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Analysis of the Effectiveness of Antihypertensive Drugs on Blood Pressure Reduction in Patients Receiving Calcium Channel Blocker and Angiotensin Receptor Blocker Therapy Fauziah; Reina Meilani; Zahra Amalia Ristiana; Khamdiyah Indah Kurniasih; Amelia Sari; Nurmalia Zakaria
Viva Medika Vol 19 No 2 (2026)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v19i2.2088

Abstract

This study aimed to analyze the effectiveness of antihypertensive drugs from the Calcium Channel Blocker (CCB) and Angiotensin Receptor Blocker (ARB) classes in reducing blood pressure among hypertensive patients. The study employed a retrospective observational design using medical record data collected from November 2024 to February 2025 and was conducted in four primary healthcare centers in Banyumas Regency. A total of 70 patients enrolled in the PROLANIS program were selected using purposive sampling. Data were analyzed based on changes in blood pressure and statistically tested using the One-Way ANOVA test. The results showed that the ARB + CCB combination therapy was the most frequently used regimen (50%) and achieved the lowest mean blood pressure value (129.94/77.25 mmHg) among the therapy groups. Statistical analysis indicated a significant difference in systolic and diastolic blood pressure between patients receiving monotherapy and combination therapy (p < 0.05). These findings suggest that the ARB + CCB combination therapy was associated with greater blood pressure reduction compared to monotherapy among hypertensive patients in primary healthcare settings.
The Relationship Between Adherence to Taking Medication with the Level of Knowledge and Family Support in TB Patients at Kroya Health Centre, Cilacap Regency Hidayat Sugeng Riyadi; Fauziah; Silma Kaaffah
Viva Medika Vol 17 No 3 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1604

Abstract

TB (Tuberculosis) patients in Indonesia are the 2nd highest in the world after India. The large number of TB patients in Indonesia is due to the lack of success in TB treatment due to patient non-compliance with medication regularly. Factors that affect non-compliance are low knowledge of TB patients and lack of family support. This study aims to determine the level of family knowledge and support, medication adherence, and determine the relationship between the level of knowledge and family support to medication adherence in TB patients at the Kroya Health Center, Cilacap Regency in 2024. This study uses a non-experimental method with cross-sectional data collection conducted in April-May 2024. The study population is all TB patients totaling 130 respondents who underwent treatment at the Kroya Health Center, Cilacap Regency from November 2023 to May 2024, and the research sample was 56 respondents. The conclusion of this study is that the knowledge level of TB respondents is the highest at 37.5% and 55.4%, and the adherence to taking medication at the Kroya Health Center is 30.4% and 57.1%. In this study, the highest TB patients were at a moderate level of knowledge (55.4%); family support is not supportive (96.4%) and medication adherence is low (30.4%) to moderate (57.1%). Testing with the chi-square method there was a relationship between the level of knowledge and medication adherence in TB patients (p-value 0.000), but there was no relationship between family support and medication adherence (p-value 0.268) in patients at the Kroya Health Center, Cilacap Regency with a r value of 0.541. The limitation of this study is that there is no follow-up on the respondents such as monitoring TB drugs so that the existing data is only data taken when filling out the questionnaire.
Analisis Determinan Perilaku Kepatuhan Pengobatan Pasien Diabetes Mellitus Tipe 2 Lanjut Usia Di Puskesmas Kembaran 1 Nozza Fauzan Khuriyathusyfah; Silma Kaaffah; Fauziah
Health & Medical Sciences Vol. 3 No. 4 (2026): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v3i4.775

Abstract

Medication adherence is a crucial factor in the successful management of type 2 diabetes mellitus (T2DM), particularly among older adults who are more vulnerable to treatment failure due to age-related physiological decline and multiple comorbidities. This study aimed to determine the level of medication adherence and analyze the factors associated with medication adherence behavior among older adults with type 2 diabetes mellitus at Kembaran 1 Primary Health Center. This quantitative study employed a cross-sectional design involving 62 older adults with type 2 diabetes mellitus selected using a total sampling technique. Medication adherence was assessed using the Medication Adherence Rating Scale-10 (MARS-10), while the associations between variables were analyzed using the Chi-square test. The results showed that 64.5% of the respondents had a high level of medication adherence, whereas 35.5% demonstrated low adherence. Bivariate analysis revealed that age (p = 0.008), educational level (p = 0.021), employment status (p = 0.013), body mass index (BMI) (p = 0.015), and type of antidiabetic therapy (p = 0.001) were significantly associated with medication adherence behavior. In contrast, sex (p = 0.675), duration of diabetes mellitus (p = 0.510), and the presence of comorbidities (p = 0.519) were not significantly associated with medication adherence. These findings indicate that medication adherence among older adults with type 2 diabetes mellitus is influenced by sociodemographic factors, clinical characteristics, and treatment-related factors. Identifying these determinants may serve as a basis for developing intervention strategies to improve medication adherence and optimize therapeutic outcomes.
Evaluasi Pengelolaan Obat di Apotek Berkah Waras Mipiran Purbalingga Esanda Falentine Milani; Fauziah; Siti Setianingsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2555

Abstract

Pharmacies are easily accessible health facilities and serve as practice locations for pharmacists in supporting public health. Pharmacy services must ensure the availability of safe, high-quality, effective, and affordable medicines and medical devices. Proper drug management is therefore essential to maintain the continuity and quality of pharmaceutical services. This study aimed to determine whether the drug management system at Berkah Waras Pharmacy complies with the Minister of Health Regulation No. 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies. The study also aimed to assess the effectiveness and efficiency of the drug management system in ensuring medicine availability. A quantitative descriptive design was employed, using observations and interviews as data collection methods. The study was conducted from February to April at Berkah Waras Pharmacy, Mipiran, Purbalingga. The results showed that the overall drug management system achieved 59% compliance. Planning was the best-performing aspect, with 100% compliance, while recording and reporting achieved only 33%, and destruction and withdrawal achieved 0%. These findings indicate that drug management at Berkah Waras Pharmacy did not fully comply with the applicable standards. The main obstacles were related to recording drug mutations and the absence of physical stock cards.
Analysis of the Relationship Between Knowledge Level and Whitening Cosmetic Selection Behavior Among University Students in Banyumas Widiya Rizky Shopa Utami; Khamdiyah Indah Kurniasih; Siti Setianingsih; Fauziah
Jurnal Kesehatan Akimal Vol 5 No 2 (2026): EDISI OKTOBER 2026
Publisher : Akademi Keperawatan Kesdam Iskandar Muda Lhokseumawe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58435/jka.v5i2.269

Abstract

Background: The increasing use of skin-lightening cosmetics has made product safety and informed selection important concerns among university students. Adequate knowledge is essential to help students recognize cosmetic ingredients, understand potential risks, and make responsible purchasing decisions. Objective: This study aimed to assess students’ knowledge and behavior in selecting skin-lightening cosmetics, examine the relationship between knowledge and selection behavior, and determine the association of educational type and level with cosmetic selection behavior among university students in Banyumas Regency. Methods: A descriptive-analytical study with a cross-sectional design was conducted in January 2025. Data were collected through an online questionnaire using Google Forms from 400 university students recruited through random sampling. Data were analyzed using Jamovi, with statistical tests applied to examine the relationships between knowledge, cosmetic selection behavior, and educational characteristics. Results: The findings showed that 71% of respondents had a high level of knowledge, while 91% demonstrated good behavior in selecting skin-lightening cosmetics. Knowledge was strongly and positively associated with selection behavior (p < 0.01; Spearman’s rho = 0.640). However, educational type and educational level were not significantly associated with cosmetic selection behavior (p > 0.05 and p = 0.701, respectively). Conclusion: Most students demonstrated good knowledge and behavior in selecting skin-lightening cosmetics. Higher knowledge levels were significantly associated with better selection behavior, whereas educational type and level showed no significant association. These findings highlight the importance of strengthening knowledge and awareness of cosmetic safety to encourage informed and responsible product selection among university students.