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Nephroprotective effect of virgin coconut oil in Plasmodium berghei ANKA infected Balb/c mice Syafarinah Nur Hidayah Akil; Heny Arwati; Puspa Wardhani; Priangga Adi Wiratama
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 2 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i2.5791

Abstract

AbstractMalaria is a parasitic infectious disease caused by Plasmodium, which remains a world health problem with an estimated 219 million cases worldwide. In severe malaria infection, several organs of the body can be affected, including the kidneys. One of the pathophysiology associated with the worsening of this disease is oxidative stress. The use of antioxidants is expected to prevent this, and one product that has a high antioxidant content is virgin coconut oil (VCO). This study aimed to analyze the effect of VCO on the kidney in Plasmodium berghei ANKA-infected mice. This study was an in vivo laboratory experimental study with a randomized post-test only control group design using 35 BALB/c mice infected with P. berghei ANKA, weighing 20-30 grams. VCO with the Javara® brand is used with doses of 1, 5, and 10 ml/kg body weight (kgBW)/ day. The parameter assessed were levels of BUN, creatinine, and renal histopathological changes. The administration of VCO on the treated group shows minimal tubular necrosis and glomerulonephritis compared to the negative control group. The BUN and creatinine levels in the treated group were also lower than the negative control group. The results showed that VCO has a nephroprotective effect against P. berghei ANKA infection in mice.Keywords: malaria, kidney, virgin coconut oil
The clinical and histopathological aspect of the liver, lung, and kidney in Malaria Syafarinah Nur Hidayah Akil
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 3, No 2 (2019)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v3i2.2833

Abstract

Malaria is an infectious disease with worldwide distribution. The symptom ranges from asymptomatic to severe malaria that could cause mortality. Sequestration and rosetting in the capillaries of several organs in combination with the host inflammatory and immune response could cause multi-organ dysfunction including brain, liver, lung, kidney, etc. This review is to summarize the clinical and histopathological aspect of the disease, especially in lung, liver, and kidney. The clinical importance of severe malaria in the lung are acute lung injury or acute respiratory distress syndrome, jaundice in the liver, and acute kidney injury in the kidney. The histopathological change, in general, is the sequestration of infected erythrocytes in the capillaries of the organ. In the lung, the main changes are seen especially the septa. While in the liver, there are various changes including Kupffer cells hyperplasia, the proliferation of portal tract and bile duct, etc. In the kidney, the changes are in the glomerulus, tubules, and interstitial.
Diagnosis and management of acute rheumatic fever Irma Kartika; Syafarinah Nur Hidayah Akil
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.19023

Abstract

Acute rheumatic fever is a nonsuppurative, immune-mediated consequence of group A streptococcal pharyngitis. Recurrent or severe acute rheumatic fever can cause permanent cardiac valve damage and rheumatic heart disease. Universally, the most common major manifestations during the first episode of ARF remain carditis and arthritis. Subclinical carditis now can fulfils a major criterion for ARF in all populations as in revised Jones criteria – AHA 2015. Many of the clinical features of ARF are non-specific, so a wide range of differential diagnoses should be considered. Primary prevention requires accurate recognition and proper antibiotic treatment of GAS pharyngitis. Prevention of recurrent attacks of rheumatic fever (secondary prevention) is the most cost-effective way of preventing further rheumatic heart disease (RHD). Penicillin remains the antibiotic of choice. Intramuscular penicillin is preferred as it is more effective than oral penicillin and results in better compliance.
Peningkatan Pengetahuan Kanker Payudara Melalui Program Education To Prevent Breast Cancer (C-TOPRAC) Hidayah Akil, Syafarinah Nur; Pratiwi, Dewi; Mukti Widagda, Tasya Mutia; Puteri, Aulia Rahman; Annisya, Emmy Indri
Jurnal Visi Pengabdian Kepada Masyarakat Vol. 5 No. 1 (2024): Jurnal Visi Pengabdian Kepada Masyarakat : Edisi Februari 2024
Publisher : LPPM Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51622/pengabdian.v5i1.1412

Abstract

Insiden kanker payudara terus mengalami kenaikan secara global termasuk di Indonesia. Hal ini disebabkan oleh beberapa hal seperti keterlambatan deteksi dini, kesadaran yang rendah untuk melakukan deteksi dini kanker payudara, kurangnya efektivitas program deteksi di tingkat fasilitas kesehatan primer, serta perubahan pola gaya hidup di masyarakat yang buruk. Pengetahuan masyarakat mengenai kanker payudara dan keterampilan Pemeriksaan Payudara Sendiri (SADARI) masih terbatas. Kegiatan pengabdian masyarakat dengan judul Education to Prevent Breast Cancer atau disingkat C-TOPRAC ini dilakukan dengan tujuan untuk meningkatkan kesadaran dan wawasan mengenai kanker payudara. Metode yang digunakan adalah kampanye edukasi dengan menggunakan media poster, aplikasi messenger, dan media sosial. Tingkat pengetahuan peserta diukur dengan tes sebelum dan sesudah rangkaian seluruh kegiatan. Hasil yang didapatkan yaitu terjadi peningkatan pengetahuan tentang kanker payudara dan keterampilan SADARI pada masyarakat setelah pemberian edukasi dan pelatihan.
Pulmonary Embolism in the Post-partum Period: A Case Report Irma Kartikasari; Syafarinah Nur Hidayah Akil
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 2 (2024): September 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i2.3246

Abstract

Background: One well-known hypercoagulable state that raises the risk of venous thromboembolism is pregnancy and it is more common in cesarean delivery. Pulmonary embolisms are difficult to identify based solely on postpartum symptoms. Most of the symptoms are non-specific, therefore they are typically underdiagnosed throughout pregnancy and the postpartum period. Objective: This work presented information on the treatment of high-risk pulmonary embolism in the postpartum phase. Case presentation: This paper reported the case of a 33-year-old female, admitted to the emergency room for shortness of breath. Her personal history showed that she had just given birth to her sixth child by caesarian section a month ago and had a history of hysterectomy due to severe infection. Result: She suffered a high-risk pulmonary embolism in the post-partum period. It takes a strong index of suspicion to diagnose and treat patients in a timely manner. Conclusion: Echocardiography and Multislice Computerized Tomography are the best diagnostic methods. Venous thromboembolism prophylaxis should be taken into account, particularly in patients who have risk factors.
Personal Hygiene dan Pengetahuan Pasien Skabies di RSUD Soegiri Lamongan Zulfikar Marwan; Syafarinah Nur Hidayah Akil; Yuli Wahyu Rahmawati; Ridha Ramadina Widiatma
JurnalMU: Jurnal Medis Umum Vol 1 No 3 (2024): Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v1i3.24773

Abstract

Indonesia merupakan negara beriklim tropis dimana proses perkembangan bakteri, parasit, maupun jamur sangat mudah terutama pada kulit. Kejadia skabies masih tinggi di Indonesia dimana penyebaran penyakit tersebut dipengaruhi oleh personal hygiene dan pengetahuan. Penelitian ini bertujuan untuk mengetahui jumlah pasien skabies serta menganalisis hubungan antara personal hygiene dan pengetahuan dengan tingkat keparahan skabies di RSUD Soegiri Lamongan. Penelitian ini bersifat kuantitatif dengan metode observasi analitik dan menggunakan rancangan potong lintang. Jumlah sampel sebanyak 48 responden yang diambil dengan pengambilan secara consecutive sampling. Hasil penelitian ini menunjukkan bahwa personal hygiene sebagian besar sudah baik (87,5%). Namun, pengetahuan responden terkait skabies masih belum baik bahkan masih terdapat 17,5% responden berpengetahuan buruk. Personal hygiene dan pengetahuan berhubungan dengan kejadian skabies. Adanya hubungan yang signifikan menunjukkan bahwa personal hygiene dan pengetahuan responden berhubungan dengan tingkat keparahan skabies.
Hubungan Antara Kepatuhan Antenatal Care (ANC) dengan Kejadian Kekurangan Energi Kronis (KEK) di Puskesmas Prambontergayang Kabupaten Tuban Fakhrurrozaq, Hilal; Ariningtyas, Ninuk Dwi; Akil , Syafarinah Nur Hidayah; Absor , Sholihul
JurnalMU: Jurnal Medis Umum Vol 2 No 1 (2025): Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v2i1.25630

Abstract

Latar Belakang: Ketidakpatuhan kunjungan antenatal care (ANC) merupakan faktor risiko kekurangan energi kronis (KEK). Di Kabupaten Tuban pada tahun 2023, KEK mencapai 7,8% dan AKI terdapat 6 kasus. KEK pada ibu hamil perlu mendapat perhatian karena menyebabkan komplikasi seperti perdarahan, infeksi, hingga kematian. Tujuan: Mengetahui hubungan antara kepatuhan kunjungan antenatal care (ANC) dengan kejadian kekurangan energi kronis (KEK) di Puskesmas Prambontergayang Kabupaten Tuban. Metode: Penelitian ini menggunakan jenis penelitian kuantitatif analitik observasional dengan desain cross-sectional. Populasi penelitian ini adalah ibu hamil yang berkunjung antenatal care periode Januari – Desember 2023. Besar sampel penelitian ini berjumlah 319 ibu hamil dan diambil dengan cara stratified random sampling. Data berupa data sekunder yang diambil dari pihak rekam medis Puskesmas Prambontergayang. Hasil: Uji korelasi chi-square menunjukkan nilai p 0.002 < 0.05 pada kepatuhan antenatal care dengan kekurangan energi kronis. Kesimpulan: Terdapat hubungan antara kepatuhan antenatal care dengan kejadian kekurangan energi kronis di Puskesmas Prambontergayang Kabupaten Tuban. Kata Kunci : Kehamilan, kepatuhan antenatal care, kekurangan energi kronis.
WHEN MOTIVATION DOESN’T PREDICT ACADEMIC PERFORMANCE: A CROSS-SECTIONAL STUDY AMONG MEDICAL STUDENTS Madani, Muhammad Tazkia; Akil, Syafarinah Nur Hidayah; Yuliyanasari, Nurma; Utama, Reza
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 14, No 4 (2025): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.106516

Abstract

Background: Learning motivation is one of the internal psychological factors that influence student academic achievement. The strength and consistency of this relationship remain under debate. However, it encourages the importance of research to determine the role of motivation in academic achievement.Aims: This study aims to determine the relationship between learning motivation and MCQ block exam results in undergraduate medical students.Methods: This research is an observational analytic quantitative study with a cross sectional approach. The study population was second to fourth year preclinical students. Sampling with proportionate stratified random sampling obtained 196 students. Learning motivation was assessed using a validated instrument, the MSLQ, and academic performance was measured by the students’ latest block MCQ examination score. Spearman correlation tests were performed on the relationship. Results: The highest average learning motivation is found in the extrinsic dimension (94.9%), followed by the dimensions of task values and learning of belief (94.4%), intrinsic dimensions (84.7%), and self-efficacy (84.2%). Highly motivated students scored lower (66.9%) than moderately motivated students who scored lower (76.2%). However, the analytic revealed no statistically significant correlation between learning motivation and academic performance (p>0,05). Conclusion: Even though there were high importance of motivation in learning, this study found no significant correlation between learning motivation and academic performance.
Penanganan Malaria pada Pandemi COVID-19 Syafarinah Nur Hidayah Akil
PROCEEDING UMSURABAYA 2020: Prosiding Seminar Online UPDATES ON COVID-19 : MULTIDICIPLINARY PERSPECTIVE
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

AbstractThe current COVID-19 pandemic has caused more than 1 million deaths, with more than 37million cases known worldwide. This condition affects health management, including malariainfection. There is a possibility that malaria's morbidity and mortality may increase due tobarriers to access to health facilities. This article aims to discuss malaria control in theCOVID-19 pandemic, including the adaptation of service procedures in Indonesia. The directresponse to COVID-19 must be integrated with malaria control efforts. Access to malariaservices must be ongoing, and malaria control such as the distribution of insecticide-treatedbed nets must still be done. Surveillance activities can be carried out while still paying attentionto the use of PPE according to the protocol for preventing the transmission of COVID-19.Keywords: covid-19, malaria, malaria control
Analisis Tingkat Kepuasan Mahasiswa Terhadap Ujian Soca Di Fakultas Kedokteran Universitas Muhammadiyah Surabaya Christian Wijaya; Muhammad Anas; Gina Noor Djalilah; Syafarinah Nur Hidayah Akil
JurnalMU: Jurnal Medis Umum Vol 3 No 1 (2026): JurnalMU : Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v3i1.32618

Abstract

Latar belakang: Ujian Student Oral Case Analysis (SOCA) merupakan model evaluasi berbasis lisan dalam pendidikan kedokteran yang diterapkan di Fakultas Kedokteran Universitas Muhammadiyah Surabaya sejak tahun 2023. Ujian ini bertujuan menilai kemampuan pemahaman klinis, berpikir kritis dan sistematis, serta keterampilan komunikasi mahasiswa. Mengingat peran penting ujian SOCA dalam penilaian, sehingga tujuan penelitian ini adalah untuk menganalisis tingkat kepuasan mahasiswa terhadap ujian SOCA. Metode: Penelitian ini menggunakan pendekatan mixed methods dengan kombinasi kuantitatif dan kualitatif. Sampel penelitian sebanyak 174 mahasiswa Fakultas Kedokteran yang telah mengikuti ujian SOCA diambil dengan metode stratified random sampling. Data dikumpulkan melalui kuesioner berbasis model SERVQUAL yang mencakup lima dimensi, yaitu tangibles, reliability, responsiveness, assurance, dan empathy. Analisis dilakukan secara deskriptif menggunakan perangkat lunak SPSS versi 25. Hasil: Temuan penelitian ini menunjukkan bahwa dimensi responsiveness memperoleh skor rata-rata tertinggi (mean = 3,46), disusul tangibles (mean = 3,44), reliability (mean = 3,41), assurance (mean = 3,35), dan empathy yang merupakan dimensi dengan skor terendah (mean = 3,32). Secara umum, mahasiswa merasa puas terhadap pelaksanaan ujian SOCA. Kesimpulan: Tingkat kepuasan mahasiswa terhadap ujian SOCA berada pada kategori baik di seluruh dimensi SERVQUAL. Diperlukan perbikan pada aspek empati dan objektivitas evaluasi guna meningkatkan mutu pelaksanaan ujian SOCA secara menyeluruh.