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All Journal Media Ilmu Kesehatan JUSTER: Jurnal Sains dan Terapan
Hari Untarto Swandono
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
Biochemistry, Genetics & Molecular Biology Chemistry Energy Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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FORMULASI SEDIAAN SERUM DARI KULIT BUAH DURIAN BERBAGAI VARIETAS (Durio zibethinus Murray) LOKAL, MONTONG DAN MUSANG KING Hari Untarto Swandono; Sony Andika Saputra; Maria Magdalena Riyaniarti Estri Wuryandari; M. Nur Husna
MEDIA ILMU KESEHATAN Vol 15 No 1 (2026): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v15i1.1787

Abstract

Background: Durian peel (Durio zibethinus Murr.), which is often discarded as agricultural waste, contains bioactive compounds such as flavonoids and tannins that exhibit antibacterial properties, particularly against acne-causing bacteria Objective: This study aimed to evaluate the physical characteristics and stability of a serum formulation prepared with durian peel extract (Durio zibethinus Murr.) at a concentration of 15% and to compare the physical stability among different durian varieties.Methods: The durian peel extract was obtained using the maceration method with 96% ethanol as the solvent and then formulated into a serum preparation. Physical quality evaluations included tests for color, homogeneity, pH, spreadability, adhesion, and viscosity. Results: The Musang King variety produced the best formulation, characterized by a yellowish-brown color and homogeneous appearance. The pH remained stable between 4.67 and 6.65 before and after stability testing. Conclusion: The durian peel extract–based serum demonstrated good physical quality and stable characteristics during storage, suggesting its potential use as a natural active ingredient in cosmetic formulations for acne-prone skin care
Formulasi dan Uji Stabilitas Lotion Repelen Daun Paitan: Pendekatan Fisikokimia Untuk Pengendalian Aedes aegypti Dwi Wahyuni; Arshy Prodyanatasari; Asih Imulda Hari Purwani; Anik Andayani; Hari Untarto Swandono; Pavitra Meilina Imanda’ar
JUSTER : Jurnal Sains dan Terapan Vol. 5 No. 1 (2026): JUSTER: Jurnal Sains dan Terapan
Publisher : Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/juster.v5i1.2281

Abstract

Tingginya kasus DBD di Indonesia mendorong inovasi lotion anti nyamuk yang aman. Urgensi penelitian muncul dari risiko iritasi kulit akibat penggunaan produk sintetis berbasis DEET. Gap penelitian terletak pada belum adanya formulasi lotion berbasis ekstrak daun paitan yang dilengkapi dengan data uji stabilitas fisik dan efektivitasnya sebagai penolak nyamuk Aedes aegypti. Penelitian ini bertujuan memformulasikan lotion ekstrak etanol daun paitan konsentrasi 15% dan mengevaluasi karakteristik fisik, stabilitas, serta efektivitasnya sebagai penolak nyamuk Aedes aegypti. Penelitian ini merupakan penelitian eksperimental, meliputi ekstraksi daun paitan, formulasi lotion, dan uji stabilitas menggunakan metode freeze and thaw. Parameter uji meliputi organoleptis, homogenitas, pH, jenis emulsi, kemampuan daya lekat dan sebarnya, serta efektivitas repellent. Hasil evaluasi terlihat bahwa sediaan lotion memenuhi semua persyaratan uji karakteristik fisik. Uji efektivitas pada manusia menunjukkan daya proteksi yang sangat tinggi, yaitu 97% sebelum uji stabilitas dan 93% setelahnya, meskipun terjadi sedikit perubahan pada semua parameter fisik pasca uji stabilitas. Lotion ekstrak etanol daun paitan 15% memenuhi syarat karakteristik sediaan topikal dan efektif sebagai penolak nyamuk Aedes aegypti dengan daya proteksi tinggi (97% sebelum dan 93% setelah uji stabilitas).
Co-Authors Arshy Prodyanatasari Asih Imulda Hari Purwani DWI WAHYUNI M. Nur Husna MM.Riyaniarti Estri Wuryandari Pavitra Meilina Imanda’ar