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Blastocytosis hominis: Unboxing Its Clinical Significance Rozi, Muhammad Fakhrur; Darlan, Dewi Masyithah
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.068 KB) | DOI: 10.32734/sumej.v2i2.724

Abstract

Abstract. Blastocystis hominisis a unicellular parasite classified as stramenopiles found in human and other mammals. The prevalence varies depending on the region, higher in developing country. The organism is transmitted via fecal-oral route by ingestion of oocyst contaminated food or water. Travelers also have high-risk of having blastocytstis infection. Based on recent studies, several proposed virulence factor are also identified but it remains elusive. The advanced technique has been used to describe its genetic variation and diversity that might be related to its clinical significance. There are 6 distinct morphological forms of Blastocystis including vacuolar, granular, ameboid, and cystic form. The cystic form is considered as an infective form of the organism. Exposure to animals is suggested as the other transmission route, consequently, the infection is also considered as zoonotic infection. It can produce broad clinical manifestation ranging from asymptomatic, self-limiting diarrhea until severe watery diarrhea, depends on host factors and the organism subtype. The organism can produce pruritus and urticaria, proved in literature. Since its pathogenicity remains unclear, conservative management is still suggested to all asymptomatic-symptomatic blastocytosis patients in accordance to patient’s immune status.
Daily Soy–Catfish–Anchovy–Rice (SCAR) Porridge Increases 25(OH)D Serum Levels in Tuberculosis Patients with Vitamin D Receptor Gene Polymorphisms Dina Keumala Sari; Ridha Dharmajaya; Mutiara Indah Sari; Dewi Masyithah Darlan
The Indonesian Biomedical Journal Vol 13, No 4 (2021)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v13i4.1725

Abstract

BACKGROUND: The presence of vitamin D receptor (VDR) polymorphism and high levels of inflammatory markers are predisposing factors indicating disease progression and malnutrition. To meet nutritional needs in maintaining nutritional status in tuberculosis patients with VDR gene polymorphisms (TaqI or FokI), food that is easily absorbed and high in vitamin D, calcium, and protein is needed. This study was conducted to determine whether high vitamin D and calcium porridge called soy–catfish–anchovy–rice (SCAR) porridge would increase 25(OH)D serum levels and other parameters, including calcium, albumin, high-sensivity C-reactive protein (hs-CRP), and blood glucose serum levels.METHODS: The study was a parallel, open, clinical trial. There were 22 subjects in the intervention (I) group who received 50 g of SCAR porridge once per day along with dietary counseling, and 21 subjects in the control (C) group who only received dietary counseling. All subjects with TC and CC (TaqI) or TC and CC (FokI) genotype were included in this study. The intervention lasted for 14 days, and the parameters such as 25(OH)D, calcium, albumin, hs-CRP, and blood glucose serum levels were assessed before and after intervention between groups.RESULTS: All subjects in both groups completed the study. After 14 days of intervention, there was a significant increase in 25(OH)D (p=0.01) and decrease in hs-CRP (p=0.02) serum levels in the I group, and no change was observed in the C group. There was no significant difference in albumin and blood glucose serum levels.CONCLUSION: The results show that 50 g of SCAR porridge per day for 14 days is an effective supplementation that can increase 25(OH)D and decrease hs-CRP serum levels in tuberculosis patients with VDR gene polymorphism.KEYWORDS: vitamin D, hs-CRP, polymorphism, porridge
Knowledge level, Attitude, and Behavior Regarding Toxoplasmosis Among Medical Students of Universitas Sumatera Utara Maurin, Ajeng Putri; Darlan, Dewi Masyithah
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.7169

Abstract

Toxoplasmosis is an infection caused by a single-celled parasite calledToxoplasma gondii.Toxoplasma gondiican infect almost all warm-blooded animals and humans. Toxoplasmosis is still prevalent worldwide, particularly in tropical countries including Indonesia. Various factors contribute to the prevalence, involving a lack of knowledge, attitude, and behaviour towards toxoplasmosis. This study was aimed to determine knowledge level, attitude, and behaviour on toxoplasmosis among medical students of Universitas Sumatera Utara. This was an analytical study with across-sectionaldesign. Data collection was conducted using a questionnaire instrument. The consecutive sampling method was used to enroll the subjects from medical students of Universitas Sumatera Utara class year of 2017-2020 who met the inclusion and exclution criteria. The results showed that, based on gender, the p-value of the knowledge, attitude, and behaviour were 0.72, 0.02, and 0.285, respectively. Based on the age, the p-value of the knowledge, attitude, and behaviour were 0.013, 0.141, and 0.405. According to the class year, the p-value of the knowledge, attitude, and behaviour were 0,006, 0,138, and 0,919. This results indicated a significant difference in attitude (based on gender) and knowledge level (based on age and the class year).
Knowledge level regarding Risk Factors of Acanthamoeba Keratitis in Contact Lens Users and the Relation to Student Characteristics of Faculty Medicine of University of Sumatera Utara Subrata, Harith Naufal; Darlan, Dewi Masyithah
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.7168

Abstract

Acanthamoeba Keratitisis an infection of cornea caused by one of free living amoeba group,Acanthamoeba spp. The most common risk factor ofAcanthamoeba Keratitisis the usage of contact lens. The purpose of this study is to assess knowledge level regarding risk factor forAcanthamoeba keratitisin contact lens users and its relation to student characteristics in Faculty Medicine of University of Sumatera Utara (FMUSU). This study is an analytical study withcross sectionaldesign. Data collection method was carried out by a questionnaire based survey. The study sample was selected by stratified proportional sampling method from FMUSU students with entry year of 2017-2020 that meets study criteria. Number of respondents of this study is 100 students. Univariate analysis showed knowledge level of respondents are 63% high, 34% medium, and 3% low. Bivariate analysis with Fishers Exact test showed there is no significant relation between sex with knowledge level regarding risk factor forAcanthamoeba Keratitisin contact lens users (C:0,068, X2:0,559, p:0,873) and there is significant relation between entry year with knowledge level regarding risk factor forAcanthamoeba Keratitisin contact lens users (C:0,312, X2:10,372, p:0,002).
PEMETAAN DAN PENANGGULANAN PENDERITA SINDROMA METABOLIK DI KECAMATAN MEDAN AREA KOTA MEDAN: MAPPING AND HANDLING OF METABOLIC SYNDRO ME PATIENTS IN MEDAN AREA DISTRICT, MEDAN CITY Pratama, Arief; Rambe, Aldy Safruddin; Widyawati, Tri; Darlan, Dewi Masyithah; Sembiring, Rosita Juwita
Jurnal Kedokteran Ibnu Nafis Vol. 14 No. 1 (2025): Juni 2025
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/jkin.v14i1.796

Abstract

Sindroma metabolik merupakan salah satu masalah kesehatan utama yang terus meningkat prevalensinya di Indonesia, termasuk di Sumatera Utara. Penelitian ini bertujuan untuk memetakan prevalensi dan faktor risiko sindroma metabolik di Kecamatan Medan Area, Kota Medan, melalui program pengabdian masyarakat. Metode pelaksanaan meliputi edukasi kesehatan, skrining fisik, dan pengukuran parameter laboratorium seperti gula darah dan kolesterol pada 150 peserta dengan usia rata-rata 45 tahun. Hasil menunjukkan bahwa 38% peserta memenuhi kriteria sindroma metabolik, dengan prevalensi obesitas abdominal sebesar 60%, hipertensi 45%, hiperglikemia 30%, dan hiperkolesterolemia 40%. Menyoroti pentingnya intervensi promotif dan preventif berbasis komunitas untuk menurunkan risiko sindroma metabolik. Data ini diharapkan menjadi dasar pengembangan kebijakan kesehatan di tingkat lokal dan regional.
Ent Examination and Cerumen Removal in Letjen Jamin Ginting Junior High School, Berastagi Farhat, Farhat; Daulay, Elvita Rahmi; Darlan, Dewi Masyithah
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (332.25 KB) | DOI: 10.32734/abdimastalenta.v4i2.2814

Abstract

Diseases of ear, nose, and throat (ENT) are common diseases in the world. The diseases are essential due to morbidities, which affect the physiological functions in the head and neck region. Cerumen impaction is the most common finding disease of ENT in children. The community service was done to find the distribution of ear, nose, and throat examination results of students in Letjen Jamin Ginting Junior High School, Berastagi, especially cerumen impaction which then were treated with cerumen removal. The community service also aimed to increase student's knowledge about ENT disease. The ENT examination was done to 188 students. The students with cerumen impaction were treated with cerumen removal. The students also educated about ENT disease to improve knowledge about ENT disease. Among 188 students, the number of male students was more than female with 98 students (52.1%), where 76 students (40.4%) were 14 years old. 150 students (79.8%) did not have any complaint about their ear, nose, and throat. Ear fullness was a common chief complaint from the students with 15 students (8.0%). Ear disease was a frequent disease with 44 students (47.3%) and cerumen impaction as the most common findings with 43 students (22.9%). In ENT disease education, the evaluation was done with the highest result was get by 8 students with 80% corrected answers. Ear disease had high prevalence with cerumen impaction as the most common findings of ENT examination.
Pemanfaatan Daun Sirsak (Annona muricata) sebagai Sampo Anti Kutu Kepala (Pediculus humanus capitis) Samosir, Fauzan Azmi Hasti Habibi; Darlan, Dewi Masyithah; Nasution, Luthfi Umam Hakim; Panggabean, Grestia Angraini
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 1 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i1.10530

Abstract

ABSTRAK Latar Belakang: Salah satu masalah yang sering timbul pada kulit kepala adalah pedikulosis kapitis yang disebabkan oleh kutu kepala (Pediculus humanus capitis). Kutu kepala ini akan membuat kepala terasa gatal sehingga terus-menerus menggaruk. Lama-kelamaan, garukan tersebut akan membuat kulit kepala terkelupas sehingga memicu timbulnya masalah lainnya yang bersifat lokal maupun sistemik terutama pada anak dan perempuan. Walaupun kecil, kutu kepala sangat berbahaya, karena hidup dengan menghisap darah dari kulit kepala dan menular dengan mudah ke berbagai tempat, seperti ke bantal, guling, hingga ke kepala manusia. Salah satu cara mengatasi kutu kepala adalah dengan menggunakan pedikulosida sintetis yang mudah didapat di apotek. Tujuan: Untuk mengetahui efektifitas penggunaan sampo dari daun sirsak dalam membasmi kutu kepala. Metode: Penelitian ini merupakan penelitian eksperimental dengan menggunakan kutu kepala sebanyak 72 ekor dengan 3 kali replikasi. Kelompok uji terdiri dari kelompok P1 dengan konsentrasi larutan daun sirsak 15% dan kelompok P2 10%. Sampo P1 dan P2 masing-masing dilakukan pengenceran dengan air dengan perbandingan sampo:air, yaitu 1:1 dan 1:2. Hasil: Waktu yang diperlukan untuk mematikan kutu kepala pada kelompok P1 dengan waktu rata-rata 11 detik pada pengujian sampo:air (1:1) dan 11,67 detik pada (1:2). Adapun kelompok P2 pada pengujian sampo:air (1:1) dalam waktu 12 detik dan 12,33 detik pada (1:2). Persentase mortalitas kutu kepala pada keseluruhan kelompok uji adalah 100% dan pada P2 ratarata 12 detik dengan persentase mortalitas 100%. Kesimpulan: Sampo dari daun sirsak efektif dalam membasmi kutu kepala. Kata Kunci: daun sirsak, kutu kepala, pedikulosis kapitis, sampo   ABSTRACT Background: One problem that often arises on the scalp is pediculosis capitis caused by head lice (Pediculus humanus capitis). These head lice will make your head itch and scratching constantly. Over time, the scratching will exfoliate the scalp, triggering other local and systemic problems, especially in children and women. Although small, head lice are very dangerous, because they live by sucking blood from the scalp and spread easily to various places, such as pillows, bolsters, up to the human head. One way to deal with head lice is to use synthetic pediculicides which are easy to get at pharmacies. Objectives: To find out the effectiveness of using soursop leaf shampoo in eradicating hair nails. Methods: This study was an experimental study using 72 head lice with 3 replications. The test group consisted of group P1 with a concentration of 15% soursop leaf solution and group P2 10%. Each of the P1 and P2 shampoos was diluted with water with a shampoo:water ratio, namely 1:1 and 1:2. Results: The time needed to kill head lice in group P1 was 11 seconds on the shampoo:water (1:1) test and 11.67 seconds on (1:2) average. As for the P2 group in the shampoo:water test (1:1) in 12 seconds and 12.33 seconds in (1:2). The percentage of head lice mortality in the entire test group was 100% and at P2 an average of 12 seconds with a mortality rate of 100%. Conclusion: Soursop leaf shampoo is effective in eradicating head lice. Keywords: head lice, pediculosis capitis, shampoo, soursop leaf