed to possess antibacterial properties. This study aims to investigate the minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of a 70% ethanol extract obtained from mango leaves against the growth of Streptococcus mutans. Methods: This study is designed as an experimental research involving seven distinct treatment groups. The minimal inhibitory concentration (MIC) was determined using the microdilution method, utilizing a range of extract concentrations: 100 mg/ml, 75 mg/ml, 50 mg/ml, 25 mg/ml, 12.5 mg/ml, 6.25 mg/ml, and 3.125 mg/ml. Chlorhexidine 0.2% was used as a comparative benchmark as the positive control. To assess the minimum bactericidal concentration (MBC), the Total Plate Count (TPC) method was employed, and colony counting was performed. A One-Way ANOVA analysis with Post Hoc Tukey's test was applied to assess significant differences between treatments. Result: The MIC value for the extract of mango gedong leaves was determined to be 50 mg/ml. On the other hand, the MBC value for the gedong mango leaf extract was found to be 100 mg/ml. When comparing the highest concentration of Gedong Mango extract (100 mg/mL) with chlorhexidine, it was observed that both exhibited the highest inhibition and viability values against S. mutans growth. However, according to the One-Way ANOVA test with Post Hoc Tukey analysis (p=0.05), there was no significant difference between the two treatments. Conclusion: The inhibition level demonstrated by the Gedong Mango Leaf extract against the growth of S. mutans bacteria is directly proportional to the concentration level. In other words, as the extract's concentration increases, the inhibition level also increases.Keywords antibacterial, extract, mango gedong leaves, klorheksidin, Streptococcus mutans

Penapisan fitokimia dan kandungan flavonoid total tanaman Calotropis gigantea: Studi eksperimental laboratoris Pudji Astuti; Zahara Meylawaty; Agustin Wulan Suci Dharmayanti; Sari Setyaningsih
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.47123

ABSTRAKPendahuluan: Efek samping penggunaan obat analgesik anti-inflamasi dapat menyebabkan infeksi saluran cerna serius dan dapat berakibat fatal. Tanaman obat biduri (Calotropis gigantea) mempunyai kandungan flavonoid yang berkhasiat analgesik-antiinflamasi, dimana kualitas tanaman obat ditentukan oleh metabolit sekundernya. Kadar flavonoid dan senyawa fenolik lain di dalam tanaman berbeda–beda di setiap bagian, jaringan, dan umur tanaman. Tujuan penelitian ini untuk menganalisis penapisan fitokimia dan kadar flavonoid total dari berbagai bagian tanaman Calotropis gigantea. Metode: Jenis penelitian eksperimental laboratoris yaitu menggunakan ekstrak etanol dari daun, bunga, getah dan kulit akar tanaman Calotropis gigantea, kemudian dilakukan penapisan fitokimia untuk mengetahui adanya metabolit sekunder, seperti alkaloid, tannin, saponin, fenol, steroid dan terpenoid serta flavonoid. Selanjutnya dilakukan pengukuran kadar flavonoid total menggunakan spektrofotometer uv-vis. Data yang diperoleh dianalisis menggunakan independent T-test dengan nilai p=0,05. Hasil: Daun Calotropis gigantea mengandung tanin, saponin, fenol, steroid dan flavonoid; pada bunga mengandung tanin, fenol, steroid dan flavonoid; pada getah mengandung fenol, tannin, saponin dan steroid; pada kulit akar mengandung fenol, tannin, dan terpenoid. Flavonoid ditemukan pada daun dan bunga. Kadar flavonoid total berbeda signifikan antara daun dan bunga, dengan p=0,000<0,05. Simpulan: penapisan fitokimia pada daun, bunga, getah dan kulit akar Calotropis gigantea mengandung fenol, tannin dan steroid. Saponin terdapat pada daun dan getah, sedangkan flavonoid hanya terdapat pada daun dan bunga. Kadar flavonoid total pada daun lebih banyak daripada bunga.Kata kuncicalotropis gigantea, calotropis gigantea, flavonoid, penapisan, fitokimiaScreening of phytochemical and total flavonoid value of Calotropis gigantea plant: Study eksperimental laboratorisIntroduction: Using anti-inflammatory analgesic drugs may lead to severe gastrointestinal infections that could be life-threatening. The medicinal plant Calotropis gigantea contains flavonoids, which possess analgesic and anti-inflammatory properties. The quality of this medicinal plant is contingent on its secondary metabolites. The levels of flavonoids and other phenolic compounds within the plant vary across different parts, tissues, and developmental stages. This study aimed to conduct a phytochemical screening and assess the total flavonoid content in various components of the Calotropis gigantea plant. Method: This laboratory experimental research involves utilizing ethanol extracts from the leaves, flowers, sap, and root bark of the Calotropis gigantea plant. The objective is to conduct a phytochemical screening to identify the presence of secondary metabolites, including alkaloids, tannins, saponins, phenols, steroids, terpenoids, and flavonoids. Subsequently, the total flavonoid content is measured using a UV-vis spectrophotometer. The collected data undergo analysis using an independent t-test, with a significance level set at p = 0.05. Results: show that Calotropis gigantea leaves contain tannins, saponins, phenols, steroids, and flavonoids; flowers contain tannins, phenols, steroids, and flavonoids; the latex contains phenols, tannins, saponins, and steroids; and the root bark contains phenols, tannins, and terpenoids. Flavonoids are present in both leaves and flowers. Notably, the total flavonoid levels exhibited significant differences between leaves and flowers, with a p-value of 0.00 < 0.05. Conclusion: Phytochemical screening of the leaves, flowers, sap, and root bark of Calotropis gigantea revealed the presence of phenols, tannins, and steroids. Saponins were identified in leaves and sap, while flavonoids were exclusively detected in leaves and flowers. Furthermore, the leaves' total flavonoid content was higher than the flowers.Keywordscalotropis gigantea , calotropis gigantea, flavonoids, phytochemical, screening

The radiopacity of glass ionomer cement after addition of nHA powder: experimental study Lusi Hidayati; Supriyadi Supriyadi; Dea Azalia Annisa; Sulistiyani Sulistiyani; Raditya Nugroho; Cortino Sukotjo
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.48594

ABSTRACTIntroduction: One of the restorative materials often used in dental restoration treatment is GIC. One type of GIC is conventional GIC. Conventional GIC has the disadvantage of having low compressive strength compared to resin-modified GIC and high viscosity. One of the efforts to improve the mechanical properties of GIC is by adding nano hydroxyapatite (nHA) which can be obtained from natural materials such as eggshells. The addition of nHA to GIC can increase the compressive strength of GIC and the addition of nHA is thought to result in a change in the radiopacity properties of GIC. The research aims to analyze the radiopacity of GIC after the addition of nano-hydroxyapatite powder. Methods: The number of samples was 24 discs with a diameter of 7 mm and a height of 3 mm which were divided into 4 group. The research group was K0 (GIC) as the control group, K1 (GIC+ 2% nHA), K2 (GIC+ 3% nHA), and K3 (GIC + 4% nHA). Radiopacity measurements were carried out using the J Image application. Results: The results of the ANOVA test was p<0.05, which means that the radiopacity values in each group had a significant difference. The average gray value of GIC without the addition of nHA (K0) was 206.5, GIC + 2% nHA (K1) was 233.0, GIC + 3% nHA (K2) was 237.8 and GIC + 4% nHA (K3) was 241.0 measured with Image J. Conclusions: The addition of nHA powder can increase the radiopacity of GIC and 4% nHA powder added to GIC has the highest radiopacity value compared to 2 and 3% nHA powder added to GIC. .Key words radiopacity, glass ionomer, cement, nHARadiopasitas glass ionomer kaca setelah penambahan bubuk nHA: studi eksperimentalAbstrakPendahuluan: Salah satu bahan restoratif yang sering digunakan dalam perawatan restorasi gigi adalah GIC. Salah satu jenis GIC adalah GIC konvensional. GIC konvensional memiliki kekurangan yaitu kekuatan tekannya rendah dibandingkan dengan GIC yang dimodifikasi resin dan viskositas tinggi. Salah satu upaya untuk meningkatkan sifat mekanik GIC adalah dengan menambahkan nanohidroksiapatit (nHA) yang dapat diperoleh dari bahan alami seperti cangkang telur. Penambahan nHA ke GIC dapat meningkatkan kekuatan tekan GIC dan penambahan nHA diduga mempengaruhi sifat radiopasitas GIC. Penelitian ini bertujuan untuk mengetahui radiopasitas GIC setelah penambahan bubuk nanohidroksiapatit. Metode: Jumlah sampel adalah 24 cakram dengan diameter 7 mm dan tinggi 3 mm yang dibagi menjadi 4 kelompok. Kelompok penelitian ini adalah K0 (GIC) sebagai kelompok kontrol, K1 (GIC+2% nHA), K2 (GIC+3% nHA), dan K3 (GIC+4% nHA). Hasil: Hasil uji ANOVA diperoleh nilai p<0.05 yang berarti bahwa nilai radiopasitas pada setiap kelompok memiliki perbedaan yang signifikan. Rata-rata nilai gray value GIC tanpa penambahan nHA (K0) adalah 206,5, GIC + 2% nHA (K1) adalah 233,0, GIC + 3% nHA (K2) adalah 237,8 dan GIC + 4% nHA (K3) adalah 241,0. Simpulan: Penambahan bubuk nHA dapat meningkatkan radiopasitas GIC dan 4% bubuk nHA yang ditambahkan ke GIC memiliki nilai radiopasitas tertinggi dibandingkan dengan 2 dan 3% bubuk nHA yang ditambahkan ke GIC.Kata kunciradiopasitas, semen, glass ionomer, nanohidroksiapatit

Korelasi perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi pada remaja: studi cross-sectional Andriono Dermawan; Surartono Dwiatmoko; Leni Rokhma Dewi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.47155

ABSTRAKPendahuluan: Kesehatan gigi dan mulut merupakan hal yang penting untuk dijaga karena dapat memengaruhi kesehatan seluruh tubuh. Hal yang dapat memengaruhi kesehatan gigi dan mulut ada perilaku. Perilaku pencarian informasi dan perilaku kesehatan gigi dan mulut dapat dipengaruhi oleh faktor sosiodemografi. Remaja memiliki rasa ingin tahu yang tinggi, tetapi biasanya tidak mengevaluasi sumber informasi yang mereka gunakan. Penelitian ini bertujuan menganalisis korelasi perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi pada remaja. Metode: Jenis penelitian observasional analitik dengan rancangan cross-sectional menggunakan instrumen kuesioner. Variabel penelitian adalah perilaku pencarian informasi kesehatan gigi dan mulut dan faktor sosiodemografi (usia, jenis kelamin, tempat tinggal, pendidikan orang tua, dan pendapatan orang tua). Populasi penelitian adalah siswa SMP tahun ajaran 2021/2022 semester gasal sebanyak 70.913. Teknik penentuan jumlah sampel menggunakan rumus Slovin. Sampel diambil menggunakan teknik random cluster random sampling. Distribusi secara proporsional menggunakan rumus oleh Bowley. Data dianalisis menggunakan uji non parametric, yaitu Spearman Rank Correlation. Hasil: Nilai signifikansi untuk variabel perilaku pencarian informasi dengan variabel usia (p=0,001), jenis kelamin (p=0,000), pendidikan orang tua (p=0,000), dan pendapatan orang tua (p=0,000), dan lokasi tempat tinggal (p=918). Korelasi termasuk sedang pada daerah perkotaan (0,410) dan lemah pada daerah pegunungan (0,410) dan dataran rendah (0,314). Nilai hasil uji Spearman Rank Correlation menunjukkan bahwa perilaku pencarian informasi kesehatan gigi dan mulut berkorelasi dengan usia, jenis kelamin, pendidikan orang tua, dan pendapatan orang tua, sedangkan dengan lokasi tempat tinggal tidak berkorelasi. Simpulan: Terdapat korelasi antara perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi usia, jenis kelamin, pendidikan orang tua, dan pendapatan orang tua remaja di Kabupaten Jember, sedangkan variabel tempat tinggal tidak menunjukkan korelasi yang bermaknaKata kunciperilaku, informasi, kesehatan gigi dan mulut, faktor sosiodemografi, remajaCorrelation of oral health information seeking behavior with sociodemographic factors in adolescents: cross-sectional study ABSTRACTIntroduction: Maintaining dental and oral health is crucial as it can impact the body's overall well-being. Various factors can influence dental and oral health; among them, behaviours play a significant role. These behaviours encompass seeking information about dental and oral health and sociodemographic factors that can influence them. While often curious, teenagers overlook the evaluation of information sources they employ. This study examines the correlation between adolescents' behaviour in seeking oral health information and sociodemographic factors. Methods: This study employs an analytical observational research approach with a cross-sectional design, employing a questionnaire as the research instrument. The study focuses on two main variables: dental and oral health information-seeking behaviour and sociodemographic factors, including age, gender, place of residence, parental education, and parental income. The research population comprises 70,913 junior high school students from odd semesters during the 2021/2022 academic year. The sample size was determined using the Slovin formula, and the samples were collected using a random cluster random sampling technique. To ensure representativeness, the samples were distributed proportionately according to the formula introduced by Bowley. A non-parametric statistical test, specifically the Spearman Rank Correlation, was employed for data analysis. Results: The significance values for the information-seeking behaviour variable were as follows: age (p=0.001), gender (p=0.000), parental education (p=0.000), parental income (p=0.000), and location of residence (p=0.918). The correlation was moderate in urban areas (0.410), weak in mountainous areas (0.410), and coastal areas (0.314). The Spearman Rank Correlation test results indicated that dental and oral health information-seeking behaviour was associated with age, gender, parental education, and parental income. However, no significant relationship was found between dental and oral health information-seeking behaviour and the location of residence. Conclusion: Correlation of dental and oral health information-seeking behaviour and sociodemographic factors, including age, gender, parental education, and parental income, among adolescents in Jember Regency. However, the variable of residence does not exhibit a significant correlation.Keywordsbehavior, information, dental and oral health, sociodemographic factors, adolescents

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Abstract

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Cecilia Soeriawidjaja

Contact Email cecilia.soeriawidjaja@unpad.ac.id

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Journal Mail Official jurnal.fkg@unpad.ac.id

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Location Kota bandung, Jawa barat INDONESIA

Abstract

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Abstract

Abstract

Abstract

Abstract

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Abstract

Contact Name
Cecilia Soeriawidjaja

Contact Email
cecilia.soeriawidjaja@unpad.ac.id

Phone
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Journal Mail Official
jurnal.fkg@unpad.ac.id

Editorial Address
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Location
Kota bandung,

Jawa barat

INDONESIA