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All Journal Biomedical Journal of Indonesia Journal of General-Procedural Dermatology & Venereology Indonesia
Yosi, Ariyati
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Correlation Between Serum 25 Hydroxy-vitamin D Levels and The Worst Pain Intensity in Postherpetic Neuralgia Mellaratna, Wizar Putri; Jusuf, Nelva K; Yosi, Ariyati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 6, No. 2
Publisher : UI Scholars Hub

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Background: Postherpetic neuralgia (PHN) is persistent pain in the affected dermatome that occurs more than three months after the eruption of the herpes zoster has disappeared. Vitamin D has a role in Schwann cell regeneration and stimulates the release of nerve growth factors. Methods: Blood sampling was performed to test serum 25(OH)D levels. Patients filled out their worst pain intensity using the Zoster Brief Pain Inventory questionnaire. The score was reported in Likert score (0-10), 0 indicating no pain and 10 indicating the most severe pain. Spearman correlation test was used, and p 0.05) and PHN durations (p >0.05). However, there were significant differences in serum 25(OH)D levels between sex groups (p Conclusion: No correlation exists between serum 25(OH)D levels and the worst pain intensity in PHN patients. Further research with a control group, liver function tests, and the duration of sun exposure data is needed to conclude the role of 25(OH)D in PHN patients.
The use of systemic medications in pediatric dermatoses: A review Narla, Shanthi; Rahmayunita, Githa; Astriningrum, Rinadewi; Shwayder, Tor; Yosi, Ariyati; Lim, Henry W.
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 4, No. 1
Publisher : UI Scholars Hub

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Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppurativa) despite not having extensive randomized clinical trials. The purpose of this article is to summarize the available data on the treatment regiments, safety, and efficacy of systemic immunosuppressants, including the newer biologics, focusing on the most up-to-date systematic reviews or randomized clinical trials. The review demonstrates that many of the present studies lack data on long-term efficacy and consist of small patient populations. Further research into the long-term safety of these systemic medications is of vital importance especially due to the chronic nature of most pediatric dermatological conditions that require the use of systemic agents.
The management of seborrheic dermatitis 2020 Widaty, Sandra; Bramono, Kusmarinah; Listiawan, Muhammad Yulianto; Yosi, Ariyati; Miranda, Eliza; Rahmayunita, Githa; Brahmanti, Herwinda; Lim, Henry W
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 1
Publisher : UI Scholars Hub

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Background: Seborrheic dermatitis (SD) is a chronic relapsing dermatitis manifesting in the seborrheic area, affecting infants or adults. In Indonesia, the prevalence of SD is 0.99–5.8% of all dermatology cases from 2013 to 2015. SD has been known to be a prominent manifestation among HIV patients, but there is an increasing trend in the general population. Therefore, in 2017, the Indonesian Society for Dermatology and Venereology proposed a consensus for the management of SD in Indonesia based on the discussion from 12 dermatological centers. Concurrent with the development of new drugs, this study aims to evaluate and develop a guideline for the treatment of seborrheic dermatitis in Indonesia to update the previous guidelines in 2017. Methods: Systematic review was based on evidence-based methods, and scientific evidences were acquired through systematic search. Evidence analysis was in accordance with the level of evidence. The available evidences were evaluated, and conclusion was based on the grade of recommendation. Critical appraisal was conducted by experts in dermatology and venereology. Results: Severity of SD can be determined by using the Seborrheic Dermatitis Area Severity Index. The principle of scalp SD management is controlling the scalp condition in a cost-effective manner to make patients comfortable. The recommendations for treatment of adult SD are topical agents, such as antifungals, nonsteroidal anti-inflammatory agents with antifungal properties, corticosteroids, and calcineurin inhibitors. Conclusion: We have updated and added newer agents for the treatment of SD. The approach is divided into scalp or nonscalp and also adult or infantile SD.
Plasma malondialdehyde levels related to acne vulgaris severity Puspita, Fitri; Jusuf, Nelva Karmila; Yosi, Ariyati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 3
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Background: Acne vulgaris (AV) is a multifactorial disorder characterized by the formation of open and closed comedones, papules, pustules, nodules, and cysts. Oxidative stress plays a role in the pathogenesis of AV. Reactive Oxygen Species (ROS), especially lipid peroxides (LPO), plays a role in mediating acne inflammation. Malondialdehyde (MDA) is one of the byproducts of LPO commonly used as a biomarker of cell damage.Methods: This cross-sectional analytic study consisted of sixty patients with AV. The samples were taken from the blood plasma of AV subjects. An enzyme-linked immunosorbent assay (ELISA) examination was performed. The normality of data distribution was determined using the Kolmogorov-Smirnov test and the differences of plasma MDA levels based on the severity of AV were determined using the Kruskal-Wallis test. P valueResults: Acne vulgaris was predominantly found in women (70%), age group of 18 – 25 years old (73,33%), and patients with family history of AV (61,67%). Higher plasma MDA levels were found in women [5,5 (2,53 – 77,6) nmol/mL], age group of 26 – 35 years [5,66 (2,73 – 25) nmol/mL], and subjects with family history of AV [5,49 (2,53 – 77,6) nmol/mL]. Based on the severity of AV, the severe AV group had highest plasma MDA [13,85 (2,69 – 77,6) nmol/mL], followed by moderate AV group [4,46 (2,53-14,3) nmol/mL] and mild AV [3,78 (2,47-6,88) nmol/mL]. There were differences in plasma MDA level based on the severity of AV (p<0,001).Conclusion: There were differences in plasma MDA levels based on the severity of AV.
Dermatological Infectious Diseases Prevalence at Dermatology-Venereology Outpatient Clinics of Hospitals in Medan Yosi, Ariyati; Fujiati, Isti Ilmi; Yulfi, Hemma; Nasution, Irina Kemala
Biomedical Journal of Indonesia Vol. 11 No. 2 (2025): Vol 11, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i2.248

Abstract

Introduction. Skin infections are common in developing countries but are often not considered a significant health problem. One cause of this condition is a lack of epidemiological information about the prevalence and/or severity of the disease. This study aims to determine the prevalence and proportion of infectious skin diseases based on gender and age in the teaching hospitals at the Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. Methods. A descriptive-retrospective method was used in this study and the data were obtained from the medical records of patients at the dermatology and venereology polyclinic at Adam Malik Hospital and Prof. Dr. Chairuddin P. Lubis Universitas Sumatera Utara Hospitaletween 2017 and 2019. Results. A total of 12,686 patients were enrolled in this study, 26% were diagnosed with infectious skin disease with a total of 3,297 cases. Based on gender, patients were more dominated by men (55%) than women (45%). Most patients with infectious skin diseases were in the late adolescent age group or 17–25 years (20.4%) and the least were in the 0–4 years age group (3.2%). Furthermore, fungi were the dominant causative agent, which accounts for 51.5% of all cases. Conclusion. Infectious skin disease is a skin disease that is often found, especially in men and the age group of 17–25 years.
Co-Authors Astriningrum, Rinadewi Fitri Puspita Fujiati, Isti Ilmi Githa Rahmayunita Herwinda Brahmanti Jusuf, Nelva K Jusuf, Nelva Karmila Kusmarinah Bramono Lim, Henry W Lim, Henry W. M. Yulianto Listiawan Miranda, Eliza Narla, Shanthi Nasution, Irina Kemala Sandra Widaty Shwayder, Tor Wizar Putri Mellaratna Yulfi, Hemma