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All Journal Indonesian Journal of Tropical and Infectious Disease Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Biomolecular and Health Science Journal International Islamic Medical Journal Biomedika Jurnal Medis Umum
Ayu Lidya Paramita
Universitas Muhammadiyah Surabaya
Religion Humanities Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Medical students' perspectives about distance learning during early COVID 19 pandemic: a qualitative study Muhammad Reza Utama; Yelvi Levani; Ayu Lidya Paramita
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.5000

Abstract

Background: Medical education throughout the world has experienced major changes as a consequence of the presence of the COVID-19 pandemic. The Government of Indonesia has instructed physical distancing so that teaching and learning activities, including in the Faculty of Medicine, must be carried out at home with online methods to reduce the risk of COVID distribution. Objective: to explore undergraduate medical students’ perspectives towards distance learning during early COVID 19 pandemic at Muhammadiyah Surabaya University - Faculty of Medicine (MSU-FM), Indonesia. Methods: a qualitative study of students’ online survey responses had been done. Thematic analysis based on Unified Theory of Acceptance and Usage of Technolgy (UTAUT) constructs was done to ecplore students’ perspectives. Results: Students have a positive perspective related to performance expectancy of distance learning. This factor have been perceived as factor that support the behavior of the use of distance learning in order to increase cognitive involvement in the learning process. However, in this study, other factors conveyed by students limiting their optimal use of current distance learning platform. Conclusion: Students‘ user experiences must be developed and maintained continuously during this pandemic era. Longitudinal studies that investigate the long-term impact of various distance learning platforms‘ usage also need further study.
The Presence of Other TB Cases in the Family as a Substantial Factor Influencing the Level of Knowledge and Perception of TB patients Yelvi Levani; Ricky Indra Alfaray; Rahmat Sayyid Zharfan; Astri Dewayani; Kartika Afrida Fauzia; Batsaikhan Saruuljavkhlan; Ayu Lidya Paramita; Maya Rahmayanti; Nur Mujaddidah Mochtar; Kamal Musthofa; Dede Nasrullah; Mohammad Subkhan
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.25690

Abstract

Introduction: Indonesia is still among the top three contributors to the number of Tuberculosis (TB) patients in the world in 2017. The awareness about TB can be affected by the presence of other TB patients in the family. Perception and good knowledge in TB patients can increase obedient in treatment. This study aims to relate to the presence of other TB patients in the family environment with knowledge of TB patients.Methods: This study used cross-sectional design. Research respondents have taken using the consecutive sampling technique. Respondents were TB patients on category one anti-tuberculosis treatment at Siti Khadijah Sepanjang Hospital and several primary health centers in Sidoarjo region during February-March 2019. This study used a questionnaire which included sociodemographic, level of knowledge, and perception about TB.Results: The number of respondents in this study was 50 people aged 22-67 years old. The level of knowledge of the respondents was mostly good (82%) as well as perceptions regarding TB (78%). Of the 50 patients, 17 patients (34%) claimed some families also suffered from TB. The comparison between group with other TB patient and group without other TB patients in the family showed significantly different result in the level of knowledge (p=0,000) and perception (p=0,000). The presence of other TB cases in family increased level of knowledge and perception regarding TB significantly.Conclusion: The presence of other TB patients in the family environment can increase awareness so that it can increase the interest of TB patients to find information about TB. 
Epidemiology of Escherichia coli as a Critical Pathogen of Bloodstream Infection Patients in Tertiary Referral Hospital Endraswari, Pepy; Mertaniasih, Ni Made; Setiawan, Firman; Paramita, Ayu Lidya
Indonesian Journal of Tropical and Infectious Disease Vol. 10 No. 3 (2022)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v10i3.39494

Abstract

Bloodstream infections (BSI), caused primarily by multidrug-resistant Escherichia coli, are a significant cause of morbidity and mortality worldwide. This study aims to evaluate the epidemiology of E. coli as a critical pathogen in patients with bloodstream infections in a tertiary referral hospital. This is a retrospective study using a  descriptive observational research design. This study used a medical record instrument for bloodstream patients in Dr. Soetomo Hospital's inpatient ward with Gram-negative bacteria results of blood cultures in the Clinical Microbiology Laboratory from April 2021 to September 2021. The observed variables include; antimicrobial sensitivity, patient clinical characteristics, demographic data, clinical diagnosis, and clinical outcome. In 6 months, 276 Gram-negative bloodstream infection patients were treated at Dr. Soetomo Hospital. The proportion of E. coli was 17 %.  The main characteristics of patients were over 60 years old (28%), and 54% were female. 63% of E. coli were ESBL, and 9% were carbapenem-resistant microorganisms. High antimicrobial resistance was found in quinolones (100%), ampicillin (93%), piperacillin (74%), tetracycline (72%), ceftriaxone (66%), cefotaxime (65%), ceftazidime (60%), cefazolin (65%), and trimethoprim-sulfamethoxazole (65%). The most common potential determinant profile discovered was linked to immunocompromised status due to malignancy.  The high number of antimicrobial-resistant bacteria showed the importance of strict infection control and updated epidemiology data as a guide for empirical antimicrobial therapy.
The Usage of Influenza Vaccine to Prevent Seasonal Influenza during Pandemic COVID-19 Levani, Yelvi; Paramita, Ayu Lidya
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 2 (2021): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.8.2.2021.93-101

Abstract

Influenza is an acute respiratory disease caused by influenza virus. Influenza can affect million people in every year and causing morbidity. Some of cases can be severe and need hospitalized, especially in elderly people. Influenza is an airborne disease and can spread rapidly. Every seasonal flu can be different because Influenza virus do mutation. Influenza vaccine can reduce morbidity and mortality. There are two types of influenza vaccine; live attenuated influenza virus (LAIV) and inactivated influenza virus (IIV). The newest type of influenza vaccine consists four types of virus (quadrivalent), therefore it gives more protection compared to the older one. Influeza vaccine is still recommended during pandemic COVID-19 because it can prevent co-infection between Influenza and COVID-19. In addition, it can reduce the morbidity and mortality during pandemic COVID-19.
Double infection by Multi-Drug Resistant Escherichia coli bacteria: A case report Paramita, Ayu Lidya; Ievani, Yelvi
Jurnal Medis Islam Internasional Vol 6 No 1 (2024): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v6i1.6286

Abstract

Introduction: Antimicrobial resistance (AMR) is a global issue causing multidrug-resistant bacterial infections, leading to higher morbidity and mortality rates. Escherichia coli, a Gram-negative Enterobacterales bacteria, is the predominant cause of common diseases. In 2018, Escherichia coli ESBL (beta-lactamase enzyme Extended-spectrum) bacterium had the highest antibiotic resistance in Surabaya, Indonesia. In 2022, 3rd generation cephalosporin-resistant E. coli and carbapenem-resistant E. coli were the top priority pathogens in Indonesia. Case: A one-year-old girl was taken to the emergency room after vomiting seven times and vomiting. She had a fever for one week, and her nose was runny. The patient had kidney channels narrowed and had surgery to implant a DJ stent in her right kidney five months prior. Physical examination revealed anemia, jaundice, cyanosis, and dyspnea. Blood and urine cultures were conducted, and Escherichia coli bacteria were found in urine and blood samples. Escherichia coli ESBL was found to be sensitive to several drugs, while its blood showed it was carbapenem-resistant, only sensitive to Ceftazidim, Amikacin, Gentamicin, Tigecycline, and Cefoperazone Sulbactam. Discussion: Pediatric patients often experience urinary infections from Escherichia coli (ESBL) and bloodstream infections from Escherichia coli (CRE). These bacteria colonize various sites in the human body, including the urinary tract, causing diarrhea and causing cystitis. ESBL, or Extended Spectrum b-lactamase, breaks down antibiotics, making them ineffective for treating infections. ESBL production is associated with a bacterium found in the bowel, and resistance genes are often transmitted through plasmids carrying other resistance genes. The emergence of carbapenem-resistant Escherichia coli isolates (CREC) has led to using polymyxin, tigecycline, fosfomycin, and aminoglycosides as effective antibiotics against CREC. CREC can lead to severe infections, including intra-abdominal infections, pneumonia, urinary tract infections, and device-associated infections. Conclusions: Escherichia coli, an MDRO bacteria, requires antibiotic sensitivity test results for effective treatment, with sensitive drugs often chosen in difficult cases, and requiring source control.
Antibacterial Activity of Aqueous Extract Combination of Garlic (Allium sativum) and Red Ginger (Zingiber officinale var. Rubrum) Against Staphylococcus aureus Rahma, Rizka Aulia; Paramita, Ayu Lidya; Akil, Syafarinah Nur Hidayah
Biomedika Vol 17, No 1 (2025): Biomedika Februari 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i1.7033

Abstract

Background: Irrational use of antibiotics can increase the resistance, so it is necessary to find alternative solutions by using herbals that have antibacterial activity, such as garlic which contains allicin, alliin, and sulfide derivatives, and red ginger which contains gingerol, flavonoids, and phenols. For traditional use, garlic and red ginger need to be extracted with aqueous solvents. Objective: Proving the antibacterial activity of the combination of garlic extract (Allium sativum) and red ginger extract (Zingiber officinale var. Rubrum) with aqueous solvents against Staphylococcus aureus. Methods: Each garlic extract and red ginger extract were made by the kinetic maceration with aqueous solvents, then mixed in a ratio of 1:1, 1:2, and 2:1. Results: The combination of garlic and red ginger extracts has strong antibacterial activity to inhibit the growth of Staphylococcus aureus. The average diameter of the inhibition zone at a ratio of 1:1, 1:2, and 2:1 was 30.40 mm, 24.51 mm, and 37.67 mm, respectively. The ANOVA test showed a P value of 0.000. Conclusion: The combination of garlic extract (Allium sativum) and red ginger extract (Zingiber officinale var. Rubrum) with aqueous solvent has strong antibacterial activity against Staphylococcus aureus, with the strongest combination at a ratio of 2:1.
UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN JERUK PURUT (Citrus hystrix D.C) Dengan DAUN SINGKONG (Manihot esculenta crantz) TERHADAP BAKTERI Staphylococcus aureus SECARA IN VITRO HASYIM, ANGGIE NOVTANIA; Triastuti, Nenny; Mochtar, Nur Mujadidah; Paramita, Ayu Lidya
JurnalMU: Jurnal Medis Umum Vol 2 No 2 (2025): JurnalMU: Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v2i2.25526

Abstract

Latar belakang : Penyakit infeksi bakteri merupakan penyebab penyakit paling umum yang dapat ditemukan di daerah tropis seperti negara Indonesia. Adanya faktor ekstrinsik dapat memudahkan mikroorganisme seperti bakteri, virus, jamur dan parasit untuk menyerang jaringan tubuh serta dapat berkembang dengan optimal. Salah satu bakteri gram positif yang paling umum menyebabkan infeksi salah satunya spesies Staphylococcus aureu. Daun jeruk purut dan daun singkong mengandung senyawa aktif flavonoid, minyak atsiri (sitronellal), saponin, tannin, fenolik, steroid dan alkaloid. Tujuan: Penelitian ini bertujuan untuk mengetahui adanya kombinasi ekstrak daun jeruk purut (Citrus hystrix D.C) dengan daun singkong (Manihot esculenta crantz) memiliki efektivitas yang sebanding atau lebih baik dibandingkan dengan antibiotik standar dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Metode : Daun jeruk dan daun singkong diekstraksi dengan metode maserasi pelarut etanol 70% kemudian dilakukan uji orientasi dan uji kombinasi antibakteri dengan metode difusi. Hasil : Hasil dikombinasi dengan perbandingan konsentrasi (1:1), (0,5:0,5), (1:0,5) dan (0,5:1). Data dianalisa secara statistic dengan uji Shapiro-wilk, homogenitas levene, dilanjutkan uji One-Way Anova dan Uji Post Hoc yakni Uji Tukey HSD. Hasil penelitian menunjukkan bahwa kombinasi ekstrak daun jeruk purut dan daun singkong memiliki aktivitas antibakteri terhadap Staphylococcus aureus. Kesimpulan: Kombinasi ekstrak paling efektif pada perbandingan konsentrasi 0,5:0,5 dengan rata-rata diameter zona hambat 11,33 mm.
Co-Authors Astri Dewayani Batsaikhan Saruuljavkhlan Dede Nasrullah Endraswari, Pepy HASYIM, ANGGIE NOVTANIA Ievani, Yelvi Indra Alfaray, Ricky Kamal Musthofa Kartika Afrida Fauzia Maya Rahmayanti Mochtar, Nur Mujadidah Mohammad Subkhan Muhamad Reza Utama Nenny Triastuti Ni Made Mertaniasih Nur Mujaddidah Mochtar Rahmat Sayyid Zharfan Rizka Aulia Rahma, Rizka Aulia Setiawan, Firman Syafarinah Nur Hidayah Akil Yelvi Levani