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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kesehatan Masyarakat Indonesia Journal of Agromedicine and Medical Sciences UNEJ e-Proceeding Jurnal Keperawatan Padjadjaran Al-sihah: The Public Health Science Journal Jurnal Respirologi Indonesia Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Health Sains
Adelia Handoko
Fakultas Kedokteran Universitas Jember
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Effectiveness of Vitamin C Administration on Outcome in COVID-19 Patients: A Systematic Review and Meta-Analysis Desie Dwi Wisudanti; Nur Lintang Nabilah Sri Kusumasari; Adelia Handoko; Cholis Abrori; Angga Mardro Raharjo
Jurnal Respirologi Indonesia Vol 43, No 2 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i2.341

Abstract

Background: Numerous studies on the effectiveness of vitamin C against the COVID-19 infection have been widely carried out recently. However, the differences in dosage ranges and therapeutic efficacy in previous studies have prompted a systematic literature review on the effectiveness of vitamin C on outcomes in COVID-19 patients. In addition, this study aimed to determine the appropriate therapeutic dose of vitamin C for COVID-19 patients, either alone or in combination with other supplements, and to determine the side effects.Methods: Gleaned from the search on Pubmed, Science Direct, and Google Scholar databases up to April 25, 2022, fourteen studies were relevant, namely five studies using vitamin C orally and nine studies administered intravenously. We assessed multiple outcomes, including mortality, hospitalization, and symptoms. The quality and risk of bias analyses were performed using JBI critical appraisal tools.Results: The oral administration of vitamin C resulted in a significant difference in the mortality of COVID-19 patients (OR=0.66; 95% CI=0.45–0.97; P=0.04; I2=0%) and a non-significant difference in the outcome. Duration of hospitalization (OR = -0.21; 95% CI = -2.70-2.28; P=0.87; I2=94%). Regarding the cost-effectiveness and side effects manifested in digestive disorders such as nausea, diarrhea, stomach cramps, and vomiting, vitamin C with a dose of 500-1000 mg could be given orally.Conclusion: Oral administration of vitamin C showed a reduction in the mortality of asymptomatic COVID-19 patients with moderate symptoms.
Correlation between Platelets Count and C-reactive Protein in COVID-19 Patient in Jember Regency Rini Riyanti; Faliqul Bahar Muhammad; Adelia Handoko
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 2 (2023)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i2.2002

Abstract

The laboratory test for Coronavirus disease 2019 (COVID-19) is very important for initial treatment and predicting the prognosis of the patients, but there have been reports of false negative COVID-19 diagnostic test results. Another study reported changes in COVID-19 patient biomarkers, namely platelets count and C-Reactive Protein (CRP) levels. This study investigated the correlation between platelet count and CRP in COVID-19 patients. This study was conducted using a cross-sectional analytic observational method, through secondary data analysis of COVID-19 patients who hospitalized between June – August 2021 at Dr. Soebandi Hospital and Jember Klinik Hospital. Of 30 patients, there were 16 male patients (53%) and 14 female patients (47%); 18 patients in the 46-59 years old age group (60%) and 12 patients in ≤ 4 years old (40%) age group; and there were 8 patients admitted to ICU (26.67%). There was a negative correlation between platelet count and CRP in COVID-19 patients (r = -0.733; p<0.001). A strong correlation between platelet count and CRP is related to prognostic and predictive factors of severity in COVID-19 patients. Further studies about the analysis of other biomarkers in COVID-19 are needed to obtain more prognostic and predictive factors of severity in patient.
Anesthetic Management in Cerebellopontine Angle Tumor (CPA) Removal Patients Adelia Handoko; Taufiq Gemawan; Rizal Hadi Pratama; Renaldi Wibisono
Jurnal Health Sains Vol. 4 No. 6 (2023): Journal Health Sains
Publisher : Syntax Corporation Indonesia

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Abstract

Introduction : Cerebellopontine Angle Tumor (CPA) is the most common type of tumor found in the posterior fossa. Without a proper anesthetic approach, this can increase the risk of brain edema and hemorrhage due to surgical manipulation. Case Illustration : A 46-year-old woman was diagnosed with a meningioma type CPA tumor, CT-Scan found meningioma in the left petrous tentorial tubercullum sellae with perifocal edema in the pons and left cerebellum. The patient was planned to get tumor excision surgery in a supine position. General anesthesia was performed, induced using propofol, fentanyl and rocuronium. The patient had a good hemodynamic profile while in the ICU postopertively. Discussion : Proper patient positioning during CPA tumor surgery is one of the important factors in the success or failure of the procedure. TIVA technique uses propofol and fentanyl, can reduce CBF reduce intracranial pressure, maintain brain perfusion pressure and reduce CMRO2 to protect brain tissue from damage.Conclusion : Several things that must be evaluated routinely in these patients are maintaining hemodynamic stability by maintaining adequate cerebral perfusion pressure, reducing cerebral blood flow, maintaining normal autoregulation, reducing the rate of cerebral metabolic oxygen, and maintaining an adequate cerebral oxygen supply.
Management of General Anesthesia in Difficult Airway: A Case Report Taufiq Gemawan; Adelia Handoko; Muhammad Irsyad Amien; Nurrul Izza Misturiansyah; Muhamad Rizal Hadi Pratama
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.41778

Abstract

When dealing with clinical disorders known as difficult airways, airway management during general anesthesia still presents challenges. A cross-sectional study done in Indonesia in 2016 found that 28 out of 250 patients receiving general anesthesia had respiratory problems. The existing algorithm must be properly and effectively managed in order to resolve this issue. This case report discusses a 14-month-old pediatric patient with right preauricular lymphoma who will undergo tumor biopsy surgery using general anesthesia. The size of the tumor mass that has grown and covered the patient's airway makes it difficult to manage the airway during general anesthesia, making intubation impossible. To overcome this, bagging was carried out by improvising the technique of reversing the position of the mask cover on the patient during the operation. The patient can be saved and allowed to go home after treatment. Appropriate management during perioperative especially related to airway management will produce good results for patient health and safety. With this case report, hopefully it can add knowledge and an alternative ventilation technique if you encounter a similar case. Keywords: difficult airway, general anesthesia, lymphoma preauricular
Personal factors related to self-care management among people with hypertension at primary health care: A cross-sectional study Anggraini Dwi Kurnia; Sri Hariyati; Nur Melizza; Chairul Huda Al Husna; Anchaleeporn Amatayakul; Adelia Handoko
Jurnal Keperawatan Padjadjaran Vol. 11 No. 3 (2023): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v11i3.2340

Abstract

Background: Hypertension requires long-term treatment and can last a lifetime. Recommendations for hypertensive patients, where it is necessary to change behavior related to self-care, consist of increasing a healthy diet, limiting sodium intake, increasing physical activity, reducing smoking, and reducing alcohol consumption. Objective: The purpose of this study was to identify the self-care model of patients with hypertension in primary healthcare in Kota Malang. Methods: This study's design was descriptive analytic with a cross-sectional methodology. Using G Power, 321 hypertension patients were used as samples. Purposive sampling was used in this study. The instruments used H-SCALE, also known as the Hypertension Self-Care Activity Level Effects. Pearson Chi-squared test was used to examine correlations among variables. Results: Factors of gender (p=0.001) and education (p=0.020) are related to self-care in hypertensive patients. Majority of respondents were women, 223 people (69.5%), Most of the respondents had elementary school education, 136 people (41.4%), the majority of the 321 respondents (216, 67.3%) have moderate self-care category. Gender and age were significant factors associated with self-care among hypertensive patients (p<0.05)  Conclusion: Gender and education level have significant correlation with self-care management of hypertension. Providing self-management intervention by considering gender and education level needs improvement. Other factors need to be explored in  further research.
Co-Authors Al Munawir Alif Kufari Anchaleeporn Amatayakul Angga Mardro Raharjo Angga Mardro Raharjo Anggraini Dwi Kurnia Aprilia Tiyan Fatmawati Arifa Mustika Aris Prasetyo Bambang Purwanto Cahyo Bagaskoro Chairul Huda Al Husna Cholis Abrori Desie Dwi Wisudanti Eprila Darma Sari Faliqul Bahar Muhammad Farmarida Dika Rufaida Irawan Fajar Kusuma Jauhar Firdaus Karisma Adya Pertiwi Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana Lida Hutami Putri Luluk Mauludyahwati M. Ali Shodikin Muhamad Rizal Hadi Pratama Muhammad Irsyad Amien Nur Lintang Nabilah Sri Kusumasari Nur Melizza Nurrul Izza Misturiansyah Pipiet Wulandari Prasetyo, Aris Putri Prameswari Nastiti Ayu Renaldi Wibisono Rini Riyanti Rizal Hadi Pratama Roan Pratama Putra Sarwendah Siswi Winasis Saski Yasmin Alfina septa surya wahyudi, septa surya Sri Hariyati Taufiq Gemawan Taufiq Gemawan Taufiq Gemawan Ulfa Elfiah Waskito Setiaji