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THE DESCRIPTION OF HISTOPATHOLOGY IN BREAST CANCER PATIENTS AT RSUP.H. ADAM MALIK MEDAN Siregar, Ice Ratnalela
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol 13 No 1 (2018): Jurnal Ilmiah PANNMED Periode Mei-Agustus 2018
Publisher : Politeknik Kesehatan Kemetrian Kesehatan Medan

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Breasts are an important organ for women. Breasts can experience various disorders or diseases, bothserious and mild disease. Among these are breast cancer which is one of the most dreaded breastabnormalities. Breast cancer is a cancer that comes from the gland, glandular, and breast supporttissue.Breast cancer has been known to attack only women. In fact, malignant tumors are also biased alsoagainst men. The histopathologic feature is a diagnostic feature of breast cancer. The purpose of this studywas to determine the histopathologic description of Breast Cancer at RSUP.H.Adam Malik. The sample inthis study is all breast cancer patients who have been diagnosed by doctors who visit the RSUP.H.AdamMalik (Population). The research method used is descriptive of taking secondary data in medical record atRSU.H.Adam Malik. The results of this study can be seen that of 60 breast cancer patients who do biopsy,the majority of patients have histopathology of breast cancer invasive Ductal Carcinoma as much as 31people (51.66%) and Invasive Breast Cancer Nos Type of 29 people (48.34%).

PEMERIKSAAN BADAN KETON PADA URINE PENDERITA DIABETES MELLITUS TIPE II (NIDDM) YANG DI RAWAT INAP DI RSUP H. ADAM MALIK MEDAN Siregar, Ice Ratnalela
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol 8 No 3 (2014): Jurnal Ilmiah PANNMED Periode Januari-April 2014
Publisher : Politeknik Kesehatan Kemetrian Kesehatan Medan

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Diabetes mellitus merupakan gangguan metabolisme dari distribusi gula oleh tubuh. Penderitadiabetes tidak bisa memproduksi insulin dalam jumlah yang cukup, atau tidak mampu menggunakaninsulin secara efektif, sehingga terjadi kelebihan gula dalam darah. Kelebihan gula yang kronis dalamdarah ( hiperglikemia) ini menjadi racun dalam tubuh. Sebagian glukosa yang bertahan di dalam darahitu melimpah ke system urin untuk di buang melalaui urin. Pada tubuh yang sehat pancreas melepashormone insulin yang bertugas mengangkut gula melalui darah ke otot-otot dan jaringan lain untukmemasok energi. Pencetus utama Diabetes mellitus tipe II dapat di sebut karena factor obesitas ataukegemukan dan factor lain adalah adalah pola makan yang salah, proses penuaan, dan stress yangmengakibatkan terjadinya resistensi insulin. Kelompok diabetes mellitus tipe II dapat mengalaiketoasiosis, tetapi hal ini jarang terjadi.Ketoasidosis terjadi karena tidak adanya insulin yang dihasilkan. Akibat dari defisiensi insulin yang lain adalah pemecahan lemak menjadi asam-asam lemakbebas dan gliserol. Asam-asam lemak bebas akan di ubah menjadi badan keton oleh hati. Badanketone bersifat asam dan bila bertumpuk dalam sirkulasi darah badan keton akan menimbulkanketoasidosis diabetic. Ketoasidosis diabetic adalah komplikasi akut diabetes mellitus yang serius danharus segera ditangani. Ketoasidosis diabetic memerlukan penanganan yang cepat dan tepatmengingat angka kematian yang tinggi. Pemeriksaan badan ketone pada urin penderita diabetesmellitus di lakukan di laboratorium. Telah di lakukan pemeriksaan badan ketone pada urine penderitadiabetes mellitus tipe II yang di rawat inap di RSUP H Adam Malik Medan dengan sampel urine segaryang di laksanakan di laboratorium politeknik Kesehatan Jurusan Analis Kesehatan Medan padatanggal 12-16 juli 2010 terhadap 20 orang pasien baik pria atau wanita. Dari hasil penelitiandiperolehkesimpulan bahwa pada saat melakukan penelitian tidak di temukan badan ketone pada urinpenderita diabetes mellitus.

DESCRIPTION OF THE RESULT OF RHEUMATOID FACTOR IN MENOPAUSAL WOMEN IN SIDORAME BARAT II VILAGE ZONE VI MEDAN PERJUANGAN DISTRICT Siregar, Ice Ratnalela
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol 13 No 3 (2019): Jurnal Ilmiah PANNMED Periode Januari-April 2019
Publisher : Politeknik Kesehatan Kemetrian Kesehatan Medan

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Menopause is a condition that occur in women with thedecreasing hormone who affect on menstruationcycle to the lower level that make the menstruation can not happend again. Decreasing hormon can be oneof the triggers of Rheumatoid Arthritis that caused by decreasing the imunity who make an autoimunereaction. One of the checks that can be a reference tho detect the Rheumatoid Arthritis is RheumatoidFactor. Rheumtaoid Factor using aglutination principle between sheep erythrochytes which been fixedwith human sera. The type of research that has been used is descriptive with 26 samples who get fromlemeshow formula. Sera used as the material and research held at imuno-serology’s LaboratoriumPolytechnic of Health, Health Analyst Major Department of Medicine Medan. The purpose of this studyis to determine the Rheumatoid Factor description result on menopausal women. The result who has beenheld show there are 10 samples that obtained positive (39%) and 16 samples who obtained negative result(61%)

EXAMINATION OF CRP (C-Reactive Protein) IN OBESE TEENAGERS IN SMA MUHAMMADIYAH 02 MEDAN Ice Ratnalela Siregar
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 12 No. 2 (2017): Jurnal Ilmiah PANNMED Periode September-Desember 2017
Publisher : Poltekkes Kemenkes Medan

C-Reactive Protein (CRP) is one of the acute phase proteins present in normal serum in very little concentrations synthesized in the liver that play a role in inflammation. Obesity is a state of increase in body fat (adipocyte cells) in which adipocytes will try to maintain energy by releasing proinflammatory cytokines one of them interleukin 6 (IL-6), IL-6 release will induce CRP production in the liver. CRP examination on obese students in SMA Muhammadiyah 02 Medan.This research was conducted descriptively by Latex Aglutination method. This research was conducted at the Laboratory of Poltekkes Kemenkes Medan Health Analyst Department in May 2017 after sampling of students in SMA Muhammadiyah 02 Medan. The population of this research is 30 people of total population of 30 samples.Based on the research that has been done, the result of positive CRP examination is 18 percentage samples are 60% and 12 percent negative sample 40%. Based on sex, the result of positive CRP examination were 13 samples of female sex, 44% and 5 positive samples of male were 17%. Suggested on obese students to regularly exercise and live healthy with healthy foods also to avoid disease.

GAMBARAN HASIL PEMERIKSAAN HEPATITIS C PADA PASIEN GAGAL GINJAL KRONIK (GGK) YANG MENJALANI HEMODIALISA DI RUMAH SAKIT UNIVERSITAS SUMATERA UTARA Ice Ratnalela Siregar; Sri Wahyuni
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 17 No. 2 (2022): Jurnal Ilmiah PANNMED Periode Mei - Agustus 2022
Publisher : Poltekkes Kemenkes Medan

Chronic Kidney Disease (CKD) is a pathophysiological process with diverse etiologies, resulting in a progressive decrease in kidney function, and generally ending in renal failure. CKD is a clinical condition characterized by an irreversible decrease in kidney function that requires kidney replacement therapy in the form of dialysis or kidney transplantation. According to data from the Indonesian Nephrology Association in 2015, it is estimated that there are 90 thousand people with Chronic Kidney Disease in Indonesia, but those detected to suffer from terminal stage chronic kidneys from those undergoing dialysis (hemodialysis) are only up to five thousand to six thousand. Dialysis is a process of separating macromolecules from ions and low molecular weight compounds in solution by utilizing differences in their diffusion rates through semi-permeable membranes. One of the main techniques used in dialysis is hemodialysis. The basic principle of hemodialysis technique is the diffusion of solutes and water from plasma to dialysis solutions in response to certain differences in concentration and pressure. This technique has a risk of infection because it uses direct access to blood vessels. One of the infections that can occur in hemodialysis is infection from the hepatitis C virus. Immunochromatographic examination method ASSAY (ICA) or called the strip test (Strip Test), which is only by dripping a sample and diluents / buffer into a strip test and in certain incubation the results can already be seen with the eyes without the help of certain tools. (Standart Diagnostics, INC). Based on the sex of patients who are male infected with hepatitis C virus as many as 4 people (20%), while those who are female as many as 3 people (15%), based on the length of time to do hemodialysis, patients who are positive for Hepatitis C virus < 1 year the duration of hemodialysis is 2 people (10%), and those infected with Hepatitis C virus > 1 year as many as 5 people (25%).

GAMBARAN BASIL TAHAN ASAM PADA PENDERITA TUBERKULOSIS PARU Ice Ratnalela Siregar; Mardan Ginting; Halimah Fitriani Pane
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 16 No. 1 (2021): Jurnal Ilmiah PANNMED Periode Januari - April 2021
Publisher : Poltekkes Kemenkes Medan

ABCTRACT Tuberculosis is an acute and chronic infections disease that mainly attacks the lungs caused by acid-resistant bacteria (BTA) which are gram positive rods (Mycobacterium tuberculose). Tuberculosis can attack various organs, especially the lungs. This disease if not treated or treatment is incomplete can cause complications until death. The purpose of this study was to determine the description of Acid Resistant Basil in lung TB patients who have been diagnosed by Doctors at Puskesmas Pancurbatu Deli Serdang Regency. This research is descriptive with total population. The sample size in this study was 28 samples. Sputum speech from the study sample was examined by the Zhiel Neelsen staining method. The study was conducted at the Puskesmas Laboratory, Puskesmas Pancur Batu, Deli Serdang Regency. Data were analyzed descriptively. Based on the results of research conducted on Overview of acid-resistant bacilli (BTA) in Patients With Clinical Diagnosis OF Pulmonary Tuberculosis In Pancur Batu Public Health Center Deli Serdang District., apparently 20 samples (71%) were negative and 8 samples (29%) were positive. With the most positive results seen from the age of 17-48 years as many as 5 samples (62%) and those seen from the male Gender as many as 5 samples (62 %). Therefore it is suggested further research is needed by conducting sputum culture in patients with suspected pulmonary tuberculosis but the results of sputum smear examination are negative. Keywords : Tuberculosis, Acid Resistant Bacilli (BTA) ABSTRAK Tuberkulosis adalah penyakit menular akut maupun kronis yang terutama menyerang paru yang disebabkan oleh bakteri tahan asam (BTA) yang bersifat batang gram positif (Mycobacterium tuberculose). Tuberkulosis dapat menyerang berbagai organ terutama paru-paru. Penyakit ini jika tidak diobati atau pengobatannya tidak tuntas dapat menimbulkan komplikasi hingga kematian. Tujuan penelitian ini adalah untuk mengetahui gambaran Basil Tahan Asam Pada Penderita TB Paru yang telah di Diagnosa Dokter di Puskesmas Pancur Batu Kabupaten Deli Serdang. Penelitian ini merupakan deskriptif dengan total populasi. Besar sampel pada penelitian ini adalah 28 sampel. SpeSimen sputum dari sampel penelitian diperiksa dengan metode Pewarnaan Zhiel Neelsen. Penelitian di lakukan di Laboratorium Puskesmas Puskesmas Pancur Batu Kabupaten Deli Serdang.data hasil penelitian dianalisis secara deskriptif. Berdasrkan hasil penelitian yang telah dilaksanakan tentang Gambaran Basil Tahan Asam (BTA) Pada Penderita Diagnosa Klinis Tuberkulosis Paru Di Puskesmas Pancur Batu Kabupaten Deli Serdang, ternyata 20 sampel (71%) negatif dan 8 sampel (29%) positif. Dengan hasil positif terbanyak dilihat dari umur 17-48 tahun sebanyak 5 sampel (62%) dan yang dilihat dari Jenis Kelamin laki-laki sebanyak 5 sampel (62%). Denga demikian disarankan Perlu dilakukan penelitian lanjut dengan melakukan kultur sputum pada penderita terduga tuberkulosis paru namun hasil pemeriksaan sputum BTA negatif. Kata Kunci : Tuberkulosis, Bakteri Tahan Asam (BTA)

IDENTIFIKASI MALARIA DENGAN PROGRAM INDOOR RESIDUAL SPRAYING (IRS) WILAYAH KERJA PUSKESMAS SILAU LAUT KABUPATEN ASAHAN Ice Ratnalela Siregar; Mardan Ginting
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 18 No. 1 (2023): Jurnal Ilmiah PANNMED Periode Januari - April 2023
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36911/pannmed.v18i1.1556

Malaria is an infectious disease caused by the Plasmodium parasite that lives and reproduces in human red blood cells. This disease is naturally transmitted through the bite of a female Anopheles mosquito. Manifestation of the malaria elimination program using the Artemisinin Combination Therapy (ACT) method, prevention of malaria transmission using LLIN (Long Lasting Insecticidal Net) mosquito nets, and Indoor Residual Spraying (IRS). The purpose of this study was to determine the characteristics of malaria cases based on age, sex, microscopic examination, type of plasmodium and knowledge of respondents. pre test and post test in the IRS program in the working area of Silau Laut Health Center, Asahan Regency. The benefits of this research are expected to provide information about the incidence of malaria with the Indoor Residual Spraying (IRS) program so that it can increase community efforts to prevent malaria in the work area of the Silau Laut Health Center, Asahan Regency. The type and design of this research is Quasi Experiment with Pre and Post Test design without control.. The results of the Pre-Test knowledge of respondents in the medium category were 50 respondents (50%). The results of Post Test knowledge in the medium category increased to 60 respondents (60%). There is an effect of the intervention program on IRS on the knowledge of pre-test and post-test respondents in the work area of the Silau Laut Health Center, Asahan Regency. The Asahan District Health Office needs to conduct operational research on appropriate alternative interventions to increase the coverage of ACT treatment in endemic areas. The Health Office. More intensify all malaria prevention and eradication efforts in the work area of the Silau Laut Health Center in Asahan Regency. Vector eradication with indoor implementation Residual Spraying on a regular basis, Installing wire netting on the ventilation holes of the house. Use of insecticide-treated mosquito nets to prevent mosquito bites at night.

Peran Kesehatan Lingkungan dalam Pencegahan Penyakit Menular pada Remaja di Jakarta: Integrasi Ilmu Lingkungan, Epidemiologi, dan Kebijakan Kesehatan Nelson Tanjung; Restu Auliani; Mustar Rusli; Ice Ratnalela Siregar; M. Taher
Jurnal Multidisiplin West Science Vol 2 No 09 (2023): Jurnal Multidisiplin West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jmws.v2i09.629

Penyakit menular terus menjadi tantangan kesehatan global yang berat, dengan remaja sebagai segmen populasi yang sangat rentan. Penelitian ini menyelidiki interaksi yang rumit antara kesehatan lingkungan, epidemiologi, dan kebijakan kesehatan dalam konteks pencegahan penyakit menular di kalangan remaja di Jakarta, Indonesia. Dengan pendekatan penelitian metode campuran, yang menggabungkan survei kuantitatif dan wawancara kualitatif, penelitian ini menyelidiki berbagai dinamika yang membentuk lanskap kesehatan remaja di Jakarta. Temuan ini menggarisbawahi peran penting faktor lingkungan dalam penularan penyakit menular. Polusi udara, kurangnya akses terhadap air bersih, dan sanitasi yang buruk muncul sebagai faktor risiko lingkungan yang signifikan, yang mempengaruhi prevalensi penyakit. Analisis epidemiologi menunjukkan pola yang berbeda, dengan demam berdarah menjadi perhatian utama, terutama selama musim hujan. Kajian terhadap kebijakan kesehatan menunjukkan adanya tantangan dalam pelaksanaannya, yang disebabkan oleh keterbatasan sumber daya dan kesenjangan kesadaran. Studi ini mengadvokasi pendekatan terpadu yang mengakui keterkaitan antara ilmu lingkungan, epidemiologi, dan kebijakan kesehatan. Rekomendasi yang diberikan mencakup peningkatan perencanaan kota, peraturan kualitas udara, infrastruktur kesehatan yang lebih baik, dan pelibatan masyarakat untuk mengoptimalkan efektivitas kebijakan. Dengan mendorong kolaborasi interdisipliner dan penyesuaian kebijakan berbasis bukti, Jakarta dapat mengambil langkah substantif untuk melindungi kesehatan dan kesejahteraan populasi remaja dalam menghadapi penyakit menular. Temuan ini berkontribusi pada wacana yang lebih luas tentang intervensi kesehatan masyarakat yang komprehensif, yang menekankan pentingnya strategi holistik untuk mengatasi tantangan kesehatan yang rumit. Penelitian lebih lanjut dan tindakan kebijakan diperlukan untuk membangun wawasan ini dan meningkatkan hasil kesehatan remaja Jakarta.

ANALYSIS OF URINE MICROALBUMIN LEVELS ON SERUM CREATININE IN PATIENTS WITH DIABETES MELLITUS IN THE CLINICAL LABORATORY OF MEDAN PRODIA Ice Ratnalela Siregar; Yunilasari Hasibuan; Melika Ostina Purba
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 18 No. 2 (2023): Jurnal Ilmiah PANNMED Periode Mei - Agustus 2023
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36911/pannmed.v18i2.1604

Diabetes Mellitus is a degenerative disease that requires regular control. This disease occurs due to the pancreas not being able to produce enough insulin and/or when the body cannot produce insulin effectively so that it can cause various complications in the patient's organs. The purpose of this study was to determine the levels of Urine Microalbumin and Serum Creatinine at Prodia Clinical Laboratory Jl. Lt. Gen. S. Parman No. 17/223 G Medan. This research was conducted from August to October 2022 at the Clinical Laboratory of Prodia Medan. This type of research is descriptive Cross Sectional. This examination uses Immunoturbidimetric and Enzymatic Colorimetric methods with a total sample of 100 samples or the total of the population. The results of the research conducted showed that the number of Diabetes Mellitus patients at the Prodia Clinical Laboratory in Medan with gender as many as 48 men (48%) and 52 women (52%) samples. Normal Urine Microalbumin levels were 30 samples (30%) and High Urine Microalbumin levels were 70 samples (70%). Normal creatinine levels were 47 samples (47%) and abnormal creatinine levels were 53 samples (53%).

RELATIONSHIP OF PROTEIN INPUT, VITAMIN C, FE WITH BLOOD COMPONENTS (HB, LEUKOSITES, AND HEMATOCRITES) IN SOCCER ATHLETES AT PPLP MEDAN Ginta Siahaan; Mahdiah Mahdiah; Ice Ratnalela Siregar; Yuni Ghretella Agrisalita Sinaga
MEDIKORA Vol 22, No 2 (2023): Oktober
Publisher : Faculty of Sports Sciences, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/medikora.v22i2.65909

Football is an achievement sport and widely played throughout the world by all age groups, races and genders. Minerals and vitamins are nutrients that football athletes should consume because they contain antioxidants that can neutralize oxidative stress. Meanwhile, protein functions as an antibody and replaces cells damaged due to injuries experienced by a soccer athlete. This study aims to determine the relationship between protein intake, vitamin C, Fe and blood components (Hb, leukocytes and hematocrit) on football athletes at PPLP Medan. This study using descriptive observational with design cross sectional , that isanalyze the relationship between protein intake, vitamin C, Fe and blood components (Hb, leukocytes, and hematocrit) football athlete (PPLP) Medan . The entire population was sampled, totaling 33 people, both core and reserve players. Protein, vitamin C and Fe intake were significantly related to Hb p- value 0.05. Meanwhile, protein and Fe intake were significantly related to hematocrit, while vitamin C was not related (p- value 0.05). Meanwhile, protein and vitamin C intake was significantly related to leukocytes, but Fe was not (p- value 0.05). There is a relationship between protein, Fe and vitamin C intake with hemoglobin levels based on the Pearson correlation statistical test analysis . There is a relationship between Protein and Fe intake and hematocrit based on the Pearson correlation statistical test analysis. There is a relationship between protein and vitamin C intake with leukocytes based on the Pearson correlation statistical test analysis.

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