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All Journal Folia Medica Indonesiana Window of Health : Jurnal Kesehatan Jurnal Respirasi (JR) UMI Medical Journal Green Medical Journal Jurnal EduHealth International Journal of Health and Pharmaceutical (IJHP) jpki

Wiriansya, Edward Pandu

Universitas Muslim Indonesia

Author-ID : 1212377

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Analisis Perbedaan Waktu Transportasi Mukosiliar Hidung Pada Perokok Dan Non Perokok Dengan Uji Sakharin Di Universitas Muslim Indonesia Permatasari, Dinda; Susilo, Wawan; Wiriansya, Edward Pandu; Abdi, Dian Amelia; Sanna, Andi Tenri
Window of Health : Jurnal Kesehatan Vol. 2 No. 4 (Oktober, 2019)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

The nose has a physiological function for example as a filter that is useful to clean the air of inspiration from dust, bacteria and viruses through a mechanism called the mucociliary transport system (TMS). This TMS mechanism functions to protect the upper and lower respiratory system by forming waves of sweeping on foreign objects such as dust and even microorganisms trapped in the mucous pallets. This study aims to determine whether there are differences in nasal mucociliary transport time in smokers and non-smokers. The material used in this study is sakharin which has a sweetness level 700 times sweeter than ordinary sugar. This study involved 50 research subjects who were divided equally into 2 groups, 25 smokers and 25 non-smokers. All subjects will be interviewed in the form of a questionnaire and then test the time of mucociliary transport of his nose using the sakharin test. The results of this study found that the average mucociliary transport time of the nose to non-smokers was 24.67 Â± 5.36 minutes and the mean time of mucociliary transport of the nose to smokers was 9.42 Â± 5.04 minutes. Obtained also the results of the average mucociliary transport time of noses in light smokers that is 24.2 Â± 5.4 minutes and the average mucociliary transport time of noses in moderate smokers is 27.9 Â± 3.94 minutes. It can be concluded that the difference in nasal mucociliary transport time was found in smokers and non-smokers where the mucociliary transport time in smokers was longer.

The Profile of Lung Adenocarcinoma Patients with Positive EGFR Mutation Pandu Wiriansya, Edward; Ainun; Ratu, Puspa; Muhammad Reza Cesarian Noor, Andi
Green Medical Journal Vol 2 No 1 April (2020): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Background: The high mortality rate in pulmonary carcinoma is a problem encountered in various countries, including Indonesia. According to WHO, there are 2.09 million people affected by lung cancer and 1.76 million deaths due to lung cancer worldwide. This study was aimed to determine the profile of lung adenocarcinoma patients with positive EGFR mutation. Methods: The study was descriptive study with cross-sectional approach using secondary data obtained from medical records of lung adenocarcinoma patients. Results: The present study revealed that lung adenocarcinoma was found higher in patients with age >40 years old (93.9%) compared to those with age <40 years old. It was also higher in male (66.7%) than in female patients. Most patient with lung adenocarcinoma were at the IIIB stage (42.4%). It was also reported that higher cases was found in patients with history of smoking more than 15 years (42.4%). Hemoptoe was the most reported clinical symptoms in patients with lung adenocarcinoma (87.9%). Lung adenocarcinoma was also observed higher in patients without family history of pulmonary adenocarcinoma (81.8%). Seventeen of 33 EGFR mutations (51.5%) were observed in exon 19 and fourteen (48.5%) were in exon 21. Conclusion: The most common EGFR mutation lung adenocarcinoma was observed in exon 19.

Gangguan Kepribadian Akibat Kecanduan Bermain Game Pada Gamers Wiriansya, Edward Pandu; Noor, Andi Muhammad Reza Cesaria; Rahman, Titin Suhartina; Abdi, Dian Amelia; Ratu, Andi Puspa
Window of Health : Jurnal Kesehatan Vol. 3 No. 3 (Juli, 2020)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33368/woh.v0i0.258

Electronic games or often referred to as online games, have experienced very rapid development and progress. This can be seen in various small cities in all corners of Indonesia, where many game centers have emerged. Even lately, the type and theme of the game that develops leads to the theme of violence that triggers aggressive behavior in adolescents. In addition, as the number of game addicts increases, the number of criminal acts triggered by the game increases. The purpose of this study was to determine the relationship of addiction to playing games with personality disorders in game players. This research uses observational analytic method with cross sectional design. The research subjects were game players in the Makassar City Game Center which were taken in total sampling. Data is collected using Game Addiction Scale (GAS) questionnaire, Mini International Neurophysciatric Interview (MINI), and game player data sheets. Hypothesis testing the correlation between addiction to playing games with personality disorders was analyzed by the two free sample T Test. Of the 50 gamers in the Game center that were sampled, there were 48 people who experienced personality disorders. Bivariate analysis of addiction to play games associated with personality disorders obtained p value = 0,000, the type of game not related to personality disorders obtained p value = 0.745, and the duration of playing games related to personality disorders obtained p value = 0.001. The conclusion is that there is a relationship between addiction and the duration of playing games with personality disorders. It is recommended not to always use the game so that it does not experience personality disorders.

Seorang Penderita dengan Infeksi Entamoeba Histolytica pada Pleura Edward Pandu Wiriansya
UMI Medical Journal Vol 1 No 1 (2016): December 2016
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Pada laporan kasus ini akan dipaparkan seorang penderita abses hepar yang menyebabkan terjadinya empiema. Tujuan laporan kasus ini adalah memaparkan kasus yang jarang terjadi dengan diagnosa empiema amuba torasis kanan dimana dibutuhkan diagnosa yang cepat dan tepat karena sering terjadi keterlambatan diagnosa dan penatalaksanaan yang tidak tepat akan memberikan prognosis yang buruk. Terapi antibiotik empirik yang diberikan sebelum pemeriksaan parasit pada penderita empiema dengan abses hepar dapat mengaburkan data insiden penyakit ini.

Perbedaan Status Gizi Penderita Tuberkulosis Paru Sebelum dan Sesudah Pengobatan Di RS Ibnu Sina Makassar Shofiyah Latief; Zulfahmidah zulfahmidah; Asrini Safitri; Edward Pandu Wiriansya; Muhamad Ilhamsyah Dandung
UMI Medical Journal Vol 6 No 1 (2021): Umi Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v6i1.133

Latar belakang: Tercatat, angka prevalensi kejadian TBC di Indonesia pada tahun 2014 sebesar 297 per 100.000 penduduk. Pada Sulawesi Selatan yang terkonfirmasi secara bakterilogis di antara semua pasien TB paru yang tercatat atau diobati mencapai 1,234 (20.97%) Hal ini belum mencapai target yang diharapkan. Metode: Penelitian ini adalah penelitian analitik komparatif dengan metode cross sectional dengan jumlah sampel 68 orang. Analitik data menggunakan Uji t sampel berpasangan. Hasil: Jenis kelamin laki-laki lebih tinggi sebesar 64,7% (44 orang) dan perempuan 35,3%(24 orang). Sampel pada usia tertinggi yaitu usia 18-28 tahun 26,5%(18 orang). Sampel sebelum pengobatan terbanyak dengan status gizi underweight 64,7%(44 orang). Sedangkan sampel sesudah pengobatan terbanyak dengan status gizi normal 51,5%(35 orang). Berdasarkan hasil analisis statistik didapatkan perbedaan yang signifikan antara status gizi pada penderita TB paru dewasa sebelum dan sesudah pengobatan. Kesimpulan: Terdapat perbedaan yang signifikan antara status gizi pasien penderita TB paru dewasa sebelum pengobatan dan sesudah pengobatan.

COMPARISON OF CHEMOTHERAPY RESPONSE AND ADVERSE EFFECTS OF DOUBLE-PLATINUM PLUS EGFR-TKI VERSUS DOUBLE-PLATINUM ALONE ON NSLCLC PATIENTS WITH DISEASE PROGRESSION AND EGFR-TKI TREATMENT Laksmi Wulandari; Edward Pandu Wiriansya
Folia Medica Indonesiana Vol. 53 No. 4 (2017): December 2017
Publisher : Faculty of Medicine, Universitas Airlangga

EGFR-TKI is the first-line therapy for EGFR-mutant patients. Nevertheless, patients will have disease progression (median PFS 10 – 12 months) due to resistance. The treatment options are still limited in developing countries for such cases, thus double-platinum chemotherapy is the next option. Although IMPRESS study reported no difference in terms of PFS and OS between double-platinum alone and double-platinum plus EGFR-TKI, several local studies reported benefit of continuing EGFR-TKI in combination with double-platinum chemotherapy (treatment beyond progression). This study aimed to compare chemotherapy effects of double-platinum plus EGFR-TKI versus double-platinum alone on patients with NSCLC progression after EGFR-TKI treatment. This was an analytical descriptive study using prospective cohort design, involving 30 patients with disease progression following EGFR-TKI treatment that met inclusion criteria in Dr. Soetomo Hospital. Subjects were divided into two groups: arm A (double-platinum plus EGFR-TKI) and arm B (double-platinum alone). Subjects were observed until 4 cycles of double-platinum chemotherapy. Subjective response (body weight and EQ5D questionnaire) was analyzed, chest CT scans were evaluated using RECIST criteria, and adverse effects were monitored. This study was conducted in accordance with GCP principles and has received ethics certificate from Dr. Soetomo Hospital ethics committee (No. 08/Panke.KKE/I/2017). The results showed that subject characteristics between two arms were insignificantly different (p=0.05). The most common EGFR mutation was exon 21 (50% on arm A and 60% on arm B). Chi square was tested on subjective response parameter (EQ5D (p=0.483)). T2 free sample was tested on semi-subjective parameter (body weight (p=1.00)). Comparison test on both groups after cycle 2 and 4 showed p value=0.05. Statistical test on adverse effect between both groups showed p value=0.526. As a conclusion, there was no significant difference between double-platinum and double-platinum plus EGFR-TKI on patients who had disease progression following EGFR-TKI treatment.

Tuberculous Lymphadenitis in Immunocompromised Patients: Case Series Edward Pandu Wiriansya; Irawaty Djaharuddin; Andi Tiara Salengke Adam
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Tuberculous lymphadenitis (TBLN) is a form of extra-pulmonary TB with clinical features ranging from lumps to abscesses. Human Immunodeficiency Virus (HIV) co-infection and diabetes mellitus alongside TBLN made the diagnosis and management exceptionally challenging. We reported 3 cases of TBLN, 2 among them had an existing HIV co-infection, and 1 had preexisting diabetes mellitus.Case: The first case, a 28-year-old man, previously diagnosed with HIV, complained of a lump in the neck; biopsy results suggested TBLN. The second case was a 36-year-old man with a neck abscess and HIV co-infection. Acid Fast Bacilli (AFB) pus was positive & Human Immunodeficiency Virus Enzyme-Linked Immunosorbent Assay (HIV ELISA) was reactive. The third case was a patient with a neck abscess with preexisting diabetes mellitus (DM) underwent wound debridement and was given anti-tuberculosis drugs.Conclusion: TBLN with HIV co-infection or diabetes had clinical features ranging from a painful lump to an abscess. The definitive diagnosis was taken by examining AFB from pus. If the abscess was more extensive than or equal to 3 cm, wound debridement was necessary. The primary treatment for TBLN was anti-tuberculosis drugs and required even greater attention if a patient had any preexisting comorbidities such as HIV and diabetes.

Mekanisme Kerja Antibiotik: Review Article Dwi Anggita; Siti Nurisyah; Edward Pandu Wiriansya
UMI Medical Journal Vol 7 No 1 (2022): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v7i1.149

Latar Belakang: Penggunaan obat-obatan yang tidak rasional adalah masalah yang tersebar luas di semua tingkat pelayanan kesehatan, terutama di rumah sakit. Penggunaan antibiotik di rumah sakit yang tidak perlu atau berlebihan mendorong berkembangnya resistensi terhadap bakteri tertentu. Adanya hubungan yang erat antara penggunaan antibiotik yang salah dengan timbulnya resistensi bakteri penyebab infeksi nosokomial. Sehingga penting diketahui mekanisme kerja antibiotik agar pemberiannya sesuai dengan bakteri penyebab suatu penyakit. Isi: Mekanisme kerja dari antibiotik yang dikelompokkan menjadi 3 kelompok besar yaitu antibiotik yang menargetkan dinding sel bakteri, antibiotik yang menghalangi produksi protein baru, dan antibiotik yang menargetkan replikasi DNA atau DNA. Kesimpulan: Antibiotik yang menargetkan dinding sel bakteri adalah golongan ß-laktam (penisilin, cefalosporin, karbapenem, dan monobaktam), glikopeptida, daptomisin, kolistin. Adapun antibiotik yang menghalangi sintesis protein adalah rifamisin, aminoglikosida, makrolid dan ketolide, tetrasiklin dan glisilsiklin, kloramfenikol, klindamisin, streptogram, linezolid, nitrofurantoin. Sedangkan antibiotik yang menargetkan DNA atau replikasi DNA antara lain sulfa, kuinolon, metronidazol.

Pengaruh Indeks Massa Tubuh (IMT) Terhadap Kapasitas Vital Paksa (KVP) pada Pasien PPOK di RS Ibnu Sina Makassar Nurfachanti Fattah; Zulfah Midah; Edward Pandu Wiriansya; Rachmat Faisal Syamsu; Arni Isnaini Arfah; Ahmad Fahd Alifian
UMI Medical Journal Vol 7 No 2 (2022): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v7i2.212

Latar belakang: Penyakit Paru Obstruktif Akut (PPOK) merupakan penyakit kronis yang berdampak pada derajat kesehatan pasien jangka panjang, salah satunya mempengaruhi status Indeks Massa Tubuh (IMT) seseorang. Perubahan tersebut dapat terjadi pada pasien yang menderita Penyakit Paru Obstruktif Akut (PPOK). Hubungan penting antara nutrisi dan PPOK ialah melalui efek katabolisme, salah satunya dengan melihat status gizi. Tujuan penelitian ini adalah untuk mengetahui Pengaruh Indeks Massa Tubuh (IMT) Terhadap Kapasitas Vital Paksa (KVP) pada pasien PPOK. Metode: metode penelitian cross sectional dengan pendekatan retrospektif dan menggunakan data sekunder berupa rekam medik yang diambil dari Rumah Sakit Ibnu Sina Makassar tahun 2021. Hasil: Berdasarkan uji chi square antara hubungan IMT terhadap KVP diperoleh bahwa, nilai p-value Pearson Chi Square sebesar 0,864 artinya lebih besar dari tingkat signifikansi 5% (0,05). Kesimpulan: Hasil penelitian didapatkan bahwa tidak ada pengaruh yang signifikan antara Indeks Massa Tubuh (IMT) dan Kapasitas Vital Paksa (KVP) pasien PPOK (p=0,864).

Support Kebut Vaksinasi Sulsel Tim Vaksinator Covid-19 Universitas Muslim Indonesia Arni Isnaini Arfah; Syamsu Rijal; Nasrudin AM2; Armanto Makmun; Asrini Safitri; Febie Irsandy; Yusriani Mangerangi; M. Hamsah; Fendy Dwimartyono; Muhammad Mursyid; Agung Dirgantara; Rahmawati Rahmawati; Anna Sari Dewi; Zulfiyah Surdam; Rasfayanah Rasfayanah; Andi Sitti Fahirah; Eny Arlini Wello; Zulfahmidah Zulfahmidah; Sri Wahyuni Gayatri; Dian Amelia Abdi; Edward Pandu Wiriansya; Zulfitriani Murfat; Lisa Yuniaty; Sri Wahyu; Arina Fathiyyah; Santriani Hadi
Jurnal Pengabdian Kedokteran Indonesia Vol 3 No 1 (2022): Maret 2022 (Reuploaded Article Due to Website Crushed Down Months Ago)
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Kegiatan yang berorientasi kepada masyarakat merupakan merupakan salah satu tridarma perguruan dibidang pengabdian. Kami dari dosen-dosen dan mahasiswa Universitas Muslim Indonesia Fakultas Kedokteran, Fakultas Kesehatan Masyarakat, (Prodi Kebidanan dan Keperawatan), Fakultas Farmasi, dan Rumah Sakit Ibnu Sina, dibawah arahan koordinasi Dekan Fakultas kedokteran UMI Ayahanda Prof. dr. H. Syarifuddin Wahid, Ph.D, Sp. PA (K), Sp.F berkoordinasi bersana dekan Fakultas Kesehatan Masyarakat (Ketua Prodi Keperawatan dan Kebidanan) serta dekan Farmasi menyalurkan bantuan tim vaksinator dalam mendukung peningkatan vaksin di Indonesia, khususnya di Kabupaten Takalar, Sulawesi Selatan atas himbauan dari Dinas Kesehatan Provinsi Kota Makasssar. Tujuan pengabdian ini untuk pencapaian target warga yang divaksin dapat mencapai target diatas 70%, baik vaksin pertama ataupun vaksin kedua. Adapun kegiatan ini dilaksanakan selama dua minggu sejak 20 - 31 Desember 2021 di beberapa titik desa Kabupaten Takalar, Sulawesi Selatan: wilayah Polut ada 5 kelurahan/desa, wilayah Marboada 5 kelurahan/desa, wilayah Pattalassang ada 5 kelurahan/desa, dan wilayah Galesong ada 9 kelurahan/desa. Diharapkan sebagai pengalaman dan pembelajaran agar segala kritik dan saran yang disampaikan dapat diperbaiki lagi pada kegiatan selanjutnya.

Co-Authors Abdi, Dian Amelia Agung Dirgantara Ahmad Fahd Alifian Ainun Andi Muhammad Luthfi Parewangi Andi Sitti Fahirah Andi Tenri Sanna Andi Tiara Salengke Adam Anggita, Dwi Anna Sari Dewi Arina Fathiyyah Armanto Makmun Arni Isnaini Arfah Asrini Safitri Asrini Safitri Asrini Safitri Dewi Rahman Dian Amelia Abdi Dinda Permatasari, Dinda Dzul Ikram Eny Arlini Wello Febie Irsandy Fendy Dwimartyono Fitrah Ahmad, Izhar Irawaty Djaharuddin Kasim, Sharen Laksmi Wulandari Lisa Yuniaty M. Hamsah Muh Anugrah Ramadhan Muhamad Ilhamsyah Dandung Muhammad Mursyid Muhammad Naufal Zuhair Muhammad Reza Cesarian Noor, Andi Nasrudin Andi Mappaware Noor, Andi Muhammad Reza Cesaria Nurfachanti Fattah Prema Hapsari Hidayati Puspa Ratu, Andi Rachmat Faisal Syamsu Rachmat Faisal Syamsu Rahman, Titin Suhartina Rahmawati Rahmawati Rahmawati, Rahmawati Rasfayanah Rasfayanah Ratu, Andi Puspa Ratu, Puspa Santriani Hadi Shofiyah Latief Siti Nurisyah Sri Wahyu Sri Wahyuni Gayatri Susilo, Wawan Syamsu Rijal Syamsu Rijal Utomo Andi Pangnguriseng Yusriani Mangarengi Zulfah Midah Zulfahmidah Zulfitriani Murfat Zulfiyah Surdam

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