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All Journal Dentika Dental Journal Journal of Dentistry Indonesia Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Interdental Jurnal Kedokteran Gigi (IJKG) JOURNAL OF APPLIED SCIENCE (JAPPS)
Nasution, Aini Hariyani
Department Of Periodontic, Faculty Of Dentistry, Universitas Sumatera Utara, Medan, North Sumatra
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Clinically Effective Regenerative Therapy for Primary Endodontic Lesions with Secondary Periodontal Lesions: A Case Report Amalia, Martina; Budi, Budi; Kurmaena, Iceu Estu; Yanti, Nevi; Nurcahyanti, Hesty; Nasution, Aini Hariyani
Journal of Dentistry Indonesia Vol. 30, No. 3
Publisher : UI Scholars Hub

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Abstract

The diagnosis and prognosis of teeth with endo-perio lesions present a major challenge for dentists. Proper diagnosis is critical in determining treatment and the long-term prognosis. However, treating complex endodontic and periodontal lesions is one of the most common challenges in current clinical practice. The coexistence of pulpal and periodontal tissue damage may complicate diagnosis and further influence dental prognosis. This article consists of a case report evaluating the efficacy of xenografts and resorbable membrane pericardium in treating bifurcation lesions associated with periodontal lesions of the left mandibular first molar. A 22-year-old female patient was referred by conservative dentistry with complaints of gingival swelling on tooth 36 with furcation involvement associated with periodontal lesions. A gingivectomy was performed after the first stage of periodontal therapy because gingival swelling precluded endodontic treatment. After 3 months of endodontic treatment, the grade II bifurcated lesion had not yet healed, so regenerative surgery using xenografts and a resorbable pericardial membrane was performed. Periodontal treatment showed no gingival inflammation, and radiographic evidence showed bone improvement. Endo-perio lesions are complex in etiology and require a high degree of expertise to identify and treat them. Therefore, effective treatment of lesions requires collaboration between various multidisciplinary disciplines.
Efficacy of platelet-rich fibrin application for improving collagen density of gingival connective tissue in periodontitis-induced rabbits Nasution, Aini Hariyani; Dewanti, Wenny
Padjadjaran Journal of Dentistry Vol 34, No 1 (2022): March
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol34no1.31891

Abstract

Introduction: Due to the high prevalence of periodontal diseases that increase the possibility of tooth loss, platelet-rich fibrin (PRF) as a regenerative treatment has been proposed. PRF is a potential second-generation platelet concentrate and autologous healing biomaterial which contain growth factors that accelerate wound healing mechanisms. This study aimed to evaluate the efficacy of platelet-rich fibrin application to improve gingival connective tissue collagen density in periodontitis-induced rabbits. Methods: An experimental study with a post-test only control group design approach was conducted on 20 samples calculated using the Federer formula. Periodontitis was induced in ten rabbits with silk ligatures tied around the cervical region of central incisors teeth bilaterally for 14 days. After periodontitis occurred, phase I treatment was performed and followed by curettage. PRF was placed in the lower region as a treatment group using a split-mouth design, whereas a control group without PRF was in the upper jaw region. Subjects were euthanised after the 7th and 14th days of healing. Histopathological analysis was performed, and collagen density was quantified using ImageJ software. Statistical analysis was carried out using paired-T and two-way ANOVA tests. Results: There was a significant difference (p=0.001; p<0.05) in gingival connective tissue collagen density between treatment and control groups on the 7th and 14th days of observation. There was a significant increase in gingival connective tissue collagen density in the treatment group. Conclusion: Platelet-rich fibrin could improve gingival connective tissue collagen density in periodontitis-induced rabbits.
Co-Authors Amalia Leni Amalia, Martina Andrie Harmaji Armia Syahputra Boy Bachtiar Budi Budi Cut Ati Ningsih Desy Marlyn Situmorang Dian Anggraini Dody Widkaja Filya Suri Risky Nababan Gebby Gabrina Iqlima Salsabila binti Mohammad Irma Ervina Kurmaena, Iceu Estu Lidya Irani Nainggolan Martina Amalia Maulidatul Husna Nevi Yanti Nurcahyanti, Hesty Pitu Wulandari Priscillia Sekar Yosuana Rini Octavia Nasution Robert Lessang Tarigan, Cornelia Christy Wenny Dewanti, Wenny Widianto Meydhyono Yulianti Kemal Zulkarnain