Article Per Year (5 Year)
p-Index From 2021 - 2026
2.195
P-Index
This Author published in this journals
All Journal Althea Medical Journal Global Medical and Health Communication The Indonesian Biomedical Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Abdi Insani Jurnal Integrasi Kesehatan dan Sains Jurnal Riset Kedokteran Bandung Conference Series : Medical Science
Raden Anita Indriyanti
Departemen Farmakologi Fakultas Kedokteran Universitas Islam Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 18 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 18 Documents
Search

 1   2 
Pola Penggunaan Gawai pada Anak dengan Gangguan Bahasa Ekspresif di RSUD Al-Ihsan Bandung Mayka Adisti Yunus; R. Anita Indriyanti; Miranti Kania Dewi
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.11187

Abstract

Abstract. Based on data from the Centers for Disease Control and Prevention (CDC), children generally spend about eight hours a day watching digital screens. The World Health Organization (WHO) recommends screen time of no more than one hour for children between the ages of two and four. Language disorders are often associated with high screen time. This study aims to determine the description of demographic characteristics and patterns of device use in children with expressive language disorders at Al Ihsan Bandung Hospital. This study is descriptive in nature with research subjects of children who have expressive language disorders at Al Ihsan Hospital who meet the inclusion criteria. The results of this study indicate that most pediatric patients with language disorders at Al-Ihsan Bandung Hospital in 2023 are children who use 2 types of devices (46.7%) with the most frequently used device is television (100%) and the duration of use is included in the long category (>60 minutes) (93.3%). All children with expressive language disorders at Al-Ihsan Bandung Hospital have a history of excessive device use. The higher the use of devices in children will affect the development of language in children. Abstrak. Berdasarkan data dari Centers for Disease Control and Prevention (CDC), anak-anak umumnya menghabiskan waktu sekitar delapan jam sehari untuk menonton layar digital. World Health Organization (WHO) merekomendasikan screen time tidak lebih dari satu jam untuk anak antara usia dua dan empat tahun. Gangguan berbahasa sering kali dikaitkan dengan screen time yang tinggi. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik demografi dan pola penggunaan gawai pada anak dengan gangguan bahasa ekspresif di RSUD Al Ihsan Bandung. Penelitian ini bersifat deskriptif dengan subjek penelitian anak yang memiliki gangguan bahasa ekspresif di RSUD Al Ihsan yang memenuhi kriteria inklusi. Hasil penelitian ini menunjukkan bahwa sebagian besar pasien anak dengan gangguan bahasa di RSUD Al-Ihsan Bandung Tahun 2023 adalah anak yang menggunakan 2 jenis gawai (46.7%) dengan gawai yang paling sering digunakan adalah televisi (100%) dan durasi penggunaan termasuk dalam kategori lama (>60 menit) (93.3%). Seluruh anak yang mengalami gangguan bahasa ekspresif di RSUD Al-Ihsan Bandung memiliki riwayat penggunaan gawai yang berlebihan. Semakin tingginya penggunaan gawai pada anak maka akan mempengaruhi perkembangan bahasa pada anak.
Karakteristik Pasien Diabetes Melitus Tipe 2 dengan Komplikasi Ulkus Diabetikum di Rumah Sakit Al-Ihsan Tahun 2022 Zuliana Marwati Octaviani; R. Anita Indriyanti; Meta Maulida Damayanti
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.12161

Abstract

Abstract. Diabetes mellitus (DM) has a high prevalence, both globally, nationally and in West Java Province. Until 2019, diabetes was the direct cause of 1.5 million deaths worldwide. The high number of DM patients increases the risk of DM complications, namely diabetic ulcers, which are chronic complications of diabetes mellitus. These diabetic ulcers are the main cause of limb amputation in diabetic patients. The purpose of this study was to determine the characteristics of type 2 DM patients with diabetic ulcer complications at Al-Ihsan Hospital in the period of 2022. This study used an observational descriptive method with a cross sectional research design of 98 patients with diabetes mellitus at Al-Ihsan Hospital in 2022. Data were taken from complete and legible medical records. After observation, the results showed that the characteristics of type 2 diabetes mellitus patients with diabetic foot ulcers at Al-Ihsan Hospital in 2022 were mostly female (66.3%), mostly aged 51-60 years (42.9%), and almost no one underwent amputation (93.75%). The most common complications experienced by patients were electrolyte imbalance (21.21%) and acute kidney injury (18.2%). The conclusion of this study is that the incidence of type 2 DM with diabetic ulcer complications is more common in women and attacks the 51-60 year old age group and there are not many patients who undergo amputation. Other complications that are most common in patients with type 2 DM with diabetic ulcers are electrolyte imbalance and acute kidney injury. Abstrak. Penyakit diabetes mellitus (DM) memiliki prevalensi yang cukup tinggi, baik secara global, nasional maupun di Provinsi Jawa Barat. Hingga tahun 2019, diabetes menjadi penyebab langsung dari 1,5 juta kematian di seluruh dunia. Tingginya jumlah penderita DM meningkatkan risiko kejadian komplikasi DM yaitu ulkus diabetikum yang merupakan komplikasi kronis dari diabetes melitus. Ulkus diabetikum ini adalah penyebab utama amputasi ekstremitas pada pasien diabetes. Tujuan dari penelitian ini adalah untuk mengetahui gambaran karakteristik penderita DM tipe 2 dengan komplikasi ulkus diabetikum di RSUD Al-Ihsan periode tahun 2022. Penelitian ini menggunakan metode observasional descriptive dengan desain penelitian cross sectional terhadap 98 orang pasien diabetes mellitus di Rumah Sakit Al Ihsan Tahun 2022. Data diambil dari rekam medis yang lengkap dan terbaca. Setelah dilakukan observasi, didapatkan hasil penelitian yang menyatakan bahwa karakteristik penderita diabetes tipe 2 penderita ulkus kaki diabetik di RS Al-Ihsan tahun 2022 sebagian besar berjenis kelamin perempuan (66,3%), sebagian besar berusia 51-60 tahun (42,9%), dan hampir tidak ada yang menjalani amputasi (93,75%). Komplikasi yang paling banyak dialami pasien adalah ketidakseimbangan elektrolit (21,21%) dan Cedera Ginjal Akut (18,2%). Kesimpulan dari penelitian ini adalah kejadian DM tipe 2 dengan komplikasi ulkus diabetikum lebih banyak terjadi pada perempuan dan menyerang kalangan usia 51-60 tahun serta yang menjalani tindak amputasi tidak banyak dilakukan. Komplikasi lainnya yang terbanyak pada penderita DM tipe 2 dengan ulkus diabetikum yaitu ketidakseimbangan elektrolit dan cedera ginjal akut.
Scoping Review: Pengaruh Farmakodinamik Gas Air Mata terhadap Pernapasan Manusia Ismu Huzen; R. Anita Indriyanti; Noormartany
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.12243

Abstract

Abstract. Tear gas is also called Riot control agent (RCA) is a non-lethal chemical warfare agent (CWA) that can quickly cause sensory irritation or physicalparalysis in humans. Pharmacodynamics in respiration occurs due to foreign objects (tear gas) entering the respiratory tract resulting in interactions between namino acids, ligands and receptors in the respiratory tract, thus creating biological events. The aim of this research is to determine the pharmacodynamic impact of tear gas on human breathing. The research method used is prism diagram. The samples used were tiga original research articles from international journals relating to the pharmacodynamic influence of tear gas on human breathing. Inclusion criteria include research articles that have been published in international journals and accessed from the Pubmed, ScienceDirect, Springerlink, Proquest, and Taylor and Francis databases. Keywords and queries. Exclusion criteria include discrepancies between the title, abstract, and conformity with Population, Intervention, Comparison, Outcome, Study (PICOS) criteria, articles that are duplicates with other databases, and articles that are paid for. Pharmacodynamics of tear gas affects human breathing and can cause several diseases such as lung, skin and eye injuries. The dangers of tear gas if it enters the respiratory tract include a stinging or burning sensation in the nose, tight chest, sore throat, coughing, dyspnea, bronchoconstriction accompanied by wheezing, difficulty breathing with acute and chronic pain, and can cause lung injury. Abstrak. Gas air mata yang juga disebut Riot control agent (RCA) merupakan salah satu non-letal chemical warfare agent (CWA) yang secara cepat dapat menyebabkan iritasi sensorik maupun melumpuhkan fisik pada manusia. Farmakodinamik pada pernapasan terjadi karena benda asing (gas air mata) yang masuk ke saluran pernapasan sehingga terjadi interaksi antara asam amino, ligan, dan reseptor yang berada di saluran pernapasan sehingga membuat kejadian biologi. Tujuan penelitian ini adalah mengetahui dampak farmakodinamik gas air mata terhadap pernapasan manusia. Metode penelitian yang digunakan adalah diagram PRISMA. Sampel yang digunakan adalah tiga artikel original research dari jurnal internasional yang berkaitan dengan pengaruh farmakodinamik gas air mata terhadap pernapasan manusia. Kriteria inklusi meliputi artikel penelitian yang telah terbit pada jurnal internasional dan diakses dari database Pubmed, ScienceDirect, Springerlink, Proquest, dan Taylor and Francis. Keywords dan query. Kriteria eksklusi meliputi ketidaksesuaian antara judul, abstrak, dan kesesuaian dengan kriteria Population, Intervention, Comparation, Outcome, Study (PICOS), artikel yang duplikasi dengan database lainnya, dan artikel yang berbayar. Farmakodinamik gas air mata berpengaruh terhadap pernapasan manusia dan dapat menyebabkan beberapa penyakit seperti cedera paru, kulit, dan mata. Bahaya gas air mata jika masuk ke dalam saluran pernapasan berupa sensasi menyengat atau terbakar di hidung, dada kencang, sakit tenggorokan, batuk, dispnea, bronkokonstriksi disertai mengi, kesulitan bernapas dengan nyeri akut dan kronis, serta dapat menyebabkan cedera paru.
Perbedaan Pola Bakteri pada Rongga Mulut Perokok dan Bukan Perokok Arsyi Alif Muhammad; R.Anita Indriyanti; Julia Hartati
Jurnal Riset Kedokteran Volume 4, No.2, Desember 2024, Jurnal Riset Kedokteran (JRK)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrk.v4i2.5009

Abstract

Abstract. Smoking contributes to higher mortality and morbidity worldwide than any other risk factor. Most side effects occur in the oral cavity, in the form of oral diseases that occur more frequently and treatment is less effective in smoking patients. This study aims to see differences in bacterial patterns in the oral cavity of smokers and non-smokers. This research is a comparative analytical observational study with the chi square test and a cross-sectional approach. The characteristics of the research subjects were that most were aged 21-30 years and most had smoked >10 years. The results of this study showed that more gram-negative and gram-positive bacteria were found in the oral cavities of smokers than in the oral cavities of non-smokers. From this study it can be concluded that there are differences in the pattern of Gram-positive rod bacteria between the two groups (p=0.034). The difference in bacterial patterns in smokers and non-smokers can be caused by the content of cigarettes, namely nicotine, which can weaken the immune system and cause narrowing of blood vessels, including those in the tissue around the teeth. From the results of this research, environmental disturbances caused by smoking can contribute to bacterial patterns in the oral cavity, which ultimately creates a favorable environment for the growth of bacteria that cause periodontal disease. Abstrak. Merokok berkontribusi terhadap mortalitas dan morbiditas yang lebih tinggi di seluruh dunia dibandingkan dengan faktor risiko lainnya. Efek samping paling banyak terjadi di rongga mulut, berupa penyakit mulut yang lebih sering terjadi dan pengobatan menjadi kurang efektif pada pasien perokok. Penelitian ini bertujuan untuk melihat perbedaan pola bakteri di rongga mulut pada perokok dan bukan perokok. Penelitian ini merupakan studi observasional analitik komparatif dengan uji chi square dan pendekatan potong lintang. Karakteristik subjek penelitian adalah sebagian besar berusia 21-30 tahun dan sebagian besar lama merokok >10 tahun. Hasil dari penelitian ini pada rongga mulut perokok lebih banyak ditemukan bakteri batang gram negatif dan batang gram positif dibandingkan pada rongga mulut bukan perokok. Dari penelitian ini dapat disimpulkan terdapat perbedaan pada pola bakteri batang gram positif antara kedua kelompok (p=0,034). Perbedaan pola bakteri pada perokok dan bukan perokok dapat disebabkan karena kandungan rokok yaitu nikotin yang dapat melemahkan sistem kekebalan tubuh dan menyebabkan penyempitan pembuluh darah, termasuk yang berada di jaringan sekitar gigi. Dari hasil penelitian ini gangguan lingkungan yang disebabkan merokok dapat berkontribusi terhadap pola bakteri pada rongga mulut, yang pada akhirnya menciptakan lingkungan yang menguntungkan bagi pertumbuhan bakteri penyebab penyakit periodontal.
Nuclear Changes Features in Buccal Mucosa Smear of Adult Male Smokers Using Pappaniculou Staining Kharisma, Yuktiana; Indriyanti, Raden Anita; Yuniarti, Lelly; Noormartany, Noormartany; Nur, Ismet Muchtar; Yenolinsky, Yolanda
Althea Medical Journal Vol 12, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n1.3486

Abstract

Background: Tobacco smoke contains a combination of chemicals that could be harmful to the buccal mucosa as the first part of the body that has been exposed. Damage to the buccal epithelial cells has the potential to become a malignant lesion. This study aimed to describe changes in the nuclear epithelial of the buccal mucosa using Pappaniculou staining as an indicator of mucosal damage in smokers.Methods: This was a descriptive analytical study, involving adult male participants from Bale Endah District, Bandung Regency, Indonesia aged >35 years, who had smoked for ≥10 years. Buccal mucosa smear was taken, and the features of nuclear epithelial changes were observed per 500 cells, each at 400x magnification with Pappaniculou stain to evaluate the features of micronucleus, broken egg, karyorrhexis, karyolysis. Those who did not smoke were recruited as a control group.Results: Smokers were mostly light active smokers or kretek cigarettes, with a smoking duration of ≥15 years. The frequency of micronucleus (p<0.001), broken eggs (p<0.001), karyorrhexis (p=0.001), karyolysis (p=0.003) in the buccal mucosal epithelial was significantly different between the smoker and non-smoker groups.Conclusions: All epithelial nuclear changes have shown significant differences between smoker and non-smoker groups. Nuclear epithelial features in smoker may be associated with future malignancies, therefore, smoking cessation programs are necessary to substantially reduce tobacco use, thus fostering a healthy lifestyle for everyone.
PEMBERDAYAAN ALUMNI FK UNISBA WILAYAH PRIANGAN TIMUR SEBAGAI UPAYA KONTRIBUSI PEDULI PESANTREN SEHAT DI LINGKUNGANNYA Indriyanti, Raden Anita; Perdana, Rizki; Widiyanti, Alvira
Jurnal Abdi Insani Vol 12 No 2 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i2.2241

Abstract

Based on a preliminary survey, situational analysis and dialogue conducted by the FK Unisba service team and alumni at the Sabilunnajat Islamic boarding school, produced data that the need for information regarding health, especially clean and healthy living behavior, is still minimal. Seeing the high potential for medical graduates from Islamic educational institutions , it is appropriate to make various efforts by FK Unisba alumni to solve health problems in Islamic boarding schools. The aim of this activity is to make efforts to empower FK Unisba Alumni in improving the health of students at the Sabilunnajat Islamic boarding school through training healthy student cadres. The method of this activity consists of a preparatory stage in form of a Focused Group Discussion by FK UNISBA alumni to identify problems in the Islamic boarding school environment, followed by an implementation stage through health screening and therapy, provision of health facilities, counseling for santri and training for healthy santri cadres. The activity ended with the reporting stage to assess the success of the training of healthy santri cadres. The results of this PKM activity are a reduction in health problems, the availability of health facilities, and the formation of  health cadres  as an effort to overcome early stage health problems in the Sabilunnajat Islamic boarding school environment. The importance of the role of partnership and cooperation between various parties, especially the Islamic boarding school comittee, the UNISBA Medical Faculty, the contribution of alumni and authorities in policy making, is the key to the success in improving the level of health in the surrounding environment.
Pendampingan kewaspadaan bencana alam longsor dan antisipasinya di Pesantren Sabilunnajat kecamatan Rancah kabupaten Ciamis Raden Anita Indriyanti; Yani Triyani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 1 (2024): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i1.22259

Abstract

AbstrakBencana alam longsor kabupaten Ciamis pada tahun 2021 mengakibatkan kerusakan asrama putra di pesantren Sabilunnajat. Berdasarkan hasil survey di pesantren Sabilunnajat, belum pernah ada pelatihan kewaspadaan terhadap bencana longsor di pesantren tersebut. Kegiatan pengabdian ini bertujuan memberikan solusi menjadikan kader santri siaga bencana, melalui pelatihan perwakilan santri sebagai kader kesehatan sesuai bimbingan BNPB dengan kolaborasi tim dokter yang tergabung dalam ikatan alumni FK Unisba. Metode yang dilakukan pada tahap awal adalah melakukan edukasi berupa sosialisasi kewaspadaan bencana alam longsor, dan perilaku hidup bersih dan sehat (PHBS) , selanjutnya pembentukan kader santri siaga bencana, serta pembentukan Pos Kesehatan Pesantren berkolaborasi dengan dokter alumni FK Unisba. Kegiatan dilakukan di Pesantren Sabilunnajat-Ciamis, bulan Juni–Agustus 2023. Hasil dari program pengabdian ini adalah didapatkan hasil secara statistik yang meningkat signifikan setelah pemberian penyuluhan, terbentuknya kader pesantren sehat, pembentukan sarana dan prasarana kamar mandi di lokasi aman longsor, berjalannya fasilitasi pelayanan kesehatan gratis melalui kerjasama dengan klinik dikelola oleh alumni Fakultas Kedokteran Unisba. Kata kunci: dokter alumni FK Unisba; kader santri; siaga bencana AbstractThe natural landslide disaster in Ciamis district in 2021 resulted in damage to the boys' dormitory at the Sabilunnajat Islamic boarding school. Based on the results of a survey at the Sabilunnajat Islamic boarding school, there has never been any landslide awareness training at the Islamic boarding school. This service activity aims to provide a solution to make students prepared for disasters through training student representatives as health cadres according to BNPB guidance with the collaboration of a team of doctors who are members of the FK Unisba alumni association. The method used in the initial stage was to provide education in the form of socializing awareness of landslide disasters, and clean and healthy living behavior (PHBS), followed by the formation of santri health cadres, as well as the establishment of Islamic boarding school health posts in collaboration with FK Unisba alumni doctors. Activities were carried out at the Sabilunnajat-Ciamis Islamic boarding school, June–August 2023. The results of this service program were that statistically significant results  increased after providing counseling, the formation of healthy Islamic boarding school cadres, the establishment of bathroom facilities and infrastructure in landslide-safe locations, and ongoing facilitation. free health services in collaboration with clinics managed by alumni of the Unisba Faculty of Medicine. Keywords: FK Unisba alumni doctors, student cadres, disaster preparedness.
Mango-Lime Peel Nanoparticles Improve Diabetic Parameters, Lipid Profiles and Pancreatic Cell Damage in Cigarette Smoke-Exposed Diabetic Rats Yuktiana Kharisma; Raden Anita Indriyanti; Meta Maulida Damayanti; Lelly Yuniarti; Yuke Andriane; Ratih Syifa Hanifah; Saphiera Damayanti
The Indonesian Biomedical Journal Vol 18, No 4 (2026)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v18i4.4220

Abstract

BACKGROUND: Diabetes mellitus often exacerbated by cigarette smoke, which disrupts glucose homeostasis and lipid metabolism. Mango (Mangifera indica L.) and lime (Citrus amblycarpa) peels contain various phytochemical compounds, including those are reported to have metabolic and cytoprotective properties, but their combined nanoparticle formulation in cigarette smoke-exposed diabetes cases remains unexplored. Therefore, this study was conducted to evaluate the synergistic effect of mango-lime peel nanoparticles (NanoMC) on glycemic control, lipid profiles, and pancreatic cell damage in cigarette smoke-exposed diabetic rats.METHODS: Mango and lime peel ethanol extract was prepared into nanoparticles using emulsion-solvent evaporation method and followed by sonication and homogenization, and subsequently divided into three concentration groups. Rats were diabetic-induced and smoke-exposed, before being treated with/without Simvastatin + Glibenclamide, 20, 40, or 80 mg/kgBW NanoMC. Parameters including blood glucose, insulin, homeostatic model assessment of insulin resistance (HOMA-IR), homeostatic model assessment of beta-cell function (HOMA-β), hemoglobin A1c (HbA1c), and lipid profiles were then measured. To evaluate pancreatic cell damage, the pancreatic tissue was collected, fixed, and then evaluated by using Hematoxylin and Eosin (H&E) staining.RESULTS: NanoMC administration significantly reduced blood glucose, HbA1c, triglycerides, cholesterol, and low-density lipoprotein (LDL) levels (p<0.05). NanoMC treatment also increased insulin levels, HOMA-β, and high-density lipoprotein (HDL). After the treatment with NanoMC, particularly with 80 mg/kgBW concentration, fewer degenerative and necrotic cells were found compared to the other groups, showing its ability to attenuate pancreatic cell damage.CONCLUSION: The combination of NanoMC could improve glycemic status, modulate lipid profiles, and improved pancreatic cell damage in diabetic rats exposed to cigarette smoke.KEYWORDS: Mangifera indica, Citrus amblycarpa, nanoparticles, diabetes mellitus, cigarette smoke, lipid profiles, pancreatic histopathology
Co-Authors A. W. Soekandar Abdul Haris Maulana Agista Rohani Almayda Maharani Patoni Andriane, Yuke Arief Budi Yulianti Arsyi Alif Muhammad Eka Hendryanny Fajar Awalia Yulianto Ismet Muchtar Nur Ismu Huzen Julia Hartati Lelly Yuniarti Luthfi Rahinajati M. Sujatno Maya Tejasari Mayka Adisti Yunus Meike Rachmawati Meta Maulida Damayanti Miranti Kania Dewi Noormartany Perdana, Rizki Rahmi Fathonah Rahmi Fathonah, Rahmi Ratih Syifa Hanifah Ratna Damailia RB. Soeharman Herdiningrat Sadeli Masria Saphiera Damayanti Uci Ari Lantika Widiyanti, Alvira Wiwit Kesumaningrum Yani Triyani Yenolinsky, Yolanda Yuke Andriane Yuktiana Kharisma Zuliana Marwati Octaviani