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HUBUNGAN JUMLAH SEL NEUTROFIL DENGAN KADAR TROPONIN I PADA PENDERITA INFARK MIOKARD AKUT Candra Triana Hikma; Handayati Anik; Endah Astuti Sri Sulami
Analis Kesehatan Sains Vol. 10 No. 2 (2021): Analis Kesehatan Sains
Publisher : Jurusan Teknologi Laboratorium Medis Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (656 KB)

Acute Myocardial Infarction (AMI) is a heart disease condition due to heart muscle cells not getting enough blood flow and oxygen due to atherosclerosis of the coronary arteries. When the condition of atherosclerosis gets worse, it will cause an inflammatory reaction, causing an increase in neutrophils. Inflammation due to atherosclerosis will worsen blood flow to the heart, resulting in heart muscle necrosis which causes an increase in biochemical markers, namely cardiac troponin. The aim of this research is to determine the relationship between the number of neutrophil cells and troponin I levels in patients with Acute Myocardial Infarction.This type of research is a cross-sectional analytic observational with a retrospective approach. This research was conducted on patients with Acute Myocardial Infarction at the RSPAL dr. Ramelan Surabaya who performed a complete blood count and troponin I level with a period of January 1st 2020 – May 3rd 2021, taken by purposive sampling. The results showed that male respondents were 29 patients (63%) while female respondents were 17 patients (37%). Respondents aged 65 years amounted to 28 (61%) people, while respondents aged 65 years were 18 (39%) people. The results of the hypothesis test have a sig value of 0.000 < (0.05), so there is a relationship between the number of Neutrophil cells and Troponin I level in patients with Acute Myocardial Infarction. In hypothesis testing, the correlation coefficient value is 0.594, which means that there is a moderate relationship with a positive direction.

Pemeriksaan Status Gizi dan Kadar Asam Urat Lansia di Posyandu Abiyoso Polkesbaya Evy Diah Woelansari; Juliana Christyaningsih; Suhariyadi Suhariyadi; Lully Hanni Endarini; Museyaroh Museyaroh; Diah Titik Mutiarawati; Wisnu Istanto; Suliati Suliati; Anik Handayati; Sri Sulami Endah Astuti; Pestariati Pestariati; Retno Sasongkowati; Mamik Mamik; Sri Utami; Minarti Minarti; Luthfi Rusyadi; Liliek Soetjiatie
Jurnal Pengabdian Kesehatan Beguai Jejama Vol 4, No 2 (2023): Jurnal Pengabdian Kesehatan Beguai Jejama Volume 4 Nomor 2 Agustus 2023
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jpk.v4i2.13417

Proses penuaan dapat memengaruhi kesehatan fisik lansia dan meningkatkan risiko berbagai gangguan kesehatan, termasuk hipertensi dan asam urat. Kegiatan ini berlangsung pada tanggal 14 Juni 2023 bertempat di Balai RW 2 Kelurahan Kertajaya, Surabaya dan dihadiri 59 lansia yang berdomisili di RW 1 dan RW 2 Kelurahan Kertajaya Kecamatan Gubeng Surabaya. Jenis kegiatan yang dilaksanakan adalah pengukuran status gizi, asam urat dan senam hipertensi. Hasil pemeriksaan mengungkapkan 57,6% lansia memiliki kadar asam urat yang tinggi dan mayoritas memiliki kelebihan berat badan, sehingga lansia perlu mengendalikan tekanan darah dengan pengobatan yang diresepkan oleh dokter, perubahan gaya hidup seperti diet rendah garam, olahraga teratur, dan menghindari stres.

Diagnostic Test of FNAB Towards Histopathology in Lipoma Soft Tissue Tumor Patients: Uji Diagnosis FNAB Terhadap Histopatologi Pada Pasien Tumor Jaringan Lunak Lipoma Jihan Azzahra Arsyi; Handayati, Anik; Sri Sulami Endah Astuti
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1653

Lipomas are the most common soft tissue tumor neoplasms. Their range from benign lipomas to high grade liposarcomas. Liposarcoma happens when the neoplasm of a lipoma is malignant. There are various diagnostic methods that can be used to evaluate lipomas, one of which is Fine Needle Aspiration Biopsy (FNAB). FNAB is the initial diagnosis to determine the diagnosis of lipoma soft tissue tumors. Histopathology is the definitive diagnosis or the gold standard for diagnosing lipoma soft tissue tumors. This research aims to determine the value of the Fine Needle Aspiration Biopsy diagnostic test against histopathological tests as the gold standard in lipoma soft tissue tumor patients. This research is a retrospective with a descriptive observational design. This research involved taking medical records of patients with lipoma soft tissue tumors who were examined by FNAB at RSPAL dr. Ramelan, Surabaya for the period August 2019 - December 2021. The results of the FNAB examination were then matched against the histopathological examination data as the gold standard. Data processing using 2x2 cross tabulation to calculate the diagnostic test which includes sensitivity, specificity, positive predictive value, negative predictive value, and accuracy against the gold standard. The results of the Fine Needle Aspiration Biopsy diagnostic test for histopathology in soft tissue lipoma tumors obtained sensitivity of 100.00%, specificity 95.83%, positive predictive value (NRP) 87.5%, negative predictive value (NRN) 100.00%, and 96.77% accuracy. Fine Needle Aspiration Biopsy (FNAB) has good diagnostic value for diagnosing lipoma soft tissue tumors.

PERBANDINGAN HASIL LAJU ENDAP DARAH METODE WESTERGREN DENGAN MENGGUNAKAN ANTIKOAGULAN EDTA DAN NATRIUM SITRAT 3,8% PADA WANITA MENSTRUASI Atsania Putri , Puji Lestari; Anik, Handayati; Sri Sulami , Endah Astuti
Analis Kesehatan Sains Vol. 10 No. 1 (2021): Analis Kesehatan Sains
Publisher : Politeknik Kesehatan Kementerian Kesehatan Surabaya

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The Erythrocyte sedimentation rate is a routine blood test performed to monitor the course of the disease where high values are likely to be associated with the presence of inflammation. ICSH (International Council for Standardization in Hematology) recommends the Westergren method as a method for examining LED with several developments in terms of the anticoagulants and diluents used. Anticoagulants that can be used are Sodium Citrate 3,8% anticoagulant and EDTA (Ethylene Diamine Tetra-Acetid-Acid) anticoagulant. This study aims to determine the differences in the erythrocyte sedimentation rate of the westergren method using EDTA anticoagulants and sodium citrate 3.8%.This study uses primary data collection techniques with comparative research type. The research was conducted at the Health Analyst Laboratory of Poltekkes Kemenkes Surabaya, in January-April 2021. The sample of the study was 50 menstruating women who had met several criteria, who would be examined for LED values using the Westergren method using EDTA anticoagulants in purple vacuum tubes and sodium citrate 3,8 % on a black vacuum tube.The results showed that the mean of sedimentation rate with EDTA anticoagulant was 27.66 mm/hour and 22.04 mm/hour for sodium citrate 3,8% anticoagulant. The statistical test was carried out by using the paired sample t-test which showed the sig (p) value = 0.000 0.05, so it could be concluded that there was a difference between the EDTA anticoagulant LED and the sodium citrate anticoagulant LED. Thus the EDTA anticoagulant can still be used as an anticoagulant in examining the erythrocyte sedimentation rate

HUBUNGAN JUMLAH SEL NEUTROFIL DENGAN KADAR TROPONIN I PADA PENDERITA INFARK MIOKARD AKUT Hikma , Candra Triana; Anik, Handayati; Sri Sulami , Endah Astuti
Analis Kesehatan Sains Vol. 10 No. 2 (2021): Analis Kesehatan Sains
Publisher : Politeknik Kesehatan Kementerian Kesehatan Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/anakes.v10i2.20

Acute Myocardial Infarction (AMI) is a heart disease condition due to heart muscle cells not getting enough blood flow and oxygen due to atherosclerosis of the coronary arteries. When the condition of atherosclerosis gets worse, it will cause an inflammatory reaction, causing an increase in neutrophils. Inflammation due to atherosclerosis will worsen blood flow to the heart, resulting in heart muscle necrosis which causes an increase in biochemical markers, namely cardiac troponin. The aim of this research is to determine the relationship between the number of neutrophil cells and troponin I levels in patients with Acute Myocardial Infarction.This type of research is a cross-sectional analytic observational with a retrospective approach. This research was conducted on patients with Acute Myocardial Infarction at the RSPAL dr. Ramelan Surabaya who performed a complete blood count and troponin I level with a period of January 1st 2020 – May 3rd 2021, taken by purposive sampling. The results showed that male respondents were 29 patients (63%) while female respondents were 17 patients (37%). Respondents aged 65 years amounted to 28 (61%) people, while respondents aged 65 years were 18 (39%) people. The results of the hypothesis test have a sig value of 0.000 < (0.05), so there is a relationship between the number of Neutrophil cells and Troponin I level in patients with Acute Myocardial Infarction. In hypothesis testing, the correlation coefficient value is 0.594, which means that there is a moderate relationship with a positive direction.

IDENTIFIKASI TELUR CACING ASCARIS LUMBRICOIDES PADA KEMBANG KOL (BRASSICA OLERACEA VAR. BOTRYTIS) DENGAN METODE SEDIMENTASI Choirudin, Nadia Pramesthy Choirudin; Sasongkowati, Retno; Astuti, Sri Sulami Endah
Journal of Indonesian Medical Laboratory and Science Vol 5 No 1: April 2024
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v5i1.178

Background: Ascaris lumbricoides is the causative agent of a helminthic diseases known as ascariasis. According to the World Health Organization (WHO), helminthic diseases constitute more than half of the health issues in developing countries. It is caused by poor sanitation and a tropical climate that supports the development of worms. Transmission of worm eggs to humans can be through vegetables that grow near the ground, one of them is cauliflower. Objectives: The study aimed to identify the presence of Ascaris lumbricoides eggs in cauliflower sold at Krembung Market, Sidoarjo Regency. Materials and Methods: The method used is sedimentation using 0,2% NaOH reagent with the principle of centrifugal force which results in the separation of worm eggs and supernatant. This method can precipitate eggs without damaging them, making it easier to identify the type of worm eggs. Results: The research was carried out in April 2023 and the results showed that from the 12 samples sold on mats, there were 2 samples (17%) contaminated with infertile Ascaris lumbricoides eggs. Meanwhile, from 12 samples sold on table, no Ascaris lumbricoides eggs (0%) were found. Conclusions: Based on the research results, Ascaris lumbricoides eggs were found in 2 out of 12 samples of cauliflower sold on mats.

Pemanfaatan Kacang Kedelai (Glycine max (L.) Merill) Varietas Anjasmoro dan Dega-1 Sebagai Media Alternatif PDA (Potato Dextrose Agar) untuk Pertumbuhan Candida Albicans Putri, Ervina Wahyu; Sasongkowati, Retno; Astuti, Sri Sulami Endah; Istanto, Wisnu
Jurnal Penelitian Kesehatan SUARA FORIKES 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf14nk123

PDA (Potato Dextrose Agar) is a medium containing many nutrients needed by fungi, especially Candida albicans. Several researchers found alternative media for fungal growth using various carbohydrate sources such as cassava dextrose agar, canna tubers, yam tubers and arrowroot tubers on Candida albicans and Aspergillus niger. One of the components contained in PDA media is carbohydrates. Soybeans (Gllycine Max L. Merill) are a source of carbohydrates which are usually used as ingredients for food and beverage preparations (such as soy sauce, tempeh, tofu, and milk). Several soybean varieties that are included in the top 10 best quality with high nutritional content are the Anjasmoro variety and the Dega-1 variety. This study aimed to answer that the soybean (Glycine max (L.) Merill) varieties Anjasmoro and Dega-1 can be used as an alternative PDA medium for the growth of Candida albicans. The research method used was experimental to test the potential of the Anjasmoro variety and the Dega-1 variety as alternative media for PDA by analyzing the growth characteristics of Candida albicans with variations in the mass of soybean powder for each variety. The results showed that soybean variety Anjasmoro variety was better than soybean variety Dega-1 and has the potential to be an alternative media because the average number of colonies and morphology of Candida albicans at 4.4 gram mass variation was almost equivalent to the fungus growing on Gold media standard.Keywords: Candida albicans; Potato Dextrose Agar; soybean variety Anjasmoro; soybeans of the Dega-1 variety ABSTRAK PDA (Potato Dextrose Agar) merupakan media berisi banyak kandungan nutrisi yang dibutuhkan oleh jamur terutama Candida albicans. Beberapa peneliti menemukan media alternatif untuk pertumbuhan jamur menggunakan berbagai sumber karbohidrat seperti singkong dextrose agar, umbi ganyong, umbi gembili dan umbi garut pada Candida albicans dan Aspergillus niger. Salah satu komponen yang terdapat dalam media PDA yaitu karbohidrat. Kacang kedelai (Gllycine Max L. Merill) merupakan sumber karbohidrat yang biasanya dimanfaatkan sebagai bahan olahan makanan dan minuman (seperti kecap, tempe, tahu, dan susu). Beberapa varietas kacang kedelai yang termasuk 10 besar kualitas terbaik dengan kandungan gizi yang tinggi yaitu varietas Anjasmoro dan varietas Dega-1. Penelitian ini bertujuan untuk menjawab bahwa kacang kedelai (Glycine max (L.) Merill) varietas Anjasmoro dan Dega-1 dapat dimanfaatkan sebagai media alternatif PDA untuk pertumbuhan Candida albicans. Metode penelitian yang digunakan adalah eksperimental untuk menguji potensi kacang kedelai varietas Anjasmoro dan Varietas Dega-1 sebagai media alternatif PDA dengan menganalisis karakteristik pertumbuhan Candida albicans dengan variasi massa serbuk kacang kedelai masing-masing varietas. Hasil penelitian menunjukkan bahwa kacang kedelai varietas Anjasmoro lebih baik dibandingkan kacang kedelai varietas Dega-1 dan berpotensi untuk menjadi media alternatif dikarenakan pada rata-rata jumlah koloni dan morfologi Candida albicans pada variasi massa 4,4 gram hampir setara dengan jamur yang tumbuh pada media Gold standart.Kata kunci: Candida albicans; Potato Dextrose Agar; kacang kedelai varietas Anjasmoro; kacang kedelai varietas Dega-1

Pendampingan dan Peningkatan Pengetahuan Manfaat Infusa Bawang Putih pada Masyarakat dalam Mencegah dan Mengatasi Hipertensi pada Masyarakat di Desa Ketetang Kecamatan Kwanyar Kabupaten Bangkalan Haryanto, Edy; Astuti, Sri Sulami Endah; Sasongkowati, Retno; Anita Dwi Anggraini
ABDIKESMAS MULAWARMAN : Jurnal Pengabdian Kepada Masyarakat Vol.3 No.1 Mei (2023) : ABDIKESMAS MULAWARMAN
Publisher : Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/abdikesmasmulawarman.v3i1.152

Hipertensi merupakan penyakit degeneratif yang menjadi masalah serius saat ini. Bahaya hipertensi yang tidak dapat dikendalikan dapat menimbulkan komplikasi yang berbahaya, seperti penyakit jantung koroner, stroke, ginjal dan gangguan penglihatan. Beberapa faktor yang berperan dalam terjadinya hipertensi meliputi faktor mayor yaitu faktor risiko yang tidak dapat dikendalikan dan faktor minor yaitu faktor risiko yang masih dapat dikendalikan. Permasalahan yang terjadi pada masyarakat adalah kurangnya pengetahuan tentang pengendalian penyakit hipertensi serta faktor-faktor yang mempengaruhi kejadian hipertensi dan ketidaktahuan masyarakat dalam memanfaatkan bahan herbal yang ada disekitar untuk dimanfaatkan untuk menurunkan hipertensi yaitu contohnya bawang putih. Kegiatan pengabdian masyarakat yang dilakukan pada warga di Desa Ketetang dusun kwalas berhasil dilaksanakan dan diikuti sebanyak 31 orang yang mengikuti pemeriksaan tekanan darah, kegiatan pelatihan dan penyuluhan pembuatan dan pemanfaatan infusa bawang. Masalah kesehatan yang dikeluhkan oleh warga mampu diatasi oleh tim pengabdian masyarakat dengan memberikan edusi pelatihan dan penyuluhan pembuatan infusa bawang putih sebagai terapi dari herbal untuk menurunkan tekanan darah. Selama kegiatan berlangsung peserta sangat antusias, hal ini dapat dilihat pada keaktifan peserta mengikuti dari awal sampai akhir.

Pendampingan dan Pemanfaatan Infusa Jahe untuk Meningkatkan Imunitas Tubuh pada Para Petani yang Terinfeksi Kecacingan di Desa Ketetang Kecamatan Kwanyar Kabupaten Bangkalan Astuti, Sri Sulami Endah; Haryanto, Edy; Arifin, Syamsul; Anita Dwi Anggraini
ABDIKESMAS MULAWARMAN : Jurnal Pengabdian Kepada Masyarakat Vol.3 No.1 Mei (2023) : ABDIKESMAS MULAWARMAN
Publisher : Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/abdikesmasmulawarman.v3i1.153

Pekerjaan yang sangat erat kaitannya dengan infeksi STH yang berhubungan dengan tanah yaitu petani. Dusun Ketetang merupakan desa terpencil yang mayoritas penduduknya bekerja sebagai petani. Petani yang dalam kesehariannya bekerja tidak menggunakan alat pelindung diri seperti sarung tangan dan alas kaki, yang secara langsung kontak dengan tanah, selain itu para petani juga mengonsumsi makanan tanpa mencuci tangan dengan bersih terlebih dahulu. Petani dapat terinfeksi cacing baik melalui oral yaitu melalui makanan dan minuman yang tercemar dan melalui penetrasi kulit dengan adanya kontak langsung dengan kotoran hewan yang digunakan sebagai pupuk tanaman . Penelitian angka kecacingan tahun 2019 yang dilakukan oleh Lisma mahasiswa D3 Jurusan Analis Kesehatan menunjukkan hasil yaitu terd apat 40 responden (80%) yang infeksi Soil Transmitted Helminths dan 10 responden (20%) yang tidak terinfeksi Soil Transmitted Helminths pada petani di Koalas Bangkalan Madura. Ang ka kecacingan yang tinggi ini juga diikuti oleh penurunan kadar hemoglobin yang merupakan dampak akibat infeksi kecacingan. Hasil ini menunjukkan angka kecacingan yang tinggi disertai anemia sehingga masyarakat di Desa Ketetang masih memerlukan edukasi tentang pentingnya Pola Hidup Bersih dan sehat dan penggunaan Alat Pelindung diri untuk mencegah penyakit kecacingan STH, serta mengetahui dan mengkonsumsi jenis makanan sehat yang mampu meningkatkan kadar hemoglobin. Masalah ini terjadi karena kurangnya para petani dalam menjaga sistem imun tubuh sehingga mudah terinfeksi parasit, serta kurangnya pengetahuan tentang pemanfaatan herbal khususnya jahe merah dalam menjaga kesehatan diri oleh para petani. Solusi yang ditawarkan adalah menggerakkan para petani untuk mengkonsumsu infusa jahe dan mengedukasi pentingnya menjaga sistem imun, pembuatan infusa jahe yang benar sehingga nilai gizi dan manfaatnya tidak hilang.

Pap Smear Diagnostic Test Towards Gold Standard Histopathology In Cervic Cancer: Uji Diagnostik Pap Smear Terhadap Gold Standard Histopatologi Pada Kanker Serviks Anik Handayati; Putri, Tiara Dewanti; Sri Sulami Endah Astuti
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1655

Cervical cancer is the second most common cancer in the world. Screening examination plays an important role in early detection of cervical cancer so that it can reduce mortality. Pap smear is an initial examination to detect the presence of abnormal cells in the cervix. This study aims to determine the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of pap smear examination by comparing them to histopathological examination as the gold standard. The design of this study was an observational study with secondary data obtained from the medical records of cervical cancer patients who had performed pap smears as well as histopathological examinations at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya for the period January 2020 to March 2022. The data will be sorted based on inclusion and exclusion criteria. Data that pass the inclusion criteria will be tested using crosstabulation and then proceed to the diagnostic test. The sensitivity value is 97%, specificity value is 88%, accuracy value is 96%, positive predictive value is 98%, and negative predictive value is 79%. Pap smears have a fairly good diagnostic value for diagnosing cervical cancer.

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