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All Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Mandala Pengabdian Masyarakat Jurnal Buana Farma Jurnal Pengabdian Masyarakat Bhinneka Jurnal Sains dan Teknologi Farmasi Indonesia
Riasari, Hesti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Journal : Jurnal Buana Farma

 1 
A LITERATURE REVIEW: AKTIVITAS ANTIBAKTERI TANAMAN OBAT TERHADAP BAKTERI PENYEBAB PNEUMONIA Sinabutar, Rahel Margarenta; Nurfitriani, Iis; Maharani, Dinda Eka; Riasari, Hesti
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1382

Abstract

Pneumonia is an acute respiratory tract infection caused by various pathogenic bacteria, including Streptococcus pneumoniae, Staphylococcus aureus, and Klebsiella pneumoniae. The increasing prevalence of antibiotic resistance among these pathogens highlights the need for alternative therapeutic strategies derived from natural products. This study aimed to review the antibacterial potential of medicinal plants against pneumonia-causing bacteria and their underlying mechanisms. A systematic literature review was conducted by searching scientific articles in Google Scholar, PubMed, ScienceDirect, and MDPI. Articles were selected based on inclusion criteria covering antibacterial activity, active compounds, and reported mechanisms of action. A total of 30 eligible articles were analyzed descriptively. The medicinal plants reviewed include Etlingera elatior, Cassia alata, Morinda citrifolia, Melaleuca leucadendra, Momordica charantia, Guazuma ulmifolia, Artocarpus altilis, Acacia nilotica, Gynura procumbens, Trigona incisa propolis, and Ficus carica. These plants contain secondary metabolites such as flavonoids, alkaloids, saponins, tannins, and phenols, which exhibit antibacterial activity by disrupting cell membranes, inhibiting protein synthesis, interfering with essential enzymes, and inducing oxidative stress in bacteria. The findings indicate that medicinal plants hold great potential as complementary or alternative therapies for pneumonia caused by antibiotic-resistant bacteria; however, further research, particularly in vivo and clinical studies, is required to confirm their efficacy and safety.
REVIEW ARTIKEL: POTENSI FITOTERAPI DARI TANAMAN HERBAL DALAM PENANGANAN RHEUMATOID ARTHRITIS Nurhayati, Ismaya; Maulani, Sintia Putri; Lathifah, Meira H.; Riasari, Hesti
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1387

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the joints, resulting in progressive damage and a decreased quality of life for patients. Conventional therapies such as NSAIDs and DMARDs are indeed effective, but their long-term use carries the risk of serious side effects and high costs. Therefore, safer and more affordable alternative therapies are needed, one of which is through the use of medicinal plants. This study aims to examine the potential of herbal plants as an additional or alternative therapy for rheumatoid arthritis. The method employed is a literature study, involving the search and analysis of 31 scientific journals retrieved from academic databases, including Google Scholar, PubMed, ScienceDirect, and MDPI. The articles analyzed were selected based on certain criteria and contained information about the content of active compounds, pharmacological activity, and the mechanism of action of plants on the RA inflammation process. The results of the study showed that various herbal plants such as Zingiber officinale, Curcuma longa, Boswellia serrata, and Nigella sativa have significant anti-inflammatory and immunomodulatory activities. The active compounds in these plants work by inhibiting the inflammatory pathway and reducing the production of pro-inflammatory cytokines. In conclusion, medicinal plants have great potential to be used as additional therapy in the treatment of rheumatoid arthritis. However, further research is needed, especially clinical trials, to ensure the long-term safety and effectiveness of their use.
Co-Authors Baroroh, Umi Dewi Astriany Fitriansyah, Sani Nurlaela Komar Ruslan Wirasutisna Lathifah, Meira H. Maharani, Dinda Eka Maulani, Sintia Putri Melati, Novi Nanda Nanda Nelvi, Nelvi Nurfitriani, Iis Nurhayati, Ismaya Restiasari, Anggi Simanjuntak, Nela Sin, Cindy Wan Yik Sinabutar, Rahel Margarenta Siti Uswatun Hasanah Wibowo, Diki Prayugo Widowaty, Windy