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All Journal Humaniora Lensa: Kajian Kebahasaan, Kesusastraan, dan Budaya MEDIA MEDIKA INDONESIANA Jurnal Anestesi Perioperatif Folia Medica Indonesiana Journal of Agromedicine and Medical Sciences Biomedika Briliant: Jurnal Riset dan Konseptual Journal of Medicine and Health Care : Jurnal Ilmiah Ilmu Kesehatan Oto Rhino Laryngologica Indonesiana Lembaran Sejarah Majalah Biomorfologi (Biomorphology Journal) Jurnal Riset Akuntansi dan Manajemen Malahayati (JRAMM) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology Masyarakat Indonesia PROFESSIONAL HEALTH JOURNAL Journal Philosophy of Law Journal of Medicine and Health
Bambang Purwanto
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Religion Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Qualitative Analysis of Cinnamomum burmannii Content using GCMS (Gas Chromatography Mass Spectometry) Method Hayati; Jusak Nugraha; Bambang Purwanto; Hari Basuki Notobroto; Yoes Prijatna Dachlan; Hari Setiono; Idha Kusumawati
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17556

Abstract

To identify the bioactive compounds in Cinnamomum burmannii and their biological activity. Cinnamonbark originating from Batu Malang, East Java, which was located 700-1300 meters above sea level, wasprocessed into dry extract by maceration method with 96% ethanol solvent. Furthermore, cinnamonethanol extract was analyzed using the GCMS method to look at the content of the bioactive componentfor further testing biological activity with the server Way2Drug PASS. GCMS results showed 40 activecompounds such as trans-cinnamaldehyde, trans-anethole, cinnamyl acetate, calacorene, cadina-1,4-diene, delta-cadinene. Furthermore, of the 40 compounds, the biological activity potential was testedfor 29 bioactive compounds based on PA (probable to be active) values predicted by the Way2DrugPASS server. Cinnamomum was tested against the potential as anti-fungi, anti-bacterial, anti-oxidant,anti-inflammatory, anti-diabetic, anti-neoplastic. Trans-cinnamaldehyde showed PA 0,583 as antiinflammatory, L-limonene PA0,818 as anti neoplastic, Tans-anethole PA 0,614 as anti neoplastic,Cinnamyl acetate PA 0,669 as anti inflammatory, calacorene PA 0,698 as anti inflammatory, DeltacadinenePA 0,651 as anti neoplastic, , Cathechin PA 0,828 as anti oxidant, alpha.-Cubebene PA 0,888 asanti inflammatory and PA 0,837 as anti neoplastic, melilotin PA 0,929 as anti neoplastic, CaryophyllenePA0,915 as anti neoplastic. Cinnamomum burmannii had biological potency based on potential activity(PA) 0,432 (+0,117) as antifungi, PA 0,335 (+0,090) as antibacterial, PA 0,304 (+0,199) as antioxidan,PA 0,561 (+0,190) as anti inflammatory, PA 0,373 (+0,170) as antidiabetic, PA 0,584 (+0,234) asantineoplastic.
The Effectiveness of Family Support Program based on Clean and Healthy Behaviour (CLHB) Indicators Rochana Ruliyandari; Bambang Purwanto; AA Subiyanto; Suwarto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17626

Abstract

A clean and healthy lifestyle behavior (CHLB) in the household structure is essential to maintain and improve the health of family members. However, in its implementation, consistency is needed so that clean and healthy lifestyle behavior can be carried out optimally based on ten indicators of a CHLB of household arrangements that the government has set. Therefore, this research was conducted using a cross-sectional design with a quantitative descriptive study design—population in the sub-district of Banguntapan, Bantul District, consisting of 826 households. The sample of this study was collected using a technique with a random sampling sample of 100 families and data collection using primary data and secondary data, and field observations. Based on the ten indicators of a clean and healthy lifestyle in the household structure, four indicators have not been appropriately implemented, namely giving exclusive breastfeeding (21%), weighing babies and toddlers every month (14%), doing physical activities every day (34%), and not smoking in the home (23%), with clean and healthy lifestyle coverage in the excellent category (66%). Therefore, it can be concluded that the application of a clean and healthy lifestyle in the Banguntapan, Bantul, household characteristics is good (66%) but has not met the government’s target because four indicators of a clean and healthy lifestyle have not been implemented optimally.
Comparison of the Effect of Glycemic Control on the Incidence of Fetal Macrosomia and Large for Gestational Age in Gestational Diabetes Mellitus Patients; A Systematic Review Natasha Tiara Bernadette; Budi Prasetyo; Sony Wibisono; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17972

Abstract

Background: Gestational diabetes mellitus (GDM) can be managed with blood glucose control management, which includes a healthy lifestyle, insulin therapy, and oral anti-diabetic drug (OAD) medications when needed. Sub-optimally or poorly managed GD Mmay lead to arisk of complications, one of which is an abnormal growth in the fetus. This study aimed to compare the effect of blood glucose control management on the incidence of fetal macrosomia and large for gestational age (LGA) births in patients with GDM. Methods: This systematic review study obtained data from formerly published studies from the Science Direct database. The article search method used the characteristics of PICO (Population, Intervention, Comparison, Outcome) and compiled using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. Conclusion: The use of medical nutrition therapy (MNT) and exercise in the therapeutic regimen, as well as routine monitoring of glycemic levels are very important to control the patient’s glycemic level. The use of metformin can increase the success of therapy due to reduced levels of LGA and macrosomia in GDM patients
Perbandingan Efektivitas Mindfulness Based Intervention Terhadap Diabetes Resilience Training Pada Diabetes burnout Syndrome Dan Kontrol Glikemik Penderita Diabetes Melitus Tipe 2: A Systematic Review Made Dian Kusumawati; Kusnanto Kusnanto; Bambang Purwanto
BRILIANT: Jurnal Riset dan Konseptual Vol 6 No 4 (2021): Volume 6 Nomor 4, November 2021
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.061 KB) | DOI: 10.28926/briliant.v6i4.759

Abstract

Diabetes burnout merupakan tantangan utama dalam pengelolaan Diabetes melitus. Hal ini berdampak pada tidak terkontrolnya gula darah pasien, yang berakhir dengan peningkatan angka kematian disebabkan oleh komplikasi Diabetes. Tujuan penelitian ini adalah untuk membandingkan efektivitas intervensi berbasis mindfulness dengan diabetes resilience training terhadap diabetes burnout dan kontrol glikemik penderita DMT2. Metode: delapan database dicari secara sistematis meliputi: Scopus, ProQuest, PubMed, Science Direct, EBSCO, SINTA, Springer Link, dan Google Scholars, menggunakan Randomized Controlled Trial atau desain kuasi eksperimen, diterbitkan antara tahun 2011-2021 dengan kombinasi 6 kelompok kata kunci dalam bahasa Inggris dan bahasa Indonesia. The Joanna Briggs Institute Guideline digunakan untuk menilai kualitas studi, sedangkan PRISMA checklist digunakan sebagai panduan dalam membuat review. Kesimpulan: kedua intervensi efektif dalam menurunkan burnout akibat diabetes. Namun, diabetes resilience training lebih efektif jika diberikan pada kondisi awal diabetes karena pengetahuan yang diperoleh akan membantu responden untuk menyadari manajemen diri dan kontrol glikemiknya lebih dini.
Analisis Syndecan-1 Laktat dan Profil Lipid Sebagai Faktor Risiko Keparahan dan Mortalitas Sepsis Yopie Wiguna; Philia Setiawan; Bambang Pujo Semedi; Bambang Purwanto
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2251

Abstract

Pada sepsis, endothelial glycocalyx (EG), dapat rusak dan luruh melepaskan syndecan-1 ke dalam plasma. Kerusakan EG akan mengganggu mikrosirkulasi, menimbulkan hipoperfusi jaringan, dan meningkatkan kadar laktat. Gangguan profil lipid pada sepsis terjadi karena gangguan metabolisme dan kerusakan langsung hepatosit akibat meluruhnya EG. Penelitian ini bermaksud menganalisis syndecan-1, laktat, dan profil lipid sebagai faktor risiko keparahan dan mortalitas pada pasien sepsis. Penelitian ini adalah penelitian analitik observasional pada 39 pasien dewasa yang memenuhi kritera sepsis-3. Keparahan sepsis diklasifikasikan menjadi sepsis dan syok septik dan ditentukan dalam 6 jam setelah time zero berdasarkan penggunaan vasopresor, kecukupan resusitasi cairan, dan nilai laktat ulangan. Kematian 7 hari dihitung sejak time zero sepsis. Syndecan-1, laktat, dan profil lipid diambil dalam jam pertama setelah time zero dianalisis sebagai faktor risiko keparahan dan mortalitas 7 hari. Analisis data dilakukan dengan uji logistik regresi bivariat dan multivariat. Pada penelitian ini didapatkan 20 pasien dengan sepsis, 19 pasien dengan syok septik. Berdasar atas mortalitas 7 hari, 10 pasien meninggal dan 29 pasien bertahan hidup. Laktat dan syndecan-1 merupakan prediktor keparahan pada sepsis. Laktat merupakan variabel yang lebih superior dibanding dengan syndecan-1 sebagai prediktor keparahan sepsis. Laktat merupakan prediktor untuk mortalitas 7 hari pada pasien sepsis. Simpulan penelitian ini adalah laktat dan syndecan-1 merupakan prediktor keparahan pada sepsis. Laktat merupakan prediktor kematian 7 hari pada sepsis. Syndecan-1 Lactate and Lipid Profiles as Risk Factors for Severity and Mortality in SepsisIn sepsis, endothelial glycocalyx (EG) may experience damages and decay, releasing syndecan-1 into plasma. EG damages will disrupt microcirculation, causing tissue hypoperfusion and increasing lactate levels. Disorders of the lipid profile in sepsis occur due to metabolic disorders and direct hepatocyte damages due to EG shedding. This study intended to analyze the Syndecan-1, lactate, and lipid profiles as risk factors for severity and mortality in septic patients. This was an observational analytic study on 39 adult patients who met the criteria for sepsis-3. Sepsis severity was classified into sepsis and septic shock and was determined within 6 hours after time zero based on the vasopressor use, adequacy of fluid resuscitation, and repeat lactate values. The 7-day mortality was counted from time zero sepsis. Syndecan-1, Lactate, and Lipid Profiles were assessed within the first hour after time zero and analyzed as risk factors for severity and 7-day mortality. Data analysis was performed using bivariate and multivariate logistic regression tests. In this study, there were 20 patients with sepsis, 19 patients with septic shock. Based on the 7-day mortality, 10 patients died and 29 patients survived. Lactate and Syndecan-1 are predictors of severity in sepsis. Lactate is superior than Syndecan-1 as a predictor of sepsis severity and is a predictor of 7-day mortality in septic patients. Nonetheless, both lactate and Syndecan-1 are predictors of severity in sepsis.
Environmental Conditions and Sincerity affects Cortisol and ?-Endorphins Plasma Levels in Young Healthy Subjects Undergoing Dawood’s Fast Indri Ngesti Rahayu; Bambang Purwanto; Moh. Ali Azis; M. Yogiarto; Aryati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14761

Abstract

Background: Prevention of Coronary Heart Disease by identifying risk factors facilitates the planning ofprevention interventions. The prevalence of non-communicable disease (NCD) increases with one of therisk factors for NCD being an unbalanced diet. Dawood’s fasting is one of the sunnah fastings that can bedone at any time except at times that are forbidden to fast. This fast is a combination model of TRF and ADF(modified ADF = MADF).Objective: To prove that MADF for six consecutive weeks can increase levels of the hormone ?-endorphinsand reduce levels of the hormone cortisol in peripheral blood circulation.Materials and Methods: Quasi-experimental research with a comparative design of a non-equivalentcontrol group with a population of PP students. Hidayatullah Surabaya with the purposive sampling methoduntil the number of samples required was met as many as 34 people and divided into two groups, namelycontrol and MADF treatment for six consecutive weeks. Sampling was carried out at the pre-test, at the endof the third week for the middle and at the post-test. All subjects in both groups received the same nutritiontwice a day for 42 days. The subject gets spiritual motivation from competent resource persons to givespiritual spark twice.Result: Dawood’s fasting (MADF) for six consecutive weeks did not cause significant differences comparedto control on cortisol and ?-endorphins (p> 0.05). However, Dawood’s fasting (MADF) for six consecutiveweeks decreased the mean values of cortisol levels due to the effect of fasting, although there was also asignificant difference in the control group. Meanwhile the ?-endorphins mean values was increased at themiddle of study, and then decreased at the end of the study, with a significant difference in the both groupbefore and after treatment.Conclusion: There was no difference in cortisol and ?-endorphins levels in healthy young adult subjectsundergoing Dawood’s fast due to the influence of the same environmental conditions and a change in thesincerity of the subjects.
Clinical Finding, Diagnosis, and Management of Tuberculous Mastoiditis in 4 Cases Sally Mahdiani; Lina Lasminingrum; Bambang Purwanto; Riri Handayani
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15944

Abstract

Background: Tuberculous mastoiditis is a rare case of chronic otitis media disease and extrapulmonary tuberculosis, caused by Mycobacterium tuberculosis. Case Presentation: Four cases of tuberculous mastoiditis were reported, ranging in age from 16 to 66 years. All patients presented with chronic discharge with signs of mastoiditis with intra and extratemporal complications. Two patients only manifested in the mastoid and two other patients had symptoms of tuberculosis in other organs, especially the lungs. All patients underwent radical mastoidectomy and histopathological examination showed tuberculosis. All patients received category 1 and category 2 antituberculosis drugs. Conclusion: The clinical features of tuberculous mastoiditis vary. Diagnosis of tuberculous mastoiditis can be done by histopathological examination and geneXpert. Surgical therapy and administration of antituberculosis are the main options in the management of tuberculous mastoiditis.
Heart Disease in Indonesia in 2018: An Ecological Analysis Haqqelni Nur Rosyidah; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16316

Abstract

Broccoli Effects on Hif-1 A in Spermatozoa Cells of Ratsthat Induces Psychological Stress Ahmad Nur Huda; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16334

Abstract

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Broccoli Effects on HIF-1 in Heart Endothelial Cells of Rats that Induces Psychological Stress Haqqelni Nur Rosyidah; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16341

Abstract

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Co-Authors AA Subiyanto Adelia Handoko Agus Sutardjo Ahmad Abdullah Ahmad Nur Huda Aldika Akbar, Muhammad Ilham Arifa Mustika Aryati Bambang Wirjatmadi Budi Prasetyo Darmika Caroline Didik Prasetyo Eko Budi Koendhori, Eko Budi Elyana Asnar Eman Sulaiman Erna Listyaningsih Esti Tantri Anandani Fitriana, Farida Gadis Meinar S Haqqelni Nur Rosyidah Hari Basuki Notobroto Hari Setiono Haryono Yuniarto Herdianty Kusuma I Gusti Bagus Wiksuana Idha Kusumawati Ilman F Martanegara Imam Susilo Indri Ngesti Rahayu Intan Herlina Irena May Rani Iwin Sumarman Izzati, Dwi Jusak Nugraha Kusnanto Kusnanto Lestari Wuryanti Lina Lasminingrum Lusi Mirnawati M. Yogiarto Made Dian Kusumawati Moh. Ali Azis Natasha Tiara Bernadette Nur Hayati Nurmala Nurmala Nurmala Nurmala Paulus Kusnanto Rahma Anindita Raihan Akbar Muhammad Refli Sudrajat Riri Handayani Rochana Ruliyandari Rohmatul Ummah Sally Mahdiani Semedi, Bambang Pujo Setiawan, Philia Shinta F Boesoirie Sony Wibisono Sugiarto Sugiarto Sumardi Maryono Suradi Maryono TATI NURHAYATI Teti Madiadipoera Tri Hardi Susanto Umi Khanifah Warigit Dri Atmoko Yoes Prijatna Dachlan Yopie Wiguna Yuan Guruh Pratama Yussy Afriani Dewi