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All Journal Jurnal Biomedika dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Lisnawati, Yuyun
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hubungan Parameter Laboratorium dengan Derajat Klinis COVID-19 pada Kehamilan Nirmalasari, Rully Ayu; Surjadi, Lily Marliany; Maharani, Laksmi; Lisnawati, Yuyun; Mangun, Dhea
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.291-299

Abstract

Background Pregnant women were one of the most susceptible groups because they are vulnerable to respiratory infection. They may get more severe symptoms due to their physiological changes during pregnancy including the immunological response. This study was performed to find whether there is an association between laboratory parameters (Hb, leukocytes, platelet, neutrophils, lymphocyte, monocyte, NLR, PLR and CRP) and the severity of Covid-19 infection in pregnant women. Methods This study is a retrospective cohort study using secondary data from patient’s medical records at Persahabatan General Hospital, Jakarta from March to June 2021. Results Pregnancy cases with COVID-19 in this study were in the mean of 29 year age. Most of them are in the third trimester of pregnancy. 80.5% from 67 patients have no- mild symptom while 19.5% have moderate to severe symptom. There are no difference in vital sign nor oxygen saturation at first admission. Lower level was found in the parameter of leukocyte, lymphocyte and monocyte.  Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein increase as the degree of severity increase.  The mean neutrophil in pregnant women with moderate to severe COVID-19 symptom was 80.49±7.47 while median NLR value was of 6.76 (2.73-18.71) . Conclusions Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein has associate significantly to severity symtomps of COVID-19 in pregnancy.
Luaran Bayi dari Ibu dengan Tuberkulosis Resistan Multi Obat Yusuf, Dwiyanarsi; Lisnawati, Yuyun
Majalah Kedokteran Indonesia Vol 69 No 4 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.4-2019-69

Abstract

Introduction: Multidrug-resistant TB (MDR-TB) is described as Mycobacterium tuberculosis infection resistant to rifampicin and isoniazide with or with-out resistance to other drugs. MDR-TB, if left untreated or undiagnosed inpregnancy, is associated with higher maternal morbidity, mortality, and increased risk of vertical transmission. There are increased risk of obstetrical complications like spontaneous abortions, fetal growth restriction, oligohydram-nios, preterm labor and increased neonatal mortality. Objective: This study was intended to present a case series of MDR-TB treat-ment among pregnancies and fetal outcome in our hospital. Methods: Evaluation of 3 pregnant woman who had been diagnosed with MDR-TB. Data were obtained by history taking, physical examinations, laboratory results and outcome of the neonates. Results: Two out of 3 pregnant woman were known resistant to rifampicin andwere given ethionamide and levofloxacin for more than a month. C-sectionwere performed in all pregnancies at 32 weeks, 36 weeks and 36 weeks withbaby weight 1450 gr, 2350 gr, and 2600 gr respectively. There was no congeni-tal abnormality found in all neonates. Conclusion: Case series of MDR-TB in pregnancy has been reported. Two outof 3 patients were received ethionamide and levofloxacin treatment during pregnancy, showed no deformity or congenital abnormality in the neonates. Low birth weight neonates were found in two patients.
Haruskah Plasenta Perkreta disertai Lakuna Bizarre? Yusuf, Dwiyanarsi; Khonsa, Oni; Apriliawan, Tri; Lisnawati, Yuyun
Majalah Kedokteran Indonesia Vol 69 No 8 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.8-2019-189

Abstract

Background: Placenta percreta is a life-threatening condition that requires multidisciplinary management. The incidence of placenta percreta increases with increasing incidence of cesarean section. Antenatal diagnosis is an important point to prevent morbidity and mortality in both mother and baby. Ultrasonography (USG) is one of the relatively cheaper and easier modalities for diagnosing placenta percreta. Objective: To identify the optimal ultrasonographic criteria for the diagnosis of placenta percreta.Methods: We followed 2 cases, which performed antenatal care (ANC). Both patients then performed an ultrasound examination according to the placenta accrete index (PAI) method. The ultrasound assessment findings are then compared with intraoperative clinical findings and histological features. Results: From two cases, we did not find any Bizarre lacuna, but a thin retroplacental myometrial layer was found accompanied by loss of clear zone. The findings on ultrasonography are in accordance with intraoperative findings and histological features, where the appearance of the placenta percreta is clearly visible.Conclusion: It is different from the assessment of PAI, where the presence of lacuna is the biggest predictive factor for placenta adhesiva, in both cases, a thin myometrial layer of retroplacenta accompanied by a clear clear zone, although no lacuna was found, sufficiently describe the placenta percreta
Karakteristik Klinik dan Analisis Faktor Risiko yang Berperan pada Derajat Keparahan Invasi Plasenta Abnormal di RSUP Persahabatan pada Tahun 2015-2018 Feharsal, Yuri; Lisnawati, Yuyun; Pudyastuti, Sri; Khonsa, Oni; Apriliawan, Tri; Botefilia, Botefilia; Nurfauziah, Nadia; Agustin, Kindy
Majalah Kedokteran Indonesia Vol 69 No 6 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.6-2019-195

Abstract

Background: Morbidly adherent placenta is a condition which placenta adheres and invades deeply into the myometrium and, in some cases, until uterine serosa, thus contribute to peri-partum hemorrhage and significant maternal mortality.Purpose: To identify prevalence, clinical characteristics and their odds ratio to increasing se-verity of morbidly adherent placenta case in RSUP Persahabatan from 2015 to 2018.Methods: Cohort retrospective study.Results: From 2015 to 2018, prevalence of morbidly adherent placenta was around 0.8%. The risk factors which contribute to increasing severity of morbidly adherent placenta were: age above 35 years (OR 1.6, 95% CI 0.41-6.24) and history of Caesarean section more than 2 times (OR 1.63, 95% CI 0.41-6.46). The presence of increasing severity of morbidly adherent placenta were related to volume of blood loss more than 1000 ml during surgery (OR 2.13, 95% CI 0.52-8.76). Conclusion: The prevalence of morbidly adherent placenta at Persahabatan General Hospital in 2015-2018 was 0.8%. Age, history of Caesarean section more than 2 times, volume of blood loss, and duration of surgery were not statistically associated with adherent placenta case.
Penularan COVID-19, Laporan Kasus Seorang Peserta Program Pendidikan Dokter Spesialis Obstetri dan Ginekologi Lisnawati, Yuyun; Ocviyanti, Dwiana; Wulan, Diyah Septiti
Majalah Kedokteran Indonesia Vol 70 No 12 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.12-2020-286

Abstract

Since COVID-19 first broke out in Jakarta in early March 2020, the infection rate has been slowly but surely increasing. Health workers who work directly to serve patients, including the resident, are vulnerable to infection. The following is a story of a Obstetrics and Gynecology resident who was infected with COVID-19 and managed to recover after going through a period of independent isolation. In March 2020, the resident who at that time served in the Obstetrics polyclinic at a COVID-19 referral hospital in Jakarta, experienced myalgia, fever, headache, sore throat, cough and runny nose. Due to the condition causes PPDS to be rested. Complaints improved within a few days, after taking medication and multivitamin supplementation. One week later, the resident with the other resident and staff conducted a nasopharyngeal swab examination at the hospital, then the samples were sent to Litbangkes for reverse transcription polymerase chain reaction (RT-PCR) examinations against SARS-CoV-2. The results were obtained 20 days later and the resident was declared positive. When the results came out, PPDS who already felt healthy were undergoing rotation in another hospital. Undergo a 2-week self-isolation protocol, nutritious intake, supplementation, exercise, positive thinking and continued prayer. Transmission of COVID-19 may occur while serving patients, social distancing and wearing less awake masks when with PPDS friends, midwives, nurses and staff. The long duration of the RT-PCR swab results makes it difficult for tracing, the risk of widespread transmission and delays in efforts to break the chain of transmission of COVID-19 besides disrupting education rotation.
Co-Authors Agustin, Kindy Botefilia, Botefilia Dwiana Ocviyanti Khonsa, Oni Laksmi Maharani Mangun, Dhea Nurfauziah, Nadia Rully Ayu Nirmalasari, Rully Ayu Sri Pudyastuti Surjadi, Lily Marliany TRI APRILIAWAN, TRI Wulan, Diyah Septiti Yuri Feharsal Yusuf, Dwiyanarsi