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All Journal Biota Jurnal SainHealth INFOKUM Jurnal Ar Ro'is Mandalika (Armada)
Ekawati, Evy Ratnasari
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology

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CORRELATION OF VITAMIN D WITH ANTIBODY QUANTITY IN IMMUNOPROPHYLACTIC INDIVIDUALS Wiwis Wijayanti, Christina Destri; Ekawati, Evy Ratnasari; Pradana, Muhammad Sungging
INFOKUM Vol. 10 No. 5 (2022): December, Computer and Communication
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/infokum.v10i5.1208

Abstract

The development of the field of health technology that integrates with advances in the economic field has provided an increase in life expectancy in populations in various countries today, but it is a life expectancy. this longer has its own effect in the form of an increase in cases of chronic diseases The preventive measures of a disease provide an individual's ability to stay healthy, happy and able to do activities freely. Immunoprophylactic is a powerful strategy in the primary prevention of a disease. The application of vaccination as an immunoprophylactic part is able to provide a protective effect related to the production of antibodies. The purpose of this study was to find out how the role of vitamin D is related to the formation of antibodies in individuals who have been vaccinated. The results showed that most of the study subjects had vitamin D levels within normal limits and to determine the formation of antibodies obtained the presence of production antibodies in each study subject using the immunofluorescent antibody detection method. Test the proximity of the relationship between the two variables using pearson correlation test from 25 research data. The pearson correlation test showed significance p=0.704 where p>0.05 indicated the absence of correlation between the assessed variables. The effect of vitamin D on immune cells, especially those related to the process of producing antibodies is very complex where the possibility of tolerogenic influence is one of the influencing factors. Vitamin D receptors are known to be mostly expressed by immune cells but there are differences in control related to cell activity status, for example vitamin D receptors can decrease in when differentiation occurs into macrophage cells or dendritic cells. The conclusions of the study showed that the concentration of vitamin D in most of the study subjects has not had a significant effect on the immunity system assessed based on the detection of levels antibodies.
Study of the Efficacy of Different Concentrations of Alcohol-Based Hand Sanitizer in Preventing Pathogen Transmission Through Palms Ekawati, Evy Ratnasari; Santoso, Setyo Dwi; Pradana, Muhammad Sungging; Santoso, Andreas Putro Ragil; Hanum, Mufida; Khoir, Intan Wahyunillah Zaidah; Arifina, Rosyidatul
Biota Vol 10 No 2 (2024): Jurnal Biota 2024
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/biota.v10i2.23231

Abstract

An integral part of the human body is the hands, which most frequently come into contact with various items; they can be an intermediary for spreading infections from hands to food and potentially eaten by humans. Maintaining hand hygiene is the right strategy to avoid this spread, which includes using an alcohol-based hand sanitizer. This study examines the potential for varying concentrations of alcohol-based hand sanitizer to transmit pathogens through the palms. The form of research is a laboratory experiment with an appropriate research design. Test the antibacterial potential of variations in alcohol-based hand sanitizer concentrations of 40, 50, 60, 70, and 70% using well diffusion and dilution methods. The tests were done in quadruplicates. The test bacteria used are Escherichia coli, Enterotoxigenic Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. The results of the research showed that of the four variations in the concentration of alcohol-based hand sanitizer, the bacteriostatic ability against Salmonella typhimurium, Pseudomonas aeruginosa, and Klebsiella pneumoniae bacteria was at a concentration of 40% to 80%. The bactericidal activity at a concentration of 80% was demonstrated by Escherichia coli, Enterotoxigenic Escherichia coli, and Staphylococcus aureus. Bactericidal activity was demonstrated against Escherichia coli, Enterotoxigenic Escherichia coli, and Staphylococcus aureus at an 80% concentration.
Uji Potensi Antibakteri Ekstrak Kulit Jeruk Nipis Citrus aurantifolia (Christm) Swingle Terhadap Vibrio sp. Prasetya, Indra Adi Wira; Aziz, Aziz; Ekawati, Evy Ratnasari; Pradana, Muhammad Sungging; Batati, Nadiah Al; Pratiwi, Esti Rizkiana
Jurnal SainHealth Vol. 7 No. 1 (2023): Maret 2023
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v7i1.6731.9-14

Abstract

Lime (Citrus aurantifolia) is one of the herbal plants that is rich in benefits, especially as a herbal medicines. Besides of lime fruit, lime peel also has antibacterial properties such as essential oils which contain flavonoids which can inhibit bacterial growth. This research utilizes lime peel which will be extracted as a test material. The purpose of this research is to determine the antibacterial potential of lime peel extract against Vibrio sp. at various concentrations. This research used the well-diffusion method using MHA as a test medium to determine whether lime peel extract can inhibit the growth of Vibrio sp. Various concentrations and penicillin as a positive control used in this research to determine which concentration has a greatest potential for inhibiting the growth of Vibrio sp. Result of this study used qualitative analysis by comparing the clear zone size produced on the medium. The obtained result shown that 20%, 40%, 60%, 80% and 100% concentration of lime peel can forming a clear zone which mean they can inhibit the growth of  Vibrio sp. The best concentration used to inhibit Vibrio sp. is 100% concentration which produce 23.7 mm clear zone on MHA medium. Lime peel extract can be used to inhibit Vibrio sp. growth based on the research result.
Study of Secondary Metabolites of Azolla Microphylla as Candidates for Aedes Aegypti Mosquito Repellents Pradana, Muhammad Sungging; Ekawati, Evy Ratnasari; Yusmiati, Siti Nur Husnul
Jurnal Ar Ro'is Mandalika (Armada) Vol. 5 No. 2 (2025): JURNAL AR RO'IS MANDALIKA (ARMADA)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/armada.v5i2.4958

Abstract

Dengue fever (DHF) is a disease that becomes an epidemic in an area every year. Prevention of the spread of DHF has been widely carried out as well as for vector bites. The use of repellent as one way to protect humans from mosquito bites. Alternative to the use of chemicals through the use of plants to repel mosquitoes need to be introduced. Mosquito repellents using plant-based ingredients have the advantage of being easily decomposed in nature. The aim of this study is to determine the content of secondary metabolites that can be used as mosquito repellents through multilevel extraction and to test the effectiveness of secondary metabolite content on the repellent power of Aedes aegypti mosquitoes. This study is an experimental study using 3 types of solvents with different levels of polarity. The results of the study obtained were positive for flavonoids with ethyl acetate solvent, positive for tepenoids and tannins with ethanol solvent. The positive compounds from the Azolla extract have the potential to repel mosquitoes.
UJI DAYA HAMBAT EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten) Steenis) TERHADAP PERTUMBUHAN BAKTERI Proteus vulgaris: INHIBITORY ACTIVITY OF BINAHONG LEAF EXTRACT (Anredera cordifolia (Ten) Steenis) ON THE GROWTH OF Proteus vulgaris BACTERIA Khusniyah, Nisfatul; Ekawati, Evy Ratnasari; Sundari, Titik
Jurnal SainHealth Vol. 9 No. 1 (2025): Maret 2025
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v9i1.16914.13-20

Abstract

Herbal plants in Indonesia have been widely used as traditional medicine. One natural resources is binahong leaves (Anredera cordifolia (Ten) Steenis). Microorganisms, namely bacteria, usually cause infectious diseases. Proteus vulgaris, is a common species of Proteus that is associated with infections in humans. This research aims to find out whether Binahong (Anredera Cordifilia (Ten) Steenis) leaf extract can inhibit the growth of Proteus vulgaris bacteria. The method used in this research is experimental. The subject of this research is Binahong (Anredera Cordifilia (Ten) Steenis) leaf extract dissolved in 96% ethanol. which was evaporated using a rotary vacuum evaporator. The inhibition test was carried out using well diffusion technique on Mueller Hinton Agar media Proteus vulgaris, the conclusion of this research is that concentrations of 20% 40% 60% 80% and 100% can be classified as moderate inhibitory activity.
KORELASI KADAR HbA1c DENGAN MIKROALBUMINURIA PADA PASIEN DIABETES MELITUS DI KLINIK DAN LABORATORIUM BUNDA MULIA LUMAJANG: CORRELATION OF HbA1C WITH MICROALBUMINURIA IN DIABETES MELLITUS AT BUNDA MULIA CLINIC AND LABORATORY LUMAJANG Rini, Yenny Puspa; Taharani, Wiwin Duata; Ekawati, Evy Ratnasari; Sundari, Titik
Jurnal SainHealth Vol. 9 No. 1 (2025): Maret 2025
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v9i1.16942.41-46

Abstract

Diabetes Mellitus (DM) is a disease caused by the failure of the pancreas to carry out its function, namely to produce insulin. Lack of insulin will cause increased levels of glucose in the blood or also known as hyperglycemia. HbA1c and Microalbuminuria are screening tests used to detect the early onset of diabetic nephropathy. The purpose of this study was to determine whether there was a correlation between HbA1c levels and microalbuminuria in diabetes mellitus patients at Bunda Mulia Lumajang Clinic and Laboratory. The research method was descriptive analytic. The subjects of this study were Diabetes Mellitus prolanis patients at Bunda Mulia Lumajang Clinic and Laboratory who were taken randomly as many as 50 patients.. The results of this study are that there is a unidirectional positive relationship with a strong correlation between HbA1c levels and microalbuminuria in diabetes mellitus patients, with a correlation value of 0.722. Based on the results, can be concluded that there was a strong and positive correlation between HbA1c and urine microalbumin in diabetes mellitus patients.
Co-Authors Andreas Putro Ragil Santoso, Andreas Putro Ragil Arifina, Rosyidatul Aziz Aziz Batati, Nadiah Al Hanum, Mufida Khoir, Intan Wahyunillah Zaidah Khusniyah, Nisfatul Pradana, Muhammad Sungging Prasetya, Indra Adi Wira Pratiwi, Esti Rizkiana Rini, Yenny Puspa Santoso, Setyo Dwi Taharani, Wiwin Duata TITIK SUNDARI Wiwis Wijayanti, Christina Destri Yusmiati, Siti Nur Husnul