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The Effect of Oral Sildenafil on the Decrease in the Degree of Pulmonary Artery Systolic Pressure in PPHN Infants at Siti Khodijah Muhammadiyah Hospital Sepanjang Afif, Muhammad; Airlangga, Muhammad Perdana; Yuliyanasari, Nurma; Djalilah, Gina Noor
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 1 (2021): February
Publisher : APKKM (Muhammadiyah Medical and Health Education Association)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1786.194 KB) | DOI: 10.26714/magnamed.8.1.2021.18-28

Abstract

Background: Persistent Pulmonary Hypertension of the Newborn (PPHN) is a condition of the failure to decrease pulmonary artery pressure, so that blood pressure in the lungs remains high, as in a fetus. PPHN cases are 2-6 of 1000 live births and responsible for 10% of confirmed deaths in the neonatal intensive care unit (NICU). Sildenafil is vasodilator that can be used to reduce pulmonary artery systolic pressure (PASP), morbidity, and mortality in PPHN infants.Objective: To analyze the effect of sildenafil on decrease the severity of pulmonary artery systolic pressure in PPHN infants.Method: This is an analytic observational study with cross-sectional design. The samples were collected using consecutive sampling on 30 PPHN infant patients in 2018. The data were collected from medical records of PPHN infant patients, then assessing the severity value of PASP which obtained from echocardiography result. The severity of PASP is classified into normal (PASP≤35 mmHg), mild (PASP36-45 mmHg), moderate (PASP 45-60 mmHg), and severe (PASP>60 mmHg)Results: This study showed that 27 PPHN infant patients have decreased PASP level to normal, previously from mild 7 infants (23.3%), moderate 16 infants (53.3%), and severe 4 infants (13%), after being given oral sildenafil. There were 1 (3.3%) infant patient remained severes, 1 (3.3%) patient was decreased from severe to moderate, and 1 patient (3.3%) was decreased from severe to mild. The p value <0.05 was obtained, so oral sildenafil significantly decreased the PASP severity in PPHN infants patients.Conclusion: There is a beneficial effect of oral sildenafil on decreasing the severity of pulmonary artery systolic pressure in PPHN infants at the NICU of Siti Khodijah Muhammadiyah Hospital Sepanjang.
Global Burden Disease – Human Immunodeficiency Virus – Acquired Immune Deficiency Syndrome (HIV-AIDS) Nurma Yuliyanasari
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 1, No 01 (2017)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.948 KB)

Abstract

The Global Burden Disease /GBD menjadi suatu standar dari WHO sejak tahun 1990 untuk melaporkan informasi kesehatan global yang terkait dengan penyakit-penyakit lingkungan termasuk yang disebabkan oleh gangguan nutrisi dan komunikasi. Salah satu penyakit yang prevalensiya terus meningkat dan perlu mendapatkan perhatin serius dalam GBD adalah Acquired Immune Deficiency Syndrome (AIDS). Tujuan penulisan artikel ini adalah untuk memperluas wawasan tentang apa itu HIV-AIDS, penyebabnya, faktor resiko, epidemiologi dan prevalensinya, bagaimana mekanisme penurunan imunitas pada infeksi HIV, manifestasi klinis yang mungkin ditimbulkan, apa saja infeksi oportunistik penyebab kematian terbesar pada pasien yang terinfeksi virus HIV, dan jenis-jenis pemeriksaan untuk  mendeteksi HIV dan infeksi oportunistik. (QM 2017;01:65-77)
Association between gestational age and persistent pulmonary hypertension of the newborn (PPHN) severity in preterm babies at Sidoarjo Regional Hospital Aisyah Faadhilah; M. Perdana Airlangga; Nurma Yuliyanasari; Gina Noor Djalilah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.6107

Abstract

AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a condition that occurs due to increased resistance to blood vessels in the lungs that occur persistently after the baby is born. This can be attributed to congenital heart disease such as right-to-left shunts through foramen ovale (PFO) or patent ductus arteriosus (PDA) due to an error transition fetal blood circulation to the neonate. Although PPHN is always associated with births in post-term babies, PPHN cases are often found in preterm babies. Chances of babies born with PPHN are quite large, at 1.9% per 1000 live births. PPHN can be fatal, causing mortality rates ranging from 4 to 33%. The incidence of preterm births in Indonesia is estimated at 7-14%, around 459,200 - 900,000 babies per year. This study aimed to prove the relationship between premature babies and persistent pulmonary hypertension of the newborn (pphn) in Sidoarjo  Regional Hospital and to know the characteristics and analyze these variables.  This research used crossed sectional studied design; the population was all preterm babies in the NICU at Sidoarjo  regional hospital. All samples are from medical records in January-December 2018. There is a significant difference between preterm babies and PPHN (p < 0.05); besides, the results from Spearman's correlation analysis obtained a correlation coefficient (ρ) = 0.485. In the cross-tabulation analysis, the result of the proportion with the highest correlation was Late Preterm babies with severe PPHN of 46.7%. It can be concluded that there is a relationship between premature babies and PPHN in Sidoarjo  regional hospital..Keywords                      : Persistent pulmonary hypertension of the newborn, PPHN, Preterm BabiesCorrespondence            : aisyahhelmadevithalib@gmail.com
Pengaruh Siklus Kemoterapi terhadap Kualitas Hidup Pasien Kanker Payudara Menggunakan Eortc Qlq-C30 di RSUD Dr. Soetomo Surabaya Alshafiera Azayyana Mawadhani Sukma; Nurma Yuliyanasari; Tjatur Prijambodo; Nova Primadina
JURNAL IMPLEMENTA HUSADA Vol 1, No 2 (2020)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v1i2.4900

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Abstrak: Latar belakang: Pasien kanker payudara sering mengalami gangguan kualitas hidup. Kemoterapi adalah salah satu pilihan terapi yang memiliki banyak efek samping terhdap kualitas hidup pasien. Tujuan: Menjelaskan pengaruh kemoterapi terhadap kualitas hidup pasien kanker payudara yang diukur menggunakan EORTC QLQ-C30. Metode: Observasional analitik dengan desain cross sectional di RSUD Dr. Soetomo Surabaya. Subjek penelitian ini adalah pasien yang sedang menjalani kemoterapi pada siklus ke-3 sampai ke-6 yang memenuhi kriteria inklusi dan eksklusi dengan jumlah sampel adalah 67 responden. Pengumpulan data dilakukan dengan pemberian kuisioner EORTC QLQ-C30 serta data rekam medis. Uji statistik menggunakan uji alternatif Kruskal-Wallis. Hasil : Tidak terdapat pengaruh siklus kemoterapi terhadap kualitas hidup pasien kanker payudara pada domain fungsi, gejala, dan kesehatan umum (p>0.005). Kesimpulan : Tidak terdapat pengaruh siklus kemoterapi terhadap kualitas hidup pasien kanker payudara pada domain fungsi, gejala, dan kesehatan umum payudara di RSUD Dr. Soetomo Surabaya yang diukur menggunakan kuisioner EORTC QLQ-C30.
Efektivitas Biaya Sacubitril / Valsartan dalam Mengurangi Rehospitaliasasi pada Pengobatan Gagal Jantung dengan Fraksi Ejeksi Berkurang Dibandingkan dengan Penggunaan Obat Golongan Ace Inhibitor Kharisma Sukma Nanda; Muhammad Perdana Airlangga; Nurma Yuliyanasari; Yudith Annisa Ayu Rezkitha
JURNAL IMPLEMENTA HUSADA Vol 2, No 1 (2021)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v2i1.6950

Abstract

Gagal jantung merupakan masalah kesehatan masyarakat  dengan angka morbiditas dan mortalitas yang cukup besar, serta risiko kematian yang tinggi  pada negara maju maupun negara berkembang, sehingga membutuhkan manajemen terapi yang tepat untuk mengurangi morbiditas dan mortalitas. ACEI / ARB adalah standar perawatan yang biasa digunakan selama ini, namun sacubitril / valsartan banyak dibicarakan dan memberikan resiko kematian yang lebih rendah serta mengurangi rehospitalisasi pada pasien gagal jantung dibandingkan dengan penggunaan ACEI. Oleh karena itu, sacubitril / valsartan cenderung lebih hemat biaya dibandingkan dengan ACEI (standar perawatan saat ini). Tujuan penulisan ini untuk mengetahui efektivitas biaya sacubitril / valsartan dibandingkan dengan enalapril (ACEI) dalam pengobatan gagal jantung dengan fraksi ejeksi berkurang.
FNAB and Anatomic Pathology Biopsy Accuracy in Thyroid Nodule Diagnosis Muhammad Tegar Nugraha; Yohni Wahyu Finansah; Nova Primadina; Nurma Yuliyanasari
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 1 (2022): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.1.2022.10-16

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Background: The problem examined in this study is the accuracy of the FNAB examination compared to the gold standard histopathology.Objective: To determine the value of sensitivity, specificity, positive and negative predictive values , and the accuracy of the FNABMethod: This study uses a retrospective method. The population was patients with thyroid nodules in Pare Regional Hospital, Kediri, in 2015-2019. The sampling technique is Simple Random Sampling Probability. The sample was the patients who had been diagnosed with thyroid nodules and underwent FNAB examination followed by histopathology biopsy. The instrument used was secondary data collection inpatient medical record data. The data can be processed through diagnostic tests.Results: FNAB sensitivity value of 66.6%, a specificity value of 97%, a positive predictive value of 90.9%, and a negative predictive value of 86.8%, and an accuracy rate of 87.7%Conclusion: FNAB can be used as a first-line examination in diagnosing thyroid nodules but cannot replace histopathological examination as a gold standard.
Potensi Kejadian Burnout pada Mahasiswa Kedokteran di Masa Pandemi Covid-19 AHMAD FIRDAUS; NURMA YULIYANASARI; GINA NOOR DJALILLAH; MUHAMMAD REZA UTAMA
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v18i2.117

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Abstract Covid-19 pandemic has caused universal psychosocial repercussions and mass hysteria among the society and various sectors, including education sector. The online learning or distance learning applied during the pandemic has worsened the stress experienced by medical students. The stress level increased due to gaps in access to learning and excessive assignments given without considering students’ cognitive, affective, and psychomotor domains. Continuous academic stress in the long term would bring negative impacts, leading to lower learning motivation and burnout syndrome. The quality of social relationship has been known to significantly affect anxiety level. Therefore, cooperation from family, community, academic institutions, and government agencies in providing social attention and support is needed. In addition, intrinsic preventions through the improvement of lifestyle, health-related behaviour, religious approaches (The Psychology of Religion), motivation, and self-resilience are also important to avoid burnout syndrome among medical students. This study was conducted to propose insights that are expected helpful in anticipating, preventing and minimizing the occurrence of burnout syndrome which would lead to maladaptive behaviours among medical students
THE RELATIONSHIP BETWEEN SUBMANDIBULAR ABSCESS AND ODONTOGENIC INFECTION AT SITI KHADIJAH HOSPITAL DURING THE PERIOD JANUARY 2016 – NOVEMBER 2021 Andi Fikri Agussalim; Yohni Wahyu Finansah; Yuli Wahyu Rahmawati; Brilliant Citra Wirashada; Nurma Yuliyanasari
Jurnal Scientia Vol. 12 No. 01 (2023): Education, Sosial science and Planning technique
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/scientia.v12i01.1260

Abstract

Submandibular abscess is an inflammation and is accompanied by pus formation in the submandibular region and there are clinical symptoms in the form of sore throat, fever and limited movement of opening the mouth. Submandibular abscess is included in one of the odontogenic abscesses that are often found, cases increase in the transition season when the human body's immunity decreases causing the body to be less able to fight bacteria, this abscess comes from premolars or molars a lower jaw that spreads in a lingual direction below m. Mylohyoid. Knowing the relationship between submandibular abscesses and odontogenic infections. This type of study is observational using the cross sectional method in hospitals. Siti Khadija Throughout. Samples are selected by consecutive sampling. Data collection of submandibular abscesses and odontogenic infections were taken from medical records. The results of the medical record were analyzed with the Spearman correlation analysis test. Theistic characteristics of submandibular abscess patients at Siti Khodijah Muhammadiyah Hospital Branch Along Sidoarjo that were observed in this study were gender, age, occupation, length of treatment, comorbidities, complications and management. There was no significant association between age with submandibular abscesses and sex with submandibular abscesses (p > 0.05). The largest types of odontogenic infections in the study were cellulitis and mouth abscesses (86.5%). There was a significant association between submandibular abscess and odontogenic infection with the contingency correlation test (p<0.05) and with the Spearman correlation test (p<0.05). There is a significant association between submandibular abscesses and odontogenic infections.
Hubungan Intensitas Aktivitas Fisik dengan Tingkat Stres pada Mahasiswa Program Studi Pendidikan Dokter FK UM Surabaya Aryantara, Arif Rachman; Levani, Yelvi; Prahasanti, Kartika; Yuliyanasari, Nurma
Medica Arteriana (Med-Art) Vol 5, No 2 (2023): Desember 2023
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/medart.5.2.2023.37-43

Abstract

Latar Belakang: Mahasiswa kedokteran memiliki tingkat stres yang tinggi. Rendahnya intensitas aktivitas fisik menjadi salah satu pemicunya. Maha-siswa mendengarkan perkuliahan dari pagi sampai sore dalam posisi yang sama yaitu duduk. Sehingga mahasiswa memiliki intensitas aktivitas fisik sedentary. Penelitian ini dilakukan untuk mengetahui apakah terdapat hubungan intensitas aktivitas fisik dengan tingkat stres pada mahasiswa program studi pendidikan dokter FK UM SurabayaMetode: Penelitian dilakukan dengan metode analitik observasional dengan desain penelitian cross sectional. Sampel sebesar 75 sampel. Pengambilan sampel secara simple random sampling. Pengukuran intensitas aktivitas fisik menggunakan kuisoner International Physical Activity Queistionnaire (IPAQ). Pada tingkat stres pengukuran menggunakan kuisioner Depression Anxiety Stress Scale 21 (DASS-21). Analisis data mengguanakan analisis SpearmanHasil: Hasil penelitian menunjukkan adanya hubungan intensitas aktivitas fisik dengan tingkat stres dengan nilai signifikansi sebsar 0,000. Yang mana tingkat signifikansi <0,05 memiliki korelasi cukup. Nilai korelasi didapatkan sebesar -0,517. Hal ini menunjukkan adanya korelasi negatif yang kuat dimana intensitas fisik memiliki hubungan terbalik dengan tingkat stres.Kesimpulan: Dari penelitian ini dapat disimpulkan bahwa terdapat hubungan berlawanan yang siginifikan antara intensitas aktivitas fisik dengan tingkat stress. Semakin tinggi tingkat intensitas aktivitas fisik, maka semakin rendah tingkat stress yang dialami mahasiswa kedokteran.
Perbedaan Tingkat Kecemasan pada Mahasiswa Semester Dua dan Delapan Program Studi S1 Keperawatan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Surabaya Berdasarkan Beck Anxiety Inventory (BAI) Syarlita, Alethia Zahrah; Yuliyanasari, Nurma; Prijambodo, Tjatur; Subagyo, Roni
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 7, No 1 (2020): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.259 KB) | DOI: 10.26714/magnamed.7.1.2020.1-7

Abstract

Differences in Anxiety Levels in Second and Eighth Semester Students of Undergraduate Nursing Study Programs, Faculty of Health Sciences, the University of Muhammadiyah Surabaya Based on Beck Anxiety Inventory (BAI)Latar belakang: Kecemasan pada mahasiswa, khususnya pada mahasiswa fakultas kesehatan dapat mempengaruhi kinerja perkuliahan maupun saat berhadapan langsung dengan pasien nantinya, sehingga hal tersebut membutuhkan perhatian lebih. Mahasiswa semester dua, dan mahasiswa semester delapan tentu memiliki masalah yang berbeda pada saat perkuliahan.Tujuan: Untuk mengetahui ada tidaknya perbedaan tingkat kecemasan antar mahasiswa program studi S1 Keperawatan semester dua dan mahasiswa semester delapan Fakultas Ilmu Kesehatan UM SurabayaMetode: Penelitian cross-sectional, dan populasinya adalah seluruh mahasiswa semester dua dan delapan program studi S1 keperawatan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Surabaya. Teknik pengambilan sampel dalam penelitian ini adalah Consecutive sampling, dengan Sampel mahasiswa semester dua dan delapan program studi S1 keperawatan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Surabaya dengan kriteria inklusi sebagai mahasiswa aktif dan bersedia berpartisipasi dalam penelitian ini. Instrumen yang digunakan adalah dengan kuesioner identitas dan BAI (Beck Anxiety Inventory). Penelitian ini menggunakan teknik analisa statistik menggunakan teknik analisis statistic Chi Square.Hasil: Rata-rata skor kecemasan mahasiswa semester dua sebesar 18,068 dengan simpangan baku sebesar 9,954. Sedangkan mahasiswa semester delapan memiliki rata-rata skor kecemasan sebesar 14,397 dengan simpangan baku sebesar 10,307. Hasil analisis dengan uji chisquare menunjukkan nilai signifikansi sebesar 0,033.Simpulan: Terdapat perbedaan yang signifikan pada tingkat kecemasan mahasiswa semester dua dan mahasiswa semester delapan program studi S1 Keperawatan UM Surabaya. Background: Anxiety in students, especially in health faculty students, can affect lecture performance and, when dealing directly with patients later, require more attention. Second-semester students and eighth-semester students certainly have different problems during lectures.Objective: To determine whether there is a difference in the level of anxiety between students of the second semester of the undergraduate nursing study program and students of the eighth semester of the Faculty of Health Sciences, the University of Muhammadiyah SurabayaMethods: This is a cross-sectional study, and the population is all second-semester students and eight undergraduate nursing study programs, Faculty of Health Sciences, University of Muhammadiyah Surabaya. The sampling technique in this study was Consecutive sampling, with a sample of second-semester students and eight undergraduate nursing study programs at the Faculty of Health Sciences, the University of Muhammadiyah Surabaya, with inclusion criteria as active students and willing to participate in this study. The instruments used are identity questionnaires and BAI (Beck Anxiety Inventory). This study uses statistical analysis techniques using Chi-Square statistical analysis techniques.Results: The average score of second-semester students' anxiety was 18.068, with a standard deviation of 9.954. In contrast, the eighth-semester students have an average anxiety score of 14,397 with a standard deviation of 10,307. The analysis results with the chi-square test showed a significance value of 0.033.Conclusion: There is a significant difference in the level of anxiety of second-semester students and eighth-semester students of the undergraduate Nursing study program at the University of Muhammadiyah Surabaya.